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List of works by Annette Kopp-Schneider

"The good into the pot, the bad into the crop!"--a new technology to free stem cells from feeder cells

scientific article published on 21 November 2008

"ToxRTool", a new tool to assess the reliability of toxicological data

scientific article

"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.

scientific article published on 29 April 2016

18F-FDG PET/CT longitudinal studies in patients with advanced metastatic melanoma for response evaluation of combination treatment with vemurafenib and ipilimumab

scientific article published on 01 April 2019

4D-CT-based target volume definition in stereotactic radiotherapy of lung tumours: Comparison with a conventional technique using individual margins

article by Holger Hof et al published December 2009 in Radiotherapy and Oncology

68Ga-PSMA PET/CT in the evaluation of bone metastases in prostate cancer

scientific article

99mTc-MAG3 Diuretic Renography: Intra- and Inter-Observer Repeatability in the Assessment of Renal Function

scientific article published on 17 September 2020

A decision-theoretic approach to Bayesian clinical trial design and evaluation of robustness to prior-data conflict

scientific article published on 31 July 2020

A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events

scientific article published in March 1998

A model for hepatocarcinogenesis with clonal expansion of three successive phenotypes of preneoplastic cells

scientific article published in December 2000

A multistage model of carcinogenesis incorporating DNA damage and repair

scientific article published in September 1991

A perivascular niche in the bone marrow hosts quiescent and proliferating tumorigenic colorectal cancer cells

scientific article published on 19 February 2020

A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy

scientific article

A stem cell model for carcinogenesis

scientific article published on April 1994

A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice

scientific article published on 13 September 2019

Absolute number of new lesions on 18F-FDG PET/CT is more predictive of clinical response than SUV changes in metastatic melanoma patients receiving ipilimumab

scientific article published on 10 November 2017

Accuracy and variability of semiautomatic centerline analysis versus manual aortic measurement techniques for TEVAR.

scientific article published on 11 January 2013

Accuracy of MRI with an endorectal coil for staging endometrial cancer

Addressing small sample size bias in multiple-biomarker trials: Inclusion of biomarker-negative patients and Firth correction

scientific article published in August 2017

Adjuvant Therapy with Edrecolomab versus Observation in Stage II Colon Cancer: A Multicenter Randomized Phase III Study*

Adjuvant chemotherapy in stage III colon cancer with 5-fluorouracil and levamisole versus 5-fluorouracil and leucovorin

scientific article published in October 2002

An R-Shiny application to calculate optimal designs for single substance and interaction trials in dose response experiments

scientific article published on 21 November 2020

An adaptive group sequential phase II design to compare treatments for survival endpoints in rare patient entities

scientific article published in January 2012

Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro

scientific article published on 8 February 2008

Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study

scientific article

Application of a color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment

scientific article published on 17 April 2006

Application of a two-phenotype color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment

scientific article published on 4 January 2010

Assessment of glucose metabolism and cellular proliferation in multiple myeloma: a first report on combined 18F-FDG and 18F-FLT PET/CT imaging.

scientific article published on 10 April 2018

Assessment of morphological MRI for pulmonary changes in cystic fibrosis (CF) patients: comparison to thin-section CT and chest x-ray

scientific article published in October 2007

Assessment of thoracic aortic conformational changes by four-dimensional computed tomography angiography in patients with chronic aortic dissection type b

Associations of diet and lifestyle factors with common volatile organic compounds in exhaled breath of average-risk individuals

scientific article published on 01 March 2019

Author Correction: Methods and open-source toolkit for analyzing and visualizing challenge results

correction of a scholarly article

Author Correction: Why rankings of biomedical image analysis competitions should be interpreted with care

scientific article published in Nature Communications

BIAS: Transparent reporting of biomedical image analysis challenges

scientific article published on 21 August 2020

Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment

scientific article published on March 2013

Biostatistical evaluation of focal hepatic preneoplasia

scientific article published in January 2003

Birth and death/differentiation rates of papillomas in mouse skin ⬇️

scientific article published on June 1, 1992

C4.4A as a candidate marker in the diagnosis of colorectal cancer

scientific article

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

scientific article published on 8 February 2016

Calculating tumor incidence rates in stochastic models of carcinogenesis

scientific article

Can 18F-NaF PET/CT before Autologous Stem Cell Transplantation Predict Survival in Multiple Myeloma?

scientific article published on 23 May 2020

Can benign lymphoid tissue changes in 18F-FDG PET/CT predict response to immunotherapy in metastatic melanoma?

scientific article published on 26 November 2018

Carcinogenesis models for risk assessment ⬇️

scientific article published on December 1, 1997

Carcinoma formation in NMRI mouse skin painting studies is a process suggesting greater than two stages

scientific article published on January 1995

Cell proliferation and cell death (apoptosis) in hepatic preneoplasia and neoplasia are closely related to phenotypic cellular diversity and instability.

scientific article published in November 1994

Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures

scientific article published on 17 March 2015

Changes of prostate gland volume with and without androgen deprivation after intensity modulated radiotherapy - A follow-up study

scientific article published on 22 October 2008

Chemosensitivity-directed therapy compared to dacarbazine in chemo-naive advanced metastatic melanoma: a multicenter randomized phase-3 DeCOG trial

scientific article published on 27 June 2017

Clinical phase I/II trial to investigate neoadjuvant intensity-modulated short term radiation therapy (5 × 5 Gy) and intraoperative radiation therapy (15 Gy) in patients with primarily resectable pancreatic cancer - NEOPANC

scientific article published on 23 March 2012

Clinical trial protocol of the ASTER trial: a double-blind, randomized, placebo-controlled phase III trial evaluating the use of acetylsalicylic acid (ASA) for enhanced early detection of colorectal neoplasms

Clustering of samples and variables with mixed-type data.

scientific article published on 28 November 2017

Comments on "Incorporating historical two-arm data in clinical trials with binary outcome: A practical approach" by Manuel Feißt, Johannes Krisam and Meinhard Kieser

scientific article published on 02 September 2020

Comparative analysis of eight cytotoxicity assays evaluated within the ACuteTox Project

scientific article published on 23 August 2012

Comparison of PET/CT and PET/MRI hybrid systems using a 68Ga-labelled PSMA ligand for the diagnosis of recurrent prostate cancer: initial experience

scientific article published on 19 December 2013

Comparison of hybrid (68)Ga-PSMA PET/MRI and (68)Ga-PSMA PET/CT in the evaluation of lymph node and bone metastases of prostate cancer

scientific article published on 28 October 2015

Comparison of mode of action of four hepatocarcinogens: a model-based approach

scientific article published on 17 July 2007

Comparison of software tools to improve the detection of carcinogen induced changes in the rat liver proteome by analyzing SELDI-TOF-MS spectra

scientific article published in February 2006

Concordance analysis: part 16 of a series on evaluation of scientific publications

scientific article

Correction: E6 and E7 from Beta Hpv38 Cooperate with Ultraviolet Light in the Development of Actinic Keratosis-Like Lesions and Squamous Cell Carcinoma in Mice

scientific article published on 28 October 2016

Corrigendum: Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases.

scientific article published on 4 June 2019

Data management in large-scale collaborative toxicity studies: how to file experimental data for automated statistical analysis

scientific article

Design of a testing strategy using non-animal based test methods: lessons learnt from the ACuteTox project

scientific article published on 23 August 2012

Deviation from additivity in mixture toxicity: relevance of nonlinear dose-response relationships and cell line differences in genotoxicity assays with combinations of chemical mutagens and gamma-radiation

scientific article

Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA).

scientific article published on 03 March 2016

Differential signatures of protein expression in marmoset liver and thymus induced by single-dose TCDD treatment

scientific article published in January 2005

Diffusion-weighted imaging in rectal carcinoma patients without and after chemoradiotherapy: A comparative study with histology

article

Dissecting and modeling the emergent murine TEC compartment during ontogeny.

scientific article published on 25 April 2017

Distinguishing between models of carcinogenesis: the role of clonal expansion

scientific article published in October 1991

Drawing statistical conclusions from experiments with multiple quantitative measurements per subject

scientific article published on 20 August 2020

E6 and E7 from beta HPV38 cooperate with ultraviolet light in the development of actinic keratosis-like lesions and squamous cell carcinoma in mice

scientific article published in July 2011

E6/E7 expression of human papillomavirus type 20 (HPV-20) and HPV-27 influences proliferation and differentiation of the skin in UV-irradiated SKH-hr1 transgenic mice

scientific article

Effect of a Single Aspirin Dose Prior to Fecal Immunochemical Testing on Test Sensitivity for Detecting Advanced Colorectal Neoplasms: A Randomized Clinical Trial

scientific article published on 01 May 2019

Effects of low doses of N-nitrosomorpholine on the development of early stages of hepatocarcinogenesis.

