List of works - Sebastian Hiller

4D APSY-HBCB(CG)CDHD experiment for automated assignment of aromatic amino acid side chains in proteins

article

4D solid-state NMR for protein structure determination

scientific article

A Spring-Loaded Mechanism Governs the Clamp-like Dynamics of the Skp Chaperone

scientific article published on 10 June 2017

A guide to quantifying membrane protein dynamics in lipids and other native-like environments by solution-state NMR spectroscopy

scholarly article by Stefan Bibow published in September 2018

A molecular mechanism of chaperone-client recognition.

scientific article

A proton-detected 4D solid-state NMR experiment for protein structure determination

scientific article

APSY-NMR with proteins: practical aspects and backbone assignment

scientific article published on 8 October 2008

ASC filament formation serves as a signal amplification mechanism for inflammasomes

scientific article published on 22 June 2016

Automated NMR assignment of protein side chain resonances using automated projection spectroscopy (APSY).

scientific article published on 19 August 2008

Automated NMR resonance assignment of large proteins for protein-ligand interaction studies.

scientific article published on 16 December 2010

Automated projection spectroscopy (APSY).

scientific article

Automated projection spectroscopy and its applications

scientific article published on January 2012

Automated resonance assignment of proteins: 6D APSY-NMR.

scientific article

Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1

scientific article

Bacterial origin of a mitochondrial outer membrane protein translocase: new perspectives from comparative single channel electrophysiology

scientific article

Cell-free protein synthesis of perdeuterated proteins for NMR studies.

scientific article published on 11 September 2007

Chaperone-Bound Clients: The Importance of Being Dynamic

scientific article published on 02 January 2019

Chaperone–client complexes: A dynamic liaison

scientific article published on 01 April 2018

Characterization of the insertase BamA in three different membrane mimetics by solution NMR spectroscopy

scientific article

Common Patterns in Chaperone Interactions with a Native Client Protein

scholarly article by Lichun He et al published 14 May 2018 in Angewandte Chemie

Conformation and dynamics of the periplasmic membrane-protein-chaperone complexes OmpX-Skp and tOmpA-Skp.

scientific article

Conformational plasticity of molecular chaperones involved in periplasmic and outer membrane protein folding

article by Guillaume Mas & Sebastian Hiller published 17 May 2018 in FEMS Microbiology Letters

Conserved Omp85 lid-lock structure and substrate recognition in FhaC

scientific article

Coupled decomposition of four-dimensional NOESY spectra

scientific article published on September 2009

Dynamic nature of heterochromatin highlighted by a HP1Swi6-dependent gene silencing mechanism

scientific article published on 3 October 2012

Frustrated Interfaces Facilitate Dynamic Interactions between Native Client Proteins and Holdase Chaperones

scientific article published on 17 September 2019

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

scientific article

Gasdermin-A3 pore formation propagates along variable pathways

scientific article published on 11 May 2022

HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts

scientific article published on 7 June 2012

Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation

scientific article published on 27 December 2019

Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach

scientific article published on 09 May 2019

Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis

scientific article published on 15 January 2021

Interactions with hydrophobic clusters in the urea-unfolded membrane protein OmpX.

scientific article published in January 2008

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification

scientific article published on 19 January 2016

Lipid- and cholesterol-mediated timescale-specific modulation of the outer membrane protein X dynamics in lipid bilayers

scientific article published on 23 October 2018

Managing the solvent water polarization to obtain improved NMR spectra of large molecular structures

scientific article

Mechanism of membrane pore formation by human gasdermin-D

scientific article published on 13 June 2018

Molecular chaperones and their denaturing effect on client proteins

scientific article published on 02 November 2020

Monitoring Backbone Hydrogen-Bond Formation in β-Barrel Membrane Protein Folding

scientific article published on 9 April 2016

Monitoring Backbone Hydrogen-Bond Formation in β-Barrel Membrane Protein Folding

NMR assignment of the E. coli type 1 pilus protein FimF

scientific article published on 07 April 2007

NMR pseudocontact shifts in a symmetric protein homotrimer

scientific article published on 03 July 2020

NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain

scientific article

Nonmicellar systems for solution NMR spectroscopy of membrane proteins

scientific article

Nonrandom structure in the urea-unfolded Escherichia coli outer membrane protein X (OmpX).

scientific article published in February 2004

PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains

scientific article

Perspectives of solution NMR spectroscopy for structural and functional studies of integral membrane proteins

Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter

scientific article published on 10 February 2020

Purification and Bicelle Crystallization for Structure Determination of the E. coli Outer Membrane Protein TamA.

scientific article

Reciprocal growth control by competitive binding of nucleotide second messengers to a metabolic switch in Caulobacter crescentus

scientific article published on 09 November 2020

Regulation of chaperone function by coupled folding and oligomerization

scientific article published on 21 October 2020

Residual structure in a peptide fragment of the outer membrane protein X under denaturing conditions: a molecular dynamics study

scientific article published on 21 March 2010

Revisiting the interaction between the chaperone Skp and lipopolysaccharide

scientific article

Sequence-Specific Solution NMR Assignments of the β-Barrel Insertase BamA to Monitor Its Conformational Ensemble at the Atomic Level

scholarly article by Jean-Baptiste Hartmann et al published 20 August 2018 in Journal of the American Chemical Society

Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR spectroscopy

scientific article published on 11 August 2007

Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth.

scientific article

Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs

scientific article published on 15 November 2011

Solution NMR studies of membrane-protein-chaperone complexes.

scientific article published in January 2012

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

scientific article

Structural Mapping of a Chaperone-Substrate Interaction Surface

Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs

scientific article published on December 2009

Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.

