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List of works by Adriano Aguzzi

A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

article

A case-control study of sporadic Creutzfeldt-Jakob disease in Switzerland: analysis of potential risk factors with regard to an increased CJD incidence in the years 2001-2004.

scientific article published on 14 January 2009

A crucial role for B cells in neuroinvasive scrapie

scientific article published on 01 February 1999

A crucial role for B cells in neuroinvasive scrapie.

scientific article published in December 1997

A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body-like pathology

scientific article published on 01 June 2019

A lymphotoxin-driven pathway to hepatocellular carcinoma

scientific article published on October 2009

A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain.

scientific article

A molecular switch controls interspecies prion disease transmission in mice

scientific article

A neuroprotective role for microglia in prion diseases

scientific article published on 16 May 2016

A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein.

scientific article

A role for astroglia in prion diseases

scientific article

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor

scientific article

A suspicious signature

scientific article published in Nature

A template for new drugs against Alzheimer's disease

scientific article published in September 2013

A versatile prion replication assay in organotypic brain slices

scientific article published on 09 December 2007

Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination

scientific journal article

Abnormal synaptic protein expression and cell death in murine scrapie.

scientific article published on 26 February 2002

Absence of the prion protein homologue Doppel causes male sterility

scientific article

Absolute Quantification of Amyloid Propagons by Digital Microfluidics

scientific article published on 3 October 2017

Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system

scientific article (publication date: 4 January 2000)

Aerosols transmit prions to immunocompetent and immunodeficient mice

scientific article published in 2011

Aerosols: an underestimated vehicle for transmission of prion diseases?

scientific article published on July 2011

Alteration of B-cell subsets enhances neuroinvasion in mouse scrapie infection

scientific article published on 16 January 2008

Altered Monoaminergic Systems and Depressive-like Behavior in Congenic Prion Protein Knock-out Mice

scientific article published in October 2015

Alzheimer A beta vaccination of rhesus monkeys (Macaca mulatta).

scientific article

Alzheimer's Abeta vaccination of rhesus monkeys (Macaca mulatta).

scientific article published in February 2004

Amyloid-β pathology and cerebral amyloid angiopathy are frequent in iatrogenic Creutzfeldt-Jakob disease after dural grafting

scientific article published on 26 January 2016

An R-CaMP1.07 reporter mouse for cell-type-specific expression of a sensitive red fluorescent calcium indicator

scientific article

An analytical solution to the kinetics of breakable filament assembly

scientific article

An essential function for NBS1 in the prevention of ataxia and cerebellar defects

scientific journal article

An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein

scientific article published on 01 June 2021

Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease

scientific article

Analysis of the determinants of neurotropism and neurotoxicity of HFV in transgenic mice

scientific article published on February 1996

Analysis of the human tissue-type plasminogen activator gene promoter activity during embryogenesis of transgenic mice and rats

article

Analysis of the prion protein in primates reveals a new polymorphism in codon 226 (Y226F).

scientific article published in June 2002

Antiprion immunotherapy: to suppress or to stimulate?

scientific article published in September 2004

Antiprion prophylaxis by gene transfer of a soluble prion antagonist

scientific article published on 27 March 2008

Approaches to therapy of prion diseases

scientific article

Association between deposition of beta-amyloid and pathological prion protein in sporadic Creutzfeldt-Jakob disease

scientific article

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie

scientific article

Atypical prion protein conformation in familial prion disease with PRNP P105T mutation

scientific article published on 28 September 2010

Autoantibodies against the prion protein in individuals with PRNP mutations

scientific article published on 25 February 2020

Axonal prion protein is required for peripheral myelin maintenance

scientific article

BSE-associated prion-amyloid cardiomyopathy in primates

scientific article

Bacterial colitis increases susceptibility to oral prion disease

scientific article

Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion

scientific article

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

scientific article

Between cows and monkeys

scientific article published in June 1996

Beyond the prion principle

scientific article published in Nature

Binding of disease-associated prion protein to plasminogen

scientific article published in November 2000

Blood simple prion diagnostics

article by Adriano Aguzzi published March 2001 in Nature Medicine

Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob disease

scientific article published on October 1997

Canine MDCK cell lines are refractory to infection with human and mouse prions

scientific article

Cannibals and garbage piles

scientific article published in Nature

Cell Biology of Prions and Prionoids: A Status Report

scientific article published on 28 September 2015

Cell biology. Prion toxicity: all sail and no anchor

scientific article

Cells and prions: a license to replicate

scientific article published on 13 June 2009

Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre study over 10 years

scientific article

Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies

scientific article

Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease

scientific article published on 7 March 2006

Chapter 10 Prions

Chapter 7 A Neuropathologist's Diary

Characterizing follicular dendritic cells: A progress report

scientific article

Chemical and biophysical insights into the propagation of prion strains.

