Search filters

List of works by Jean-Pierre Gorvel

"If you bring an alarm, we will destroy it," said Brucella to the host cell

scientific article published on May 2014

A dominant-negative mutant of the Rab5 GTPase enhances T cell signaling by interfering with TCR down-modulation in transgenic mice

scientific article published on 01 December 1997

A molecular, genetic and immunological approach to the functioning of colicin A, a pore-forming protein

scientific article published on 01 February 1986

A toxin-antitoxin module of Salmonella promotes virulence in mice

scientific article

A two-component regulatory system playing a critical role in plant pathogens and endosymbionts is present in Brucella abortus and controls cell invasion and virulence.

scientific article published in July 1998

Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking

scientific article published on October 2002

Activation of mouse T lymphocytes by a monoclonal antibody to a developmentally regulated surface aminopeptidase (THAM).

scientific article

Aminopeptidase N- and human blood group A-antigenicity along the digestive tract and associated glands in the rabbit

scientific article published on 01 January 1985

Aminopeptidases and proteolipids of intestinal brush border.

scientific article published on January 1983

An evolutionary strategy for a stealthy intracellular Brucella pathogen

scientific article published on March 2011

An immunologist's look at the Rho and Rab GTP-binding proteins.

scientific article

Analysis of kinesin accumulation on Salmonella-containing vacuoles.

scientific article

Annexin II is a major component of fusogenic endosomal vesicles

scientific article published on March 1993

Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region

scientific article published in June 2005

Bacteria spurned by self-absorbed cells

scientific article published on 01 January 2005

Bacterial infection and non-Hodgkin's lymphoma

scientific article published on 15 May 2020

Bacterial manipulation of innate immunity to promote infection.

scientific article published on February 2010

Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom--synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region

scientific article published in April 1998

Bactericidal and antiendotoxic properties of short cationic peptides derived from a snake venom Lys49 phospholipase A2.

scientific article

Bartonella and Brucella--weapons and strategies for stealth attack

scientific article published on August 2013

Biogenesis of Salmonella typhimurium-containing vacuoles in epithelial cells involves interactions with the early endocytic pathway

scientific article

Brucella CβG induces a dual pro- and anti-inflammatory response leading to a transient neutrophil recruitment

scientific article

Brucella T4SS: the VIP pass inside host cells

scientific article published on 11 January 2013

Brucella abortus Lipopolysaccharide in Murine Peritoneal Macrophages Acts as a Down-Regulator of T Cell Activation

article

Brucella abortus induces Irgm3 and Irga6 expression via type-I IFN by a MyD88-dependent pathway, without the requirement of TLR2, TLR4, TLR5 and TLR9.

scientific article published on 9 September 2009

Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern

scientific article

Brucella control of dendritic cell maturation is dependent on the TIR-containing protein Btp1.

scientific article

Brucella coopts the small GTPase Sar1 for intracellular replication

scientific article

Brucella discriminates between mouse dendritic cell subsets upon in vitro infection.

scientific article published on 25 November 2015

Brucella evasion of adaptive immunity

scientific article published on February 2013

Brucella lipopolysaccharide acts as a virulence factor.

scientific article published in February 2005

Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells

scientific article

Brucella: Reservoirs and Niches in Animals and Humans

scientific article published in 2021

Brucellosis vaccines: assessment of Brucella melitensis lipopolysaccharide rough mutants defective in core and O-polysaccharide synthesis and export

scientific article published on 23 July 2008

BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions

scientific article published on 08 July 2013

Cellular localization of class I (HLA-A, B, C) and class II (HLA-DR and DQ) MHC antigens on the epithelial cells of normal human jejunum

scientific article published on 01 January 1984

Cervical Lymph Nodes as a Selective Niche for Brucella during Oral Infections

scientific article published on January 2014

Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts

scientific article published on February 2006

Characterization of a Lysozyme-Major Histocompatibility Complex Class II Molecule-loading Compartment as a Specialized Recycling Endosome in Murine B Lymphocytes

scientific article published in Journal of Biological Chemistry

Characterization of a peptide-loading compartment by monoclonal antibodies.

scientific article

Characterization of intestinal membrane vesicles with flow cytometry

scientific article published on 01 January 1988

Characterization of the neutral aminopeptidase activity associated to the mouse thymocyte-activating molecule

scientific article published in April 1990

Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer

scientific article published on 03 January 2017

Confocal microscopy as a tool to reveal the tridimensional organization of intracellular lumens and intercellular cysts in a human colon adenocarcinoma cell line

scientific article published on January 1990

Conformational change of rabbit aminopeptidase N into enterocyte plasma membrane domains analyzed by flow cytometry fluorescence energy transfer.