scientific article

Efficacy and toxicity of chemoradiation in patients with anal cancer--a retrospective analysis

scientific article

Embryonic stem cell transplantation after experimental traumatic brain injury dramatically improves neurological outcome, but may cause tumors

scientific article published on January 2007

Epstein-Barr virus particles induce centrosome amplification and chromosomal instability

scientific article

Epstein-Barr virus stimulates torque teno virus replication: a possible relationship to multiple sclerosis

scientific article (publication date: 2012)

Equilibrium radionuclide angiography: Intra- and inter-observer repeatability and reproducibility in the assessment of cardiac systolic and diastolic function

scientific article published on 05 August 2019

Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity

scientific article

Evaluation of the ESUR PI-RADS scoring system for multiparametric MRI of the prostate with targeted MR/TRUS fusion-guided biopsy at 3.0 Tesla

scientific article published on 3 October 2013

Exploiting the potential of unlabeled endoscopic video data with self-supervised learning

scientific article published on 27 April 2018

Exploratory identification of predictive biomarkers in randomized trials with normal endpoints

scientific article published on 21 December 2019

Expression of the thrombin receptor PAR-1 correlates with tumour cell differentiation of pancreatic adenocarcinoma in vitro

scientific article

Extract derived from rat brains in the acute phase following traumatic brain injury impairs survival of undifferentiated stem cells and induces rapid differentiation of surviving cells

scientific article published in January 2010

Fine tuning of the threshold of T cell selection by the Nck adapters.

scientific article

GOLD stage predicts thoracic aortic calcifications in patients with COPD

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

scientific article published on 13 January 2014

Glossopharyngeal Insufflation and Pulmonary Hemodynamics in Elite Breath Hold Divers

HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth

scientific article published on 22 April 2010

Hepadnaviral hepatocarcinogenesis: in situ visualization of viral antigens, cytoplasmic compartmentation, enzymic patterns, and cellular proliferation in preneoplastic hepatocellular lineages in woodchucks

scientific article published on 01 October 2000

Heterogeneous treatment effects in stratified clinical trials with time-to-event endpoints

scientific article published on 6 March 2017

High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from individuals with combined CYP1A1 MspI/Msp-GSTM1*0/*0 genotypes

High-resolution phase-contrast MRI of aortic and pulmonary blood flow during rest and physical exercise using a MRI compatible bicycle ergometer

Histone deacetylase 8 in neuroblastoma tumorigenesis

scientific article

How to Exploit Weaknesses in Biomedical Challenge Design and Organization

How to evaluate agreement between quantitative measurements

scientific article published on 25 September 2019

INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies

scientific article published on 05 June 2020

Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization

scientific article

Incorporating phenotype-dependent growth rates into the color-shift model for preneoplastic hepatocellular lesions

scientific article published in September 2002

Increased incidence of squamous cell carcinomas in Mastomys natalensis papillomavirus E6 transgenic mice during two-stage skin carcinogenesis

scientific article published on May 2004

Intrinsic gating for small-animal computed tomography: a robust ECG-less paradigm for deriving cardiac phase information and functional imaging

scientific article published in November 2008

Investigating the formation and growth of alpha-particle radiation-induced foci of altered hepatocytes: a model-based approach.

scientific article

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

scientific article published on 02 October 2018

Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2.

scientific article published on September 1998

Longitudinal studies of the 18F-FDG kinetics after ipilimumab treatment in metastatic melanoma patients based on dynamic FDG PET/CT

scientific article published on 05 June 2018

MRI Detects Chronic Rhinosinusitis in Infants and Preschool Children with Cystic Fibrosis

scientific article published on 06 March 2020

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma

scientific article published on 26 April 2013

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

scientific article published on 27 August 2016

Magnetic Resonance Imaging Detects Changes in Structure and Perfusion, and Response to Therapy in Early Cystic Fibrosis Lung Disease

article

Magnetic resonance-compatible-spirometry: principle, technical evaluation and application

