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List of works by Daniel Otzen

A SAXS study of glucagon fibrillation

scientific article published in March 2009

A Ser residue influences the structure and stability of a Pro-kinked transmembrane helix dimer

A Versatile Approach to β-Amyloid Fibril-Binding Compounds Exploiting the Shirakawa/Hayashi Protocol fortrans-Alkene Synthesis

scientific article published in 2009

A comparative study of the unfolding of the endoglucanase Cel45 from Humicola insolens in denaturant and surfactant

scientific article published on September 1999

A kinetic analysis of the folding and unfolding of OmpA in urea and guanidinium chloride: single and parallel pathways

scientific article

A new class of hybrid secretion system is employed in Pseudomonas amyloid biogenesis

scientific article published on 15 August 2017

A simple way to measure protein refolding rates in water

scientific article published in October 2001

A thermodynamic analysis of fibrillar polymorphism

scientific article published on 9 April 2010

AFM study of glucagon fibrillation via oligomeric structures resulting in interwoven fibrils

scientific article

AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon

Activation, inhibition, and destabilization of Thermomyces lanuginosus lipase by detergents

scientific article

Aggregation and fibrillation of bovine serum albumin

scientific article published on 6 July 2007

Aggregation as the basis for complex behaviour of cutinase in different denaturants

scientific article published on 30 November 2006

Aggregation of S6 in a quasi-native state by sub-micellar SDS.

scientific article

Alternative membrane protein conformations in alcohols

scientific article published on 20 March 2007

Amyloid adhesins are abundant in natural biofilms

scientific article

Amyloid formation in surfactants and alcohols: membrane mimetics or structural switchers?

scientific article published on August 2010

Amyloid formation of α-synuclein based on the solubility- and supersaturation-dependent mechanism

scientific article published on 09 April 2020

Amyloid structure--one but not the same: the many levels of fibrillar polymorphism

scientific article

Amyloid-a state in many guises: survival of the fittest fibril fold

scientific article

Amyloid-like adhesins produced by floc-forming and filamentous bacteria in activated sludge

scientific article

An Aß concatemer with altered aggregation propensities

scientific article published on 7 July 2010

An unusual intrinsically disordered protein from the model legume Lotus japonicus stabilizes proteins in vitro

scientific article published on 8 September 2008

Analysis of protein–protein interactions by mutagenesis: direct versus indirect effects

article

Antagonism, non-native interactions and non-two-state folding in S6 revealed by double-mutant cycle analysis

scientific article

Antibodies against the C-terminus of α-synuclein modulate its fibrillation.

scientific article published on 10 November 2016

Assays for α-synuclein aggregation

scientific article published on 14 December 2010

Assembling Good Amyloid: Some Structures at Last

article

Aβ1-16 can aggregate and induce the production of reactive oxygen species, nitric oxide, and inflammatory cytokines

scientific article

Bacterial RTX toxins allow acute ATP release from human erythrocytes directly through the toxin pore

scientific article

Barriers to folding of the transmembrane domain of the Escherichia coli autotransporter adhesin involved in diffuse adherence

scientific article

Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies

scientific article published on 29 January 2020

Branching in amyloid fibril growth

scientific article published on February 2009

Burst-phase expansion of native protein prior to global unfolding in SDS.

scientific article published in February 2002

Cell-free synthesis and folding of transmembrane OmpA reveals higher order structures and premature truncations

scientific article published on 13 August 2010

Changes in structures of milk proteins upon photo-oxidation.

scientific article

Characterization of dry globular proteins and protein fibrils by synchrotron radiation vacuum UV circular dichroism

scientific article published in September 2008

Co-existence of two different α-synuclein oligomers with different core structures determined by hydrogen/deuterium exchange mass spectrometry.

scientific article published on 16 April 2014

Coexistence of ribbon and helical fibrils originating from hIAPP(20-29) revealed by quantitative nanomechanical atomic force microscopy

scientific article published on 6 February 2013

Compaction of ribosomal protein S6 by sucrose occurs only under native conditions.

scientific article published in February 2006

Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene

scientific article

Concatemers of Outer Membrane Protein A Take Detours in the Folding Landscape

scientific article

Condenser: a statistical aggregation tool for multi-sample quantitative proteomic data from Matrix Science Mascot Distiller™.