scientific article

Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis

scientific article published on 04 May 2020

The 3D structures of VDAC represent a native conformation

scientific article

The Structural Basis for Low Conductance in the Membrane Protein VDAC upon β-NADH Binding and Voltage Gating

scientific article published on 17 December 2019

The T-lock: automated compensation of radio-frequency induced sample heating

scientific article

The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase

The dynamic dimer structure of the chaperone Trigger Factor

scientific article published on 8 December 2017

The functional heart of the M2 channel

scientific article

The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins

scientific article

The structural basis of autotransporter translocation by TamA

scientific article

Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance.

scientific article

Two-State Folding of the Outer Membrane Protein X into a Lipid Bilayer Membrane

scientific article published on 29 January 2019

List of works by Sebastian Hiller

4D APSY-HBCB(CG)CDHD experiment for automated assignment of aromatic amino acid side chains in proteins

4D solid-state NMR for protein structure determination

A Spring-Loaded Mechanism Governs the Clamp-like Dynamics of the Skp Chaperone

A guide to quantifying membrane protein dynamics in lipids and other native-like environments by solution-state NMR spectroscopy

A molecular mechanism of chaperone-client recognition.

A proton-detected 4D solid-state NMR experiment for protein structure determination

APSY-NMR with proteins: practical aspects and backbone assignment

ASC filament formation serves as a signal amplification mechanism for inflammasomes

Automated NMR assignment of protein side chain resonances using automated projection spectroscopy (APSY).

Automated NMR resonance assignment of large proteins for protein-ligand interaction studies.

Automated projection spectroscopy (APSY).

Automated projection spectroscopy and its applications

Automated resonance assignment of proteins: 6D APSY-NMR.

Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1

Bacterial origin of a mitochondrial outer membrane protein translocase: new perspectives from comparative single channel electrophysiology

Cell-free protein synthesis of perdeuterated proteins for NMR studies.

Chaperone-Bound Clients: The Importance of Being Dynamic

Chaperone–client complexes: A dynamic liaison

Characterization of the insertase BamA in three different membrane mimetics by solution NMR spectroscopy

Common Patterns in Chaperone Interactions with a Native Client Protein

Conformation and dynamics of the periplasmic membrane-protein-chaperone complexes OmpX-Skp and tOmpA-Skp.

Conformational plasticity of molecular chaperones involved in periplasmic and outer membrane protein folding

Conserved Omp85 lid-lock structure and substrate recognition in FhaC

Coupled decomposition of four-dimensional NOESY spectra

Dynamic nature of heterochromatin highlighted by a HP1Swi6-dependent gene silencing mechanism

Frustrated Interfaces Facilitate Dynamic Interactions between Native Client Proteins and Holdase Chaperones

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Gasdermin-A3 pore formation propagates along variable pathways

HP1(Swi6) mediates the recognition and destruction of heterochromatic RNA transcripts

Hybrid histidine kinase activation by cyclic di-GMP-mediated domain liberation

Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach

Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis

Interactions with hydrophobic clusters in the urea-unfolded membrane protein OmpX.

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification

Lipid- and cholesterol-mediated timescale-specific modulation of the outer membrane protein X dynamics in lipid bilayers

Managing the solvent water polarization to obtain improved NMR spectra of large molecular structures

Mechanism of membrane pore formation by human gasdermin-D

Molecular chaperones and their denaturing effect on client proteins

Monitoring Backbone Hydrogen-Bond Formation in β-Barrel Membrane Protein Folding

Monitoring Backbone Hydrogen-Bond Formation in β-Barrel Membrane Protein Folding

NMR assignment of the E. coli type 1 pilus protein FimF

NMR pseudocontact shifts in a symmetric protein homotrimer

NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain

Nonmicellar systems for solution NMR spectroscopy of membrane proteins

Nonrandom structure in the urea-unfolded Escherichia coli outer membrane protein X (OmpX).

PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains

Perspectives of solution NMR spectroscopy for structural and functional studies of integral membrane proteins

Precise timing of transcription by c-di-GMP coordinates cell cycle and morphogenesis in Caulobacter

Purification and Bicelle Crystallization for Structure Determination of the E. coli Outer Membrane Protein TamA.

Reciprocal growth control by competitive binding of nucleotide second messengers to a metabolic switch in Caulobacter crescentus

Regulation of chaperone function by coupled folding and oligomerization

Residual structure in a peptide fragment of the outer membrane protein X under denaturing conditions: a molecular dynamics study

Revisiting the interaction between the chaperone Skp and lipopolysaccharide

Sequence-Specific Solution NMR Assignments of the β-Barrel Insertase BamA to Monitor Its Conformational Ensemble at the Atomic Level

Sequence-specific resonance assignment of soluble nonglobular proteins by 7D APSY-NMR spectroscopy

Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth.

Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs

Solution NMR studies of membrane-protein-chaperone complexes.

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

Structural Mapping of a Chaperone-Substrate Interaction Surface

Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs

Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.

Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis

The 3D structures of VDAC represent a native conformation

The Structural Basis for Low Conductance in the Membrane Protein VDAC upon β-NADH Binding and Voltage Gating

The T-lock: automated compensation of radio-frequency induced sample heating

The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase

The dynamic dimer structure of the chaperone Trigger Factor

The functional heart of the M2 channel

The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins

The structural basis of autotransporter translocation by TamA

Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance.

Two-State Folding of the Outer Membrane Protein X into a Lipid Bilayer Membrane

Übereinstimmende Muster in Chaperon-Interaktionen mit einem nativen Klientenprotein