scientific article

Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection

Contribution of bacterial effectors and host proteins to the composition and function of Salmonella-induced tubules

scientific article published on 26 September 2018

Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing

scientific article published on October 2002

Cyclic β-1,2-glucan is a brucella virulence factor required for intracellular survival

scientific article published on 08 May 2005

Cyclic β-Glucans at the bacteria-host cells interphase: one sugar ring to rule them all.

scientific article published on 6 April 2018

Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs.

scientific article published on February 1996

Different endocytic compartments are involved in the tight association of class II molecules with processed hen egg lysozyme and ribonuclease A in B cells

scientific article published on 01 June 1995

Differential inductions of TNF-alpha and IGTP, IIGP by structurally diverse classic and non-classic lipopolysaccharides

scientific article published on March 2006

Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity

scientific article

Distribution, location, and transcriptional profile of Peyer’s patch conventional DC subsets at steady state and under TLR7 ligand stimulation

scientific article published on 05 April 2017

Early endosome membrane dynamics characterized by flow cytometry.

scientific article published on September 1997

Effector proteins support the asymmetric apportioning of Salmonella during cytokinesis.

scientific article

Enzymatic and immunological properties of the protease form of aminopeptidases N and A from pig and rabbit intestinal brush border

scientific article published on 01 March 1981

Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia

scientific article

Essential role of the VirB machinery in the maturation of the Brucella abortus-containing vacuole

scientific article published on 01 March 2001

Evidence for selective transport of two brush-border glycoproteins from endoplasmic reticulum to Golgi complex in rabbit enterocytes

article

Evidence for the transit of aminopeptidase N through the basolateral membrane before it reaches the brush border of enterocytes

article

Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV).

scientific article published on July 1991

Expression of a subclass of human blood group A antigenicity in A+ rabbit jejunum: specific glycosylation of the glycocalyx and a 140 K brush border glycoprotein

scientific article published on 01 January 1987

Expression of sucrase-isomaltase and dipeptidylpeptidase IV in human small intestine and colon.

scientific article

Expression of the human A, B and related antigens in the jejunum of human and rabbit small intestines in particular on the brush border membrane glycoproteins

scientific article published on 01 December 1987

Flow cytometric sorting and biochemical characterization of the late endosomal rab7-containing compartment.

scientific article

Flow cytometry is a new method for the characterization of intestinal plasma membrane

scientific article published on July 1984

Flow cytometry, a very useful technique for the characterization of intestinal membrane vesicles

scientific article published on 01 January 1986

Further characterization of an early expressed glycoprotein of the rabbit small intestinal brush border. Its interaction with some hydrolases

scientific article published on 01 September 1986

GTPases of the Rho subfamily are required for Brucella abortus internalization in nonprofessional phagocytes: direct activation of Cdc42.

scientific article published on 28 September 2001

Gene expression profiling of the Peyer's patch mononuclear phagocyte system

scientific article

Glycyl-L-proline transport in rabbit enterocyte basolateral-membrane vesicles

scientific article published on August 1990

HLA-DR4 and HLA-DR10 motifs that carry susceptibility to rheumatoid arthritis bind 70-kD heat shock proteins.

scientific article

Helicobacter pylori impairs murine dendritic cell responses to infection

scientific article

Human blood group A-like determinants as marker of the intracellular pools of glycoproteins in secretory and absorbing of A+ rabbit jejunum

scientific article published on 01 January 1984

Human plasma cells express granzyme B.

scientific article

Identification and structural characterization of an unusual mycobacterial monomeromycolyl-diacylglycerol

scientific article published in August 2005

Identification of Brucella spp. genes involved in intracellular trafficking.

scientific article

Identification of Salmonella functions critical for bacterial cell division within eukaryotic cells

scientific article

Identification of a Brucella spp. secreted effector specifically interacting with human small GTPase Rab2.

scientific article published on 30 May 2011

Identification of an early expressed marker of the luminal membrane of rabbit small intestinal columnar cells. Presence of a homologous antigen in kidney proximal tubules and glomeruli

scientific article published on 01 January 1986

Identification of glycoproteins bearing human blood group A determinants in rabbit enterocyte plasma membranes

scientific article published on 01 June 1982

Identification of lptA, lpxE, and lpxO, Three Genes Involved in the Remodeling of Brucella Cell Envelope.

scientific article published in January 2017

Identification of two putative rickettsial adhesins by proteomic analysis

scientific article published on 28 February 2006

Immunomodulatory properties of Brucella melitensis lipopolysaccharide determinants on mouse dendritic cells in vitro and in vivo.

