List of works by Angus C. Nairn

1H, 15N, and 13C resonance assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000)--a protein inhibitor of protein phosphatase-1.

scientific article published in April 2004

2-Deoxyglucose and NMDA inhibit protein synthesis in neurons and regulate phosphorylation of elongation factor-2 by distinct mechanisms.

scientific article published on 9 January 2006

A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein

scientific article

A Role for Calcineurin (Protein Phosphatase-2B) in the Regulation of Glutamate Release

scientific article published on 01 July 1995

A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth

scientific article

A direct test of the reductionist approach to structural studies of calmodulin activity: relevance of peptide models of target proteins.

scientific article

A mathematical tool for exploring the dynamics of biological networks

scholarly article

A molecular characterization of the choroid plexus and stress-induced gene regulation

scientific article

A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the Ser-Thr phosphatases, PP1 and PP2A.

scientific article published on September 1997

A molecular switch for translational control in taste memory consolidation

scientific article published in November 2005

A multiregional proteomic survey of the postnatal human brain.

scientific article published on 13 November 2017

A network of control mediated by regulator of calcium/calmodulin-dependent signaling

scientific article published in October 2004

A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure

scientific article published in May 2003

A novel cAMP-stimulated pathway in protein phosphatase 2A activation

scientific article

A novel cyclin provides a link between dopamine and RNA processing

scientific article published in October 2001

A phosphatase cascade by which rewarding stimuli control nucleosomal response

scientific article

APP intracellular domain-WAVE1 pathway reduces amyloid-β production

scientific article

ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase).

scientific article published on 6 February 2017

ATP hydrolysis cycles and the gating of CFTR Cl- channels.

scientific article

Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61

scientific article

Activation of a Calcium-Calmodulin-dependent Protein Kinase I Cascade in PC12 Cells

scientific article published in Journal of Biological Chemistry

Activation of exchange protein activated by cAMP in the rat basolateral amygdala impairs reconsolidation of a memory associated with self-administered cocaine

scientific article

Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation step

scientific article

Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines

scientific article

Alzheimer's-like pathology in aging rhesus macaques: Unique opportunity to study the etiology and treatment of Alzheimer's disease

scientific article published on 23 December 2019

Amiloride analogs induce the phosphorylation of elongation factor-2 in vascular endothelial cells

scientific article published on 01 June 1990

Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.

scientific article published in October 1996

An immunocytochemical assay to detect human CFTR expression following gene transfer

scientific article

Angiotensin II Regulates Cardiac Myocyte Protein Synthesis by Activation of Elongation Factor 2

Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes

scientific article published in July 2001

Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue

scientific article published on 01 February 1999

Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase

scientific article

Assessment of cognitive function in the heterozygous reeler mouse

scientific article

Auto-inhibition of Ca(2+)/calmodulin-dependent protein kinase II by its ATP-binding domain.

scientific article

Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals

scientific article

Backbone 1H, 15N, and 13C resonance assignments of ARPP-19

scientific article published on 01 April 2001

Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1

scientific article published on 01 August 2000

Bacterial lipopolysaccharide regulates the phosphorylation of the 68K protein kinase C substrate in macrophages

scientific article published in Journal of Biological Chemistry

Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases

scientific article

CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains

scientific article published on February 2005

CK2 negatively regulates Galphas signaling

scientific article published on 03 August 2009

Ca2+-independent activation of Ca2+/calmodulin-dependent protein kinase II bound to the C-terminal domain of CaV2.1 calcium channels

scientific article published on 19 December 2012

Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmission.

scientific article published on October 1998

Ca2+/calmodulin-dependent protein kinase V and I may form a family of isoforms

scientific article

CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology

scientific article published on August 2008

Calcium-binding proteins and the regulation of contractile activity

scientific article

Calcium-dependent regulation of protein synthesis.