scientific article published on 13 October 2008

Chronic Lymphocytic Inflammation Specifies the Organ Tropism of Prions

scientific article published in Science

Chronic subclinical prion disease induced by low-dose inoculum

scientific article

Chronic wasting disease

scientific article

Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.

scientific article published on April 2005

Clinical and radiological mimicry of vCJD in a valine homozygous PrP(Sc) type 1 sCJD patient

scientific article published in April 2003

Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease

scientific article published in December 2005

Coincident scrapie infection and nephritis lead to urinary prion excretion

scientific article

Complement facilitates early prion pathogenesis

scientific article published in April 2001

Correction: Aerosols transmit prions to immunocompetent and immunodeficient mice

scientific article published on 12 February 2016

Corrigendum to “Transcriptional Stability of Cultured Cells upon Prion Infection” [J. Mol. Biol. 375 (2008) 1222–1233]

scholarly article published in Journal of Molecular Biology

Creutzfeldt-Jakob disease and inclusion body myositis: abundant disease-associated prion protein in muscle

scientific article

Crystallization and preliminary X-ray diffraction analysis of prion protein bound to the Fab fragment of the POM1 antibody

scientific article published on 24 September 2011

Current concepts and controversies in prion immunopathology

scientific article published on January 2004

Cystatin F is a biomarker of prion pathogenesis in mice

scientific article

Dangerous liaisons between a microbe and the prion protein

scientific article published on July 2003

De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis

scientific article

Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase

scientific article published on November 1994

Degeneration of the cerebellar granule cell layer in transgenic mice expressing genes of human foamy virus

scientific article published in February 1998

Deletions in the spinal muscular atrophy gene region in a newborn with neuropathy and extreme generalized muscular weakness

article

Deregulated expression of PAX5 in medulloblastoma

scientific article

Detection of JC virus by anti-VP1 immunohistochemistry in brains with progressive multifocal leukoencephalopathy.

scientific article published in September 1997

Developmental divergence of sensory stimulus representation in cortical interneurons

scientific article published on 12 November 2020

Differential Toxicity of Antibodies to the Prion Protein

scientific article published on 28 January 2016

Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions

scholarly article

Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice

scholarly article

Distal axonopathy in peripheral nerves of PMP22-mutant mice

scientific article

Distinct phases of cryogenic tissue damage in the cerebral cortex of wild-type and c-fos deficient mice

scientific article published on 01 December 1999

EBV renders B cells susceptible to HIV-1 in humanized mice

scientific article published on 23 June 2020

Early and rapid engraftment of bone marrow-derived microglia in scrapie.

scientific article published in November 2006

Efficient amyloid A clearance in the absence of immunoglobulins and complement factors

scientific article published on 21 February 2013

Efficient generation of multipotent mesenchymal stem cells from umbilical cord blood in stroma-free liquid culture

scientific article

Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer

scientific article published on 8 December 2004

Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells.

scientific article

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

scientific article

Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway

scientific article

Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.

scientific article published on February 1994

Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner

scientific article

Engulfment of prions in the germinal centre

scientific article published on 01 February 2000

Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads

scientific article published on 12 September 2019

Enhanced susceptibility of Prnp-deficient mice to kainate-induced seizures, neuronal apoptosis, and death: Role of AMPA/kainate receptors

scientific article published in September 2007

Enteroglial and neuronal involvement without apparent neuron loss in ileal enteric nervous system plexuses from scrapie-affected sheep

article

Erratum

scholarly article published in Histochemistry and Cell Biology

Erratum: CORRIGENDUM: Experimental autoimmune encephalomyelitis repressed by microglial paralysis

scholarly article published in Nature Medicine

Erratum: c-Jun is essential for normal mouse development and hepatogenesis

scientific article published in Nature

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

scientific journal article

Evaluation of OPEN zinc finger nucleases for direct gene targeting of the ROSA26 locus in mouse embryos

