List of works - Eric R. Gamazon

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

scientific article

Obesity-associated variants within FTO form long-range functional connections with IRX3

scientific article (publication date: 20 March 2014)

A gene-based association method for mapping traits using reference transcriptome data

scientific article

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

SCAN: SNP and copy number annotation

scientific article

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue

scientific article

Genome-wide association study of obsessive-compulsive disorder.

scientific article

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

scientific article published on 05 June 2013

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

scientific article published in October 2013

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.

scientific article published on 3 January 2012

Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci

scientific article

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

article

Genome-wide association study of Tourette's syndrome

scientific article

Population differences in microRNA expression and biological implications

scientific article published on July 1, 2011

The missing association: sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans

scientific article published on 26 January 2011

Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals

scientific journal article

Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis

scientific article published on 28 June 2013

Genetic architecture of microRNA expression: implications for the transcriptome and complex traits

scientific article

Campylobacter jejuni type VI secretion system: roles in adaptation to deoxycholic acid, host cell adherence, invasion, and in vivo colonization

scientific article

Exprtarget: an integrative approach to predicting human microRNA targets

scientific article

Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients

scientific article

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

scientific article published on 4 May 2017

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

scientific article

Genomics of alternative splicing: evolution, development and pathophysiology

scientific article published on January 1, 2014

Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait

scientific article

A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci

scientific article

On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy

scientific article

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

scientific article

Variants affecting exon skipping contribute to complex traits.

scientific article

Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death

scientific article

Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs

scientific article

Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

scientific article

The impact of human copy number variation on gene expression: Figure 1

scientific article published on April 27, 2015

Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans

scientific article

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy

scientific article published on 30 November 2012

Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.

scientific article

PACdb: a database for cell-based pharmacogenomics

scientific article published on April 2010

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations

scientific article

Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers

scientific article

Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients

scientific article published on 28 March 2013

Poly-omic prediction of complex traits: OmicKriging

scientific article

Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci

scientific article

Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases

scientific article (publication date: 2013)

Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver

scientific article

A genome-wide integrative study of microRNAs in human liver

scientific article

Linking the genetic architecture of cytosine modifications with human complex traits

scientific article

An exponential combination procedure for set-based association tests in sequencing studies

scientific article published on 15 November 2012

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

article

Genetic association signal near NTN4 in Tourette syndrome

scientific article

Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer

scientific article published on November 2016

List of works by Eric R. Gamazon

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

Obesity-associated variants within FTO form long-range functional connections with IRX3

A gene-based association method for mapping traits using reference transcriptome data

The genetic architecture of type 2 diabetes

SCAN: SNP and copy number annotation

Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue

Genome-wide association study of obsessive-compulsive disorder.

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.

Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

Genome-wide association study of Tourette's syndrome

Population differences in microRNA expression and biological implications

The missing association: sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans

Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals

Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis

Genetic architecture of microRNA expression: implications for the transcriptome and complex traits

Campylobacter jejuni type VI secretion system: roles in adaptation to deoxycholic acid, host cell adherence, invasion, and in vivo colonization

Exprtarget: an integrative approach to predicting human microRNA targets

Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

Genomics of alternative splicing: evolution, development and pathophysiology

Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait

A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci

On sharing quantitative trait GWAS results in an era of multiple-omics data and the limits of genomic privacy

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Variants affecting exon skipping contribute to complex traits.

Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death

Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs

Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

The impact of human copy number variation on gene expression: Figure 1

Ethnicity-specific pharmacogenetics: the case of warfarin in African Americans

Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy

Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.

PACdb: a database for cell-based pharmacogenomics

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations

Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers

Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients

Poly-omic prediction of complex traits: OmicKriging

Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci

Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases

Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver

A genome-wide integrative study of microRNAs in human liver

Linking the genetic architecture of cytosine modifications with human complex traits

An exponential combination procedure for set-based association tests in sequencing studies

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Genetic association signal near NTN4 in Tourette syndrome

Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer