List of works by Dirk Hockemeyer

4D cell biology: big data image analytics and lattice light-sheet imaging reveal dynamics of clathrin-mediated endocytosis in stem cell-derived intestinal organoids.

scientific article published on 06 September 2018

<i>TINF2</i> is a haploinsufficient tumor suppressor that limits telomere length

scientific article published on 01 December 2020

A drug-inducible system for direct reprogramming of human somatic cells to pluripotency

scientific article

Analysis of muntjac deer genome and chromatin architecture reveals rapid karyotype evolution

scientific article published on 01 September 2020

Cancer-associated TERT promoter mutations abrogate telomerase silencing

scientific article published on 21 July 2015

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

scientific article

Control of telomerase action at human telomeres

scientific article published on November 2015

Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System.

scientific article

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

scientific article published on 19 October 2011

Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

scientific article

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

scientific article (publication date: September 2009)

Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo

scientific article

Engineered telomere degradation models dyskeratosis congenita

scientific article published on 11 June 2008

Erratum: Corrigendum: Telomere protection by mammalian Pot1 requires interaction with Tpp1

scholarly article published in Nature Structural & Molecular Biology

Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation

scientific article published on 2 February 2016

Functional dissection of human and mouse POT1 proteins

scientific article

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

scientific article

Gene targeting in human pluripotent cells

scientific article published on January 2010

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

scientific article published on 14 July 2011

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

scientific article (publication date: September 2014)

Genetic engineering of human pluripotent cells using TALE nucleases

scientific article (publication date: 7 July 2011)

Genome editing 101: let's go digital

scientific article published in March 2014

Genome editing in human pluripotent stem cells using site-specific nucleases

scientific article published in January 2015

Genome-edited human stem cells expressing fluorescently labeled endocytic markers allow quantitative analysis of clathrin-mediated endocytosis during differentiation

scientific article published on 06 July 2018

Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons

scientific article

Highly efficient generation of isogenic pluripotent stem cell models using prime editing

scientific article published in 2022

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells.

scientific article

Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells

scientific article

Human stem cell-based disease modeling: prospects and challenges

scientific article

Induced Pluripotent Stem Cells Meet Genome Editing

scientific article

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

scientific article published on July 2009

Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies

scientific article published on 15 August 2016

Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism

scientific article

Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.

scientific article

Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms.

scientific article published in April 2018

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

scientific article

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

scientific article

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

scientific article (publication date: 6 March 2009)

Potentiation of serum response factor activity by a family of myocardin-related transcription factors

scientific article

Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres

scientific article

SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development

scientific article

TALEN gene knockouts reveal no requirement for the conserved human shelterin protein Rap1 in telomere protection and length regulation

scientific article published on 6 November 2014

Telomere protection by mammalian Pot1 requires interaction with Tpp1

scientific article

Transgene excision has no impact on in vivo integration of human iPS derived neural precursors

scientific article

Transient activation of the UPR is an essential step in the acquisition of pluripotency during reprogramming

scientific article published on 10 April 2019

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