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List of works by Erich Gulbins

A Novel Mechanism Involved in the Pathogenesis of Graves Ophthalmopathy (GO): Clathrin Is a Possible Targeting Molecule for Inhibiting Local Immune Response in the Orbit ⬇️

scientific article published on September 14, 2011

A central role for the acid sphingomyelinase/ceramide system in neurogenesis and major depression

scientific article

A novel potassium channel in lymphocyte mitochondria

scientific article

A sphingolipid mechanism for behavioral extinction

scientific article published on 20 January 2016

Abstract 121: Novel Antibiotic Thin Films Prevent Surgical Implant Infections.

scientific article published in April 2018

Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency.

scientific article published on 4 November 2009

Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death ⬇️

scientific article published on November 13, 2010

Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development

scientific article published on 12 August 2016

Acid Sphingomyelinase Inhibition Prevents Hemolysis During Erythrocyte Storage

scientific article published on 29 June 2016

Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation

scientific article published on January 2017

Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease

scientific article published on 12 March 2020

Acid ceramidase rescues cystic fibrosis mice from pulmonary infections

scientific article published on 02 November 2020

Acid sphingomyelinase

scientific article published on January 2013

Acid sphingomyelinase amplifies redox signaling in Pseudomonas aeruginosa-induced macrophage apoptosis

scientific article

Acid sphingomyelinase and its redox amplification in formation of lipid raft redox signaling platforms in endothelial cells

scientific article

Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis

scientific article

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage.

scientific article published on 4 August 2008

Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis

scientific article published on 25 January 2015

Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis

scientific article

Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae

scientific article published on August 2000

Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation

scientific article

Acid sphingomyelinase-derived ceramide signaling in apoptosis

scientific article

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

scientific article (publication date: 16 June 2013)

Actinomycin D-induced apoptosis involves the potassium channel Kv1.3.

scientific article published on July 2002

Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis

scientific article published on 27 January 2014

Activation of the Permeability Transition Pore by Bax via Inhibition of the Mitochondrial BK Channel ⬇️

scientific article published on January 1, 2011

Activity of Secretory Sphingomyelinase Is Increased in Plasma of Alcohol-Dependent Patients

Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent.

scientific article

Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection

scientific article published on 29 March 2010

Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients

scientific article published on 17 August 2015

Alveolar inflammation in cystic fibrosis

scientific article

Amitriptyline Usage Exacerbates the Immune Suppression Following Burn Injury

scientific article

Amyloid induced suicidal erythrocyte death

scientific article published on 01 January 2007

An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1.

scientific article

Annexin II is a novel receptor for Pseudomonas aeruginosa

scientific article published in February 2005

Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide

scientific article published on 23 July 2018

Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice

scientific article published on 03 February 2020

Bioactive Lipids and Redox Signaling: Molecular Mechanism and Disease Pathogenesis

scientific article published on 14 December 2017

Biological aspects of ceramide-enriched membrane domains

scientific article published on 31 March 2007

Blockade of Experimental Multiple Sclerosis by Inhibition of the Acid Sphingomyelinase/Ceramide System

scientific article published on 6 November 2017

Burn injury influences the T cell homeostasis in a butyrate-acid sphingomyelinase dependent manner

scientific article published on 26 December 2016

C2-ceramide signaling in glioma cells: synergistic enhancement of CD95-mediated, caspase-dependent apoptosis

scientific article

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release

scientific article published in July 2001

CD66-mediated phagocytosis of Opa52 Neisseria gonorrhoeae requires a Src-like tyrosine kinase- and Rac1-dependent signalling pathway.

