List of works - Giovanni Malerba

A Preliminary microRNA Analysis of Non Syndromic Thoracic Aortic Aneurysms.

scientific article published on December 2012

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

scientific article

ALOX5AP gene variants and risk of coronary artery disease: an angiography-based study

article

An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis

scientific article published on 06 November 2014

Analysis of RBFOX1 gene expression in lymphoblastoid cell lines of Italian discordant autism spectrum disorders sib-pairs

scientific article

Analysis of the 3'UTR of the prostaglandin synthetase-2 (PTGS-2/COX-2) gene in non-melanoma skin cancer after organ transplantation

scientific article

Application of the whole-transcriptome shotgun sequencing approach to the study of Philadelphia-positive acute lymphoblastic leukemia.

scientific article published on 9 March 2012

Association of CTR and COLIA1 Alleles with BMD Values in Peri- and Postmenopausal Women

scientific article published on 01 November 2000

Association of childhood allergic asthma with markers flanking the IL33 gene in Italian families

scientific article

Association of functional gene variants in the regulatory regions of COX-2 gene (PTGS2) with nonmelanoma skin cancer after organ transplantation

scientific article

Association of microRNA 146a polymorphism rs2910164 and the risk of melanoma in an Italian population

article

Association of promoter polymorphism -765G>C in the PTGS2 gene with malignant melanoma in Italian patients and its correlation to gene expression in dermal fibroblasts.

scientific article published in October 2014

CACNA1E variants affect beta cell function in patients with newly diagnosed type 2 diabetes. the Verona newly diagnosed type 2 diabetes study (VNDS) 3

scientific article

COX-2 promoter region polymorphisms in multiple sclerosis: lack of association of ?765G>C with disease risk

scientific article published on 01 April 2007

Characterization of transcriptional complexity during berry development in Vitis vinifera using RNA-Seq.

scientific article published on 29 January 2010

Chromosome 14 linkage analysis and mutation study of 2 serpin genes in allergic asthmatic families

scientific article published in April 2001

Chromosome 7p linkage and GPR154 gene association in Italian families with allergic asthma

scientific article

Cyclooxygenase 2, toll-like receptor 4 and interleukin 1β mRNA expression in atherosclerotic plaques of type 2 diabetic patients

scientific article published on 06 August 2014

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

scientific article published on 26 September 2016

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Enhanced Osteogenic Differentiation in Zoledronate-Treated Osteoporotic Patients

scientific article

Eotaxin/CCL11 in idiopathic retroperitoneal fibrosis

scientific article published on 01 October 2012

Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

scientific article published on 12 May 2015

Fully non-homogeneous hidden Markov model double net: a generative model for haplotype reconstruction and block discovery

scientific article published on 23 October 2008

Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease

scientific article (publication date: 5 September 2007)

Genetic and bioinformatics analysis of four novel GCK missense variants detected in Caucasian families with GCK-MODY phenotype.

scientific article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic susceptibility to renal scar formation after urinary tract infection: a systematic review and meta-analysis of candidate gene polymorphisms

scientific article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Glutathione S-transferase and CYP1A1 gene polymorphisms and non-melanoma skin cancer risk in Italian transplanted patients

scientific article

HDAC9, TWIST1 and FERD3L gene expression in asymptomatic stable and unstable carotid plaques.

scientific article published on 30 November 2015

IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C.

scientific article published on 28 March 2011

IRAK-M is involved in the pathogenesis of early-onset persistent asthma

scientific article

Impact of Insulin Receptor Substrate-1 Genotypes on Platelet Reactivity and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease

scholarly article by Dominick J. Angiolillo et al published June 2011 in Journal of the American College of Cardiology

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

scientific article

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

scientific article

Lack of expression of TUBB3 characterizes both BCL2-positive and BCL2-negative follicular lymphoma.

scientific article

Linkage to atopy on chromosome 19 in north-eastern Italian families with allergic asthma

article

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy

scientific article

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Mutational and haplotype map of NOTCH3 in a cohort of Italian patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

scientific article published on 3 June 2012

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

Next generation sequencing: new tools in immunology and hematology

scientific article

No linkage or association of five polymorphisms in the interleukin-4 receptor alpha gene with atopic asthma in Italian families

scientific article

On the association of the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction or coronary artery disease

article

PPARG2 Pro12Ala and ADAMTS9 rs4607103 as “insulin resistance loci” and “insulin secretion loci” in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4

article

PTCH1 gene haplotype association with basal cell carcinoma after transplantation

scientific article

PTPN22 R620W polymorphism in the ANCA-associated vasculitides

scientific article published on 11 January 2012

Polymorphism -2604G>A variants in TLR4 promoter are associated with different gene expression level in peripheral blood of atherosclerotic patients.

scientific article published on 10 October 2013

Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile

scientific article published in September 2010

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Relationship among VDR (BsmI and FokI), COLIA1, and CTR polymorphisms with bone mass, bone turnover markers, and sex hormones in men.

scientific article

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease

scientific article published on 5 March 2008

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

scientific article

Small effective population size and genetic homogeneity in the Val Borbera isolate.

scientific article

The association of rs4307059 and rs35678 markers with autism spectrum disorders is replicated in Italian families

scientific article published in August 2012

The genetic background of osteoporosis in cystic fibrosis: Association analysis with polymorphic markers in four candidate genes

article

The −1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study

article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Upregulated Expression of Toll-like Receptor 4 in Peripheral Blood of Ischaemic Stroke Patients Correlates with Cyclooxygenase 2 Expression

scientific article published on 13 January 2011

Variants and haplotypes of TCF7L2 are associated with β-cell function in patients with newly diagnosed type 2 diabetes: the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 1.

scientific article published on 15 December 2010

Variants of GCKR affect both β-cell and kidney function in patients with newly diagnosed type 2 diabetes: the Verona newly diagnosed type 2 diabetes study 2.

scientific article

Wheat IgE profiling and wheat IgE levels in bakers with allergic occupational phenotypes

scientific article published on 17 May 2013

α1-Antitrypsin TAQ I polymorphism and α1-antichymotrypsin mutations in patients with obstructive pulmonary disease

scientific article published on 01 September 1999

List of works by Giovanni Malerba

A Preliminary microRNA Analysis of Non Syndromic Thoracic Aortic Aneurysms.