scientific article

Conformational Pathway of the Polypeptide Chain of Chymotrypsin Inhibitor-2 Growing from its N Terminusin vitro. Parallels with the Protein Folding Pathway

scientific article published on 01 December 1995

Conformational detours during folding of a collapsed state

scientific article published on 01 June 2005

Conformational plasticity in folding of the split beta-alpha-beta protein S6: evidence for burst-phase disruption of the native state

scientific article published in April 2002

Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures

scientific article published on 07 March 2019

Correspondence between anomalous m- and DeltaCp-values in protein folding

scientific article published in December 2004

Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin

scientific article

Curli Functional Amyloid Systems Are Phylogenetically Widespread and Display Large Diversity in Operon and Protein Structure ⬇️

scientific article published on December 12, 2012

Cyclodextrin-Scaffolded Alamethicin with Remarkably Efficient Membrane Permeabilizing Properties and Membrane Current Conductance

scientific article published on 25 June 2012

Dendrimer Effects on Peptide and Protein Fibrillation

scientific article published on 01 August 2007

Dendrimers destabilize proteins in a generation-dependent manner involving electrostatic interactions.

scientific article

Differential adsorption of variants of the Thermomyces lanuginosus lipase on a hydrophobic surface suggests a role for local flexibility

Directed evolution of barnase stability using proteolytic selection

scientific article

Divorcing folding from function: how acylation affects the membrane-perturbing properties of an antimicrobial peptide

scientific article published on 22 December 2009

Dual hydrolytic role for Pb(II) ions

scientific article published on 01 January 1994

Dynamic content exchange between liprotides

scientific article published on 5 December 2017

Early stages of amyloid fibril formation studied by liquid-state NMR: the peptide hormone glucagon

scientific article published on 13 March 2008

Effect of glycosylation on the extracellular domain of the Ag43 bacterial autotransporter: enhanced stability and reduced cellular aggregation

scientific article published in June 2008

Effect of protein–surfactant interactions on aggregation of β-lactoglobulin

scientific article published on 01 April 2011

Electrochemical analysis of the fibrillation of Parkinson's disease α-synuclein

scientific article published on February 2014

Electrostatics in the active site of an alpha-amylase

scientific article published on 01 September 1999

Elimination of a misfolded folding intermediate by a single point mutation

scientific article published in March 2004

Eurocin, a New Fungal Defensin: STRUCTURE, LIPID BINDING, AND ITS MODE OF ACTION

scientific article

Evolutionary insight into the functional amyloids of the pseudomonads

scientific article

Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation

scientific article

Fast mapping of global protein folding states by multivariate NMR: a GPS for proteins

scientific article

Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation

scientific article published on 12 September 2011

Flexibility of the Thrombin-activatable Fibrinolysis Inhibitor Pro-domain Enables Productive Binding of Protein Substrates

scientific article

Folding energetics and oligomerization of polytopic α-helical transmembrane proteins

scientific article published on 21 July 2014

Folding of Circular and Permuted Chymotrypsin Inhibitor 2: Retention of the Folding Nucleus ⬇️

scientific article published on June 2, 1998

Folding of DsbB in mixed micelles: a kinetic analysis of the stability of a bacterial membrane protein

scientific article published in July 2003

Folding of circular permutants with decreased contact order: general trend balanced by protein stability 1 1Edited by A. R. Fersht

Folding of outer membrane protein A in the anionic biosurfactant rhamnolipid

scientific article published on 13 April 2014

Folding of outer membrane proteins

scientific article

Formation of dynamic soluble surfactant-induced amyloid β peptide aggregation intermediates

scientific article published on 17 June 2013

Functional amyloid in Pseudomonas

scientific article

Functional amyloid: turning swords into plowshares

scientific article published on 17 October 2010

Global study of myoglobin-surfactant interactions

scientific article published on 11 December 2007

Glucagon amyloid-like fibril morphology is selected via morphology-dependent growth inhibition

scientific article published on 25 May 2007

Glucagon fibril polymorphism reflects differences in protofilament backbone structure

scientific article published on 12 February 2010

Glycolipid Biosurfactants Activate, Dimerize, and Stabilize Thermomyces lanuginosus Lipase in a pH-Dependent Fashion

scientific article published on 20 July 2017

Half a century of amyloids: past, present and future

scientific article published on 07 July 2020

Heparin binding induces a conformational change in pigment epithelium-derived factor

scientific article published on 2 January 2007

High stability and cooperative unfolding of α-synuclein oligomers

scientific article

How chain length and charge affect surfactant denaturation of acyl coenzyme A binding protein (ACBP).