scientific article

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

scientific article published on 23 January 2005

Experimental verification of a traceback phenomenon in prion infection

scientific article

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

scientific article published in April 1998

Expression of lymphotoxin beta governs immunity at two distinct levels

scientific article published in August 2006

Expression of the interferon-induced MxA protein in viral encephalitis

scientific article published in June 2003

Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia

scientific article

Extended characterization of the novel co-isogenic C57BL/6J Prnp-/- mouse line

scientific article published in March 2017

Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease

scientific article

Fibrillar prion peptide PrP(106-126) treatment induces Dab1 phosphorylation and impairs APP processing and Abeta production in cortical neurons

scientific article published on 16 February 2008

Five questions on prion diseases

scientific article

Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8

scientific article

Follicular dendritic cells emerge from ubiquitous perivascular precursors

scientific article published on July 2012

Follicular dendritic cells: origin, phenotype, and function in health and disease

scientific article published on 03 December 2013

Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

scientific article

Functionally relevant domains of the prion protein identified in vivo

scientific article

GPR56/ADGRG1 regulates development and maintenance of peripheral myelin.

scientific article

Games played by rogue proteins in prion disorders and Alzheimer's disease

scientific article published on October 2003

Gene transfer using replication-defective human foamy virus vectors

scientific article published on August 1997

Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs

scientific article published in May 2003

Genetic and environmental factors in the etiology of human brain tumors

scientific article published on December 1995

Genetic depletion of complement receptors CD21/35 prevents terminal prion disease in a mouse model of chronic wasting disease

scientific article

Genetic prion disease: the EUROCJD experience

scientific article published on 15 November 2005

Genome-wide identification of microRNAs regulating the human prion protein

scientific article published on 21 December 2018

Genome-wide transcriptomics identifies an early preclinical signature of prion infection

scientific article published on 29 June 2020

Germinal center B cells are dispensable in prion transport and neuroinvasion

scientific article published on 26 October 2007

Gliosarcoma: an immunohistochemical study.

scientific article published in January 1989

Globular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversion

scientific article

Grafting mouse brains: from neurocarcinogenesis to neurodegeneration.

scientific article

Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease

scientific article

Heightened incidence of sporadic Creutzfeldt-Jakob disease is associated with a shift in clinicopathological profiles

scientific article

Host-microbe interactions: viruses a never-ending creativity contest

scientific article published in August 2004

Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein

scientific article published in November 2001

Human prion diseases: epidemiology and integrated risk assessment

scientific article published in December 2003

Human prion diseases: molecular and clinical aspects

scientific article

Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection.

scholarly article

Hydrogen/deuterium exchange mass spectrometry identifies two highly protected regions in recombinant full-length prion protein amyloid fibrils

scientific article

IL-6 is required for glioma development in a mouse model

scientific article published in April 2004

Iatrogenic and sporadic Creutzfeldt-Jakob disease in 2 sisters without mutation in the prion protein gene

scientific article published on 03 December 2015

Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma

scientific article

Identification of pol-related gene products of human foamy virus

scientific article published on January 1993

Immune system and peripheral nerves in propagation of prions to CNS.

scientific article published on January 2003

Immunity against prions?

Immunity against prions?

article

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

scientific article (publication date: 19 May 2000)

Improved in situ ?-galactosidase staining for histological analysis of transgenic mice

article

In Vivo Longitudinal (1)H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T.

scientific article published on 23 July 2015

Incidence of Creutzfeldt-Jakob disease in Switzerland

scientific article published in The Lancet

Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation

scholarly article

Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity.

scientific article published on 27 November 2017

Insertional mutagenesis of preneoplastic astrocytes by Moloney murine leukemia virus

scientific article published on April 2001

Insights into prion strains and neurotoxicity

scientific article published on July 2007

Intrinsic Toxicity of Antibodies to the Globular Domain of the Prion Protein

article

Intrinsic resistance of oligodendrocytes to prion infection.

scientific article published in June 2004

Introduction to Prion Disorders

Itch suppression in mice and dogs by modulation of spinal α2 and α3GABA receptors

scientific article published in Nature Communications

LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies

scientific article published on 26 July 2021

Lethal recessive myelin toxicity of prion protein lacking its central domain

scientific article

Letters to the Editor

Lines of murine oligodendroglial precursor cells immortalized by an activated neu tyrosine kinase show distinct degrees of interaction with axons in vitro and in vivo.

