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List of works by Hans Bisgaard

17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry

article

17q21 gene variation is not associated with asthma in adulthood

scientific article published in January 2015

17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use

scientific article published on 09 July 2018

4th Pediatric Allergy and Asthma Meeting (PAAM)

scientific article (publication date: November 2016)

A Clinical Comparison of Aerosol and Powder Administration of Beclomethasone Dipropionate in Childhood Asthma

scientific article published on 01 July 1984

A Protocol for Extraction of Infective Viromes Suitable for Metagenomics Sequencing from Low Volume Fecal Samples

scientific article published on 20 July 2019

A clinical pharmacology study of fixed vs. free combination of inhaled beclometasone dipropionate and formoterol fumarate dry powder inhalers in asthmatic adolescents

scientific article

A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma

scientific article

A genome-wide association meta-analysis identifies new childhood obesity loci

scientific article

A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways.

scientific article

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

scientific article

A mathematical model of aerosol holding chambers

scientific article published in January 1999

A metal aerosol holding chamber devised for young children with asthma

scientific article published on 01 May 1995

A new technique for ranking vascular corticosteroid effects in humans using laser-Doppler velocimetry

scientific article

A non-electrostatic spacer for aerosol delivery

scientific article

A novel common variant in DCST2 is associated with length in early life and height in adulthood

scientific article published on 3 October 2014

A novel method for assessing unchallenged levels of mediators in nasal epithelial lining fluid

scientific article published on 20 March 2010

A randomized trial of montelukast in respiratory syncytial virus postbronchiolitis

scientific article published on 3 October 2002

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

scientific article

A specific assay for leukotriene B4 in human whole blood

scientific article

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

Abstract of the Scientific Literature

scientific article published on 01 September 2019

Accuracy of whole-body plethysmography requires biological calibration

scientific article

Acute relief of exercise-induced bronchoconstriction by inhaled formoterol in children with persistent asthma.

scientific article published on May 2006

Adrenal function in asthmatic children treated with inhaled budesonide

scientific article

Adrenal function in children with bronchial asthma treated with beclomethasone dipropionate or budesonide

scientific article published on 01 June 1988

Aerosol particle size does not predict pharmacokinetic determined lung dose in children.

scientific article

Age dependent systemic exposure to inhaled salbutamol

scientific article

Airway immune mediator levels during asthma-like symptoms in young children and their possible role in response to azithromycin

scientific article published on 04 November 2020

Airway mucosal immune-suppression in neonates of mothers receiving A(H1N1)pnd09 vaccination during pregnancy.

scientific article

Airway obstruction and bronchial reactivity from age 1 month until 13 years in children with asthma: A prospective birth cohort study

article by Henrik Wegener Hallas et al published January 2019 in PLOS MEDICINE

Alcohol intake in pregnancy increases the child's risk of atopic dermatitis. the COPSAC prospective birth cohort study of a high risk population

scientific article

Allergen Specificity in Specific IgE Cutoff

scientific article published on 18 May 2020

Allergen-induced increase of eosinophil cationic protein in nasal lavage fluid: Effect of the glucocorticoid budesonide

scientific article published on 01 May 1990

Allergic rhinitis is associated with otitis media with effusion: a birth cohort study.

scientific article published in November 2012

Allergic sensitization at school age is a systemic low-grade inflammatory disorder.

scientific article published on 19 December 2016

Altered response to A(H1N1)pnd09 vaccination in pregnant women: a single blinded randomized controlled trial

scientific article

Ambient air pollution triggers wheezing symptoms in infants.

scientific article published on 11 February 2008

Amplicon sequencing provides more accurate microbiome information in healthy children compared to culturing

scientific article published on 05 August 2019

An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children

scientific article

Antibiotic exposure in infancy and development of BMI and body composition in childhood

scientific article published on 27 November 2019

Antibiotic use during pregnancy alters the commensal vaginal microbiota.

scientific article

Antibiotics in Pregnancy Increase Children's Risk of Otitis Media and Ventilation Tubes

scientific article published on 11 January 2017

Assessment of bronchial hyperresponsiveness in preschool children: methodological issues

scientific article published on January 1996

Association between allergic rhinitis and hospital resource use among asthmatic children in Norway

scientific article

Association between childhood asthma and attention deficit hyperactivity or autism spectrum disorders: a systematic review with meta-analysis

scientific article published on 30 September 2020

Association between respiratory infections in early life and later asthma is independent of virus type

scientific article published on 21 April 2015

Association between whole-blood polyunsaturated fatty acids in pregnant women and early fetal weight

scientific article published on 12 June 2013

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring: A 6-Year Follow-up of a Randomized Clinical Trial

scientific article published on 05 August 2019

Association of bacteria and viruses with wheezy episodes in young children: prospective birth cohort study

scientific article

Associations between Inhaled Corticosteroid Use in the First 6 Years of Life and Obesity-related Traits

scientific article published in 2021

Asthma-like Symptoms in Young Children Increase the Risk of COPD

scientific article published on 11 June 2020

Atopic endotype in childhood.