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

ALOX5AP gene variants and risk of coronary artery disease: an angiography-based study

An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis

Analysis of RBFOX1 gene expression in lymphoblastoid cell lines of Italian discordant autism spectrum disorders sib-pairs

Analysis of the 3'UTR of the prostaglandin synthetase-2 (PTGS-2/COX-2) gene in non-melanoma skin cancer after organ transplantation

Application of the whole-transcriptome shotgun sequencing approach to the study of Philadelphia-positive acute lymphoblastic leukemia.

Association of CTR and COLIA1 Alleles with BMD Values in Peri- and Postmenopausal Women

Association of childhood allergic asthma with markers flanking the IL33 gene in Italian families

Association of functional gene variants in the regulatory regions of COX-2 gene (PTGS2) with nonmelanoma skin cancer after organ transplantation

Association of microRNA 146a polymorphism rs2910164 and the risk of melanoma in an Italian population

Association of promoter polymorphism -765G>C in the PTGS2 gene with malignant melanoma in Italian patients and its correlation to gene expression in dermal fibroblasts.

CACNA1E variants affect beta cell function in patients with newly diagnosed type 2 diabetes. the Verona newly diagnosed type 2 diabetes study (VNDS) 3

COX-2 promoter region polymorphisms in multiple sclerosis: lack of association of ?765G>C with disease risk

Characterization of transcriptional complexity during berry development in Vitis vinifera using RNA-Seq.

Chromosome 14 linkage analysis and mutation study of 2 serpin genes in allergic asthmatic families

Chromosome 7p linkage and GPR154 gene association in Italian families with allergic asthma

Cyclooxygenase 2, toll-like receptor 4 and interleukin 1β mRNA expression in atherosclerotic plaques of type 2 diabetic patients

Directional dominance on stature and cognition in diverse human populations

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Enhanced Osteogenic Differentiation in Zoledronate-Treated Osteoporotic Patients

Eotaxin/CCL11 in idiopathic retroperitoneal fibrosis

Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

Fully non-homogeneous hidden Markov model double net: a generative model for haplotype reconstruction and block discovery

Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease

Genetic and bioinformatics analysis of four novel GCK missense variants detected in Caucasian families with GCK-MODY phenotype.

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Genetic susceptibility to renal scar formation after urinary tract infection: a systematic review and meta-analysis of candidate gene polymorphisms

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

Glutathione S-transferase and CYP1A1 gene polymorphisms and non-melanoma skin cancer risk in Italian transplanted patients

HDAC9, TWIST1 and FERD3L gene expression in asymptomatic stable and unstable carotid plaques.

IL28B polymorphisms, IP-10 and viral load predict virological response to therapy in chronic hepatitis C.

IRAK-M is involved in the pathogenesis of early-onset persistent asthma

Impact of Insulin Receptor Substrate-1 Genotypes on Platelet Reactivity and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

Lack of expression of TUBB3 characterizes both BCL2-positive and BCL2-negative follicular lymphoma.

Linkage to atopy on chromosome 19 in north-eastern Italian families with allergic asthma

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy

Modulation of genetic associations with serum urate levels by body-mass-index in humans

Mutational and haplotype map of NOTCH3 in a cohort of Italian patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Next generation sequencing: new tools in immunology and hematology

No linkage or association of five polymorphisms in the interleukin-4 receptor alpha gene with atopic asthma in Italian families

On the association of the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction or coronary artery disease

PPARG2 Pro12Ala and ADAMTS9 rs4607103 as “insulin resistance loci” and “insulin secretion loci” in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4

PTCH1 gene haplotype association with basal cell carcinoma after transplantation

PTPN22 R620W polymorphism in the ANCA-associated vasculitides

Polymorphism -2604G>A variants in TLR4 promoter are associated with different gene expression level in peripheral blood of atherosclerotic patients.

Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Relationship among VDR (BsmI and FokI), COLIA1, and CTR polymorphisms with bone mass, bone turnover markers, and sex hormones in men.

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

Small effective population size and genetic homogeneity in the Val Borbera isolate.

The association of rs4307059 and rs35678 markers with autism spectrum disorders is replicated in Italian families

The genetic background of osteoporosis in cystic fibrosis: Association analysis with polymorphic markers in four candidate genes

The −1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Upregulated Expression of Toll-like Receptor 4 in Peripheral Blood of Ischaemic Stroke Patients Correlates with Cyclooxygenase 2 Expression

Variants and haplotypes of TCF7L2 are associated with β-cell function in patients with newly diagnosed type 2 diabetes: the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 1.

Variants of GCKR affect both β-cell and kidney function in patients with newly diagnosed type 2 diabetes: the Verona newly diagnosed type 2 diabetes study 2.

Wheat IgE profiling and wheat IgE levels in bakers with allergic occupational phenotypes

α1-Antitrypsin TAQ I polymorphism and α1-antichymotrypsin mutations in patients with obstructive pulmonary disease