List of works by Paolo Manunta

A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.

scientific article published on 7 August 2013

A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia

scientific article

A new antihypertensive agent that antagonizes the prohypertensive effect of endogenous ouabain and adducin

scientific article

A new clinical multivariable model that predicts postoperative acute kidney injury: impact of endogenous ouabain

scientific article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

ACE and α-Adducin Polymorphism as Markers of Individual Response to Diuretic Therapy

article

ADDing a piece to the puzzle of cognition in schizophrenia.

scientific article

Adducin in essential hypertension

scientific article published in June 1998

Adducin polymorphisms and the treatment of hypertension

scientific article published on May 2007

Adducin, Renal Intermediate Phenotypes, and Hypertension

Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies

scientific article published on November 2010

Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients.

scientific article published on June 1998

Angiotensin-converting enzyme I/D and alpha-adducin Gly460Trp polymorphisms: from angiotensin-converting enzyme activity to cardiovascular outcome

scientific article published on 23 April 2007

Are Retinal Microvascular Phenotypes Associated With the 1675G/A Polymorphism in the Angiotensin II Type-2 Receptor Gene?

article

Are the new single nucleotide polymorphisms (SNPs) relevant for hypertensive populations?

scientific article published on 01 December 2002

Arterial properties in relation to genetic variation in alpha-adducin and the renin-angiotensin system in a White population

scientific article

Arterial properties in relation to genetic variations in the adducin subunits in a white population

scientific article

Association Between Arterial Properties and Renal Sodium Handling in a General Population

article

Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.

scientific article published on 12 July 2006

Association of echocardiographic left ventricular structure with the ACE D/I polymorphism: a meta-analysis

scientific article published on 27 January 2011

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Beta-adducin and sodium-calcium exchanger 1 gene variants are associated with systemic lupus erythematosus and lupus nephritis

scientific article published on 05 June 2015

Cardiac glycosides and cardiomyopathy

scientific article published on 6 February 2006

Changes in mass and energy transfer between the canopy and the atmosphere: model development and testing with a free-air CO2 enrichment (FACE) experiment

scientific article published on February 2002

Clinical impact of adducin polymorphism

scientific article

Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension

scientific article

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

scientific article

Coronary risk in relation to genetic variation in MEOX2 and TCF15 in a Flemish population

scientific article published on October 2015

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

scientific article

Deciphering Variability of PKD1 and PKD2 in an Italian Cohort of 643 Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD).

scientific article published on 8 August 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Different effects of marinobufagenin and endogenous ouabain

scientific article published in February 2004

Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity

scientific article

Efficacy and tolerability of doxazosin alone or in combination with chlorthalidone in essential hypertension

Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases

article

Endogenous Ouabain: An Old Cardiotonic Steroid as a New Biomarker of Heart Failure and a Predictor of Mortality after Cardiac Surgery.

scientific article published on November 2015

Endogenous cardiotonic steroids in kidney failure: a review and an hypothesis

scientific article published on May 2015

Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension

scientific article published on 01 October 2016

Endogenous ouabain and cardiomyopathy in dialysis patients

scientific article

Endogenous ouabain and hemodynamic and left ventricular geometric patterns in essential hypertension

scientific article published on 01 January 2001

Endogenous ouabain and the renin-angiotensin-aldosterone system: distinct effects on Na handling and blood pressure in human hypertension

scientific article

Endogenous ouabain in Ménière's disease.

scientific article published in January 2010

Endogenous ouabain in cardiovascular function and disease

scientific article published on January 2009

Endogenous ouabain in renal Na(+) handling and related diseases

scientific article

Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis

scientific article

Endogenous ouabain: a link between sodium intake and hypertension

scientific article

Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.

scientific article

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

scientific article

Genetic burden of common variants in progressive and bout-onset multiple sclerosis

scientific article published on 28 November 2013

Genetic evidence of assortative mating in humans

article

Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci.

scientific article published on 09 February 2017

Genetics of essential hypertension: from families to genes

scientific article

Genetics of ion homeostasis in Ménière's Disease.

scientific article published on 11 November 2016

Genetics of primary hypertension: the clinical impact of adducin polymorphisms.

scientific article published on 08 April 2010

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

scientific article published on 31 October 2016

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase

scientific article published on 19 December 2011

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide

scientific article published on 10 June 2013

Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers.

scientific article

Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.

scientific article

Heat wave hazard classification and risk assessment using artificial intelligence fuzzy logic

scientific article

Hypertension in High School Students: Genetic and Environmental Factors: The HYGEF Study

scientific article published on 25 November 2019

Immunoreactive endogenous ouabain primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels

article

Inactive Matrix Gla Protein Is Causally Related to Adverse Health Outcomes

article

Independent and incremental prognostic value of endogenous ouabain in idiopathic dilated cardiomyopathy

article

Ion Channels and Transporters in Inflammation: Special Focus on TRP Channels and TRPC6