scientific article

Calcium-induced synergistic inhibition of a translational factor eEF2 in nerve growth cones

scientific article published on 13 December 2006

Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes

scientific article published on February 1990

Calcium/calmodulin-dependent protein kinases

scientific article published on August 1994

Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase ⬇️

scientific article published on December 1, 1984

Calmodulin and myosin light-chain kinase of rabbit fast skeletal muscle

scientific article published on April 1979

Calmodulin and protein kinase C cross-talk: the MARCKS protein is an actin filament and plasma membrane cross-linking protein regulated by protein kinase C phosphorylation and by calmodulin

scientific article published on January 1, 1992

Cardiac chloride channels: incremental regulation by phosphorylation/dephosphorylation

scientific article published in December 1993

Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations

scientific article

Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein

scientific article

Cell-Type-Specific Proteomics: A Neuroscience Perspective

scholarly article by Rashaun S Wilson & Angus C. Nairn published 9 December 2018 in Proteomes

Cellular localization of calmodulin-dependent protein kinases I and II to A-cells and D-cells of the endocrine pancreas

scientific article published in April 1998

Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit

scientific article published on June 2000

Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice.

scientific article

Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.

scientific article

Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine

scientific article published on December 31, 1992

Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymes

scientific article published on January 1997

Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line ⬇️

scientific article published on March 15, 1992

Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2.

scientific article

Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins

scientific article

Characterization of the mechanism of regulation of Ca2+/ calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase

scientific article

Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels

scientific article

Cocaine regulates MEF2 to control synaptic and behavioral plasticity

scientific article

Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.

scientific article published in March 2006

Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens

scholarly article

Contrasting features of ERK1/2 activity and synapsin I phosphorylation at the ERK1/2-dependent site in the rat brain in status epilepticus induced by kainic acid in vivo

scientific article

Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.

scientific article

Control of the CFTR channel's gates

scientific article published on November 2005

Correction: Substrate-Based Fragment Identification for the Development ofSelective, Nonpeptidic Inhibitors of Striatal-Enriched Protein TyrosinePhosphatase.

scientific article published on 12 December 2014

Correlation between protein kinase C binding proteins and substrates in REF52 cells.

scientific article published on May 1994

Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle

scientific article published in March 1994

Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II

scientific article (publication date: May 2003)

Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity

scientific article published in May 2001

Cyclic GMP-dependent protein phosphorylation in mammalian brain.

scientific article published in November 1983

Cyclic Nucleotide-Dependent Protein Kinases and Some Major Substrates in the Rat Cerebellum After Neonatal X-Irradiation

scientific article published on 01 February 1983

Cystic fibrosis transmembrane conductance regulator is found within brain ventricular epithelium and choroid plexus

scientific article published on 01 April 1995

Cytoplasmic localization of calcium/calmodulin-dependent protein kinase I-alpha depends on a nuclear export signal in its regulatory domain

scientific article published in May 2004

D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex

scientific article

DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons

scientific article

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons

scientific article

DARPP-32 mediates the actions of multiple drugs of abuse

scientific article

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1

scientific article

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus

scientific article published in January 1984

DARPP-32: an integrator of neurotransmission

scientific article published on January 2004

Decoding neuroproteomics: integrating the genome, translatome and functional anatomy

scientific article published on 28 October 2014

Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease.

scientific article

Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons

scientific article published on February 1998

Detailed structural characterization of unbound protein phosphatase 1 inhibitors

scientific article

Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF.

scientific article published on 24 April 2015

Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD)

scientific article published on 02 April 2019

Development of a highly automated and multiplexed targeted proteome pipeline and assay for 112 rat brain synaptic proteins

scientific article published on 12 February 2015

Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency

scientific article published on October 1996

Differential Protein Expression in Striatal D1- and D2-Dopamine Receptor-Expressing Medium Spiny Neurons

scientific article published on 13 October 2020

Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver

scientific article

Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons

scientific article published on 20 May 2013

Differential localization of protein phosphatase-1alpha, beta and gamma1 isoforms in primate prefrontal cortex

scientific article published on 09 March 2005

Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons

scientific article

Direct Interaction of PP2A Phosphatase with GABAB Receptors Alters Functional Signaling

scientific article published on 28 February 2020

Discovery of protein phosphatase 2C inhibitors by virtual screening

scientific article published on March 2006

Disruption of reelin signaling attenuates methamphetamine-induced hyperlocomotion

scientific article

Distinct Mg(2+)-dependent steps rate limit opening and closing of a single CFTR Cl(-) channel

scientific article

Distinguishing among protein kinases by substrate specificities

scientific article published on 01 July 1987

Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.