scientific article published on June 1995

Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells

scientific article

Lymphocyte activation gene 3 (Lag3) expression is increased in prion infections but does not modify disease progression

scientific article published in Scientific Reports

Lymphocyte activation gene 3 (Lag3) expression is increased in prion infections but does not modify disease progression

article

Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

scientific article published on 25 January 2004

Lymphotoxin β receptor signaling promotes development of autoimmune pancreatitis

scientific article

Lymphotoxin, but not TNF, is required for prion invasion of lymph nodes

scientific article

Lymphotoxin-Dependent Prion Replication in Inflammatory Stromal Cells of Granulomas

Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes

article

Mammalian prion biology: one century of evolving concepts

scientific article published on January 2004

Mice devoid of PrP are resistant to scrapie

scientific article

Microglia in prion diseases

scientific article published on 17 July 2017

Microglia: scapegoat, saboteur, or something else?

scientific article published on January 2013

Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.

scientific article published on 9 April 2010

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

scientific article

Mimicry of variant Creutzfeldt-Jakob disease by sporadic Creutzfeldt-Jakob disease: importance of the pulvinar sign

scientific article published in March 2004

Modifiers of prion protein biogenesis and recycling identified by a highly parallel endocytosis kinetics assay

scientific article published on 24 March 2017

Modulation of signal transduction through the cellular prion protein is linked to its incorporation in lipid rafts

scientific article

Molecular genetic analysis of glucocorticoid signaling during mouse development

scientific article published on January 1995

Molecular mechanisms of prion pathogenesis

scientific article published on January 2008

Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada

scientific article published in May 2005

Movement disorders reveal Creutzfeldt-Jakob disease

scientific article published in April 2009

Multiple substitutions of methionine 129 in human prion protein reveal its importance in the amyloid fibrillation pathway

scientific article published on 5 June 2012

Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

scientific article

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

scientific article published on 12 August 2017

Neuro-immune connection in spread of prions in the body?

scientific article published in The Lancet

Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP

scientific article

Neurodegeneration enters the era of functional genomics

scientific article published on 07 September 2023

Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication

scientific article

New and emerging roles of small RNAs in neurodegeneration, muscle, cardiovascular and inflammatory diseases

scientific article

No influence of amyloid-beta-degrading neprilysin activity on prion pathogenesis

scientific article

No propagation of prions in mice devoid of PrP.

scientific article published in July 1994

No superoxide dismutase activity of cellular prion protein in vivo

scientific article published in September 2003

Normal host prion protein necessary for scrapie-induced neurotoxicity

scientific article published in January 1996

Novel dominant-negative prion protein mutants identified from a randomized library

scientific article

Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses

scientific article

Olfactory behavior and physiology are disrupted in prion protein knockout mice

scientific article published on 21 December 2008

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

scientific article published on February 2001

Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes

scientific article published on April 2003

Ossified blood vessels in primary familial brain calcification elicit a neurotoxic astrocyte response

Overexpression of Pax5 is not sufficient for neoplastic transformation of mouse neuroectoderm

scientific article published on August 2001

Overexpression of lymphotoxin in T cells induces fulminant thymic involution

scientific article published on 15 May 2008

Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies

scientific article

Pathogenesis of prion diseases: current status and future outlook

scientific article published on October 2006

Peripheral pathogenesis of prion diseases

scientific article

Peripheral prion pursuit

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

scientific article published on 18 January 2024

Phenotypic variation of autosomal-dominant corticobasal degeneration

scientific article published on 18 January 2012

Plasminogen binds to disease-associated prion protein of multiple species

scientific article published in June 2001

Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates

scientific article

Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria

Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion

scientific article published in Nature

Post-exposure prophylaxis after accidental prion inoculation

scientific article published on 01 November 1997

PrP expression in B lymphocytes is not required for prion neuroinvasion

article published in 1998

PrP(106-126) activates neuronal intracellular kinases and Egr1 synthesis through activation of NADPH-oxidase independently of PrPc

scientific article published in August 2005

PrP-deficient mice are resistant to scrapie

scientific article

PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice

scientific article published on May 1999

PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain

scientific article published in September 1997

PrPSc in mammary glands of sheep affected by scrapie and mastitis

Preclinical deposition of pathological prion protein in muscle of experimentally infected primates

scientific article

Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies.

