List of works - Lavinia Paternoster

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis

scientific article

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

scientific article

A genome-wide association study of body mass index across early life and childhood

scientific article published on April 2015

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target

Adult height variants affect birth length and growth rate in children

scientific article

Age-of-onset information helps identify 76 genetic variants associated with allergic disease

scientific article published on 30 June 2020

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

scientific article published in Nature Communications

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study ⬇️

scientific article published on 23 February 2017

Association between CST3 rs2424577 Polymorphism and Corpulence Related Phenotypes during Lifetime in Populations of European Ancestry

scientific article published on 15 April 2011

Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity

scientific article

Association between apolipoprotein E genotype and carotid intima-media thickness may suggest a specific effect on large artery atherothrombotic stroke

scientific article published on 06 December 2007

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

scientific article

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

scientific article

Body stature growth trajectories during childhood and the development of myopia

scientific article

Cohort Profile: Nausea and vomiting during pregnancy genetics consortium (NVP Genetics Consortium).

scientific article published on 26 February 2016

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications

article

Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study

scientific article published on 11 November 2015

Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5.

scientific article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on November 2016

Describing the application of statistical shape modelling to DXA images to quantify the shape of the proximal femur at ages 14 and 18 years in the Avon Longitudinal Study of Parents and Children

scientific article published on 27 August 2019

Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.

scientific article

Eleven loci with new reproducible genetic associations with allergic disease risk

scientific article published on 18 April 2018

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

article

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

scientific article

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

scientific article published on 31 January 2019

Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study

scientific article published on 15 February 2018

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

scientific article

Genetic Epidemiology And Mendelian Randomization For Informing Disease Therapeutics: Conceptual And Methodological Challenges

scholarly article published 8 May 2017

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

scientific article published on March 2016

Genetic associations with brain microbleeds: Systematic review and meta-analyses.

scientific article published on 29 June 2011

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

scientific article

Genetic determinants of white matter hyperintensities on brain scans: a systematic assessment of 19 candidate gene polymorphisms in 46 studies in 19,000 subjects.

scientific article published on 30 April 2009

Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects

scientific article published on 11 December 2009

Genetic epidemiology and Mendelian randomization for informing disease therapeutics: Conceptual and methodological challenges

scientific article published on 5 October 2017

Genetic evidence of assortative mating in humans

article

Genetic influences on trajectories of systolic blood pressure across childhood and adolescence

scientific article published on 7 November 2013

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

scientific article published on 18 May 2011

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight

scientific article

Genetics of depressive symptoms in adolescence

scientific article published on 31 August 2017

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

scientific article published on 05 March 2019

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

scientific article published on February 2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

scholarly article by Johannes Waage et al published August 2018 in Nature Genetics

Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone

scientific article

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genome-wide association study identifies 48 common genetic variants associated with handedness

scientific article published on 28 September 2020

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study identifies four loci associated with eruption of permanent teeth

scientific article

Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes

scientific article published in September 2018

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

article

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

scientific article published on 3 January 2018

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances

scientific article published on 23 May 2013

Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position

scientific article

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

scientific article published on 06 February 2013

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide population-based association study of extremely overweight young adults--the GOYA study

scientific article (publication date: 2011)

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

scientific article

Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohorts

scientific article

Identification of novel loci associated with hip shape: a meta-analysis of genome-wide association studies

Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

scientific article published on 26 December 2019

Investigating causality in the association between vitamin D status and self-reported tiredness

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

Investigating the causal relationship between allergic disease and mental health

scientific article published in 2021

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

scientific article published on 7 October 2014

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.

scientific article

Maternal and fetal genetic contribution to gestational weight gain

article

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Mendelian Randomization in Case Only Studies: A Promising Approach to be Applied With Caution

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

scientific article

Mining the human phenome using allelic scores that index biological intermediates

scientific article

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

scientific article published on 19 October 2015

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

Non-syndromic Cleft Lip and Palate Polymorphisms Affect Normal Lip Morphology

scholarly article by Caryl Wilson-Nagrani et al published 2018 in Frontiers in Genetics

OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.

scientific article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Perinatal depression and omega-3 fatty acids: a Mendelian randomisation study

scientific article published on 9 May 2014

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

scientific article published on 16 November 2021

Robustness of the linear mixed effects model to error distribution assumptions and the consequences for genome-wide association studies

scientific article published in October 2014

Sex differences in proximal femur shape: findings from a population-based study in adolescents

scientific article published on 12 March 2020

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

scientific article published on 30 October 2017

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers

scientific article published on 4 December 2014

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Using SITAR (SuperImposition by Translation and Rotation) to estimate age at peak height velocity in Avon Longitudinal Study of Parents and Children

article

Using statistical shape modelling of DXA images to quantify the shape of the proximal femur at ages 14 and 18 years in the Avon Longitudinal Study of Parents and Children

Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.

scientific article

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

scientific article published in July 2012

What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review

scientific article published on 03 December 2019

When Will Mendelian Randomization Become Relevant for Clinical Practice and Public Health?

scientific article published in The Journal of the American Medical Association

List of works by Lavinia Paternoster

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis

A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

A genome-wide association study of body mass index across early life and childhood

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target

Adult height variants affect birth length and growth rate in children

Age-of-onset information helps identify 76 genetic variants associated with allergic disease

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study ⬇️

Association between CST3 rs2424577 Polymorphism and Corpulence Related Phenotypes during Lifetime in Populations of European Ancestry

Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity

Association between apolipoprotein E genotype and carotid intima-media thickness may suggest a specific effect on large artery atherothrombotic stroke

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

Body stature growth trajectories during childhood and the development of myopia

Cohort Profile: Nausea and vomiting during pregnancy genetics consortium (NVP Genetics Consortium).

Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications

Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study

Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5.

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Describing the application of statistical shape modelling to DXA images to quantify the shape of the proximal femur at ages 14 and 18 years in the Avon Longitudinal Study of Parents and Children

Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.

Eleven loci with new reproducible genetic associations with allergic disease risk

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

Evidence of a common causal relationship between body mass index and inflammatory skin disease: a Mendelian Randomization study

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

Genetic Epidemiology And Mendelian Randomization For Informing Disease Therapeutics: Conceptual And Methodological Challenges

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

Genetic associations with brain microbleeds: Systematic review and meta-analyses.

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

Genetic determinants of white matter hyperintensities on brain scans: a systematic assessment of 19 candidate gene polymorphisms in 46 studies in 19,000 subjects.

Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects

Genetic epidemiology and Mendelian randomization for informing disease therapeutics: Conceptual and methodological challenges

Genetic evidence of assortative mating in humans

Genetic influences on trajectories of systolic blood pressure across childhood and adolescence

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight

Genetics of depressive symptoms in adolescence

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Genome-wide association study identifies 48 common genetic variants associated with handedness

Genome-wide association study identifies 74 loci associated with educational attainment

Genome-wide association study identifies four loci associated with eruption of permanent teeth

Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances

Genome-wide association study of three-dimensional facial morphology identifies a variant in PAX3 associated with nasion position

Genome-wide associations for birth weight and correlations with adult disease

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Genome-wide population-based association study of extremely overweight young adults--the GOYA study

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohorts

Identification of novel loci associated with hip shape: a meta-analysis of genome-wide association studies

Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

Investigating causality in the association between vitamin D status and self-reported tiredness

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

Investigating the causal relationship between allergic disease and mental health

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.

Maternal and fetal genetic contribution to gestational weight gain

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors