List of works by Karl A Scheidt

A Biocatalytic Route to Highly Enantioenriched β-Hydroxydioxinones

scientific article published on 2 March 2017

A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products

scientific article published on 20 June 2017

A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK Kinase Family

scientific article

A Concise Enantioselective Synthesis and Cytotoxic Evaluation of the Anticancer Rotenoid Deguelin Enabled by a Tandem Knoevenagel/Conjugate Addition/Decarboxylation Sequence

scientific article published on August 2013

A Concise, Enantioselective Approach for the Synthesis of Yohimbine Alkaloids

scientific article published on 17 January 2020

A Cooperative Hydrogen Bond Donor/Brønsted Acid System for the Enantioselective Synthesis of Tetrahydropyrans

scientific article published on 27 November 2018

A Cooperative N-Heterocyclic Carbene/Palladium Catalysis System.

scientific article

A Cooperative Ternary Catalysis System for Asymmetric Lactonizations of α-Ketoesters

scientific article published on 14 August 2017

A biomimetic strategy to access the silybins: total synthesis of (-)-isosilybin A.

scientific article published on 17 December 2014

A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones

scientific article

A continuum of progress: applications of N-hetereocyclic carbene catalysis in total synthesis

scientific article published on 16 October 2012

A cooperative N-heterocyclic carbene/chiral phosphate catalysis system for allenolate annulations

scientific article published on 4 June 2014

A dual Lewis base activation strategy for enantioselective carbene-catalyzed annulations.

scientific article published on 11 July 2013

A facile synthesis of UiO-66, UiO-67 and their derivatives

scientific article published on 01 October 2013

A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4

scientific article published in 2013

A frequency domain existence proof of single-molecule surface-enhanced Raman spectroscopy

scientific article published on 01 December 2007

A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles

scientific article published on 06 November 2006

A highly enantioselective intramolecular Michael reaction catalyzed by N-heterocyclic carbenes

scientific article published on January 2007

A mixed dicarboxylate strut approach to enhancing catalytic activity of a de novo urea derivative of metal-organic framework UiO-67.

scientific article published in December 2013

A tandem isomerization/prins strategy: iridium(III)/Brønsted acid cooperative catalysis

scientific article published on 11 November 2013

Amide bonds made in reverse

scientific article published in Nature

Amide enolate additions to acylsilanes: in situ generation of unusual and stereoselective homoenolate equivalents

scientific article published on 01 July 2009

An Enantioselective Cross-Dehydrogenative Coupling Catalysis Approach to Substituted Tetrahydropyrans

scientific article published on 10 May 2018

An N-heterocyclic carbene/Lewis acid strategy for the stereoselective synthesis of spirooxindole lactones.

scientific article published on 4 April 2012

An NMR method for assigning relative stereochemistry to beta-hydroxy ketones deriving from aldol reactions of methyl ketones

scientific article published on 01 June 2002

An unusual dianion equivalent from acylsilanes for the synthesis of substituted beta-keto esters

scientific article published on 10 March 2008

Anion chelation by amido acid functionalized fused quartz/water interfaces studied by nonlinear optics

scientific article published on 11 May 2007

Assembly of four diverse heterocyclic libraries enabled by Prins cyclization, Au-catalyzed enyne cycloisomerization, and automated amide synthesis.

scientific article

Asymmetric homoenolate additions to acyl phosphonates through rational design of a tailored N-heterocyclic carbene catalyst.

scientific article

Azaindole synthesis through dual activation catalysis with N-heterocyclic carbenes

scientific article published on July 2016

Calcium(ii)-catalyzed enantioselective conjugate additions of amines.

