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Authors whose works are in public domain in at least one jurisdiction

List of works by Themistocles L Assimes

1-50 of 209 results

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

scientific article published on 18 June 2014

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

scientific article

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

scientific article published on 14 March 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

scientific article

Clinical interpretation and implications of whole-genome sequencing

scientific article published in March 2014

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

DNA methylation-based measures of biological age: meta-analysis predicting time to death

scientific article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

scientific article

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

scientific article

Inactivating mutations in NPC1L1 and protection from coronary heart disease

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

An epigenetic biomarker of aging for lifespan and healthspan

scientific article published on 18 April 2018

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

scientific article

Association analyses based on false discovery rate implicate new loci for coronary artery disease

scientific article published on 17 July 2017

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease

scientific article published on 29 February 2016

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study

scientific article published on 28 April 2008

DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative

scientific article

Age-related somatic structural changes in the nuclear genome of human blood cells

scientific article published on 2 February 2012

Menopause accelerates biological aging

scientific article

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease

scientific article

Genetically determined height and coronary artery disease

scientific article

Call to action: cardiovascular disease in Asian Americans: a science advisory from the American Heart Association

scientific article

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

scientific article

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls

scientific article

A systems biology framework identifies molecular underpinnings of coronary heart disease

scientific article published on 28 March 2013

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

scientific article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

scientific article