scientific article published on 17 November 2015

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

scientific article published on 01 September 2018

Automatic Actuation of a Dry Powder Inhaler into a Nonelectrostatic Spacer ⬇️

scientific article published on February 1, 1998

Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial

scientific article published on 15 December 2015

Bacteria-induced histamine release from human bronchoalveolar cells and blood leukocytes

scientific article published in January 1991

Bioadhesive microspheres as a potential nasal drug delivery system

Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage

scientific article published on 6 February 2017

Biomarkers of exposure to environmental tobacco smoke in infants

scientific article published in 2007

Birth weight and risk of asthma in 3-9-year-old twins: exploring the fetal origins hypothesis

scientific article published on 8 December 2009

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

scientific article

Blood lipid levels associate with childhood asthma, airway obstruction, bronchial hyperresponsiveness, and aeroallergen sensitization

scientific article published on 3 July 2015

Breast milk n-3 long-chain polyunsaturated fatty acids and blood pressure: an individual participant meta-analysis

scientific article published on 20 June 2020

Breast-feeding does not protect against allergic sensitization in early childhood and allergy-associated disease at age 7 years

scientific article

Bronchodilation and bronchoprotection in asthmatic preschool children from formoterol administered by mechanically actuated dry-powder inhaler and spacer.

scientific article published in July 2001

Bronchoprotection with a leukotriene receptor antagonist in asthmatic preschool children.

scientific article published in July 2000

Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma

scientific article

Budesonide/formoterol maintenance and reliever therapy in adolescent patients with asthma

scientific article

Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma

scientific article published on December 2006

CDHR3 Genetics and Rhinovirus C Respiratory Illnesses

scientific article published on 9 November 2017

CDHR3 gene variation and childhood bronchiolitis.

scientific article published on 03 August 2017

Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant

scientific article published on 14 October 2017

Causal direction between respiratory syncytial virus bronchiolitis and asthma studied in monozygotic twins

scientific article published on 30 April 2010

Cesarean Delivery and Body Mass Index at 6 Months and Into Childhood

scientific article published on 01 June 2017

Cesarean section and chronic immune disorders

scientific article published on December 2014

Cesarean section changes neonatal gut colonization

scientific article published on April 2016

Changes in body water distribution during treatment with inhaled steroid in pre-school children

scientific article

Changes in risk of hospital readmission among asthmatic children in Denmark, 1978-93

scientific article

Chemotactic Activity of LTB4in Man

scientific article published on 01 July 1986

Childhood asthma after bacterial colonization of the airway in neonates

scientific article published in October 2007

Childhood asthma: Danish guidelines for diagnosis and treatment

scientific article published in August 2013

Children Monosensitized to Can f 5 Show Different Reactions to Male and Female Dog Allergen Extract Provocation: A Randomized Controlled Trial

scientific article published on 19 December 2019

Children with Asthma Have Fixed Airway Obstruction through Childhood Unaffected by Exacerbations

scientific article published on 09 November 2019

Children with allergic and nonallergic rhinitis have a similar risk of asthma ⬇️

scientific article published on September 1, 2010

Children with asthma by school age display aberrant immune responses to pathogenic airway bacteria as infants

scientific article published on 4 March 2014

Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.

scientific article published on 21 November 2008

Chronic Chlamydia pneumoniae lung infection: a neglected explanation for macrolide effects in wheezing and asthma? - Authors' reply

scientific article published on 2 March 2016

Classification of atopic hand eczema and the filaggrin mutations

scientific article

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

scientific article published on 10 September 2015

Clinical effect of Diskus ™ dry-powder inhaler at low and high inspiratory flow-rates in asthmatic children

scientific article published on 01 February 1998

Clinical efficacy of nebulized drugs

article

Clinical presentation of atopic dermatitis by filaggrin gene mutation status during the first 7 years of life in a prospective cohort study ⬇️

scientific article

Coarse and fine particles but not ultrafine particles in urban air trigger hospital admission for asthma in children

scientific article published on 9 December 2011

Cold air challenge and specific airway resistance in preschool children

scientific article

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

scientific article

Common variants at 12q15 and 12q24 are associated with infant head circumference

scientific article published on 15 April 2012

Comparative study of budesonide as a nebulized suspension vs pressurized metered-dose inhaler in adult asthmatics

scientific article published on 01 January 1998

Comparisons of the complementary effect on exhaled nitric oxide of salmeterol vs montelukast in asthmatic children taking regular inhaled budesonide

scientific article published in September 2003

Consortium genome-wide meta-analysis for childhood dental caries traits

Consortium-based genome-wide meta-analysis for childhood dental caries traits

scholarly article by Simon Haworth published in September 2018

Controlled Trial of Inhaled Budesonide in Patients with Cystic Fibrosis and Chronic BronchopulmonaryPseudomonas aeruginosaInfection

scientific article published on 01 October 1997

Cord blood 25(OH)-vitamin D deficiency and childhood asthma, allergy and eczema: the COPSAC2000 birth cohort study

scientific article

Cord blood Th2-related chemokine CCL22 levels associate with elevated total-IgE during preschool age

scientific article published on 01 November 2012

Correction: Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritization

scientific article published on 23 July 2020

Cost-effectiveness of fluticasone propionate administered via metered-dose inhaler plus babyhaler spacer in the treatment of asthma in preschool-aged children

scientific article published in December 2001

Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation

scientific article

DENND1B gene variants associate with elevated exhaled nitric oxide in healthy high-risk neonates

article

Daily home measurements of exhaled nitric oxide in asthmatic children during natural birch pollen exposure

scientific article

Data representations and -analyses of binary diary data in pursuit of stratifying children based on common childhood illnesses

scientific article published in PLoS ONE

Deep phenotyping of the unselected COPSAC2010 birth cohort study.

scientific article

Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach.

scientific article published on October 2008

Delayed Motor Milestones Achievement in Infancy Associates with Perturbations of Amino Acids and Lipid Metabolic Pathways

scientific article published on 19 August 2020

Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma

scientific article published on 01 November 2020

Delivery of Inhaled Medication to Children ⬇️

scientific article published on January 1, 1997

Delivery options for inhaled therapy in children under the age of 6 years

article

Demands on spacer devices for young children

scientific article published on 01 January 1997

Detection of leukotriene C4-like immunoreactivity in tear fluid from subjects challenged with specific allergen

scientific article published on 01 March 1984

Determinants of lung function and airway hyperresponsiveness in asthmatic children

scientific article published on 2 March 2007

Determinants of neurodevelopment in early childhood – results from the copenhagen prospective studies on asthma in childhood ( COPSAC 2010 ) mother–child cohort

scientific article published on 21 March 2019

Development of Atopic Dermatitis During the First 3 Years of Life

article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Disagreement between skin prick test and specific IgE in young children

scientific article published on 30 November 2014

Discriminative capacity of bronchodilator response measured with three different lung function techniques in asthmatic and healthy children aged 2 to 5 years

scientific article published in August 2001

Distinct immune phenotypes in infants developing asthma during childhood

scientific article published on 01 February 2020

Divergent response profile in activated cord blood T cells from first-born child implies birth-order-associated in utero immune programming

scientific article published on 2 December 2015

Domestic dog exposure at birth reduces the incidence of atopic dermatitis.

scientific article published on 6 July 2016

Drug delivery from inhaler devices

scientific article published in October 1996

Duration of action of formoterol and salbutamol dry-powder inhalation in prevention of exercise-induced asthma in children

scientific article published on 01 June 1996

Duration of wheezy episodes in early childhood is independent of the microbial trigger

scientific article published on 19 June 2015

Early and late nasal symptom response to allergen challenge. The effect of pretreatment with a glucocorticosteroid spray.

scientific article

Early bioavailability of inhaled salbutamol reflects lung dose in children

scientific article published on 10 April 2008

Early growth characteristics and the risk of reduced lung function and asthma: A meta-analysis of 25,000 children

scientific article published on 5 November 2015

Early indoor aeroallergen exposure is not associated with development of sensitization or allergic rhinitis in high-risk children

article

Early life bacterial airway colonization, local immune mediator response and risk of otitis media

scientific article published on 29 June 2020

Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children

scientific article published in October 2022

Ecological succession in the vaginal microbiota during pregnancy and birth

scientific article published on 02 June 2020

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

scientific article published on 11 December 2018

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

Effect of High-Dose vs Standard-Dose Vitamin D Supplementation in Pregnancy on Bone Mineralization in Offspring Until Age 6 Years: A Prespecified Secondary Analysis of a Double-Blinded, Randomized Clinical Trial

scientific article published on 24 February 2020

Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial

scientific article published on January 2016

Effect of delivery device on systemic exposure to inhaled fluticasone propionate in children with asthma.

scientific article

Effect of electrostatic charge in plastic spacers on the lung delivery of HFA-salbutamol in children

scientific article

Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial

scientific article published in the British Medical Journal

Effect of leukotriene D4 on nasal mucosal blood flow, nasal airway resistance and nasal secretion in humans

scientific article

Effect of long‐acting β2 agonists on exacerbation rates of asthma in children ⬇️

scientific article published on November 1, 2003

Effect of plastic spacer handling on salbutamol lung deposition in asthmatic children

scientific article published on November 2002

Effect of prenatal bisphenol A exposure on early childhood body mass index through epigenetic influence on the insulin-like growth factor 2 receptor (IGF2R) gene

scientific article published on 06 July 2020

Effects of Leukotrienes on Neutrophil Migration, and on Production and Action of Lymphokines

article

Effects of cysteinyl leukotrienes and leukotriene receptor antagonists on markers of inflammation

scientific article

Effects of synthetic leukotriene D-4 on the local regulation of blood flow in human subcutaneous tissue

scientific article published in February 1985

Efficacy of steroid treatments in the asthmatic preschool child

scientific article published in January 2002

Eicosanoids in skin UV inflammation.