scientific article published on January 1998

CD95 Signaling via Ceramide-rich Membrane Rafts

scientific article published in Journal of Biological Chemistry

CD95 rapidly clusters in cells of diverse origins

scientific article

CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa

scientific article

CD95/CD95 ligand-mediated counterattack does not block T cell cytotoxicity

scientific article

CFTR-dependent susceptibility of the cystic fibrosis-host to Pseudomonas aeruginosa ⬇️

scientific article published on October 14, 2010

Ca2+-activated K channel of the BK-type in the inner mitochondrial membrane of a human glioma cell line

scientific article published on April 1999

Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase: implications for uptake

scientific article published on 08 July 2010

Cell volume and the regulation of apoptotic cell death

scientific article published in September 2004

Cell volume in the regulation of cell proliferation and apoptotic cell death

scientific article

Cell volume regulatory ion channels in cell proliferation and cell death

scientific article published on January 2007

Cellular stimulation via CD95 involves activation of phospho-inositide-3-kinase ⬇️

scientific article published on March 1, 1998

Cellular taurine release triggered by stimulation of the Fas(CD95) receptor in Jurkat lymphocytes ⬇️

scientific article published on August 1, 1998

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

scientific article

Ceramide and cell death receptor clustering

scientific article

Ceramide and sphingosine in pulmonary infections

scientific article published on June 2015

Ceramide enables fas to cap and kill

scientific article published on 3 April 2001

Ceramide formation as a target in beta-cell survival and function ⬇️

scientific article published on 02 June 2011

Ceramide in Cystic Fibrosis ⬇️

scientific article published on January 1, 2013

Ceramide in Pseudomonas aeruginosa infections and cystic fibrosis

scientific article published on 18 May 2010

Ceramide in bacterial infections and cystic fibrosis

scientific article

Ceramide in chemotherapy of tumors

scientific article published on September 2011

Ceramide in suicidal death of erythrocytes

scientific article published on 18 May 2010

Ceramide in the regulation of eryptosis, the suicidal erythrocyte death

scientific article published in May 2015

Ceramide inPseudomonas aeruginosa infections

Ceramide inhibits the potassium channel Kv1.3 by the formation of membrane platforms

scientific article published in June 2003

Ceramide mediates lung fibrosis in cystic fibrosis ⬇️

scientific article published on March 21, 2013

Ceramide metabolism determines glioma cell resistance to chemotherapy

scientific article

Ceramide, membrane rafts and infections

scientific article published on 7 April 2004

Ceramide-enriched membrane domains

scientific article

Ceramide-enriched membrane domains in infectious biology and development

scientific article published on January 2008

Ceramide-enriched membrane domains--structure and function

scientific article published on 22 August 2008

Ceramide-induced cell death in malignant cells

scientific article published on 18 March 2008

Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases

scientific article published on July 1997

Ceramide-mediated clustering is required for CD95-DISC formation

Ceramide: A Novel Player in Reactive Oxygen Species-Induced Signaling?

article

Ceramide: physiological and pathophysiological aspects

scientific article published on 11 April 2007

Characterization of acid sphingomyelinase activity in human cerebrospinal fluid

scientific article

Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes

scientific article

Chemosensitivity of human malignant glioma: modulation by p53 gene transfer

scientific article published on August 1, 1998

Chronic Psychosocial Stress in Mice Is Associated With Increased Acid Sphingomyelinase Activity in Liver and Serum and With Hepatic C16:0-Ceramide Accumulation

Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells

scientific article published on 01 August 2007

Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia.

scientific article published on 21 February 2013

Clustering of CD40 ligand is required to form a functional contact with CD40.

scientific article

Conjugated bilirubin triggers anemia by inducing erythrocyte death

scientific article

Contribution of p62 to Phenotype Transition of Coronary Arterial Myocytes with Defective Autophagy

scientific article published on 3 February 2017

Contribution of voltage-gated potassium channels to the regulation of apoptosis.

