List of works by Jalal Taneera

A central role for GRB10 in regulation of islet function in man.

scientific article published on 3 April 2014

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

scientific article published on January 2011

A common variant upstream of the PAX6 gene influences islet function in man.

scientific article published on 16 September 2011

A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

scientific article

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

scientific article published on 07 July 2009

An Integrative Phenotype-Genotype Approach Using Phenotypic Characteristics from the UAE National Diabetes Study Identifies HSD17B12 as a Candidate Gene for Obesity and Type 2 Diabetes

scientific article published on 23 April 2020

Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets

scientific article published on 09 August 2013

Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation

scientific article

Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes

scientific article

Downregulation of type II diabetes mellitus and maturity onset diabetes of young pathways in human pancreatic islets from hyperglycemic donors.

scientific article

Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans

scientific article published on 4 April 2013

Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta

scientific article published on 18 December 2009

Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors

scientific article published on 07 August 2020

Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes

scientific article published on 22 May 2013

Failure of transplanted bone marrow cells to adopt a pancreatic beta-cell fate

scientific article published in February 2006

GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells

scientific article published on 30 July 2019

Genetic Variants of the PLCXD3 Gene Are Associated with Risk of Metabolic Syndrome in the Emirati Population

scientific article published on 18 June 2020

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

scientific article

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets

scientific article

Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke

scientific article published in June 2009

Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction

scientific article published on 21 September 2019

Pleiotropic effects of GIP on islet function involve osteopontin

scientific article

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.

scientific article published on 23 August 2012

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

scientific article

Silencing of the FTO gene inhibits insulin secretion: An in vitro study using GRINCH cells.

scientific article published on 8 June 2018

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion

scientific article published on 21 September 2009

γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes

scientific article