scientific article

Elevated Eosinophil Protein X in Urine from Healthy Neonates Precedes Development of Atopy in the First 6 Years of Life ⬇️

scientific article published on September 15, 2011

Elevated Exhaled Nitric Oxide in High-Risk Neonates Precedes Transient Early but Not Persistent Wheeze

scientific article published on 18 March 2010

Endotyping early childhood asthma by quantitative symptom assessment

Environmental and Genetic Determinants of Serum 25(OH)-Vitamin D Levels during Pregnancy and Early Childhood

scientific article published on 21 October 2019

Environmental grass pollen levels in utero and at birth and cord blood IgE: Analysis of three birth cohorts

scientific article published on 07 July 2018

Environmental shaping of the bacterial and fungal community in infant bed dust and correlations with the airway microbiota

scientific article published on 07 August 2020

Epidemiology and Risk Factors of Infection in Early Childhood

scientific article published on 24 May 2018

Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age

scientific article published on 18 July 2020

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

scholarly article by Zala Jevnikar et al published June 2018 in The Journal of Allergy and Clinical Immunology

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

scholarly article published in Nature Genetics

Evidence-based medicines for children: ethical aspects

article

Exhaled nitric oxide predicts exercise-induced bronchoconstriction in asthmatic school children

scientific article published in October 2005

Experimentally induced nasal hypersecretion does not reduce the efficacy of intranasal levocabastine

scientific article published on 01 December 1998

Exploring the association between severe respiratory syncytial virus infection and asthma: a registry-based twin study

scientific article published on 12 March 2009

Extrapolating evidence beyond age groups

scientific article published on 5 March 2008

FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

scientific article

Fatty acid composition of human milk in atopic Danish mothers

scientific article published in July 2006

FeNO and Exercise Testing in Children at Risk of Asthma

scientific article

FeNO measured at fixed exhalation flow rate during controlled tidal breathing in children from the age of 2 yr.

scientific article published in March 2001

Feasibility of repetitive lung function measurements by raised volume rapid thoracoabdominal compression during methacholine challenge in young infants

scientific article published on 20 October 2007

Filaggrin gene variants and atopic diseases in early childhood assessed longitudinally from birth

scientific article published on 21 June 2010

Filaggrin loss-of-function mutation R501X and 2282del4 carrier status is associated with fissured skin on the hands: results from a cross-sectional population study

scientific article published on 02 November 2011

Filaggrin null alleles are not associated with hand eczema or contact allergy

scientific article published on 26 October 2007

Fine particle mass from the Diskus inhaler and Turbuhaler inhaler in children with asthma

scientific article published on 01 May 1998

Fish Oil Supplementation in Pregnancy Increases Gestational Age, Size for Gestational Age, and Birth Weight in Infants: A Randomized Controlled Trial

Fish Oil in Pregnancy and Asthma in Offspring

scientific article published on 01 March 2017

Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring

scientific article

Fish oil supplementation during pregnancy is protective against asthma/wheeze in offspring

scientific article published on 19 June 2019

Fish-oil supplementation in pregnancy, child metabolomics and asthma risk

scientific article published on 06 August 2019

Flow-dependent effect of formoterol dry-powder inhaled from the Aerolizerfi

scientific article published on 01 September 1997

Fraction of exhaled nitric oxide and bronchial responsiveness are associated and continuous traits in young children independent of asthma.

scientific article published in December 2012

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

scientific article

Future options for aerosol delivery to children

scientific article

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

scientific article published on 04 September 2019

Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure

scientific article published in June 2008

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

scientific article published on March 2016

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

Genetic association study of childhood aggression across raters, instruments, and age

scientific article

Genetic associations with viral respiratory illnesses and asthma control in children.

scientific article

Genetic, Clinical, and Environmental Factors Associated With Persistent Atopic Dermatitis in Childhood

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

scholarly article by Johannes Waage et al published August 2018 in Nature Genetics

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

article

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

scientific article published on 3 January 2018

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Heterogeneity of FeNO response to inhaled steroid in asthmatic children

scientific article

High breast milk IL-1β level is associated with reduced risk of childhood eczema.

scientific article published on 2 June 2016

High-Dose Vitamin D Supplementation During Pregnancy and Asthma in Offspring at the Age of 6 Years

High-Dose Vitamin D Supplementation in Pregnancy and Neurodevelopment in Childhood: A Prespecified Secondary Analysis of a Randomized Clinical Trial

scientific article published on 01 December 2020

Histamine release after nasal challenge with anti-IgE and Staphylococcus aureus in patients with allergic rhinitis

scholarly article by T Dein et al published 1992 in Pneumonologia i Alergologia Polska

Human Leukocyte Cyclic AMP and Cyclic GMP Levels during Chemotaxis in Delayed Type Hypersensitivity

scientific article published on 01 April 1984

Human leukocyte mobilization and morphology in nickel contact allergy using a skin chamber technique

scientific article published on 01 January 1981

Hyperventilation with cold versus dry air in 2- to 5-year-old children with asthma.

scientific article published on 12 November 2004

Immune-mediated diseases and microbial exposure in early life.

scientific article

Impact of constant and breath-synchronized nebulization on inhaled mass of nebulized budesonide in infants and children.

scientific article published in September 1999

In utero exposure to 25-hydroxyvitamin D and risk of childhood asthma, wheeze, and respiratory tract infections: A meta-analysis of birth cohort studies.

scientific article

In vitro performance of three combinations of spacers and pressurized metered dose inhalers for treatment in children

scientific article published on 01 August 1998

Incidence and Determinants of Ventilation Tubes in Denmark

scientific article

Increased concordance of severe respiratory syncytial virus infection in identical twins

scientific article published in March 2008

Increased risk of eczema but reduced risk of early wheezy disorder from exclusive breast-feeding in high-risk infants

