List of works - John D. Rioux

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

scientific article

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

scientific article

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

scientific article

Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome

scientific article (publication date: 15 May 1998)

Risk alleles for multiple sclerosis identified by a genomewide study

scientific article (publication date: 30 August 2007)

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

scientific article

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

High-resolution haplotype structure in the human genome

article

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.

scientific article published on 24 September 2006

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

article

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

scientific article

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

scientific article published on September 2008

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

scientific article

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

scientific journal article

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

scientific article

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

scientific article

Defining the role of the MHC in autoimmunity: a review and pooled analysis

scientific article

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

scientific article published on 21 December 2008

Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci

scientific article

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

scientific article

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

scientific article

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

scientific article

LRRK2 is involved in the IFN-gamma response and host response to pathogens

scientific article

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

scientific article

CARD15 genetic variation in a Quebec population: prevalence, genotype-phenotype relationship, and haplotype structure

scientific article published on 17 May 2002

Autoimmune diseases: insights from genome-wide association studies

scientific article published on October 2008

A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms

scientific article

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

scientific article published on 21 October 2009

Genomewide Scan of Multiple Sclerosis in Finnish Multiplex Families

scientific article published on December 1, 1997

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs

scientific article published on 19 February 2004

Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort

scientific article (publication date: May 2006)

A high-density screen for linkage in multiple sclerosis

scientific article

Fine-mapping inflammatory bowel disease loci to single-variant resolution

scientific article

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus

scientific article published on 02 December 2007

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

scientific article

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

scientific journal article

Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height

scientific article

The role of the CD58 locus in multiple sclerosis

scientific article

Identification of two independent risk factors for lupus within the MHC in United Kingdom families

scientific article

List of works by John D. Rioux

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Genetic studies of body mass index yield new insights for obesity biology

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome

Risk alleles for multiple sclerosis identified by a genomewide study

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

High-resolution haplotype structure in the human genome

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

Common variants at five new loci associated with early-onset inflammatory bowel disease

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

Defining the role of the MHC in autoimmunity: a review and pooled analysis

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

LRRK2 is involved in the IFN-gamma response and host response to pathogens

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant

Rare and low-frequency coding variants alter human adult height

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

CARD15 genetic variation in a Quebec population: prevalence, genotype-phenotype relationship, and haplotype structure

Autoimmune diseases: insights from genome-wide association studies

A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

Genomewide Scan of Multiple Sclerosis in Finnish Multiplex Families

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs

Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort

A high-density screen for linkage in multiple sclerosis

Fine-mapping inflammatory bowel disease loci to single-variant resolution

Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Exome-wide association study of plasma lipids in >300,000 individuals

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease

Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height

The role of the CD58 locus in multiple sclerosis

Identification of two independent risk factors for lupus within the MHC in United Kingdom families