scientific article published on September 1992

Dopamine-dependent tuning of striatal inhibitory synaptogenesis.

scientific article published on February 2010

Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels

scientific article published on 28 August 2015

Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia

scientific article published on July 2000

Dual involvement of G-substrate in motor learning revealed by gene deletion.

scientific article

Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control

scientific article published on 25 October 2006

Editorial for Special Issue: Neuroproteomics

scientific article published on 31 May 2019

Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice

scientific article

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

scientific article

Elevated glucose activates protein synthesis in cultured cardiac myocytes

scientific article

Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons

scientific article published in September 1991

Evaluation of the Phosphoproteome of Mouse Alpha 4/Beta 2-Containing Nicotinic Acetylcholine Receptors In Vitro and In Vivo

article

Evidence for isoproterenol-induced phosphorylation of phosphatase inhibitor-1 in the intact heart

scientific article published on December 1991

Evidence for the involvement of Lfc and Tctex-1 in axon formation

scientific article

Expression of PKC substrate proteins, GAP-43 and neurogranin, is downregulated by cAMP signaling and alterations in synaptic activity

scientific article published on 14 November 2007

FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity

scientific article

Faculty of 1000 evaluation for Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes

article published in 2015

Flexibility in the PP1:spinophilin holoenzyme

scientific article

Folding of Intrinsically Disordered Protein Phosphatase 1 Regulatory Proteins

scientific article

Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.

scientific article

Functional genomic and proteomic analysis reveals disruption of myelin-related genes and translation in a mouse model of early life neglect

scientific article

Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain

scientific article

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model

scientific article

Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells

scientific article published on 18 March 2003

Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution

scientific article

Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades

scientific article

Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons.

scientific article published on May 1997

Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases

scientific article published on 6 December 2017

Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator

scientific article published in November 1991

Identification of the Ca2+-dependent modulator protein as the fourth subunit of rabbit skeletal muscle phosphorylase kinase ⬇️

scientific article published on August 15, 1978

Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM.

scientific article

Immunochemical localization of calcium/calmodulin-dependent protein kinase I.

scientific article published in May 1995

Immunocytochemical localization of phosphatase inhibitor-1 in rat brain

scientific article published on August 1991

In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer

scientific article published on 12 October 2006

Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling

scientific article

Increased phosphorylation of elongation factor 2 in Alzheimer's disease

scientific article published in October 1992

Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation ⬇️

scientific article published on June 1, 1984

Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.

scientific article

Inhibition of Tumor Necrosis Factor Signal Transduction in Endothelial Cells by Dimethylaminopurine

scientific article published in Journal of Biological Chemistry

Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinase

scientific article (publication date: 9 April 1999)

Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice

scientific article

Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia

scientific article published on 01 December 1982

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease

scientific article (publication date: August 2014)

Insulin rapidly induces the biosynthesis of elongation factor 2.

scientific article published on July 1989

Intracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortex

scientific article published in October 1986

Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia ⬇️

scientific article published on December 1, 1980

Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine

scientific article published in August 2002

Isoform-Level Interpretation of High-Throughput Proteomics Data Enabled by Deep Integration with RNA-seq

article

Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II.

scientific article published on November 1995

Localization in mammalian brain of G-substrate, a specific substrate for guanosine 3',5'-cyclic monophosphate-dependent protein kinase

scientific article published in November 1984

Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells

scientific article published in December 1993

Luteinizing hormone receptor activation in ovarian granulosa cells promotes protein kinase A-dependent dephosphorylation of microtubule-associated protein 2D.

scientific article published on 8 May 2008

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin

scientific article published on April 16, 1992

Making brain proteomics true to type

scientific article

Mammalian brain phosphoproteins as substrates for calcineurin

scientific journal article

Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase ⬇️

scientific article (publication date: 15 January 1992)

Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides

scientific article published on January 1995

Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors

scientific article published on 9 September 2002

Mechanisms for increased levels of phosphorylation of elongation factor-2 during hibernation in ground squirrels

scientific article

Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling

scientific article

Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens

scientific article

Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture ⬇️

scientific article published on December 1, 1980

Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylation

scientific article

Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation

scientific journal article

Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons

scientific article published on 01 February 1995

Molecular characterization of recombinant mouse adenosine kinase and evaluation as a target for protein phosphorylation

scientific article

Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex

scientific article

Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity

scientific article published on 29 December 2016

Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms

scientific article published in January 1989

Mutation of the Protein Kinase C Phosphorylation Site on Rat α1 Na+,K+-ATPase Alters Regulation of Intracellular Na+and pH and Influences Cell Shape and Adhesiveness

scientific article published in Journal of Biological Chemistry

N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability properties

scientific article published in January 2002

N-methyl-D-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: a role for N-methyl-D-aspartate receptors in controlling protein synthesis.

scientific article published on December 1997

NMDA receptor-mediated control of protein synthesis at developing synapses.

scientific article published in March 2000

Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells

scientific article published in October 1987

Nerve growth factor-induced down-regulation of calmodulin-dependent protein kinase III in PC12 cells involves cyclic AMP-dependent protein kinase

scientific article published on March 1990

Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons

scientific article published on 22 July 2005

Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor-2 kinase

scientific article published on July 2000

Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.

scientific article published in February 2006

On the mechanism of MgATP-dependent gating of CFTR Cl- channels

scientific article

Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.

scientific article

Orbitofrontal cortex and cognitive-motivational impairments in psychostimulant addiction: evidence from experiments in the non-human primate

scientific article published on 14 August 2007

PCPP-260, a Purkinje cell-specific cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.

scientific article published in April 1986

PKC-alpha regulates cardiac contractility and propensity toward heart failure

scientific journal article

PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation

scientific article

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation

scientific article published on 26 April 2009

PP1gamma2 and PPP1R11 are parts of a multimeric complex in developing testicular germ cells in which their steady state levels are reciprocally related

scientific article

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

scientific article

Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex

scientific article

Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation

scientific article published on July 2016

Phosphoproteomic Analysis of the Amygdala Response to Adolescent Glucocorticoid Exposure Reveals G-Protein Coupled Receptor Kinase 2 as a Target for Reducing Motivation for Alcohol

scientific article published in 2018

Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells ⬇️

scientific article published on April 1, 1991

Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium.

scientific article published on August 1996

Phosphorylation of ARPP19 by protein kinase A prevents meiosis resumption in Xenopus oocytes

scientific article

Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C.

scientific article published in June 1992

Phosphorylation of Alzheimer beta-amyloid precursor-like proteins

scientific article

Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo

scientific article published in January 2007

Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action

scientific article

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

scientific article

Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.

scientific article published on 9 September 2006

Phosphorylation of DARPP-32, a Dopamine- and cAMP-regulated Phosphoprotein, by Casein Kinase Iin Vitroandin Vivo

scientific article published in Journal of Biological Chemistry

Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1.

scientific article published in November 2017

Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology

scholarly article

Phosphorylation of connexin 32, a hepatocyte gap-junction protein, by cAMP-dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II.

scientific article published on September 1990

Phosphorylation of connexin43 and the regulation of neonatal rat cardiac myocyte gap junctions

scientific article published on August 1997

Phosphorylation of elongation factor 2 in normal and malignant rat glial cells

scientific article

Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo

scientific article published in November 2017

Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C.

scientific article

Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).

scientific article

Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.

scientific article

Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme

scientific article published on December 1991

Phosphorylation of the cystic fibrosis transmembrane conductance regulator ⬇️

scientific article published on June 25, 1992

Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase

scientific article

Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6

scientific article (publication date: 15 April 1999)

Population density functions: a differential equation approach

scientific article published on February 1988

Postsynaptic modulation of synaptic efficacy at mixed synapses on the Mauthner cell

scientific article

Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.

scientific article

Preparation and characterization of recombinant protein phosphatase 1.