Increased risk of pneumonia and bronchiolitis after bacterial colonization of the airways as neonates.

scientific article

Individuals who are homozygous for the 2282del4 and R501X filaggrin null mutations do not always develop dermatitis and complete long-term remission is possible

scientific article published on 19 April 2011

Infant acetaminophen use associates with early asthmatic symptoms independently of respiratory tract infections: the Copenhagen Prospective Study on Asthma in Childhood 2000 (COPSAC(2000)) cohort.

scientific article published on 24 October 2012

Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

scientific article published on 01 November 2019

Inhaled budesonide for treatment of recurrent wheezing in early childhood

scientific article published in September 1990

Interaction between Asthma and Lung Function Growth in Early Life ⬇️

scientific article published on March 29, 2012

Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

scientific article published on 26 December 2019

Intermittent Inhaled Corticosteroids in Infants with Episodic Wheezing

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

Knemometry is more sensitive to systemic effects of inhaled corticosteroids in children with asthma than 24-hour urine cortisol excretion

scientific article published on 15 December 2016

Lactoferrin, myeloperoxidase, lysozyme and eosinophil cationic protein in exudate in delayed type hypersensitivity

scientific article published in February 1988

Large-scale benchmarking reveals false discoveries and count transformation sensitivity in 16S rRNA gene amplicon data analysis methods used in microbiome studies.

scientific article

Laser Doppler flowmeter

scientific article

Leukotriene B4 produces hyperalgesia in humans

scientific article published on November 1985

Leukotriene C4 and histamine in early allergic reaction in the nose

scientific article published in April 1988

Leukotriene D4 increases nasal blood flow in humans

scientific article published on April 1984

Leukotriene D4 induces bronchoconstriction in man

scientific article published on 01 August 1983

Leukotriene modifiers in pediatric asthma management

scientific article

Leukotriene- and Histamine-Induced Increases in Vascular Permeability and Interstitial Transport in the Skin

scientific article published on 01 May 1985

Leukotrienes and Prostaglandins in Asthma

scientific article published on 01 August 1984

Leukotrienes in allergic and inflammatory conditions

scientific article

Leukotrienes, leukotriene receptor antagonists, and rhinitis

scientific article

Levalbuterol has not been established to have therapeutic advantage over racemic albuterol

scientific article published in August 2002

Levels of Systemic Low-grade Inflammation in Pregnant Mothers and Their Offspring are Correlated

scientific article published on 28 February 2019

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

scientific article published in January 2018

Limited clinical value of exhaled volatile organic compound measurements in childhood asthma

article published in 2018

Living with cat and dog increases vaginal colonization with E. coli in pregnant women

scientific article

Loci for primary ciliary dyskinesia map to chromosome 16p12.1-12.2 and 15q13.1-15.1 in Faroe Islands and Israeli Druze genetic isolates.

scientific article published in March 2004

Long-acting beta(2)-agonists in management of childhood asthma: A critical review of the literature

scientific article

Long-acting β2 agonists and paediatric asthma

scientific article published in The Lancet

Long-term exposure to indoor air pollution and wheezing symptoms in infants

scientific article published on 14 October 2009

Long-term studies of the natural history of asthma in childhood ⬇️

scientific article published on August 1, 2010

Longitudinal study of lung function in a cohort of primary ciliary dyskinesia

scientific article published in October 1997

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

scientific article published in Nature Communications

Low-frequency variation inTP53has large effects on head circumference and intracranial volume

Lung Deposition of Inhaled Drugs Increases with Age

Lung function after allogeneic bone marrow transplantation for leukaemia or lymphoma

scientific article

Lung function and bronchial responsiveness after Mycoplasma pneumoniae infection in early childhood.

scientific article

Lung function and short-term outcome in young asthmatic children.

scientific article

Lung function measurement in awake young children.

scientific article

Lung function response to cold air challenge in asthmatic and healthy children of 2-5 years of age.

scientific article

Maternal High-Dose Vitamin D Supplementation and Offspring Bone Mineralization Until Age 6 Years-Reply

scientific article published on 10 August 2020

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Maternal antibiotic use and risk of asthma in offspring--Authors' reply

scientific article

Maternal fatty acid desaturase genotype correlates with infant immune responses at 6 months

article

Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study

scientific article published on 24 July 2014

Maternal vaginal microflora during pregnancy and the risk of asthma hospitalization and use of antiasthma medication in early childhood

scientific article

Maturation of the gut microbiome and risk of asthma in childhood

scientific article published on 10 January 2018

Measurement of lung function in awake 2-4-year-old asthmatic children during methacholine challenge and acute asthma: a comparison of the impulse oscillation technique, the interrupter technique, and transcutaneous measurement of oxygen versus whole

scientific article published on 01 May 1996

Measurement of lung function in awake 2–4‐year‐old asthmatic children during methacholine challenge and acute asthma: A comparison of the impulse oscillation technique, the interrupter technique, and transcutaneous measurement of oxygen versus