scientific article published on 25 January 2010

Correction for Saporito et al., Oribatid mites as a major dietary source for alkaloids in poison frogs

scholarly article

Correction: Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation

scientific article published on 30 December 2015

Crosstalk Between Sphingomyelinases and Reactive Oxygen Species in Mycobacterial Infection

scientific article published on 9 March 2017

Cystic fibrosis and innate immunity: how chloride channel mutations provoke lung disease

scientific article published on 02 December 2008

DC-SIGN Mediated Sphingomyelinase-Activation and Ceramide Generation Is Essential for Enhancement of Viral Uptake in Dendritic Cells ⬇️

scientific article published on February 17, 2011

DNA quantification and fragmentation in sputum after inhalation of recombinant human deoxyribonuclease

scientific article published on 25 July 2008

Defective autophagosome trafficking contributes to impaired autophagic flux in coronary arterial myocytes lacking CD38 gene

scientific article published on 20 January 2014

Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells

scientific article

Doxorubicin enhances TRAIL-induced cell death via ceramide-enriched membrane platforms

article by Claudia Alexandra Dumitru et al published 23 May 2007 in Apoptosis

Effect of astroglial cell swelling on pH of acidic intracellular compartments

scientific article published on December 1996

Effect of bacterial peptidoglycan on erythrocyte death and adhesion to endothelial cells ⬇️

scientific article published on 05 March 2013

Effects of green tea compound epigallocatechin-3-gallate against Stenotrophomonas maltophilia infection and biofilm

scientific article

Endocytosis of Red Blood Cell Microparticles by Pulmonary Endothelial Cells is Mediated By Rab5.

scientific article published in March 2018

Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis

scientific article

Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice

scientific article published on 2 November 2014

Enhanced eryptosis of erythrocytes from gene-targeted mice lacking annexin A7.

scientific article published on 20 May 2010

Enhancement of endothelial permeability by free fatty acid through lysosomal cathepsin B-mediated Nlrp3 inflammasome activation

scientific article published on 28 September 2016

Eryptosis triggered by bismuth

scientific article

Eryptosis, a window to systemic disease

scientific article published on 09 December 2008

Evidence for a novel function of the CD40 ligand as a signalling molecule in T‐lymphocytes ⬇️

scientific article published on November 17, 1997

Examination of Orbital Tissues in Murine Models of Graves' Disease Reveals Expression of UCP-1 and the TSHR in Retrobulbar Adipose Tissues ⬇️

scientific article published on 05 February 2013

Fas- or Ceramide-induced Apoptosis Is Mediated by a Rac1-regulated Activation of Jun N-terminal Kinase/p38 Kinases and GADD153 ⬇️

scientific article published on August 29, 1997

Fas-induced apoptosis is mediated by activation of a Ras and Rac protein-regulated signaling pathway

scientific article published on 01 October 1996

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs) ⬇️

scientific article published on January 1, 2013

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications

scientific article

Functional implications of novel human acid sphingomyelinase splice variants

scientific article

Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway

scientific article

Glucosylceramide Critically Contributes to the Host Defense of Cystic Fibrosis Lungs

scientific article published on 6 March 2017

Glycosylation processing inhibition by castanospermine prevents experimental autoimmune encephalomyelitis by interference with IL-2 receptor signal transduction

scientific article published in November 2002

Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate

scientific article published on 5 August 2015

High activity of acid sphingomyelinase in major depression

scientific article

Highlight: molecular medicine of sphingolipids

scientific article

Highlight: sphingolipids - signals and disease

scientific article published on 01 November 2008

Highlights of a workshop to discuss targeting inflammation in cystic fibrosis

scientific article

Highly sensitive isotope-dilution liquid-chromatography-electrospray ionization-tandem-mass spectrometry approach to study the drug-mediated modulation of dopamine and serotonin levels in Caenorhabditis elegans.

scientific article

Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts

scientific article

Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model

scientific article

Identification of novel functional inhibitors of acid sphingomyelinase

scientific article published in 2011

Implication of CD38 gene in autophagic degradation of collagen I in mouse coronary arterial myocytes.

scientific article

Increased acid sphingomyelinase activity in peripheral blood cells of acutely intoxicated patients with alcohol dependence

scientific article published on 23 October 2009

Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.

scientific article

Induction of membrane ceramides: a novel strategy to interfere with T lymphocyte cytoskeletal reorganisation in viral immunosuppression

scientific article

Infections with Human Rhinovirus Induce the Formation of Distinct Functional Membrane Domains