scientific article published on 10 January 2018

Carbene-Catalyzed Enantioselective Decarboxylative Annulations to Access Dihydrobenzoxazinones and Quinolones

scientific article published on 27 March 2019

Catalytic Kinetic Resolution of a Dynamic Racemate: Highly Stereoselective β-Lactone Formation by N-Heterocyclic Carbene Catalysis

scientific article

Catalytic additions of acylsilanes to imines: an acyl anion strategy for the direct synthesis of alpha-amino ketones

scientific article published on 01 November 2004

Catalytic asymmetric alkylation of substituted isoflavanones

scientific article published on September 2009

Catalytic conjugate additions of carbonyl anions under neutral aqueous conditions

scientific article published in October 2005

Catalytic dynamic kinetic resolutions with N-heterocyclic carbenes: asymmetric synthesis of highly substituted β-lactones

scientific article published on 14 June 2012

Catalytic enantioselective alpha-acylvinyl anion reactions of silyloxyallenes

scientific article published on January 2007

Catalytic enantioselective synthesis of 2-aryl-chromenes

scientific article published on June 2014

Catalytic enantioselective synthesis of flavanones and chromanones

scientific article published on 10 March 2007

Catalytic enantioselective total syntheses of bakkenolides I, J, and S: application of a carbene-catalyzed desymmetrization

scientific article published on June 2010

Catalytic multicomponent reactions for the synthesis of N-aryl trisubstituted pyrroles

scientific article published on 27 January 2007

Catalytic multicomponent synthesis of highly substituted pyrroles utilizing a one-pot sila-Stetter/Paal-Knorr strategy

scientific article published on 01 July 2004

Catalytic, Enantioselective β-Protonation through a Cooperative Activation Strategy

scientific article published on 25 April 2017

Catalytic, three-component assembly reaction for the synthesis of pyrrolidines

scientific article published on 01 September 2003

Combined Photoredox and Carbene Catalysis for the Synthesis of Ketones from Carboxylic Acids

scientific article published on 02 March 2020

Combined Photoredox/Enzymatic C-H Benzylic Hydroxylations

scientific article published on 26 September 2019

Computational planning of the synthesis of complex natural products

scientific article published on 13 October 2020

Concise syntheses of the abyssinones and discovery of new inhibitors of prostate cancer and MMP-2 expression

scientific article published on November 2010

Conversion of alpha,beta-unsaturated aldehydes into saturated esters: an Umpolung reaction catalyzed by nucleophilic carbenes

scientific article published on 01 March 2005

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

scientific article

Cooperative Lewis acid/N-heterocyclic carbene catalysis

scientific article

Cooperative N-heterocyclic carbene/Lewis acid catalysis for highly stereoselective annulation reactions with homoenolates

scientific article published on April 2010

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to gamma-lactams

scientific article published on 18 July 2010

Copper(I)-catalyzed disilylation of alkylidene malonates employing a Lewis base activation strategy

scientific article published on 01 January 2004

Copper-promoted N-arylations of cyclic imides within six-membered rings: a facile route to arylene-based organic materials

scientific article published in February 2005

Correction to "Enantioselective Synthesis of α-Amidoboronates Catalyzed by Planar-Chiral NHC-Cu(I) Complexes"

scientific article published on 09 October 2018

Correction: A Fluorescence-Based Thermal Shift Assay Identifies Inhibitors of Mitogen Activated Protein Kinase Kinase 4.

scientific article published on 23 December 2013

Direct amination of homoenolates catalyzed by N-heterocyclic carbenes

scientific article published on 9 February 2008

Direct nucleophilic acylation of nitroalkenes promoted by a fluoride anion/thiourea combination

scientific article published on 01 April 2006

Discovering New Reactions with N-Heterocyclic Carbene Catalysis.

scientific article

Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression

scientific article

Efficient synthesis of acylsilanes using morpholine amides

scientific article published on 01 October 2004

Emerging Roles of in Situ Generated Quinone Methides in Metal-Free Catalysis

scientific article published on 11 August 2016

Enantioselective Friedel-Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes

scientific article published on 21 July 2007

Enantioselective MSPV Reduction of Ketimines Using 2-Propanol and (BINOL)AlIII

scientific article published on 01 March 2006

Enantioselective N-heterocyclic carbene catalyzed annulation reactions with imidazolidinones

scientific article published on 18 November 2013

Enantioselective Syntheses of Heteroyohimbine Natural Products: A Unified Approach through Cooperative Catalysis

scientific article published on 27 April 2015

Enantioselective Synthesis of α-Amidoboronates Catalyzed by Planar-Chiral NHC-Cu(I) Complexes

scientific article published on 16 August 2018

Enantioselective and diastereoselective Mukaiyama-Michael reactions catalyzed by bis(oxazoline) copper(II) complexes

