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List of works by Yann Hérault

A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse

scholarly article published 19 June 2017

A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice.

scientific article

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

scientific article published on 24 January 2020

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

scientific article

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

scientific article published on 12 October 2017

A nested deletion approach to generate Cre deleter mice with progressive Hox profiles.

scientific article published on January 2002

A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

scientific article published on 26 September 2009

A new mouse model of ARX dup24 recapitulates the patients' behavioural and fine motor alterations

scientific article published on 5 April 2018

A suppressor locus for MODY3-diabetes

scientific article published on 26 September 2016

Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes.

scientific article

Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice

scientific article published on 01 March 2019

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

scientific article

Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction

scientific article

Aneuploidy: from a physiological mechanism of variance to Down syndrome

scientific article published on July 2009

Applying the ARRIVE Guidelines to an In Vivo Database

scientific article

Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies

scientific article

BIN1 genetic risk factor for Alzheimer is sufficient to induce early structural tract alterations in entorhinal cortex-dentate gyrus pathway and related hippocampal multi-scale impairments

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

scientific article published on 07 May 2019

Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a

Cbs overdosage is necessary and sufficient to induce cognitive phenotypes in mouse models of Down syndrome and interacts genetically with Dyrk1a

scientific article published on 01 May 2019

Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB

scientific article

Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in Down syndrome

scientific article

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration

scientific article

Control of limb morphogenesis by the Hox genes

scientific article published in January 1997

Controlled somatic and germline copy number variation in the mouse model

scientific article

Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A

scientific article published on 27 September 2018

Corrigendum: Domains of genome-wide gene expression dysregulation in Down’s syndrome

scientific article published in Nature

Corrigendum: High-throughput discovery of novel developmental phenotypes.

scientific article published on 8 November 2017

DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels

scientific article

DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome

scientific article

DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase

scientific article

DYRK1A: a master regulatory protein controlling brain growth.

scientific article published on 26 January 2012

Deletion of the App-Runx1 region in mice models human partial monosomy 21.

scientific article published on 16 April 2015

Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.

scientific article published on 28 November 2013

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

scientific article published on 26 June 2017

Distinct fibroblast lineages determine dermal architecture in skin development and repair.

scientific article

Domains of genome-wide gene expression dysregulation in Down's syndrome.

scientific article published in April 2014

Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome

scientific article

Down syndrome: from understanding the neurobiology to therapy

scientific article

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature

scientific article published on 2 August 2017

Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance.

scientific article published on 28 May 2014

E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.

scientific article published on 12 September 2016

EMMA--mouse mutant resources for the international scientific community

scientific article

Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE

scientific article published on 07 March 2017

Engineering chromosomes in mice through targeted meiotic recombination (TAMERE)

scientific article published on 01 December 1998

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

scientific article published on 14 September 2013

Erratum: A suppressor locus for MODY3-diabetes

scientific article published on 21 October 2016

Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts

scientific article published on 07 March 2019

Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells

scientific article published in December 2002

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage

scientific article published on 4 May 2014

FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents: a report of the Federation of European Laboratory Animal Science Associations Working Group

scientific article published on 01 July 2013

Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability

scientific article published on 4 May 2016

Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors

scientific article published on 28 November 2016

Fork stalling and template switching as a mechanism for polyalanine tract expansion affecting the DYC mutant of HOXD13, a new murine model of synpolydactyly

scientific article published on 22 June 2009

Gdaphen, R pipeline to identify the most important qualitative and quantitative predictor variables from phenotypic data

scientific article published in 2023

Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development

scientific article

Genetic control of limb development

scientific article published in January 1996

Genetic quality assurance and genetic monitoring of laboratory mice and rats: FELASA Working Group Report

scientific article published on 20 August 2019

Genetics of dark skin in mice

scientific article

HENA, heterogeneous network-based data set for Alzheimer's disease

scientific article published on 14 August 2019

HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models

scientific article published in 2022

Heme oxygenase-1 accelerates cutaneous wound healing in mice

scientific article

Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45β-dependent manner

scientific article published on 25 June 2018

Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder

scientific article published on 15 July 2014

High Resolution Episcopic Microscopy for Qualitative and Quantitative Data in Phenotyping Altered Embryos and Adult Mice Using the New “Histo3D” System

scientific article published in 2021

High-throughput discovery of genetic determinants of circadian misalignment

scientific article published on 13 January 2020

High-throughput discovery of novel developmental phenotypes

scientific article published on 14 September 2016

Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background

scientific article published on 20 March 2012

How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains

scientific article

Hox gene expression in limbs: colinearity by opposite regulatory controls.