scientific article published on January 2003

Prior chronic cocaine exposure in mice induces persistent alterations in cognitive function

scientific article

Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating ⬇️

scientific article

Prostaglandin E(2) interaction with AVP: effects on AQP2 phosphorylation and distribution

scientific article published on 01 March 2000

Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase

scientific article published on 02 May 2013

Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor

scientific article

Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit

scholarly article

Protein kinase C substrate and inhibitor characteristics of peptides derived from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domain

scientific article published on August 1991

Protein kinase C-dependent dephosphorylation of tyrosine hydroxylase requires the B56δ heterotrimeric form of protein phosphatase 2A

scientific article

Protein kinase inhibitors selectively block phorbol ester- or forskolin-induced changes in excitability of Aplysia neurons.

scientific article published on February 1989

Protein kinases 1988: a current perspective

scientific article

Protein kinases and phosphoproteins in the nervous system

scientific article

Protein kinases in the brain

scientific article published on January 1985

Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin

scientific article

Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3

scientific article

Protein phosphatases and Alzheimer's disease

scientific article

Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein

scientific article

Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.

scientific article

Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19.

scientific article

Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.

scientific article

Purification and characterization of calmodulin-dependent protein kinase III from rabbit reticulocytes and rat pancreas

scientific article

Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport

scientific article

Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry

scientific article

Recent advances in neuroproteomics

scientific article

Recent advances in neuroproteomics and potential application to studies of drug addiction

scientific article

Recent advances in quantitative neuroproteomics

scientific article

Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition

scientific article

Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization

scientific article

Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems

Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems

Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane

scientific article published in May 1991

Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists

scientific article published in November 2003

Regulation of CFTR Cl- ion channels by phosphorylation and dephosphorylation.

scientific article

Regulation of CFTR channel gating

scientific article

Regulation of CFTR channel gating

scientific article published on 01 November 1994

Regulation of ERK1/2 mitogen-activated protein kinase by NMDA-receptor-induced seizure activity in cortical slices

scientific article published on 16 February 2013

Regulation of NMDA receptor trafficking by amyloid-beta

scientific journal article

Regulation of Na+, K+-ATPase isoforms in rat neostriatum by dopamine and protein kinase C.

scientific article

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

scientific article

Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons

scientific article

Regulation of chloride channels by protein kinase C in normal and cystic fibrosis airway epithelia

scientific article published in Science

Regulation of neurite outgrowth mediated by localized phosphorylation of protein translational factor eEF2 in growth cones

scientific article published on 26 November 2012

Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo

scientific article published on 01 June 2000

Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.

scientific article

Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade

scientific article published on 01 February 1998

Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways

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Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses

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Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis

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Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases

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Regulator of calmodulin signaling knockout mice display anxiety-like behavior and motivational deficits

scientific article published on January 2012

Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation

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Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol

scientific article published in April 2004

Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis

scientific article published on November 2006

Role of Ca2+/calmodulin-dependent protein phosphorylation in signal transduction.

scientific article published on January 1990

Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.

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Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function

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Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons

scientific article published in May 1999

Role of elongation factor 2 in regulating peptide-chain elongation in the heart

scientific article published on 01 April 1994

Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation.

scientific article published in June 1999

Role of protein phosphorylation in neuronal signal transduction

scientific article

STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease

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Selective ablation of Ppp1cc gene in testicular germ cells causes oligo-teratozoospermia and infertility in mice

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Selective knockout of the casein kinase 2 in d1 medium spiny neurons controls dopaminergic function

scientific article published on 3 January 2013

Serine/threonine protein phosphatase assays

scientific article published on October 2010

Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein

scientific article

Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains

scientific article

Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization

scientific article

Skeletal muscle sarcolemma proteins as targets for adenosine 3′:5′-monophosphate-dependent and calcium-dependent protein kinases

article

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

scientific article

Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin

scientific article published in July 2004

Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology

journal article published in 2008

Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.

scientific article

Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons.