scientific article published in May 2001

Enantioselective annulations for dihydroquinolones by in situ generation of azolium enolates

scientific article published on 15 July 2014

Enantioselective indole Friedel--Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes

scientific article published in September 2003

Enantioselective synthesis of (-)-exiguolide by iterative stereoselective dioxinone-directed Prins cyclizations

scientific article published on September 2011

Enantioselective synthesis of alpha,alpha-disubstituted cyclopentenes by an N-heterocyclic carbene-catalyzed desymmetrization of 1,3-diketones

scientific article published on 31 July 2007

Enantioselective synthesis of substituted indanones from silyloxyallenes

scientific article published in February 2010

Enantioselective β-Protonation by a Cooperative Catalysis Strategy

scientific article published on 4 May 2015

Ferrocene-based planar chiral imidazopyridinium salts for catalysis

scientific article published on 23 January 2015

Formation of Aza-ortho-quinone Methides Under Room Temperature Conditions: Cs2CO3 Effect

scientific article published on 26 June 2017

Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application

scientific article published on February 2015

Heterogeneous ozone oxidation reactions of 1-pentene, cyclopentene, cyclohexene, and a menthenol derivative studied by sum frequency generation

scientific article

High-throughput photocapture approach for reaction discovery

scientific article published on 01 June 2020

Highly diastereo- and enantioselective additions of homoenolates to nitrones catalyzed by N-heterocyclic carbenes

scientific article published on 31 January 2008

Highly selective alpha-acylvinyl anion additions to imines

scientific article published on 30 October 2008

Highly stereoselective Brønsted acid catalyzed synthesis of spirooxindole pyrans.

scientific article

Highly stereoselective formal [3 + 3] cycloaddition of enals and azomethine imines catalyzed by N-heterocyclic carbenes

scientific article published on 4 April 2007

Highly stereoselective synthesis of substituted gamma-lactams from acylsilanes

scientific article published on 01 January 2008

Hydroacylation of activated ketones catalyzed by N-heterocyclic carbenes

scientific article published on 01 April 2006

Impact of solvent polarity on N-heterocyclic carbene-catalyzed beta-protonations of homoenolate equivalents

scientific article published on September 2009

Intermolecular Cross-Acyloin Reactions by Fluoride-Promoted Additions of O-Silyl Thiazolium Carbinols.

scientific article

Intermolecular Reductive Couplings of Arylidene Malonates via Lewis Acid/Photoredox Cooperative Catalysis

scientific article published on 22 October 2018

Jammed Acid−Base Reactions at Interfaces

scientific article published on 19 November 2008

Lewis acid activated synthesis of highly substituted cyclopentanes by the N-heterocyclic carbene catalyzed addition of homoenolate equivalents to unsaturated ketoesters

scientific article published on 14 January 2011

Lewis acid-catalyzed conjugate additions of silyloxyallenes: a selective solution to the intermolecular Rauhut-Currier problem

scientific article published on 14 May 2008

Lewis base-catalyzed additions of alkynes using trialkoxysilylalkynes

scientific article published on 01 July 2005

MEK4 function, genistein treatment, and invasion of human prostate cancer cells

scientific article published on 28 July 2009

Metal-organic framework materials as catalysts

scientific article published on 17 March 2009

Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential Charges

scientific article published on 14 October 2019

N-Heterocyclic Carbene-Catalyzed Oxidations

scientific article published on April 2009

N-Heterocyclic Carbene-Promoted Rauhut]Currier Reactions between Vinyl Sulfones and α,β-Unsaturated Aldehydes

scientific article published on August 2011

N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins

scientific article

N-heterocyclic carbene-catalyzed conjugate additions of alcohols

scientific article published on September 2010

N-heterocyclic carbene-catalyzed enantioselective Mannich reactions with alpha-aryloxyacetaldehydes

scientific article published on December 2009

N-heterocyclic carbene-catalyzed oxidation of unactivated aldehydes to esters

scientific article published on 30 August 2008

N-heterocyclic carbene-catalyzed rearrangements of vinyl sulfones

scientific article published on 10 June 2011

N-heterocyclic carbene-initiated alpha-acylvinyl anion reactivity: additions of alpha-hydroxypropargylsilanes to aldehydes