Influence of amitriptyline on eryptosis, parasitemia and survival of Plasmodium berghei-infected mice

scientific article

Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells

scientific article

Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression

scientific article published on 19 December 2015

Inhibition of Fas-Induced Apoptotic Cell Death by Osmotic Cell Shrinkage ⬇️

scientific article published on July 18, 1997

Inhibition of acid sphingomyelinase by tricyclic antidepressants and analogons

scientific article

Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice

scientific article

Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis

scientific article published on January 2016

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

scientific article published on 11 April 2012

Inhibitory effects of oxidants on n-type K+ channels in T lymphocytes and Xenopus oocytes

scientific article published in March 1997

Intracellular ion channels and cancer

scientific article

Intracellular mechanisms of L-selectin induced capping

scientific article published on April 1999

Invariant natural killer T (iNKT) cells prevent autoimmunity, but induce pulmonary inflammation in cystic fibrosis

scientific article published on 16 June 2014

Invasion of human epithelial cells by Pseudomonas aeruginosa involves src-like tyrosine kinases p60Src and p59Fyn.

scientific article published on January 2001

Ion Channels, Cell Volume, and Apoptotic Cell Death

scientific article published on 01 January 1998

Ion channels and cell volume in regulation of cell proliferation and apoptotic cell death.

scientific article published on January 2006

Ion channels and membrane rafts in apoptosis.

scientific article published on 8 April 2004

Ischemia/Reperfusion Injury Alters Sphingolipid Metabolism in the Gut.

scientific article published on 8 September 2016

It takes a CAD to kill a tumor cell with a LMP.

scientific article

Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections ⬇️

scientific article published on February 6, 2011

L-Selectin Stimulates the Neutral Sphingomyelinase and Induces Release of Ceramide ⬇️

scientific article published on August 25, 1998

L-selectin activates the Ras pathway via the tyrosine kinase p56lck

scientific article

L-selectin regulates actin polymerisation via activation of the small G-protein Rac2.

scientific article published on February 1997

Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis

scientific article

Lipid raft clustering and redox signaling platform formation in coronary arterial endothelial cells

scientific article

Lipid rafts and redox signaling

scientific article published on September 2007

Lipids control mucus production in cystic fibrosis

scientific article published in March 2010

Lipids in cystic fibrosis

scientific article published on August 2011

Lipids in psychiatric disorders and preventive medicine

scientific article

Lipoxygenase inhibitors block CD95 ligand-mediated apoptosis of human malignant glioma cells.

scientific article published in June 1997

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide

scientific journal article

Long-Term Pulmonal Therapy of Cystic Fibrosis-Patients with Amitriptyline

scientific article published on 11 July 2016

Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier function and increases susceptibility to microvascular damage from cigarette smoke

scientific article published on June 2014

Lysophosphatidic Acid Inhibits Insulin Signaling in Primary Rat Hepatocytes via the LPA3 Receptor Subtype and is Increased in Obesity

scientific article

Lysosomal ceramide mediates gemcitabine-induced death of glioma cells

scientific article published on 10 September 2009

Mechanisms of Staphylococcus aureus induced apoptosis of human endothelial cells

scientific article

Melanoma cell metastasis via P-selectin-mediated activation of acid sphingomyelinase in platelets

scientific article published on 15 October 2016

Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System

scientific article published on 11 July 2016

Membrane rafts in host-pathogen interactions

scientific article published on 8 August 2006

Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation

scientific article

Mitochondrial ion channels as oncological targets

scientific article published on 27 January 2014

Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes

scientific article

Molecular analysis of Ras activation by tyrosine phosphorylated Vav

scientific article published on 01 December 1995

Molecular mechanisms of bacteria induced apoptosis.

scientific article

Molecular mechanisms of ceramide-mediated CD95 clustering

scientific article published in June 2001

Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes.