Malignant progression of papillomas induced by the initiation--promotion protocol in NMRI mouse skin.

scientific article published in January 1995

Maximum intensity breast diffusion MRI for BI-RADS 4 lesions detected on X-ray mammography.

scientific article

Methods and open-source toolkit for analyzing and visualizing challenge results

scientific article published in 2021

Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity

scientific article published on 19 July 2019

Modeling cancer detection: tumor size as a source of information on unobservable stages of carcinogenesis

scientific article published in June 2001

Modeling dose-response functions for combination treatments with log-logistic or Weibull functions

scientific article published on 30 November 2019

Modeling the number and size of hepatic focal lesions following exposure to 2,3,7,8-TCDD.

scientific article published in May 1996

Modelling the genesis and treatment of cancer: the potential role of physiologically based pharmacodynamics.

scientific article

Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism.

scientific article published in January 2000

Molecular approaches to the identification of biomarkers of exposure and effect--report of an expert meeting organized by COST Action B15. November 28, 2003.

scientific article

Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions-A calibration approach

Morphologic and functional scoring of cystic fibrosis lung disease using MRI

scholarly article by Monika Eichinger et al published June 2012 in European Journal of Radiology

Morphology, metabolism, microcirculation, and strength of skeletal muscles in cancer-related cachexia

scientific article published in January 2009

Multimodal hypoxia imaging and intensity modulated radiation therapy for unresectable non-small-cell lung cancer: the HIL trial

scientific article published on 14 September 2012

Multiple-rater kappas for binary data: Models and interpretation

scientific article

Multistage models of carcinogenesis: an approximation for the size and number distribution of late-stage clones

scientific article published in December 1994

Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors

article

Natural variants in the major neutralizing epitope of human papillomavirus minor capsid protein L2.

scientific article published on 3 October 2012

Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire

scientific article

Neural differentiation of embryonic stem cells is induced by signalling from non-neural niche cells

scientific article published in January 2006

Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival.

scientific article published on 02 March 2017

New in vitro system to predict chemotherapeutic efficacy of drug combinations in fresh tumor samples

scientific article published on 02 March 2017

Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures

article

Optimal experimental designs for dose-response studies with continuous endpoints

scientific article published on 26 August 2014

Optimization and prevalidation of the in vitro ERalpha CALUX method to test estrogenic and antiestrogenic activity of compounds

scientific article

Origins of the mutational origin of cancer

Parametric modeling and optimal experimental designs for estimating isobolograms for drug interactions in toxicology

scientific article published on 27 November 2017

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

scientific article published on 03 December 2018

Porphyrin studies in TCDD-exposed workers

scientific article published on 01 January 1994

Power gains by using external information in clinical trials are typically not possible when requiring strict type I error control

scientific article published on 02 July 2019

Prediction accuracy and variable selection for penalized cause-specific hazards models.

scientific article

Prediction of clinical response to drugs in ovarian cancer using the chemotherapy resistance test (CTR-test).

scientific article published on 27 October 2017

Prevalidation of a rat liver foci bioassay (RLFB) based on results from 1600 rats: a study report

scientific article published in January 2003

Proposal for a New Prognostic Score for Linac-Based Radiosurgery in Cerebral Arteriovenous Malformations

Protocol of the VICTORIA study: personalized vitamin D supplementation for reducing or preventing fatigue and enhancing quality of life of patients with colorectal tumor - randomized intervention trial

scientific article published on 08 August 2020

Quantitative Emphysema Distribution in Anatomic and Non-anatomic Lung Regions

Quantitative dynamic 18F-fluorodeoxyglucose positron emission tomography/computed tomography before autologous stem cell transplantation predicts survival in multiple myeloma

scientific article published on 14 February 2019

Quantitative in vitro to in vivo extrapolation of tissues toxicity

scientific article published on 9 February 2015

Randomized clinical trial: myths around elementary statistical principles

scientific article published in December 2003

Reduced Expression of Interleukin-2 Decreases the Frequency of Alopecia Areata Onset in C3H/HeJ Mice

article

Repeatability and reproducibility of quantitative whole-lung perfusion magnetic resonance imaging

scientific article published on August 2011

Report of the EPAA-ECVAM workshop on the validation of Integrated Testing Strategies (ITS).