scientific article

Human and mouse essentiality screens as a resource for disease gene discovery

scientific article published on 31 January 2020

Identification of genes required for eye development by high-throughput screening of mouse knockouts

scientific article published on 21 December 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

scientific article published on 18 January 2018

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome

scientific article published on 28 September 2011

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

scientific article

Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome

scientific article published on 15 March 2018

Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination

scientific article published on 30 August 2008

Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus

scientific article published on 22 December 2017

Introduction to Mammalian Genome Special Issue: Genome Editing

scientific article published on 01 August 2017

KIT is required for hepatic function during mouse post-natal development

scientific article

LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.

scientific article published on 19 August 2015

Long-lasting correction of in vivo LTP and cognitive deficits of mice modelling Down syndrome with an α5-selective GABAA inverse agonist

scientific article published on 09 January 2020

Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development

scientific article

Modeling Down syndrome in animals from the early stage to the 4.0 models and next

scientific article published on 22 October 2019

Modeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organization

scientific article published in July 2006

Modeling human disease in rodents by CRISPR/Cas9 genome editing

scientific article published on 4 July 2017

Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses

scientific article published on 25 June 2007

Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project

scientific article

Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition.

scientific article published on 13 July 2017

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

scientific article published on 28 December 2020

Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models

scientific article published on 01 May 2021

Nox4 genetic inhibition in experimental hypertension and metabolic syndrome

scientific article

Oligogenic Effects of 16p11.2 Copy-Number Variation on Craniofacial Development

scientific article published on 01 September 2019

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

scientific article

Optimizing PCR for Mouse Genotyping: Recommendations for Reliable, Rapid, Cost Effective, Robust and Adaptable to High-Throughput Genotyping Protocol for Any Type of Mutation

scientific article published on 01 December 2019

PATHBIO: an international training program for precision mouse phenotyping

scientific article published on 22 February 2020

PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-δ activation in mouse models of Down syndrome

scientific article

Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models.

scientific article

Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models

scientific article published on 08 March 2019

Prevalence of sexual dimorphism in mammalian phenotypic traits

scientific article

Prmt2 Regulates the Lipopolysaccharide-Induced Responses in Lungs and Macrophages

article

ProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

scientific article published on 03 December 2021

Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres

scientific article

Proteomic shifts in embryonic stem cells with gene dose modifications suggest the presence of balancer proteins in protein regulatory networks

scientific article

Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse

scientific article

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

scientific article

Rodent models in Down syndrome research: impact and future opportunities.

scientific article

Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs

scientific article published in November 2002

Skin Progenitor Cells Contribute to Bleomycin-Induced Skin Fibrosis

scientific article published on 01 March 2014

Standardized Post-Mortem Examination and Fixation Procedures for Mutant and Treated Mice

scientific article published on 01 March 2011

Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media

scientific article published on 26 September 2013

Synaptic dysfunction in amygdala in intellectual disorder models

scientific article

TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis

scientific article published on 13 May 2019

Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy

scientific article published on 9 April 2014

The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model

scientific article

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity

scientific article

The Deep Genome Project

scientific article published on 03 February 2020

The Human-Specific BOLA2 Duplication Modifies Iron Homeostasis and Anemia Predisposition in Chromosome 16p11.2 Autism Individuals

scientific article published on 24 October 2019

The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord

scientific article

The in vivo Down syndrome genomic library in mouse

scientific article

The mammalian gene function resource: the International Knockout Mouse Consortium

scientific article

The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome

scientific article published on 31 October 2010

Training and aging modulate the loss-of-balance phenotype observed in a new ENU-induced allele of Otopetrin1.

scientific article

Ultrasound-Guided Approaches to Improve Orthotopic Mouse Xenograft Models for Hepatocellular Carcinoma

scientific article published on 30 May 2019

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

scientific article published on 12 October 2017

[Hox genes and genetic control of limb development]

scientific article published on 01 January 1997

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