scientific article

Improved methods for producing outer membrane vesicles in Gram-negative bacteria.

scientific article published in July 2004

In search of Brucella abortus type IV secretion substrates: screening and identification of four proteins translocated into host cells through VirB system

scientific article

In vivo identification and characterization of CD4⁺ cytotoxic T cells induced by virulent Brucella abortus infection.

scientific article

Inactivation of formyltransferase (wbkC) gene generates a Brucella abortus rough strain that is attenuated in macrophages and in mice

scientific article published on 19 June 2010

Infection by Brucella melitensis or Brucella papionis modifies essential physiological functions of human trophoblasts

scientific article published on 14 March 2019

Innate and adaptive immune functions of peyer's patch monocyte-derived cells

scientific article

Interaction between the SifA Virulence Factor and Its Host Target SKIP Is Essential for Salmonella Pathogenesis

scientific article

Interactions of rab5 with cytosolic proteins ⬇️

scientific article published in Journal of Biological Chemistry

Internal affairs: investigating the Brucella intracellular lifestyle

scientific article published on 22 March 2012

Intestinal phosphate transport: localization, properties and identification, a progress report

scientific article published on 01 January 1988

Intracellular bacteria interfere with dendritic cell functions: role of the type I interferon pathway

scientific article

Intracellular trafficking of Parachlamydia acanthamoebae

scientific article published on April 2005

Intracellular trafficking study of a RB51 B. abortus vaccinal strain isolated from cow milk

scientific article published in March 2004

Intracellular transport of molecules engaged in the presentation of exogenous antigens.

scientific article published on January 1998

Invariant chain induces a delayed transport from early to late endosomes

scientific article published on February 1995

Is Brucella an enteric pathogen?

scientific article published on 27 January 2009

Link between impaired maturation of phagosomes and defective Coxiella burnetii killing in patients with chronic Q fever

scientific article published on 7 October 2004

Lipopolysaccharide as a target for brucellosis vaccine design.

scientific article published on 05 December 2012

Lipopolysaccharides with acylation defects potentiate TLR4 signaling and shape T cell responses

scientific article

Localization by immunofluorescence and histochemical labeling of aminopeptidase N in relation to its biosynthesis in rabbit and pig enterocytes

scientific article published on 01 February 1982

Lysosomal accumulation and recycling of lipopolysaccharide to the cell surface of murine macrophages, an in vitro and in vivo study

scientific article published on 01 June 1999

Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells

scientific article published on August 2004

Maturation steps of the Salmonella-containing vacuole.

scientific article

Microbiology. Bacterial bushwacking through a microtubule jungle

scientific article published on November 2006

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

scientific article

Mimivirus giant particles incorporate a large fraction of anonymous and unique gene products

scientific article

Modulation of endocytosis in nuclear factor IL-6(-/-) macrophages is responsible for a high susceptibility to intracellular bacterial infection

scientific article published on 01 March 1999

Molecular motors hijacking by intracellular pathogens.

scientific article

Molecular organization of the intestinal brush border

scientific article published on September 1988

Nanobacteria are mineralo fetuin complexes

scientific article published on 8 February 2008

Neutrophils exert a suppressive effect on Th1 responses to intracellular pathogen Brucella abortus

scientific article

Omp25-dependent engagement of SLAMF1 by Brucella abortus in dendritic cells limits acute inflammation and favours bacterial persistence in vivo

scientific article published on 01 April 2020

Pathogen-endoplasmic-reticulum interactions: in through the out door

scientific article

Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme

scientific article published in October 2009

Pathogenic brucellae replicate in human trophoblasts.

scientific article published on 9 January 2013

Persistence of in the Bone Marrow of Infected Mice

scientific article published on 03 December 2018

Peyer's patch dendritic cells sample antigens by extending dendrites through M cell-specific transcellular pores

scientific article

Phosphate transport in intestinal brush-border membrane

scientific article published on 01 April 1988

Proteome analysis of Rickettsia conorii by two-dimensional gel electrophoresis coupled with mass spectrometry

scientific article

Proteome analysis of Rickettsia felis highlights the expression profile of intracellular bacteria

scientific article

Purification and characterization of the rabbit intestinal brush-border aminopeptidase A

scientific article published on 01 September 1980

RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4.