Klotho Gene in Human Salt-Sensitive Hypertension

scientific article published on 28 January 2020

Lanosterol Synthase Gene Polymorphisms and Changes in Endogenous Ouabain in the Response to Low Sodium Intake.

scientific article

Lanosterol Synthase Genetic Variants, Endogenous Ouabain, and Both Acute and Chronic Kidney Injury

scientific article published on 16 January 2019

Left ventricular geometry and endogenous ouabain in a Flemish population

article

Left ventricular radial function associated with genetic variation in the cGMP-dependent protein kinase.

scientific article

Left ventricular structure and function in relation to steroid biosynthesis genes in a white population.

scientific article published on 7 June 2012

Low-salt diet and diuretic effect on blood pressure and organ damage

scientific article published on January 2004

MPO antibody-positive vasculitis in a patient with psoriatic arthritis and gold-induced membranous glomerulonephritis

scientific article published in August 1998

Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin

scientific article

MicroRNA 193b-3p as a predictive biomarker of chronic kidney disease in patients undergoing radical nephrectomy for renal cell carcinoma.

scientific article

Na+, kidney, hypertension and genes

article

OASIS-HT: design of a pharmacogenomic dose-finding study

scientific article

Ouabain Contributes to Kidney Damage in a Rat Model of Renal Ischemia-Reperfusion Injury

scientific article published on 14 October 2016

Ouabain-like factor: is this the natriuretic hormone?

scientific article

Personalized Therapy of Hypertension: the Past and the Future

scientific article published on March 2016

Pharmacogenomics and pharmacogenetics of hypertension: update and perspectives--the adducin paradigm

scientific article

Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice

scientific article published on 26 November 2020

Physiological Interaction Between α-Adducin and WNK1-NEDD4L Pathways on Sodium-Related Blood Pressure Regulation

Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension

scientific article (publication date: 10 May 1997)

Polymorphisms, hypertension and thiazide diuretics.

scientific article

Predicting acute kidney injury: current status and future challenges

scientific article published on 17 June 2017

Preoperative endogenous ouabain predicts acute kidney injury in cardiac surgery patients

scientific article published on March 2013

Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1.

scientific article

Quantitative proteomics reveals novel therapeutic and diagnostic markers in hypertension.

scientific article

Recognition of markers of response to potassium-canrenoate in essential hypertension

scientific article published on 01 January 1995

Relationships among endogenous ouabain, alpha-adducin polymorphisms and renal sodium handling in primary hypertension.

scientific article

Reply: "Comment on: Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases" ⬇️

article

Role of the adducin family genes in human essential hypertension

scientific article (publication date: March 2005)

Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain.

scientific article published on 3 September 2014

SIK1 localizes with nephrin in glomerular podocytes and its polymorphism predicts kidney injury.

scientific article published on 11 November 2014

Salt Sensitivity: Challenging and Controversial Phenotype of Primary Hypertension

scientific article published on September 2016

Salt intake and depletion increase circulating levels of endogenous ouabain in normal men.

scientific article published in March 2006

Salt, endogenous ouabain and blood pressure interactions in the general population

scientific article published in August 2003

Steroid biosynthesis and renal excretion in human essential hypertension: association with blood pressure and endogenous ouabain.

scientific article

Synergistic effect of α-adducin and ACE genes causes blood pressure changes with body sodium and volume expansion

article

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

scientific article published on June 2015

TRPC6 gene variants and neuropsychiatric lupus.

scientific article published on 28 August 2015

Target sequencing, cell experiments, and a population study establish endothelial nitric oxide synthase (eNOS) gene as hypertension susceptibility gene

scientific article published on 9 September 2013

Targeting Ouabain- and Adducin-dependent mechanisms of hypertension and cardiovascular remodeling as a novel pharmacological approach

scientific article published on 9 November 2006

The -665 C>T polymorphism in the eNOS gene predicts cardiovascular mortality and morbidity in white Europeans

scientific article published on 7 August 2014

The TRPC6 intronic polymorphism, associated with the risk of neurological disorders in systemic lupus erythematous, influences immune cell function

scientific article published on 23 October 2018

The clinical pathway for hypertensive patient of local health unit, hospitals and general practitioners, the Milan experience

scientific article published on January 2011

The endogenous ouabain: molecular basis of its role in hypertension and cardiovascular complications

scientific article

The risk of nephrolithiasis is causally related to inactive matrix Gla protein, a marker of vitamin K status: a Mendelian randomization study in a Flemish population

scientific article published on 15 March 2017

The role of adducin in hypertension

The young girl with renovascular hypertension of unknown origin

scientific article published on 01 April 1997

Urinary neutrophil gelatinase-associated lipocalin time course during cardiac surgery.

scientific article published on January 2015

Xanthine oxidase gene variants and their association with blood pressure and incident hypertension: a population study

scientific article published on 6 September 2016

[Psychological Assessment of a sample of women with ADPKD: quality of life, body image, anxiety and depression]

scientific article published on 01 April 2019

alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy

scientific article

cGMP-dependent protein kinase 1 polymorphisms underlie renal sodium handling impairment.

scientific article

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