scientific article

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies

scientific article published on 6 September 2001

Prion Diseases

article

Prion Diseases

Prion Topology and Toxicity

article

Prion biology: the quest for the test

scientific article published in August 2007

Prion depletion and preservation of biological activity by preparative chaotrope ultracentrifugation

scientific article published on 30 August 2008

Prion diseases

article from 1998

Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis

scientific article published on June 2006

Prion infection, transmission, and cytopathology modeled in a low-biohazard human cell line

scientific article published on 30 June 2020

Prion infections, blood and transfusions

scientific article published on June 2006

Prion pathogenesis in the absence of NLRP3/ASC inflammasomes

scientific article (publication date: 2015)

Prion pathogenesis in the absence of Toll-like receptor signalling

scientific article

Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures.

scientific article

Prion pathogenesis is unaltered in a mouse strain with a permeable blood-brain barrier

scientific article published on 29 November 2018

Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling

scientific article

Prion propagation in mice lacking central nervous system NF- B signalling

Prion propagation, toxicity and degradation

scientific article published on 26 June 2012

Prion protein and Abeta-related synaptic toxicity impairment

scientific article

Prion protein expression in different species: analysis with a panel of new mAbs

scientific article

Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein

scientific article published on 28 March 2009

Prion research: the next frontiers

scientific article published in October 1997

Prion science and its unsung heroes

scientific article published on 18 January 2024

Prion strain discrimination using luminescent conjugated polymers

Prion transmission prevented by modifying the β2-α2 loop structure of host PrPC

scientific article published on January 2014

Prions and lymphoid organs: solved and remaining mysteries

scientific article published on 28 January 2013

Prions and peripheral nerves: a deadly rendezvous

scientific article published on September 2007

Prions and the immune system: a journey through gut, spleen, and nerves

scientific article published on January 2003

Prions and the lymphoreticular system.

scientific article

Prions, cytokines, and chemokines: a meeting in lymphoid organs

scientific article

Prions, prionoids and pathogenic proteins in Alzheimer disease

scientific article published on 03 December 2012

Prions, prionoids and protein misfolding disorders

scientific article

Prions--role of the peripheral nervous system.

scientific article

Prions: health scare and biological challenge.

scientific article

Prions: protein aggregation and infectious diseases

scientific article published on October 2009

Progress and problems in the biology, diagnostics, and therapeutics of prion diseases

scientific article

Progress and problems in the biology, diagnostics, and therapeutics of prion diseases

Proper axonal distribution of PrP(C) depends on cholesterol-sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons

scientific article

Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein

scientific article

Protective anti-prion antibodies in human immunoglobulin repertoires

scientific article published on 10 August 2020

Protein Aggregation in Neurodegeneration

article

Protein aggregation diseases: pathogenicity and therapeutic perspectives

scientific article

Protein conformation dictates prion strain ⬇️

scientific article published on October 1, 1998

Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci.

scientific article

Randomized Tree Ensembles for Object Detection in Computational Pathology

scholarly article by Thomas J. Fuchs et al published 2009 in Lecture Notes in Computer Science

Recent advances in prion biology

scientific article published on June 2004

Recent developments in prion immunotherapy

scientific article published in October 2004

Reconstructing prions: fibril assembly from simple yeast to complex mammals

scientific article published on January 2005

Recurrent intracerebral haemorrhage after coitus: a case report of sporadic cerebral amyloid angiopathy in a younger patient

Reflective multi-immersion microscope objectives inspired by the Schmidt telescope

scientific article published in 2023

Regulated expression of amyloidogenic immunoglobulin light chains in mice

Repetitive immunization enhances the susceptibility of mice to peripherally administered prions

scientific article

Ribosomal profiling during prion disease uncovers progressive translational derangement in glia but not in neurons

scientific article published on 22 September 2020

SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease

scientific article published on 06 March 2019

SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells

scientific article published on 21 October 2013

Secondary manifestation of medulloblastoma: metastases and local recurrences in 66 patients

scientific article

Sheep with scrapie and mastitis transmit infectious prions through the milk

scientific article

Short-chain acyl-CoA dehydrogenase deficiency in a 16-year-old girl with severe muscle wasting and scoliosis

scientific article published on 01 July 1997

Shrinking prions: new folds to old questions

Similar turnover and shedding of the cellular prion protein in primary lymphoid and neuronal cells