scientific article

Recognition of sodium- and potassium-dependent adenosine triphosphatase in organs of the mouse by means of a monoclonal antibody

scientific article published in January 1983

Recognition of sodium- and potassium-dependent adenosine triphosphatase on mouse lymphoid cells by means of a monoclonal antibody

scientific article published in January 1984

Recruitment of Activated p56lckon Endosomes of CD2-triggered T Cells, Colocalization with ZAP-70

scientific article published in Journal of Biological Chemistry

Regulation of kinesin-1 activity by the Salmonella enterica effectors PipB2 and SifA

scientific article published on 14 May 2020

Remodelling of the actin cytoskeleton is essential for replication of intravacuolar Salmonella

scientific article published in August 2001

Renewal of goblet cell mucus granules during the cell migration along the crypt-villus axis in rabbit jejunum: an immunolabeling study

scientific article published on 01 January 1989

Rickettsia conorii and R. prowazekii proteome analysis by 2DE-MS: a step toward functional analysis of rickettsial genomes

scientific article published in December 2005

Rough mutants defective in core and O-polysaccharide synthesis and export induce antibodies reacting in an indirect ELISA with smooth lipopolysaccharide and are less effective than Rev 1 vaccine against Brucella melitensis infection of sheep.

scientific article published on 30 January 2009

SKIP, the host target of the Salmonella virulence factor SifA, promotes kinesin-1-dependent vacuolar membrane exchanges

scientific article published on 6 April 2010

Salmonella detoxifying enzymes are sufficient to cope with the host oxidative burst

scientific article published on 21 March 2011

Salmonella typhimurium SifA effector protein requires its membrane-anchoring C-terminal hexapeptide for its biological function

scientific article published on 5 February 2003

Small GTPases and Brucella entry into the endoplasmic reticulum ⬇️

scientific article published on December 1, 2012

Some news from the unknown soldier, the Peyer's patch macrophage.

scientific article published on 31 January 2018

Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence.

scientific article published on 11 February 2016

Subcellular fractionation and subcellular localization of aminopeptidase N in the rabbit enterocytes

scientific article published on 01 January 1986

Subcellular localization of class I (A,B,C) and class II (DR and DQ) MHC antigens in jejunal epithelium of children with coeliac disease

scientific article published on 01 January 1987

Subversion of mouse dendritic cell subset function by bacterial pathogens

scientific article published on 07 October 2015

Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification

scientific article published on March 2002

Synthesis of phosphatidylcholine, a typical eukaryotic phospholipid, is necessary for full virulence of the intracellular bacterial parasite Brucella abortus

scientific article published on 01 August 2006

The Brucella abortus phosphoglycerate kinase mutant is highly attenuated and induces protection superior to that of vaccine strain 19 in immunocompromised and immunocompetent mice

scientific article

The N-terminal domain of a rab protein is involved in membrane-membrane recognition and/or fusion.

scientific article

The O-chain of Brucella abortus lipopolysaccharide induces SDS-resistant MHC class II molecules in mouse B cells.

scientific article published in September 1994

The Peyer's Patch Mononuclear Phagocyte System at Steady State and during Infection

scientific article published on 2 October 2017

The Salmonella effector protein SifA plays a dual role in virulence.

scientific article

The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming

scientific article

The glyceraldehyde-3-phosphate dehydrogenase and the small GTPase Rab 2 are crucial for Brucella replication

scientific article published on 26 June 2009

The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition

scientific article

The mouse T-lymphocyte-activating molecule THAM is associated to ECTO-aminopeptidase activity

scientific article

The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells

scientific article

The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche.

scientific article published on 2 October 2006

The two-component system BvrR/BvrS essential for Brucella abortus virulence regulates the expression of outer membrane proteins with counterparts in members of the Rhizobiaceae

scientific article

The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles

scientific article published on 15 July 2010

Transcriptome analysis of the Brucella abortus BvrR/BvrS two-component regulatory system

scientific article

Two-dimensional gel electrophoresis analysis of endovacuolar organelles

scientific article

Tyrosine and serine protein kinase activities associated with ligand-induced internalized TCR/CD3 complexes

scientific article published on April 1997

Tyr→Trp-substituted peptide 115-129 of a Lys49 phospholipase A2 expresses enhanced membrane-damaging activities and reproduces its in vivo myotoxic effect

scientific article published on 01 November 1999

Unusual intracellular trafficking of Salmonella typhimurium in human melanoma cells

scientific article published in June 2001

Vaccine development targeting lipopolysaccharide structure modification

scientific article

Virulence factors in brucellosis: implications for aetiopathogenesis and treatment.

scientific article published on 19 December 2007

Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening

scientific article

Virulent Brucella abortus Prevents Lysosome Fusion and Is Distributed within Autophagosome-Like Compartments ⬇️

scientific article published on May 1, 1998

When intracellular pathogens invade the frontiers of cell biology and immunology

scientific article published on October 1997

[Cell polarity and protein transport in digestive epithelial cells]

scientific article published on 01 October 1991

Paulina is supported by:

About Paulina

Help