scientific article published on July 2012

Respiratory displacement of the thoracic aorta: physiological phenomenon with potential implications for thoracic endovascular repair

scientific article published on 12 May 2009

Robust biclustering by sparse singular value decomposition incorporating stability selection

scientific article published on 02 June 2011

Selection of test methods to be included in a testing strategy to predict acute oral toxicity: an approach based on statistical analysis of data collected in phase 1 of the ACuteTox project

scientific article

Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation

scientific article

Semi-automated volumetric analysis of lymph node metastases in patients with malignant melanoma stage III/IV--a feasibility study

scientific article

Serological analysis of human renal cell carcinoma

scientific article published in May 2006

Simulation-based comparison of two approaches frequently used for dynamic contrast-enhanced MRI.

scientific article published in September 2009

Spontaneous lymphoblastoid cell lines from patients with Epstein-Barr virus infection show highly variable proliferation characteristics that correlate with the expression levels of viral microRNAs

scientific article published on 30 September 2019

Statistical models for low dose exposure

article

Statistical strategies for averaging EC50 from multiple dose-response experiments

scientific article published on 8 October 2014

Stochastic time-concentration activity models for cytotoxicity in 3D brain cell cultures

scientific article published on 14 March 2013

Summarizing EC50 estimates from multiple dose-response experiments: a comparison of a meta-analysis strategy to a mixed-effects model approach

scientific article published on 29 January 2014

Synergistic hepatocarcinogenic effect of hepadnaviral infection and dietary aflatoxin B1 in woodchucks.

scientific article

TTV infection in colorectal cancer tissues and normal mucosa

Targeted Therapy in Advanced Melanoma With Rare BRAF Mutations

scientific article published on 03 October 2019

The European water-based environmental quality standard for pentachlorophenol is NOT protective of benthic organisms

scientific article

The Exact Formula for Tumor Incidence in the Two-Stage Model

article

The Feasibility of Low Mechanical Index Contrast Enhanced Ultrasound (CEUS) in Distinguishing Malignant from Benign Thoracic Lesions

The application of a multistage model that incorporates DNA damage and repair to the analysis of initiation/promotion experiments

scientific article published on July 1991

The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers

scientific article published on 30 December 2016

The design heatmap: A simple visualization of D -optimality design problems

scientific article published on 14 October 2020

The impact of data transformations on concentration-response modeling

scientific article

The role of interim 18F-FDG PET/CT in prediction of response to ipilimumab treatment in metastatic melanoma.

scientific article published on 24 February 2018

The role of perfusion effects in monitoring of chemoradiotherapy of rectal carcinoma using diffusion-weighted imaging

scientific article published on 11 December 2013

The use of cell proliferation data in modeling of skin carcinogenesis.

scientific article

The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: results from the European Project ACuteTox

scientific article published on 16 August 2012

Threshold dose response for tumor induction by genotoxic carcinogens modeled via cell-cycle delay.

scientific article published in May 1999

Time- and Dose-Dependency of Radiographic Normal Tissue Changes of the Lung After Stereotactic Radiotherapy

Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters

scientific article published on 28 August 2009

Transcriptomic analysis of untreated and drug-treated differentiated HepaRG cells over a 2-week period

scientific article

Transcriptomic hepatotoxicity signature of chlorpromazine after short- and long-term exposure in primary human sandwich cultures

scientific article published on 2 August 2013

Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing

scientific article

Tubular Dickkopf-3 promotes the development of renal atrophy and fibrosis

scientific article published on 21 January 2016

Use of LDH and autoimmune side effects to predict response to ipilimumab treatment.

scientific article published on September 2016

Validation of Fourier decomposition MRI with dynamic contrast-enhanced MRI using visual and automated scoring of pulmonary perfusion in young cystic fibrosis patients

scientific article

Why rankings of biomedical image analysis competitions should be interpreted with care ⬇️

scientific article published in Nature Communications

Woodchuck hepatitis virus replication and antigen expression gradually decrease in preneoplastic hepatocellular lineages

scientific article published in October 2002

Xenomorphic hepatocellular precursors and neoplastic progression of tigroid cell foci induced in rats with low doses of N-nitrosomorpholine

scientific article published on 01 December 1998

[Gait analysis in limb-preserving tumour surgery--kinematic gait patterns after resection of malignant bone tumours near the knee joint]

scientific article published on 01 November 2007

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