Measurement of secretion in nasal lavage

scientific article published on 01 August 1987

Measurement of the specific airway resistance by plethysmography in young children accompanied by an adult

scientific article published in July 1997

Measurements of exhaled nitric oxide in healthy subjects age 4 to 17 years

scientific article

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

scientific article published on 07 May 2020

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

scientific article

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

scientific article

Metagenomic heterogeneity explains dual immune effects of endotoxins

scholarly article by Susanne Brix et al published January 2015 in The Journal of Allergy and Clinical Immunology

Middle ear effusion, ventilation tubes and neurological development in childhood

scientific article published in 2023

Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial

scientific article

Montelukast in RSV-bronchiolitis

scientific article published in February 2004

Montelukast or salmeterol combined with an inhaled steroid in adult asthma: design and rationale of a randomized, double-blind comparative study (the IMPACT Investigation of Montelukast as a Partner Agent for Complementary Therapy-trial).

scientific article published in June 2000

Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma

scientific article published on 12 November 2004

Montelukast, a leukotriene receptor antagonist, for the treatment of persistent asthma in children aged 2 to 5 years

scientific article

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

scientific article published on 19 October 2015

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

scientific article published on 22 December 2017

Multiple Breath Washout for Diagnosing Asthma and Persistent Wheeze in Young Children

scientific article published on 01 May 2019

NKG2D gene variation and susceptibility to viral bronchiolitis in childhood

article

NO in Exhaled Air of Asthmatic Children Is Reduced by the Leukotriene Receptor Antagonist Montelukast

Nasal inhalation of budesonide from a spacer in children with perennial rhinitis and asthma

scientific article published on 01 April 1998

Nebulization and selective deposition of LTD4in human lungs

scientific article published on 01 July 1987

Neonatal Urine Metabolic Profiling and Development of Childhood Asthma

scientific article published on 16 September 2019

Neonatal airway colonization is associated with troublesome lung symptoms in infants.

scientific article published in October 2013

Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants

scientific article published on 17 June 2012

Neonatal colonization with Staphylococcus aureus is not associated with development of atopic dermatitis.

scientific article published on 23 February 2009

Neonatal cytokine profile in the airway mucosal lining fluid is skewed by maternal atopy

scientific article published on 10 November 2011

Neonatal metabolome of caesarean section and risk of childhood asthma

scientific article published in 2021

Neonatal size in term children is associated with asthma at age 7, but not with atopic dermatitis or allergic sensitization.

scientific article published on 2 March 2012

Neonates colonized with pathogenic bacteria in the airways have a low-grade systemic inflammation.

scientific article

Neonates with reduced neonatal lung function have systemic low-grade inflammation

scientific article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

New parameters for evaluation of blood flow in patients with leg ulcers.

scientific article

New time-saving predictor algorithm for multiple breath washout in adolescents

scientific article published on 22 March 2016

No evidence of intrauterine sensitization against inhalant allergens

article

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

scientific article

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry.

scientific article

Objective assessment of levels and patterns of physical activity in preschool children.

scientific article published on 14 June 2013

Objective assessments of allergic and nonallergic rhinitis in young children

article

Observer variability of lung function measurements in 2-6-yr-old children

scientific article published in September 2000

Optimal timing of influenza vaccine during pregnancy: A systematic review and meta-analysis

scientific article published on 05 June 2019

Oropharyngeal Microbiota Clusters in Children with Asthma or Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways, and Exacerbation Risk

scientific article published in 2023

PEP-spacer: an adaptation for administration of MDI to infants

scientific article published on 01 July 1989

Parent-specific effects on risk of developing allergic sensitization and asthma in childhood

scientific article published on 07 July 2020

Pathogenic bacteria colonizing the airways in asymptomatic neonates stimulates topical inflammatory mediator release

scientific article

Perceptions of parents on the participation of their infants in clinical research.

scientific article published on 4 July 2006

Persistent Wheezing in Very Young Preschool Children Reflects Lower Respiratory Inflammation

Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation

scientific article published on 17 January 2020

Pharmacokinetic comparison of inhaled fixed combination vs. the free combination of beclomethasone and formoterol pMDIs in asthmatic children

scientific article published on April 2013

Physical activity in young children is reduced with increasing bronchial responsiveness

Picornavirus-Induced Airway Mucosa Immune Profile in Asymptomatic Neonates

scientific article published on 09 December 2015

Plasma 25-Hydroxyvitamin D Concentrations are Associated with Polyunsaturated Fatty Acid Metabolites in Young Children: Results from the Vitamin D Antenatal Asthma Reduction Trial

scientific article published on 14 April 2020

Plethysmographic measurements of specific airway resistance in young children.

scientific article

Polyunsaturated fatty acid content of mother’s milk is associated with childhood body composition

article

Postmenopausal hormone therapy and asthma-related hospital admission

scientific article published on 8 January 2015

Precision allergy: Separate allergies to male and female dogs

scientific article

Predicting an asthma exacerbation in children 2 to 5 years of age.

scientific article

Predictors of indoor fine particulate matter in infants' bedrooms in Denmark

scientific article published on 6 November 2010

Preeclampsia Associates with Asthma, Allergy, and Eczema in Childhood

scientific article

Prelabor cesarean section bypasses natural immune cell maturation

scholarly article by Anna Hammerich Thysen et al published October 2015 in The Journal of Allergy and Clinical Immunology