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Structural Domains Involved in the Regulation of Transmitter Release by Synapsins

scientific article published on 01 March 2005

Structural basis for protein phosphatase 1 regulation and specificity

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Structural basis for spinophilin-neurabin receptor interaction

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Structural characterization of the neurabin sterile alpha motif domain

scientific article published on 01 October 2007

Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme

scientific article

Structure, Regulation, and Function of Calcium/Calmodulin-Dependent Protein Kinase I

scientific article published on 01 January 1996

Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation

scientific article published on June 2008

Subcellular localization of CFTR to endosomes in a ductal epithelium ⬇️

scientific article published on August 1, 1994

Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase

scientific article

Synaptic NMDA Receptor Activation Induces Ubiquitination and Degradation of STEP61.

scientific article published on 2 May 2017

Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5

scientific article

Synaptic plasticity: one STEP at a time

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Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP.

scientific article

Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity

scientific article published on November 1990

TARPP, a novel protein that accompanies TCR gene rearrangement and thymocyte education

scientific article published in April 2001

THE RELATIONSHIP OF THE STRUCTURE TO THE FUNCTION OF CALMODULIN IN THE MYOSIN LIGHT CHAIN KINASE SYSTEM

scientific article published on 01 January 1980

TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation

article

The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.

scholarly article

The DARPP-32/protein phosphatase-1 cascade: a model for signal integration1Published on the World Wide Web on 22 January 1998.1

article

The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway.

scientific article published in August 2000

The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons

scientific article

The PsychENCODE project

scientific article

The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.

scientific article published on 21 March 2018

The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines

scientific article

The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology.

scientific article

The amino acid sequence of rabbit skeletal muscle calmodulin

scientific article published on 01 February 1984

The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).

scientific article published in February 2002

The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins

scientific article published on 01 June 1987

The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.

scientific article published on February 1997

The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity

scientific article published on March 1999

The dominant protein phosphatase PP1c isoform in smooth muscle cells, PP1cβ, is essential for smooth muscle contraction

scientific article published in Journal of Biological Chemistry

The equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver

scientific article

The expression of Ca2+/calmodulin-dependent protein kinase I in rat retina is regulated by light stimulation.

scientific article published in September 1999

The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein-coupled receptor signaling in platelets

scientific article published on 14 June 2017

The phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes

scientific article published on 18 June 2013

The preparation of calmodulins from barley (Hordeum sp.) and basidiomycete fungi

scientific article published on March 1980

The protein kinase A-regulated cardiac Cl- channel resembles the cystic fibrosis transmembrane conductance regulator

scientific article published on November 5, 1992

The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action.

scientific article

The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains

scientific article

The role of DARPP-32 in the actions of drugs of abuse

scientific article published in January 2004

The role of calmodulin in the myosin light-chain kinase system [proceedings]

scientific article published on October 1979

The role of calmodulin in the structure and regulation of phosphorylase kinase from rabbit skeletal muscle

scientific article

The role of protein phosphatases in synaptic transmission, plasticity and neuronal development

scientific article published on June 1, 1992

The role of ventral striatal cAMP signaling in stress-induced behaviors

scientific article

The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity

scientific article published in May 2003

Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle

scientific article

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1 ⬇️

scientific article published on August 31, 1995

Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity

scientific article

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code

scientific article

Variability of distribution of Ca(2+)/calmodulin-dependent kinase II at mixed synapses on the mauthner cell: colocalization and association with connexin 35

scientific article

WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines

scholarly article

WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine

scientific article published on 23 January 2017

Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice

scientific article published on May 1997

Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner

scientific article published on 03 August 2009

X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors

scientific article published on 8 November 2017

YPED: an integrated bioinformatics suite and database for mass spectrometry-based proteomics research

scientific article published on 21 February 2015

Zinc inhibits protein synthesis in neurons. Potential role of phosphorylation of translation initiation factor-2alpha

scientific article published on November 1999

Zinc-induced inhibition of protein synthesis and reduction of connexin-43 expression and intercellular communication in mouse cortical astrocytes

scientific article published in September 2002

[23] Production of phosphorylation state-specific antibodies

article

cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex

scientific article published on 18 March 2014

cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3.

scientific article

cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones

scientific article published in October 1986

cGMP-dependent protein kinase in dorsal root ganglion: relationship with nitric oxide synthase and nociceptive neurons

scientific article

cGMP-dependent protein kinase regulation of a chloride channel in T84 cells

scientific article published on May 1, 1992

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