scientific article published in October 2009

How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro

scientific article

Human Lysozyme Peptidase Resistance Is Perturbed by the Anionic Glycolipid Biosurfactant Rhamnolipid Produced by the Opportunistic Pathogen Pseudomonas aeruginosa

scientific article

Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp

scientific article

Hydrogen exchange in chymotrypsin inhibitor 2 probed by mutagenesis

scientific article published on 01 July 1997

Hydrogen exchange mass spectrometry as an analytical tool for the analysis of amyloid fibrillogenesis

scientific article published on April 2011

Impact of the antimicrobial peptide Novicidin on membrane structure and integrity

scientific article published on 28 January 2010

In vitro and in silico assessment of the developability of a designed monoclonal antibody library

scientific article published on 18 January 2019

In vitro association of fragments of a beta-sheet membrane protein.

scientific article

Influence of tunable external stimuli on the self-assembly of guanosine supramolecular nanostructures studied by atomic force microscope

scientific article

Interaction of a potyviral VPg with anionic phospholipid vesicles.

scientific article published on 2 October 2009

Interactions between folding factors and bacterial outer membrane proteins

scientific article

Interactions between misfolded protein oligomers and membranes: A central topic in neurodegenerative diseases?

scientific article

Investigating porcine pancreatic phospholipase A2 action on vesicles and supported planar bilayers using a quartz crystal microbalance with dissipation

article published in 2004

Kinetic partitioning between aggregation and vesicle permeabilization by modified ADan

scientific article

Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition

scientific article published on 2 September 2011

Liprotides assist in folding of outer membrane proteins

scientific article published in November 2017

Liprotides kill cancer cells by disrupting the plasma membrane

scientific article published on 9 November 2017

Long-Term-Stable Ether−Lipid vs Conventional Ester−Lipid Bicelles in Oriented Solid-State NMR: Altered Structural Information in Studies of Antimicrobial Peptides

scientific article published on 10 February 2011

Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation

scientific article

Low-resolution structures of OmpA⋅DDM protein-detergent complexes

scientific article

Mapping of unfolding states of integral helical membrane proteins by GPS-NMR and scattering techniques: TFE-induced unfolding of KcsA in DDM surfactant.

scientific article published on 14 April 2012

Mapping out the multistage fibrillation of glucagon

scientific article

Mapping the folding pathway of the transmembrane protein DsbB by protein engineering ⬇️

scientific article published on October 25, 2010

Mechanical stress affects glucagon fibrillation kinetics and fibril structure

scientific article published on 15 September 2011

Mechanistic Understanding of the Interactions between Nano-Objects with Different Surface Properties and α-Synuclein

scientific article published on 27 February 2019

Membrane Interactions of Novicidin, a Novel Antimicrobial Peptide: Phosphatidylglycerol Promotes Bilayer Insertion

Misfolding of a bacterial autotransporter

scientific article

Modeling proteasome dynamics in Parkinson's disease

scientific article published in May 2009

Modulation of S6 fibrillation by unfolding rates and gatekeeper residues

scientific article published in August 2004

Modulation of cutinase stability and structure by phospholipid detergents

scientific article published on 4 October 2007

Molecular dynamics study of ACBP denaturation in alkyl sulfates demonstrates possible pathways of unfolding through fused surfactant clusters

scientific article published on 01 December 2019

Movement of the position of the transition state in protein folding

scientific article published on 01 October 1995

Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization

scientific article

N for AsN - O for StrOcture? A strand-loop-strand motif for prokaryotic O-glycosylation

scientific article published in 2012

N- and C-Terminal Hydrophobic Patches Are Involved in Fibrillation of Glucagon†

article published in 2006

Nature and consequences of GroEL-protein interactions.

scientific article

Novicidin's membrane permeabilizing activity is driven by membrane partitioning but not by helicity: a biophysical study of the impact of lipid charge and cholesterol

scientific article published on 2 April 2013

Occupancy of Nonannular Lipid Binding Sites on KcsA Greatly Increases the Stability of the Tetrameric Protein

scientific article published on 01 June 2010

Off-pathway aggregation can inhibit fibrillation at high protein concentrations

scientific article published on 8 January 2013

Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity

scientific article published on 17 January 2019

Oligomers of α-synuclein: picking the culprit in the line-up

scientific article published in January 2014

OmpA can form folded and unfolded oligomers.

scientific article

PP3 forms stable tetrameric structures through hydrophobic interactions via the C-terminal amphipathic helix and undergoes reversible thermal dissociation and denaturation

scientific article published on 06 December 2011

Pardaxin permeabilizes vesicles more efficiently by pore formation than by disruption

scientific article

Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers

scientific article published on 26 October 2019

Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.