scientific article published on 24 September 2001

Single-molecule imaging reveals that small amyloid-β1-42 oligomers interact with the cellular prion protein (PrP(C))

scientific article

Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease

scientific article published in May 2006

Sleepless in Bologna: transmission of fatal familial insomnia

scientific article

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

scientific article

Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport

scientific article published on September 2016

Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease

scientific article published in April 2003

Spongiform encephalopathies. The prion's perplexing persistence

scientific article published in April 1998

Spongiform encephalopathy in transgenic mice expressing a point mutation in the β2-α2 loop of the prion protein

scientific article

Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging

scientific article published on 3 March 2005

Staining, straining and restraining prions

Stimulation of plasminogen activation by recombinant cellular prion protein is conserved in the NH2-terminal fragment PrP23-110.

scientific article published in May 2003

Strain fidelity of chronic wasting disease upon murine adaptation ⬇️

scientific article

Strictly co-isogenic C57BL/6J-Prnp −/− mice: A rigorous resource for prion science.

scientific article published in March 2016

Strictly co-isogenic C57BL/6J-Prnp-/- mice: A rigorous resource for prion science

scientific article published on 29 February 2016

Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis

article

Structural basis of prion inhibition by phenothiazine compounds

scientific article

Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion

scientific article published on 22 March 2018

Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1

scientific article

Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy

scientific article

Structure-based drug design identifies polythiophenes as antiprion compounds

scientific article

Superresolution imaging of amyloid fibrils with binding-activated probes

scientific article published on 22 April 2013

Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion

scientific article

Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

scientific article published on June 1994

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration

scientific journal article

The Neuroimmune Interface in Prion Diseases

scientific article published on 01 October 2000

The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes

scientific article

The Priority position paper: Protecting Europe's food chain from prions

scientific article

The Proto-oncogene c-fos Mediates Apoptosis in Murine T-Lymphocytes Induced by Ionizing Radiation and Dexamethasone

scientific article published in 1997

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

scientific article published on 01 March 1997

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

scientific article (publication date: August 2014)

The amyloid-Congo red interface at atomic resolution

scientific article

The biological function of the cellular prion protein: an update

scientific article

The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

scientific article published on November 2012

The comprehensive native interactome of a fully functional tagged prion protein

scientific article

The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody

scientific article

The foamy virus family: molecular biology, epidemiology and neuropathology

scientific article published on May 1993

The heavy metal-responsive transcription factor-1 (MTF-1) is not required for neural differentiation

scientific article

The immune component of brain disease

The immunobiology of prion diseases

scientific article

The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice

scientific journal article

The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue

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The peripheral nervous system and the pathogenesis of prion diseases

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The prion gene is associated with human long-term memory

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The prion hypothesis and the human prion diseases

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The prion organotypic slice culture assay—POSCA

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The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

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The prion protein knockout mouse: a phenotype under challenge

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The prion's elusive reason for being

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The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration

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The role of the NADPH oxidase NOX2 in prion pathogenesis

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The shifting biology of prions ⬇️

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The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease

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The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

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The transcellular spread of cytosolic amyloids, prions, and prionoids

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Total removal of a primary intracranial squamous cell carcinoma invading the brain stem

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Toward Therapy of Human Prion Diseases

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Transcriptional stability of cultured cells upon prion infection

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Transepithelial prion transport by M cells

Transgenic and knockout mice in the study of neurodegenerative diseases

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Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology

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Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains

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Truncated Prion Protein and Doppel Are Myelinotoxic in the Absence of Oligodendrocytic PrPC

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Tyrosinase is a new marker for cell populations in the mouse neural tube

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Unaltered Prion Pathogenesis in a Mouse Model of High-Fat Diet-Induced Insulin Resistance

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Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein

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Understanding the diversity of prions

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Unexpected tolerance of alpha-cleavage of the prion protein to sequence variations

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Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau.

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Unraveling prion strains with cell biology and organic chemistry

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Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence

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Urinary alpha1-antichymotrypsin: a biomarker of prion infection

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Utilisation de souris génétiquement modifiées dans les recherches sur les prions *

Variant Creutzfeldt-jakob disease: between lymphoid organs and brain

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X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins

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ZyFISH: a simple, rapid and reliable zygosity assay for transgenic mice

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c-Jun is essential for normal mouse development and hepatogenesis

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p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

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vCJD tissue distribution and transmission by transfusion--a worst-case scenario coming true?

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