scientific article

Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine

scientific article published on 17 October 2017

Niemann–Pick Disease versus acid sphingomyelinase deficiency

scientific article published on 01 January 2001

Novel channels of the inner mitochondrial membrane

scientific article

Overexpression of acid sphingomyelinase sensitizes glioma cells to chemotherapy

scientific article

Oxidative Stress Triggers Ca2+-Dependent Lysosome Trafficking and Activation of Acid Sphingomyelinase ⬇️

scientific article published on August 10, 2012

PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide.

scientific article

Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2018

Pharmacological targeting of ion channels for cancer therapy: In vivo evidences

scientific article

Phospholipase A2 functions in Pseudomonas aeruginosa-induced apoptosis

scientific article published on February 2006

Physiological and pathophysiological aspects of ceramide

scientific article

Physiology of potassium channels in the inner membrane of mitochondria

scientific article

Plasma membrane ion channels in suicidal cell death

scientific article published on 22 January 2007

Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase

scientific article

Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases

scientific article published on April 2001

Pulmonary infection of cystic fibrosis mice with Staphylococcus aureus requires expression of α-toxin

scientific article published in April 2018

Quantitative Determination of Ceramide Molecular Species in Dendritic Cells

scientific article published on 15 September 2016

Raft ceramide in molecular medicine

scientific article published on October 2003

Reactive oxygen species limit neutrophil life span by activating death receptor signaling

scientific article published on 6 July 2004

Regulation of Arthritis Severity by the Acid Sphingomyelinase

scientific article

Regulation of Neuronal Stem Cell Proliferation in the Hippocampus by Endothelial Ceramide

scientific article published on August 2016

Regulation of Staphylococcus aureus Infection of Macrophages by CD44, Reactive Oxygen Species, and Acid Sphingomyelinase

scientific article

Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes

scientific article published on October 2013

Regulation of death receptor signaling and apoptosis by ceramide

scientific article

Regulation of hematogenous tumor metastasis by acid sphingomyelinase

scientific article

Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1

scientific article published on 01 July 2006

Regulation of the inflammasome by ceramide in cystic fibrosis lungs.

scientific article

Rhinoviral Infections Activate p38MAP-Kinases Via Membrane Rafts and RhoA

Rhinoviruses infect human epithelial cells via ceramide-enriched membrane platforms

scientific article

Role of Acid Sphingomyelinase in the Regulation of Social Behavior and Memory

scientific article

Role of Acid Sphingomyelinase-Induced Signaling in Melanoma Cells for Hematogenous Tumor Metastasis

scientific article published on 8 January 2016

Role of CD95 in pulmonary inflammation and infection in cystic fibrosis

scientific article published on 01 September 2012

Role of Janus-Kinases in Major Depressive Disorder

scientific article published on 3 August 2016

Role of Kinase Suppressor of Ras-1 in Lipopolysaccharide-Induced Acute Lung Injury ⬇️

scientific article published on August 28, 2012

Role of Kv1.3 mitochondrial potassium channel in apoptotic signalling in lymphocytes.

scientific article

Role of acid sphingomyelinase in the regulation of mast cell function

scientific article published on 01 January 2014

Role of acidic sphingomyelinase in thymol-mediated dendritic cell death

scientific article published on December 2010

Role of mitochondria in apoptosis

scientific article

Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: the role of COX-1 and MRP.

scientific article published in June 1999

Sex-dependent decrease of sphingomyelinase activity during alcohol withdrawal treatment

scientific article published on 16 June 2014

Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis.

scientific article published on October 2010

Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa

scientific article

Sphingolipids and Innate Immunity: A New Approach to Infection in the Post-Antibiotic Era?

scientific article published on 02 October 2018

Sphingolipids as targets for inhalation treatment of cystic fibrosis

scientific article

Sphingolipids in Major Depression

scientific article published on 19 December 2015

Sphingolipids in liver injury, repair and regeneration

scientific article published on June 2015

Sphingolipids in the lungs.