Prenatal Vitamin D Supplementation to Improve Health in Offspring

article

Prenatal and postnatal genetic influence on lung function development.

scientific article published on 21 May 2014

Prenatal determinants of neonatal lung function in high-risk newborns

scientific article published on 18 January 2009

Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial

scientific article published on 22 January 2020

Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials

scientific article published on 27 October 2017

Preterm birth, infant weight gain, and childhood asthma risk: a meta-analysis of 147,000 European children

scientific article

Prevalence and predictors of antibiotic administration during pregnancy and birth

scientific article

Prevalence of asthma-like symptoms in young children

article

Production of Leukotrienes in Human Skin and Conjunctival Mucosa after Specific Allergen Challenge

article

Production of peptido-lipid leukotrienes in human tear fluid following antigen challenge

article

Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

scientific article published on 09 November 2019

Public hygiene campaign in denmark during the 2009 H1N1 pandemic had no effect on hospitalization rate of communicable diseases in children.

scientific article

Publisher Correction: Maturation of the gut microbiome and risk of asthma in childhood

scientific article published on 13 February 2018

Quantitation of microcirculatory blood flow changes in human cutaneous tissue induced by inflammatory mediators

scientific article published on September 1984

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

scientific article published on 16 November 2021

Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium

scientific article published on 22 June 2017

Reduced IL-2 response from peripheral blood mononuclear cells exposed to bacteria at 6 months of age is associated with elevated total-IgE and allergic rhinitis during the first 7 years of life.

scientific article published on 2 May 2019

Reduced Steroid Metabolites Identify Infection-Prone Children in Two Independent Pre-Birth Cohorts

scientific article published in 2022

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age.

scientific article published on 22 July 2011

Repeatability of methacholine challenges in 2 to 4-year-old children with asthma, using a new technique for quantitative delivery of aerosol

scientific article published on 01 April 1997

Reply

scientific article published on 12 April 2016

Reply: Allergy is not always the cause of asthma

scientific article

Respiratory medicines for children: current evidence, unlicensed use and research priorities

scientific article published on 19 October 2009

Response of preschool children with asthma symptoms to fluticasone propionate

scientific article

Response to montelukast among subgroups of children aged 2 to 14 years with asthma

scientific article published in April 2003

Rhinovirus wheezing illness and genetic risk of childhood-onset asthma

scientific article published on 27 March 2013

Risk Factors for Wheezing during Infancy A Study of 5953 Infants

scientific article published on 01 September 1987

Risk analysis of early childhood eczema.

scientific article published in June 2009

Risk of Asthma from Cesarean Delivery Depends on Membrane Rupture

scientific article published on 26 January 2016

Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source

scientific article

Role of leukotrienes in asthma pathophysiology

scientific article

SRS-A leukotrienes decrease the activity of human respiratory cilia

scientific article published on 01 March 1987

Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial

scientific article published on 17 January 2018

Safety and tolerability of montelukast in placebo-controlled pediatric studies and their open-label extensions

scientific article published on June 2009

Safety of treatment

scientific article published on April 1996

Season of Birth Impacts the Neonatal Nasopharyngeal Microbiota

scientific article published on 11 May 2020

Season of birth shapes neonatal immune function

scientific article published on 27 October 2015

Sensitivity of bronchial responsiveness measurements in young infants

scientific article published on March 2006

Sensitivity of multiple breath washout to detect mild-to-moderate asthma in adolescence

scientific article published on 29 January 2019

Sensitization does not develop in utero

Sensitization trajectories in childhood revealed by using a cluster analysis

scientific article published on 24 March 2017

Serial lung function and responsiveness in cystic fibrosis during early childhood.

scientific article published on 17 March 2004

Seven-year-old children's perceptions of participating in a comprehensive clinical birth cohort study

article by Anne Gammelgaard & Hans Bisgaard published 22 May 2009 in Clinical Ethics

Shared genetic variants suggest common pathways in allergy and autoimmune diseases

scientific article published on 7 February 2017

Short- and long-term impacts of azithromycin treatment on the gut microbiota in children: A double-blind, randomized, placebo-controlled trial

scientific article published on 23 November 2018

Siblings Promote a Type 1/Type 17-oriented immune response in the airways of asymptomatic neonates

scientific article published on 25 January 2016

Simultaneous treatment of rhinitis and asthma by nasal inhalation of corticosteroid from a spacer

scientific article published on 01 January 1999

Single and multiple time-point allergic sensitization during childhood and risk of asthma by age 13

scientific article published on 12 August 2019

Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations

Specific airway resistance, interrupter resistance, and respiratory impedance in healthy children aged 2–7 years

scientific article published on 01 May 1998

Stable admission rate for acute asthma in Danish children since 1977.

scientific article published on 13 August 2015

Staphylococcus aureus and influenza A virus stimulate human bronchoalveolar cells to release histamine and leukotrienes

scientific article published in April 1989

Study of montelukast for the treatment of respiratory symptoms of post-respiratory syncytial virus bronchiolitis in children

scientific article published on 26 June 2008

Sulphidoleukotrienes in human allergic diseases

scientific article

Summary of recommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma

scientific article published on June 2004

Susceptibility to Lower Respiratory Infections in Childhood is Associated with Perturbation of the Cytokine Response to Pathogenic Airway Bacteria.