scientific article

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

scientific article

Protein aggregation: close encounters of the greasy kind

scientific article published in March 2015

Protein drug stability: a formulation challenge

scientific article

Protein fragments as models for events in protein folding pathways: Protein engineering analysis of the association of two complementary fragments of the barley chymotrypsin inhibitor 2 (CI-2)

article

Protein unfolding in detergents: effect of micelle structure, ionic strength, pH, and temperature

scientific article published on October 2002

Protein-fatty acid complexes: biochemistry, biophysics and function

scientific article published on 18 March 2013

Protein–surfactant interactions: A tale of many states ⬇️

scientific article published on March 22, 2011

Proteolytic activation of proteose peptone component 3 by release of a C-terminal peptide with antibacterial properties

scientific article

Proteomic changes in response to chromium(VI) toxicity in Pseudomonas aeruginosa

scientific article published on 30 November 2009

Quality control system response to stochastic growth of amyloid fibrils

scientific article published on 21 March 2013

Quantitating denaturation by formic acid: Imperfect repeats are essential to the stability of the functional amyloid protein FapC

scientific article published on 21 July 2020

Quantitative Use of Paramagnetic Relaxation Enhancements for Determining Orientations and Insertion Depths of Peptides in Micelles

scholarly article by Magnus Franzmann published in September 2009

Quartz crystal microbalance studies of multilayer glucagon fibrillation at the solid-liquid interface

scientific article

Quartz crystal microbalances as tools for probing protein-membrane interactions

scientific article published in January 2013

Reducing the Amyloidogenicity of Functional Amyloid Protein FapC Increases Its Ability To Inhibit α-Synuclein Fibrillation

scientific article published on 22 February 2019

Reduction in the amount of 8-hydroxy-2'-deoxyguanosine in the DNA of SV40-transformed human fibroblasts as compared with normal cells in culture

scientific article published in March 1993

Role of Charge and Hydrophobicity in Liprotide Formation: A Molecular Dynamics Study with Experimental Constraints

scientific article published on 20 November 2017

Role of elongation and secondary pathways in S6 amyloid fibril growth.

scientific article published on May 2012

SAXS Models of TGFBIp Reveal a Trimeric Structure and Show That the Overall Shape Is Not Affected by the Arg124His Mutation

article

SDS-Facilitated In vitro Formation of a Transmembrane B-Type Cytochrome Is Mediated by Changes in Local pH

SDS-induced fibrillation of alpha-synuclein: an alternative fibrillation pathway.

scientific article published on 9 June 2010

Salt-induced detour through compact regions of the protein folding landscape

scientific article published on October 1999

Scaffolded multimers of hIAPP 20–29 peptide fragments fibrillate faster and lead to different fibrils compared to the free hIAPP 20–29 peptide fragment

scientific article published on 15 August 2015

Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation

scientific article

Side-Chain Determinants of .beta.-Sheet Stability

scientific article published on 01 May 1995

Single versus parallel pathways of protein folding and fractional formation of structure in the transition state

scientific article published in October 1994

Soft interactions at nanoparticles alter protein function and conformation in a size dependent manner

scientific article published on 11 October 2011

Specific incorporation of kinetin into eukaryotic and prokaryotic transfer ribonucleic acid molecules.

scientific article

Spectroscopic evidence for the existence of an obligate pre-fibrillar oligomer during glucagon fibrillation

scientific article

Stability and structure of the membrane protein transporter Ffh is modulated by substrates and lipids

scientific article

Stabilization of the ribosomal protein S6 by trehalose is counterbalanced by the formation of a putative off-pathway species.

scientific article

Stable intermediates determine proteins' primary unfolding sites in the presence of surfactants

scientific article

Stop-and-go kinetics in amyloid fibrillation

Strategies to increase the reproducibility of protein fibrillization in plate reader assays

scientific article published on 10 February 2010

Structural Factors Contributing to the Hydrophobic Effect: The Partly Exposed Hydrophobic Minicore in Chymotrypsin Inhibitor 2

scientific article published on 01 October 1995

Structural background of cyclodextrin-protein interactions

scientific article published on December 2003

Structural basis for cyclodextrins' suppression of human growth hormone aggregation

scientific article

Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots

scientific article

Structure of the transition state for folding of a protein derived from experiment and simulation

scientific article

Structure of the transition state for the folding/unfolding of the barley chymotrypsin inhibitor 2 and its implications for mechanisms of protein folding.

scientific article published in October 1994

Sulfates dramatically stabilize a salt-dependent type of glucagon fibrils

scientific article published on 13 March 2006

Surfactant protein SP-B strongly modifies surface collapse of phospholipid vesicles: insights from a quartz crystal microbalance with dissipation.

