List of works by Robert Sladek

A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease

scientific article published on 28 May 2015

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study identifies novel risk loci for type 2 diabetes

scientific article

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

scientific article

A methodology for global validation of microarray experiments

scientific article

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

scientific article

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels

scientific article published in May 2008

A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men.

scientific article

A survey of genetic and epigenetic variation affecting human gene expression

scientific article published on 15 January 2004

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

scientific article

Altered gene expression in cells from patients with lysosomal storage disorders suggests impairment of the ubiquitin pathway

scientific article published on 4 August 2006

Alternative Splicing of the Delta-Opioid Receptor Gene Suggests Existence of New Functional Isoforms

article

Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection

scientific article published on 06 September 2016

An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria

scientific article

An electrochemically controlled microcantilever biosensor

scientific article published on 29 July 2013

Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and culture

scientific article

Application of expression microarrays to the investigation of fetal lung development in a glucocorticoid receptor knockout mouse model.

scientific article published in March 2002

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article (publication date: June 2014)

Bioinformatics in research and clinical practice

article

Characterization of a FOXG1:TLE1 transcriptional network in glioblastoma initiating cells.

scientific article published on 9 January 2018

Characterization of variability in large-scale gene expression data: implications for study design

scientific article

Characterizing the profile of obese patients who are metabolically healthy

scientific article published on 26 October 2010

Chromosomal mapping of the human and murine orphan receptors ERRalpha (ESRRA) and ERRbeta (ESRRB) and identification of a novel human ERRalpha-related pseudogene

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Comparison of the effects of Leishmania major or Leishmania donovani infection on macrophage gene expression

scientific article published on 17 December 2007

Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death

scientific article published on April 2006

Control genes and variability: absence of ubiquitous reference transcripts in diverse mammalian expression studies

scientific article

Convex lens-induced nanoscale templating

scientific article

Denaturation mapping of Saccharomyces cerevisiae.

scientific article published on 23 July 2012

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Development of a platform for single cell genomics using convex lens-induced confinement.

scientific article published in June 2015

Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression

scientific article

Elucidating cis- and trans-regulatory variation using genetical genomics

scientific article

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

scientific article

Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation

scientific article

Functional classes of bronchial mucosa genes that are differentially expressed in asthma

scientific article

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.

scientific article published on 8 December 2013

Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits

scientific article published on 03 August 2009

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

scientific article published on 6 September 2009

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

scholarly article

Genome-wide analysis of transcript isoform variation in humans

scientific article

Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.

scientific article published on 8 July 2007

Glucolipotoxicity alters lipid partitioning and causes mitochondrial dysfunction, cholesterol, and ceramide deposition and reactive oxygen species production in INS832/13 ss-cells

scientific article published on 5 May 2010

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

scientific article

Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells.

scientific article

Identification of novel chromosomal regions associated with airway hyperresponsiveness in recombinant congenic strains of mice

scientific article published on 15 December 2009

Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans

article

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Increased subcutaneous adipose tissue expression of genes involved in glycerolipid-fatty acid cycling in obese insulin-resistant versus -sensitive individuals

scientific article

Independent test assessment using the extreme value distribution theory

scientific article published on 18 October 2016

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

scientific article

Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling

scientific article published on 01 August 2018

Lipopolysaccharide and TNF-alpha produce very similar changes in gene expression in human endothelial cells.

scientific article

Low copy number of the salivary amylase gene predisposes to obesity.

scientific article published on 30 March 2014

Mapping cis-acting regulatory variation in recombinant congenic strains

article

Mapping of Clinical and Expression Quantitative Trait Loci in a Sex-Dependent Effect of Host Susceptibility to Mouse-Adapted Influenza H3N2/HK/1/68

Mapping of a chromosome 12 region associated with airway hyperresponsiveness in a recombinant congenic mouse strain and selection of potential candidate genes by expression and sequence variation analyses

scientific article

Mapping of novel chromosomal regions associated with atopy.

scientific article published on 3 March 2014

Microarray analysis of uterine gene expression in mouse and human pregnancy

scientific article

Modulation of the allergic asthma transcriptome following resiquimod treatment.

scientific article published on 2 June 2009

Molecular diagnosis of neonatal diabetes mellitus using next-generation sequencing of the whole exome.

scientific article

Morphogenetic plasticity of adult human pancreatic islets of Langerhans

scientific article published in July 2005

Mouse Chromosome 4 Is Associated with the Baseline and Allergic IgE Phenotypes

scientific article published on 10 July 2017

Multilevel space-time aggregation for bright field cell microscopy segmentation and tracking

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Orphan nuclear receptors: an emerging family of metabolic regulators.

scientific article

Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression

scientific article

Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta

scientific journal article

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value

scientific article published in 2008

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes

scientific article published on 29 January 2012

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha

scientific article

Rel-Dependent Immune and Central Nervous System Mechanisms Control Viral Replication and Inflammation during Mouse Herpes Simplex Encephalitis

scientific article published on 25 January 2019

Sex-specific effects of a microsatellite polymorphism on human growth hormone receptor gene expression

scientific article published on 04 May 2019

Small deletion variants have stable breakpoints commonly associated with alu elements.

scientific article

TFCat: the curated catalog of mouse and human transcription factors

scientific article (publication date: 2009)

The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development

scientific journal article

The many faces of diabetes: addressing heterogeneity of a complex disease.

scientific article published in March 2018

The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene.

scientific article published on September 1997

The protein kinase PKR: a molecular clock that sequentially activates survival and death programs

scientific article

Transverse dielectrophoretic-based DNA nanoscale confinement.

scientific article published on 13 April 2018

Vav-1 expression correlates with NFκB activation and CD40-mediated cell death in diffuse large B-cell lymphoma cell lines

scientific article

cnvHap: an integrative population and haplotype-based multiplatform model of SNPs and CNVs

scientific article published on 30 May 2010

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