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List of works by Elizabeth M Simpson

A Novel Mouse Model for Pyridoxine-Dependent Epilepsy Due to Antiquitin Deficiency

scientific article published on 24 September 2020

A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro

article

A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.

scientific article published on 13 December 2005

A regulatory toolbox of MiniPromoters to drive selective expression in the brain

scientific article

Absence of NR2E1 mutations in patients with aniridia.

scientific article

Absence of mutations in NR2E1 and SNX3 in five patients with MMEP (microcephaly, microphthalmia, ectrodactyly, and prognathism) and related phenotypes

scientific article

An essential role for Fas ligand in transplantation tolerance induced by donor bone marrow

scientific article published in March 1998

An interstitial deletion in mouse Y chromosomal DNA created a transcribed Zfy fusion gene

scientific article

B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation

scientific article published on 01 March 1997

Beyond knockouts: cre resources for conditional mutagenesis

scientific article published on 29 August 2012

Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice.

scientific article published in November 2004

Characterization of the murine Zfy1 and Zfy2 promoters

scientific article published in November 1994

Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human

scientific article

Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs

scientific article published in May 1990

Co-activator candidate interactions for orphan nuclear receptor NR2E1.

scientific article

Combined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development

scientific article published on 24 July 2015

Correction: Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials

scientific article published on 01 April 2019

Deletion of the nuclear receptor Nr2e1 impairs synaptic plasticity and dendritic structure in the mouse dentate gyrus

scientific journal article

Engineering embryonic stem cell derived glia for adenosine delivery

scientific article published in November 2004

Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials

scientific article published on 26 September 2018

Expression analysis of novel striatal-enriched genes in Huntington disease

scientific article

Expression of a mouse Zfy-1/lacZ transgene in the somatic cells of the embryonic gonad and germ cells of the adult testis

scientific article published on 01 June 1994

Expression of hygR in transgenic mice causes resistance to toxic effects of hygromycin B in vivo

scientific article published in May 1997

Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent

scientific journal article

Frequencies of cystic fibrosis mutations in the Maine population: high proportion of unknown alleles in individuals of French-Canadian ancestry

article

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

scientific article

Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

scientific article

HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development

scientific article published on 10 October 2017

How do genes that escape from X‐chromosome inactivation contribute to Turner syndrome?

article

Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells

scientific article published on 02 February 2021

Human cis-acting elements regulating escape from X-chromosome inactivation function in mouse

Hyperactivity, startle reactivity and cell-proliferation deficits are resistant to chronic lithium treatment in adult Nr2e1(frc/frc) mice

scientific article

Identification of a set of genes showing regionally enriched expression in the mouse brain

scientific article

Impaired fertility in mice deficient for the testicular germ-cell protease PC4

scientific journal article

Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications

scientific article published on 22 May 2007

Initial association of NR2E1 with bipolar disorder and identification of candidate mutations in bipolar disorder, schizophrenia, and aggression through resequencing

scientific article published in September 2008

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

scientific article published on August 2000

Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness

scientific article published on 26 August 2015

Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family

scientific article published in April 1997

Isolation and characterization of temperature-sensitive RNA polymerase II mutants of Saccharomyces cerevisiae

scientific article published on June 1987

Laboratory Animal Management Assistant (LAMA): a LIMS for active research colonies

scientific article

Linkage mapping of the gene for the LIM-homeoprotein LIM3 (locus Lhx3) to mouse Chromosome 2

article

Metaphase FISHing of transgenic mice recommended: FISH and SKY define BAC-mediated balanced translocation

article

Modelling human regulatory variation in mouse: finding the function in genome-wide association studies and whole-genome sequencing

scientific article

Mouse Y-specific repeats isolated by whole chromosome representational difference analysis

scientific article published in September 1996

Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers

scientific article

Mutation and evolutionary analyses identify NR2E1-candidate-regulatory mutations in humans with severe cortical malformations

scientific article

New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina

scientific article published on 02 October 2018

Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus.

scientific article published on 3 December 2008

Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice

scientific article

Novel Sxr(a) ES cell line offers hope for Y chromosome gene-targeted mice

scientific article published on June 2002

Novel vertebrate genes and putative regulatory elements identified at kidney disease and NR2E1/fierce loci

scientific article

Nr2e1 regulates retinal lamination and the development of Müller glia, S-cones, and glycineric amacrine cells during retinogenesis

scientific article published on 20 June 2015

Of mice and men: will the intersection of social science and genetics create new approaches for intimate partner violence?

scientific article

PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina.

scientific article published on 10 August 2016

Pathological aggression in "fierce" mice corrected by human nuclear receptor 2E1

scientific journal article

Retina restored and brain abnormalities ameliorated by single-copy knock-in of human NR2E1 in null mice

scientific article published on 30 January 2012

Retroposon compensatory mechanism hypothesis not supported: Zfa knockout mice are fertile

scientific article published in September 2003

Revised nomenclature for strain 129 mice

scientific article published in August 1999

SAGE2Splice: unmapped SAGE tags reveal novel splice junctions

scientific article published on 28 April 2006

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

scientific article published in July 2003

Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.

scientific article published on January 2014

Targeting of >1.5 Mb of human DNA into the mouse X chromosome reveals presence of cis-acting regulators of epigenetic silencing

scientific article

The dark phase improves genetic discrimination for some high throughput mouse behavioral phenotyping

scientific article published on June 2004

The mammalian gene function resource: the International Knockout Mouse Consortium

scientific article

The mouse Y chromosome: enrichment, sizing, and cloning by bivariate flow cytometry.

scientific article

The sex-determining region of the human Y chromosome encodes a finger protein.

scientific article

The transcription factor encyclopedia

scientific article (publication date: 2012)

Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP.B to the brain in a mouse model of amyloidosis

scientific article published on 08 October 2021

Transgenic mice for the preparation of puromycin-resistant primary embryonic fibroblast feeder layers for embryonic stem cell selection

scientific article

Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele

article

rAAV-compatible MiniPromoters for restricted expression in the brain and eye.

scientific article published on 10 May 2016

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