scientific article published on 28 August 2008

Sphingomyelinase dependent apoptosis of dendritic cells following treatment with amyloid peptides

scientific article published on 8 January 2010

Sphingomyelinase-induced adhesion of eryptotic erythrocytes to endothelial cells ⬇️

scientific article published on 05 September 2012

Sphingosine rescues aged mice from pulmonary pseudomonas infection

scientific article published on 25 July 2017

Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic

scientific article published on 21 March 2017

Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide

scientific article published on 30 October 2017

Staphylococcus aureus Survives in Cystic Fibrosis Macrophages, Forming a Reservoir for Chronic Pneumonia

scientific article published on 13 March 2017

Staphylococcus aureus α-Toxin Induces Inflammatory Cytokines via Lysosomal Acid Sphingomyelinase and Ceramides

scientific article

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.

scientific article published on November 1999

Stimulation of Erythrocyte Phosphatidylserine Exposure by Paclitaxel

Stimulation of TK1 Lymphoma Cells via α4β7Integrin Results in Activation of src-Tyrosine- and MAP-Kinases ⬇️

scientific article published on October 9, 1997

Studying Mechanisms of Eryptosis

scientific article

Suicidal death of erythrocytes due to selenium-compounds

scientific article

Suicidal erythrocyte death in sepsis

scientific article published on 16 December 2006

Suicide for survival--death of infected erythrocytes as a host mechanism to survive malaria

scientific article

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

scientific article

TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx

scientific article

Targeting a mitochondrial potassium channel to fight cancer

scientific article

Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells

scientific article published in September 2017

Targeting the ceramide system in cancer ⬇️

scientific article published on July 23, 2011

The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways

scientific article

The CD40 Ligand Directly Activates T-Lymphocytes via Tyrosine Phosphorylation Dependent PKC Activation ⬇️

scientific article published on 01 October 1997

The CD40‐ligand stimulates T‐lymphocytes via the neutral sphingomyelinase : A novel function of the CD40‐ligand as signalling molecule ⬇️

scientific article published on September 8, 1997

The ceramide system as a novel antidepressant target.

scientific article

The common acid sphingomyelinase polymorphism p.G508R is associated with self-reported allergy.

scientific article published on 16 June 2014

The nitroso-donor S-nitroso-cysteine regulates IsK expressed in Xenopus oocytes via a c-GMP independent mechanism

scientific article

The role of ceramide in major depressive disorder

scientific article

The role of sphingolipids and ceramide in pulmonary inflammation in cystic fibrosis

scientific article

The role of sphingolipids in psychoactive drug use and addiction

scientific article published on 10 January 2018

The sphingosine 1-phosphate breakdown product, (2E)-hexadecenal, forms protein adducts and glutathione conjugates in vitro

scientific article published on 06 June 2017

The transmembranous domain of CD40 determines CD40 partitioning into lipid rafts

scientific article published on 01 January 2003

The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation.

scientific article

The tyrosine kinase p56lck mediates activation of swelling-induced chloride channels in lymphocytes

scientific article published on April 1998

The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response

scientific article published on 03 January 2008

Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis.

scientific article published in July 2009

Therapy of CF-patients with amitriptyline and placebo--a randomised, double-blind, placebo-controlled phase IIb multicenter, cohort-study

scientific article published on 02 April 2013

Triggering of dendritic cell apoptosis by xanthohumol

scientific article published in July 2010

Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes.

scientific article published on May 1998

Tyrosine kinases open lymphocyte chloride channels.

scientific article

[Founding a "Lymph Node Metastasis" Study Group at the West German Tumor Center (WTZE)]

scientific article published on 01 September 2007

[Identification of the molecular bases of metastasis for the development of new therapy strategies of metastatic prostate carcinoma]

scientific article published on 01 September 2007

[Molecular aspects of lymph node metastasis]

scientific article published on 01 January 2009

[Molecular biology approach to explain lymphatic metastasis]

scientific article published on 01 June 2005

[Proapoptotic antibodies as new therapeutic agents for tumor treatment]

scientific article published on 01 September 2007

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