scientific article

Symptom burden of atopic dermatitis in early childhood assessed from daily monitoring of symptoms and topical steroid usage

scientific article published on 17 September 2020

Systemic activity of inhaled steroids in 1- to 3-year-old children with asthma

scientific article published in March 2002

Systemic activity of inhaled topical steroid in toddlers studied by knemometry

scientific article published on 01 December 1993

Systemic exposure to inhaled beclometasone/formoterol DPI is age and body size dependent

scientific article published on 17 June 2014

THE ROLE OF INFECTIONS IN PEDIATRIC ASTHMA

Targeting drugs to the respiratory tract

The Brussels Declaration: the need for change in asthma management ⬇️

scientific article

The Copenhagen Prospective Study on Asthma in Childhood (COPSAC): design, rationale, and baseline data from a longitudinal birth cohort study

scientific article

The Effect of Inhaled Fluticasone Propionate in the Treatment of Young Asthmatic Children

article

The Maternal Prenatal and Offspring Early‐Life Gut Microbiome of Childhood Asthma Phenotypes

scientific article published in 2022

The PCDH1 gene and asthma in early childhood

scientific article

The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts

scientific article

The causal direction in the association between respiratory syncytial virus hospitalization and asthma

scientific article published in January 2009

The developing airway and gut microbiota in early life is influenced by age of older siblings

scientific article published in 2022

The developing hypopharyngeal microbiota in early life

scientific article published on 30 December 2016

The effect of inhaled budesonide on symptoms, lung function, and cold air and methacholine responsiveness in 2- to 5-year-old asthmatic children.

scientific article published in October 2000

The effect of leukotriene C4 and D4 on cutaneous blood flow in humans

scientific article published on June 1982

The effect of leukotrienes C4 and D4 on microcirculatory flow in humans.

scientific article published on July 1983

The possible role of LTD4 in asthma in humans investigated in vivo

scientific article published on 01 January 1984

The role of the 17q21 genotype in the prevention of early childhood asthma and recurrent wheeze by vitamin D

scientific article published on 24 October 2019

The systemic exposure to inhaled beclometasone/formoterol pMDI with valved holding chamber is independent of age and body size.

scientific article published on 16 April 2014

Towards improved aerosol devices for the young child

scientific article published on 01 January 1999

Transfer of maternal IgE can be a common cause of increased IgE levels in cord blood ⬇️

scientific article published on September 1, 2010

Twelve-month safety and efficacy of inhaled fluticasone propionate in children aged 1 to 3 years with recurrent wheezing

scientific article published in February 2004

Understanding mild persistent asthma in children: the next frontier

scientific article

Upper and Lower Airway Patency Are Associated in Young Children

scientific article published on 29 January 2010

Urbanized microbiota in infants, immune constitution and later risk of atopic diseases

scientific article published on 15 December 2020

Use of antibiotics during pregnancy increases the risk of asthma in early childhood

scientific article published on 6 November 2012

Use of budesonide Turbuhaler® in young children suspected of asthma

scientific article published on 01 April 1994

Use of inhaled corticosteroids in pediatric asthma

scientific article published on September 1, 1997

VEGFA variants are associated with pre-school lung function, but not neonatal lung function.

scientific article published in November 2013

Validation of a pediatric caregiver diary to measure symptoms of postacute respiratory syncytial virus bronchiolitis

scientific article

Validity of information on atopic disease and other illness in young children reported by parents in a prospective birth cohort study

scientific article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

scientific article published on 02 September 2019

Variants of DENND1B associated with asthma in children

scientific article

Variations in Pediatric Asthma Hospitalization Rates and Costs Between and Within Nordic Countries

scientific article published on 01 May 2004

Vascular effects of leukotriene D4 in human skin

scientific article

Vertical Transfer of Metabolites Detectable from Newborn’s Dried Blood Spot Samples Using UPLC-MS: A Chemometric Study

scientific article published in 2022

Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages

scientific article published on 17 January 2020

Vitamin D Supplement During Pregnancy and Enamel Defects in Offspring-Reply

scientific article published on 27 January 2020

What dose fraction represents the respirable dose? ⬇️

scientific article published on 01 November 1997

What drives prescription patterns in pediatric asthma management?

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

scientific article published on 23 September 2019

[Formoterol--a prolonged-action beta 2 agonist]

scientific article published on 01 November 1993

[No risk of development of osteoporosis or inhibition of growth in children with asthma treated with inhaled corticosteroids]

scientific article published on 01 June 2005

[Pediatric pulmonology]

scientific article published on 01 November 2001

[Steroid treatment of asthmatic children]

scientific article published on 01 November 1997

[The Marstock method. A method for measuring sensitivity and pain thresholds]

scientific article published on 01 November 1986

[Treatment of asthmatic bronchitis in small children with steroid inhalation]

scientific article published on 01 January 1993

“To wheeze or not to wheeze”: That is not the question

“To wheeze or not to wheeze”: That is not the question—the sequel

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