scientific article

Synthesis of a ketomethylene isostere of the fibrillating peptide SNNFGAILSS.

scientific article published in October 2009

Tailoring thermal treatment to form liprotide complexes between oleic acid and different proteins

scientific article published on 25 March 2017

ThT 101: a primer on the use of thioflavin T to investigate amyloid formation

scientific article published on 10 April 2017

The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes

scientific article

The Spectral and Thermodynamic Properties of Staphylococcal Enterotoxin A, E, and Variants Suggest That Structural Modifications Are Important to Control Their Function

scientific article published in Journal of Biological Chemistry

The Stability of Transmembrane Helix Interactions Measured in a Biological Membrane

scientific article published on 13 March 2006

The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

article

The antimicrobial mechanism of action of epsilon-poly-l-lysine

scientific article

The changing face of glucagon fibrillation: structural polymorphism and conformational imprinting

scientific article published on 9 November 2005

The diversity of FtsY-lipid interactions

scientific article published on 01 July 2010

The effect of osmolytes on protein fibrillation

scientific article published on 21 March 2012

The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth

scientific article published on 04 May 2020

The influence of vesicle size and composition on alpha-synuclein structure and stability

scientific article published on April 2009

The interaction of equine lysozyme:oleic acid complexes with lipid membranes suggests a cargo off-loading mechanism

scientific article

The interactome of stabilized α-synuclein oligomers and neuronal proteins

scientific article published on 05 November 2019

The major allergen from birch tree pollen, Bet v 1, binds and permeabilizes membranes.

scientific article

The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands

scientific article

The natural, peptaibolic peptide SPF-5506-A4 adopts a β-bend spiral structure, shows low hemolytic activity and targets membranes through formation of large pores

scientific article published on 18 March 2015

The neuroendocrine protein 7B2 suppresses the aggregation of neurodegenerative disease-related proteins

scientific article

The role of decorated SDS micelles in sub-CMC protein denaturation and association.

scientific article

The role of membrane properties in Mistic folding and dimerisation

scientific article published on 22 November 2010

The role of proteins in biosilicification

scientific article published on October 2012

The role of protonation in protein fibrillation

scientific article published on 12 January 2010

The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.

scientific article published on 28 February 2014

Thermodynamics and mechanism of cutinase stabilization by trehalose.

scientific article published in June 2008

Thermodynamics of unfolding of an integral membrane protein in mixed micelles

scientific article

Transient aggregation and stable dimerization induced by introducing an Alzheimer sequence into a water-soluble protein

scientific article

Transient formation of nano-crystalline structures during fibrillation of an Abeta-like peptide

scientific article published in May 2004

Trehalose favors a cutinase compact intermediate off-folding pathway

scientific article

Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation

scientific article published on 22 March 2019

Unfolding of beta-sheet proteins in SDS

scientific article published on 9 March 2007

Unique identification of supramolecular structures in amyloid fibrils by solid-state NMR spectroscopy

scientific article

Using micellar mole fractions to assess membrane protein stability in mixed micelles

scientific article published in October 2005

Variant of the Thermomyces lanuginosus lipase with improved kinetic stability: A candidate for enzyme replacement therapy

scientific article published on 08 January 2013

Versatile interactions of the antimicrobial peptide novispirin with detergents and lipids

scientific article published in January 2006

We find them here, we find them there: functional bacterial amyloid.

scientific article published on March 2008

Widespread abundance of functional bacterial amyloid in mycolata and other gram-positive bacteria

scientific article published on 24 April 2009

Wildtype and A30P mutant alpha-synuclein form different fibril structures

scientific article

[Treatment of narcotic addiction--"fix" room causes less harm]. Interview by Jesper Berg.]

scientific article published in November 1997

beta-Sheet aggregation of kisspeptin-10 is stimulated by heparin but inhibited by amphiphiles

scientific article published in August 2010

p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies

scientific article

p25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry

scientific article published on 9 May 2005

p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy

scientific article

pH regulation of the kinetic stability of the lipase from Thermomyces lanuginosus

scientific article published on 26 December 2012

pH-dependent aggregation of cutinase is efficiently suppressed by 1,8-ANS

scientific article published on 01 December 2006

α-Lactalbumin is unfolded by all classes of surfactants but by different mechanisms

scientific article published on 17 October 2008

α-Synucleins from Animal Species Show Low Fibrillation Propensities and Weak Oligomer Membrane Disruption

scientific article published on 15 August 2018

α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities

scientific article published on 02 August 2019

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