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List of works by Aldo Galeone

1H NMR studies of the 5-(hydroxymethyl)-2'-deoxyuridine containing TF1 binding site

scientific article

1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine

scientific article published in May 2003

2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures.

scientific article published in September 2000

5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification

scientific article published on 11 September 2014

8-methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures

scientific article

A BUNCH-OLIGONUCLEOTIDE FORMING STABLE MONOMOLECULAR QUADRUPLEX CONTAINING A T-TETRAD

scientific article published on 01 January 2005

A Topological Classification of G-Quadruplex Structures

scientific article published on 01 January 2007

A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract

A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3′-3′ or 5′-5′ inversion of polarity site

A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site

scientific article published on 30 July 2013

A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures

scientific article

A straightforward modification in the thrombin binding aptamer improving the stability, affinity to thrombin and nuclease resistance

scientific article published on 08 October 2014

Affinity, stability and polarity of binding of the TATA binding protein governed by flexure at the TATA Box.

scientific article published in October 1998

Automated solid phase synthesis of cyclic oligonucleotides: a further improvement

scientific article published on 01 October 1995

Backbone modified TBA analogues endowed with antiproliferative activity

scientific article

Biophysical properties of quadruple helices of modified human telomeric DNA.

scientific article

Circular dichroism and thermal melting differentiation of Hoechst 33258 binding to the curved (A(4)T(4)) and straight (T(4)A(4)) DNA sequences

scientific article published in June 2002

Conformation of the circular dumbbell d<pCGC-TT-GCG-TT>: structure determination and molecular dynamics

scientific article published in December 1995

Design and NMR Study of an Immobile DNA Four‐Way Junction Containing 38 Nucleotides ⬇️

scientific article published on October 15, 1997

Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands

scientific article published on September 2011

Effect of a modified thymine on the structure and stability of [d(TGGGT)]4 quadruplex

scientific article

Effect of gamma-hydroxypropano deoxyguanosine, the major acrolein-derived adduct, on monomolecular quadruplex structure of telomeric repeat d(TTAGGG)(4).

scientific article published in November 2004

Effect of the Introduction of an A-Residue into A Quadruplex Forming Oligonucleotide Containing A 5′-5′ Polarity of Inversion Site

scientific article published on 01 January 2007

Effects of 8-methyl-2'-deoxyadenosine incorporation into quadruplex forming oligodeoxyribonucleotides

scientific article published in February 2005

Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes

scientific article published on 27 October 2010

Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures

scientific article

Effects of the introduction of inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT

scientific article published on 20 January 2009

Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue

scientific article published on 12 February 2014

Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions.

scientific article

G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine

Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence

scientific article published on 22 November 2018

INTERACTION OF DISTAMYCIN A AND NETROPSIN WITH QUADRUPLEX AND DUPLEX STRUCTURES: A COMPARATIVE1H-NMR STUDY

Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends

scientific article published on 27 July 2016

Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops.

scientific article published on 10 May 2018

Interrelations of secondary structure stability and DNA-binding affinity in the bacteriophage SPO1-encoded type II DNA-binding protein TF1.

scientific article published on February 1994

Investigating the properties of TBA variants with twin thrombin binding domains

scientific article published on 24 June 2019

Localized DNA flexibility contributes to target site selection by DNA-bending proteins.

scientific article

MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma

scientific article

MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines

scientific article published on 26 January 2013

MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma

scientific article (publication date: 2009)

Molecular Modelling Studies of Four Stranded Quadruplexes Containing A 3′-3′ or 5′-5′ Inversion of Polarity Site

scholarly article by Ada Virno et al published 26 November 2007 in Nucleosides, Nucleotides & Nucleic Acids

Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality

scientific article

More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures.

scientific article published on 28 November 2013

Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer

scientific article

Oligonucleotide delivery in cancer therapy

scientific article

On the connection between inherent DNA flexure and preferred binding of hydroxymethyluracil-containing DNA by the type II DNA-binding protein TF1.

scientific article

PNA-DNA Chimeras Forming Quadruplex Structures ⬇️

scientific article published on May 1, 2003

Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923

scientific article published on 06 August 2020

Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety

scientific article published on 11 May 2015

Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative

scientific article

Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity

scientific article

Slow conformational exchange in DNA minihairpin loops: a conformational study of the circular dumbbell d<pCGC-TT-GCG-TT>.

scientific article published in December 1995

Solid phase synthesis of 5-hydroxymethyluracil containing DNA

scientific article published in 1992

Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes

scientific article

Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4

scientific article

Structural investigations on the anti-HIV G-quadruplex-forming oligonucleotide TGGGAG and its analogues: evidence for the presence of an A-tetrad

scientific article published on 4 September 2012

Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin

scientific article published in 2014

Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine

scientific article published in March 2004

Synthesis and characterisation of poly(d,l-lactic acid)–idoxuridine conjugate

scientific article published on 01 March 1999

Synthesis and characterization of DNA quadruplexes containing T-tetrads formed by bunch-oligonucleotides

scientific article published on 01 February 2006

Synthesis and characterization of a bunchy oligonucleotide forming a monomolecular parallel quadruplex structure in solution

Synthesis and characterization of monomolecular DNA G-quadruplexes formed by tetra-end-linked oligonucleotides

scientific article published in July 2006

Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplexes

scientific article published in January 2007

Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine

scientific article

Synthesis of 3′−3′-Linked Pyrimidine Oligonucleotides Containing an Acridine Moiety for Alternate Strand Triple Helix Formation

Synthesis of 5-methylamino-2'-deoxyuridine derivatives

scientific article published in October 2001

Synthesis of quadruplex-forming tetra-end-linked oligonucleotides: effects of the linker size on quadruplex topology and stability

scientific article published in June 2009

Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide.

scientific article

Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity

article

The "Janus face" of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications.

scientific article published on 15 November 2017

The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives.

scientific article published on 09 September 2015

The abasic site lesions in the human telomeric sequence d[TA(G(3)T(2)A)(3)G(3)]: a thermodynamic point of view

scientific article published on 20 September 2012

The insertion of two 8-methyl-2'-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands

scientific article

The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures

scientific article

Thermodynamics of melting of the circular dumbbell d<pCGC-TT-GCG-TT>.

scientific article published in December 1995

Transferrin-conjugated SNALPs encapsulating 2'-O-methylated miR-34a for the treatment of multiple myeloma.

scientific article published on 13 February 2014

Twin hydroxymethyluracil-A base pair steps define the binding site for the DNA-binding protein TF1.

scientific article published in May 1997

Unprecedented right- and left-handed quadruplex structures formed by heterochiral oligodeoxyribonucleotides

scientific article published on 20 April 2011

Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites

scholarly article in Journal of Chemistry, 2015

Unusual monomolecular DNA quadruplex structures using bunch-oligonucleotides

scientific article published in January 2005

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