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List of works by Asier Sáez-Cirión

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Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study

scientific article
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype

scholarly article
International AIDS Society global scientific strategy: towards an HIV cure 2016.

scientific article published on 11 July 2016
Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

scientific article published on 23 April 2009
Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses

scientific article
Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers

scientific article
Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring.

scientific article
HIV cure research: advances and prospects

scientific article
Replication-competent HIV strains infect HIV controllers despite undetectable viremia (ANRS EP36 study)

article
p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway

scientific article published on 30 September 2013
HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case report

scientific article published on 9 December 2015
HIV controllers: how do they tame the virus?

scientific article published on 5 November 2007
The pre-transmembrane region of the human immunodeficiency virus type-1 glycoprotein: a novel fusogenic sequence

scientific article published in July 2000
Elevated IP10 levels are associated with immune activation and low CD4+ T-cell counts in HIV controller patients

article
High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers

scientific article
Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission

scientific article
Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission.

scientific article published on 03 January 2008
Ex vivo T cell–based HIV suppression assay to evaluate HIV-specific CD8+ T-cell responses

article
HIV controllers: a genetically determined or inducible phenotype?

scientific article published on July 2013
Pre-transmembrane sequence of Ebola glycoprotein. Interfacial hydrophobicity distribution and interaction with membranes.

scientific article published on January 2003
Both HLA-B*57 and plasma HIV RNA levels contribute to the HIV-specific CD8+ T cell response in HIV controllers

scientific article published on 16 October 2013
Conformational transitions of membrane-bound HIV-1 fusion peptide

scientific article published in August 2002
Potential role for HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppression and cytotoxicity in HIV controllers

scientific article
Long-Term Spontaneous Control of HIV-1 Is Related to Low Frequency of Infected Cells and Inefficient Viral Reactivation

scientific article published on 27 April 2016
Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents

scientific article published on 11 January 2017
Immunologic and Virologic Progression in HIV Controllers: The Role of Viral "Blips" and Immune Activation in the ANRS CO21 CODEX Study.

scientific article published on 6 July 2015
Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset

scientific article
Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection

scientific article published on 20 December 2018
Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration

scientific article published on 17 January 2014
Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks

scientific article
Natural resistance to HIV infection: lessons learned from HIV‐exposed uninfected individuals.

scientific article published in November 2010
Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses

scientific article
Antibodies attenuate the capacity of dendritic cells to stimulate HIV-specific cytotoxic T lymphocytes

scientific article published on 11 October 2012
Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?

scientific article
p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity

scientific article published on 20 September 2017
High eomesodermin expression among CD57+ CD8+ T cells identifies a CD8+ T cell subset associated with viral control during chronic human immunodeficiency virus infection

scientific article published on 6 August 2014
Quantitative real-time analysis of HIV-1 gene expression dynamics in single living primary cells

scientific article published in June 2006
Reply to Pauls et al.: p21 is a master regulator of HIV replication in macrophages through dNTP synthesis block

scientific article published on April 2014
Ku80 participates in the targeting of retroviral transgenes to the chromatin of CHO cells.

scientific article published on 16 May 2007
Polyfunctional HIV-specific T cells in Post-Treatment Controllers

scientific article
Posttreatment controllers: what do they tell us?

scientific article
Immune Responses to Retroviruses.

scientific article published on 12 January 2018
Immunodominance of HLA-B27-restricted HIV KK10-specific CD8(+) T-cells is not related to naïve precursor frequency

scientific article published on 13 October 2012
Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers.

scientific article
HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

scientific article published on 6 September 2017
Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion

scientific article published in March 2013
Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles

scientific article
Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection

scientific article published on 12 July 2019
The hydrophobic internal region of bovine prion protein shares structural and functional properties with HIV type 1 fusion peptide

scientific article
Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells.

scientific article

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