scientific article

N-heterocyclic-carbene-catalyzed synthesis of 2-aryl indoles

scientific article published on 14 July 2014

NHC-Catalyzed Formal [2+2] Annulations of Allenoates for the Synthesis of Substituted Oxetanes

scientific article published on 14 November 2018

NHC-catalyzed reactions of aryloxyacetaldehydes: a domino elimination/conjugate addition/acylation process for the synthesis of substituted coumarins

scientific article published on January 2009

NHC-catalyzed/titanium(IV)-mediated highly diastereo- and enantioselective dimerization of enals

scientific article published on 27 January 2011

Non-'classical' MEKs: A review of MEK3-7 inhibitors

scientific article published on 23 April 2020

Nucleophilic acylation of o-quinone methides: an umpolung strategy for the synthesis of alpha-aryl ketones and benzofurans

scientific article published on 23 March 2007

Precision therapeutic targeting of human cancer cell motility.

scientific article

Prins-type macrocyclizations as an efficient ring-closing strategy in natural product synthesis

scientific article

Protonation of Homoenolate Equivalents Generated by N-Heterocyclic Carbenes

scientific article published on April 2008

Pyranone natural products as inspirations for catalytic reaction discovery and development

scientific article published on 6 March 2015

Reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis

scientific article published on 06 February 2019

Remarkably stable tetrahedral intermediates: carbinols from nucleophilic additions to N-acylpyrroles

scientific article

Single-flask synthesis of N-acylated indoles by catalytic dehydrogenative coupling with primary alcohols

scientific article published on April 2009

Single-molecule surface-enhanced Raman spectroscopy of crystal violet isotopologues: theory and experiment

scientific article published on 24 February 2011

Stereoselective Lewis acid-catalyzed alpha-acylvinyl additions

scientific article published on 01 December 2006

Stereoselective synthesis of alpha-silylamines by the direct addition of silyl anions to activated imines

scientific article published on 01 March 2005

Stereoselective synthesis of tetrahydropyran-4-ones from dioxinones catalyzed by scandium(III) triflate

scientific article published on 01 March 2005

Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors

scientific article

Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment.

scientific article published on 29 December 2007

Studies on the synthesis of bafilomycin A(1): stereochemical aspects of the fragment assembly aldol reaction for construction of the C(13)-C25) segment

scientific article

Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

scientific article published on 19 February 2019

Synthesis and Evaluation of Azolium-Based Halogen-Bond Donors

scientific article published on 08 July 2019

Synthesis and gas sorption properties of a metal-azolium framework (MAF) material

scientific article published in November 2009

Synthesis of (-)-epibatidine.

scientific article

Synthesis of (-)-okilactomycin by a Prins-type fragment-assembly strategy

scientific article

Synthesis of Enantioenriched α,α-Disubstituted Cyclopentenes Catalyzed by N-Heterocyclic Carbenes

scientific article published on January 2009

Synthesis of tertiary beta-hydroxy amides by enolate additions to acylsilanes

scientific article published on 01 December 2006

Tandem oxidation of allylic and benzylic alcohols to esters catalyzed by N-heterocyclic carbenes

scientific article published on 01 January 2007

Targeted Covalent Inhibition of Telomerase

scientific article published on 24 February 2020

The thiazolium-catalyzed Sila-Stetter reaction: conjugate addition of acylsilanes to unsaturated esters and ketones

scientific article published in March 2004

Thiazolium-catalyzed additions of acylsilanes: a general strategy for acyl anion addition reactions

scientific article published on 01 July 2006

Total Synthesis of (-)-Bafilomycin A1 : Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions

scientific article published on 01 June 1999

Total synthesis and structural revision of the marine macrolide neopeltolide

scientific article published in January 2008

Total synthesis and structure-activity investigation of the marine natural product neopeltolide

scientific article

Total synthesis of (-)-bafilomycin A(1).

scientific article

Urea metal-organic frameworks as effective and size-selective hydrogen-bond catalysts

scientific article published on 8 February 2012

Virtual High-Throughput Screening To Identify Novel Activin Antagonists

scientific article