List of works - Gerard Cagney

126. Altered Complement and Coagulation Cascade in Age 11 Children Precedes to the Onset of Psychotic Disorder.

scientific article published on 20 March 2017

32.4 ALTERED COMPLEMENT PATHWAY PROTEIN EXPRESSION IS ASSOCIATED WITH PSYCHOTIC EXPERIENCES AT AGE 11 WHICH PERSIST AT AGE 18.

scientific article published in April 2018

A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model.

scientific article published on 12 September 2017

A Central Resource for Platelet Proteomics

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

scientific article published in April 2018

A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic Response with Bevacizumab

scientific article published on 29 December 2016

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

scientific article (publication date: 10 February 2000)

A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing

scientific article

A panoramic view of yeast noncoding RNA processing

scientific article

A skeleton of the human protein interactome

scientific article

Activity profiling of platelets by chemical proteomics.

scientific article published in January 2009

Adolescent Risperidone treatment alters protein expression associated with protein trafficking and cellular metabolism in the adult rat prefrontal cortex

scientific article published on 16 May 2014

All or nothing: protein complexes flip essentiality between distantly related eukaryotes.

scientific article

An Overview of Label-Free Quantitation Methods in Proteomics by Mass Spectrometry

Analysis of the Pseudomonas putida CA-3 proteome during growth on styrene under nitrogen-limiting and non-limiting conditions.

scientific article published on 16 July 2009

Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages

scientific article published in April 2007

Application of proteomics to the study of platelet regulatory mechanisms

scientific article published in August 2004

Blood biomarker discovery in drug-free schizophrenia: the contributionof proteomics and multiplex immunoassays

scientific article published on 22 October 2016

Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort.

scientific article

Casein Hydrolysate with Glycemic Control Properties: Evidence from Cells, Animal Models, and Humans

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

scientific article published on 20 November 2003

Chl4p and iml3p are two new members of the budding yeast outer kinetochore

scientific article

Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress

scientific article published on 11 January 2019

Comprehensive Proteomics Analysis of Polyhydroxyalkanoate (PHA) Biology in Pseudomonas putida KT2440: The Outer Membrane Lipoprotein OprL is a Newly Identified Phasin

scientific article published in 2024

Computational methods for the comparative quantification of proteins in label-free LCn-MS experiments.

scientific article published on 28 September 2007

Corrigendum: miR302 regulates SNAI1 expression to control mesangial cell plasticity

scientific article published on 14 February 2017

Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore

scientific article

Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation

scientific article published on 15 February 2016

De novo peptide sequencing and quantitative profiling of complex protein mixtures using mass-coded abundance tagging

scientific article published in February 2002

Detailed Identification of Plasma Proteins Adsorbed on Copolymer Nanoparticles

scientific article published on 01 January 2007

Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs

scientific article

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

scientific article published on 15 September 2016

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

scientific article published on 21 April 2016

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

scientific article published on September 2017

Ensemble non-negative matrix factorization methods for clustering protein-protein interactions.

scientific article published on 12 June 2008

Epigenetic Factors in Schizophrenia: Mechanisms and Experimental Approaches

scientific article published on 15 February 2019

Epistatic relationships reveal the functional organization of yeast transcription factors

scientific article

Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.

scientific article published on 29 May 2017

Functional characterisation of the YIPF protein family in mammalian cells

scientific article published on 20 December 2016

Functional genomics of the yeast DNA-damage response

scientific article published on January 2006

Functional organization of the S. cerevisiae phosphorylation network

scientific article

Global landscape of HIV-human protein complexes

scientific article

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

scientific article

HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells

scientific article published on January 2010

Hierarchical modularity and the evolution of genetic interactomes across species.

scientific article

High-definition macromolecular composition of yeast RNA-processing complexes

scientific article

High-throughput screening for protein-protein interactions using yeast two-hybrid arrays

scientific article

Host cell factors in HIV replication: meta-analysis of genome-wide studies

scientific article

Human Proteinpedia enables sharing of human protein data

scientific article

Human tissue profiling with multidimensional protein identification technology

scientific article

Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques

scientific article published on 14 August 2008

Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

scientific article

Improved functional overview of protein complexes using inferred epistatic relationships.

scientific article

Imputing and predicting quantitative genetic interactions in epistatic MAPs.

scientific article published on January 2011

In silico proteome analysis to facilitate proteomics experiments using mass spectrometry

scientific article

Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.

scientific article published on 20 October 2015

Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children

scientific article published on 30 January 2019

Interaction networks: lessons from large-scale studies in yeast

scientific article published on October 2009

Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila

scientific article published on 13 August 2013

Investigating the in vivo activity of the DeaD protein using protein-protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs

scientific article published on February 2007

Large-scale functional analysis using peptide or protein arrays.

scientific article

Machine learning based prediction and the influence of complement – Coagulation pathway proteins on clinical outcome: Results from the NEURAPRO trial

scientific article published in 2022

Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence.

scientific article published on 13 January 2015

Missing value imputation for epistatic MAPs

scientific article

Moderation of the platelet releasate response by aspirin

scientific article (publication date: June 2007)

Native gel analysis of macromolecular protein complexes in cultured mammalian cells

scientific article published on 29 July 2015

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

scientific article

Nimesulide 90 mg orally twice daily does not influence postoperative morphine requirements after major chest surgery

scientific article published in January 2008

O1.1 ALTERED COMPLEMENT PATHWAY PROTEIN EXPRESSION IS ASSOCIATED WITH PSYCHOTIC EXPERIENCES AT AGE 11 WHICH PERSIST AT AGE 18.

scientific article

O1.7. PROTEOMIC ANALYSIS OF BLOOD BASED SAMPLES FROM THE OPTiMiSE (OPTIMIZATION OF TREATMENT AND MANAGEMENT OF SCHIZOPHRENIA IN EUROPE) STUDY POINT TOWARDS COMPLEMENT PATHWAY PROTEIN CHANGES.

scientific article published in April 2018

Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus

scientific article published on 28 October 2013

Optimal stepwise experimental design for pairwise functional interaction studies

scientific article published on 18 September 2008

Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation

scientific article

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

scientific journal article

Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal

scientific journal article

Proteasome Involvement in the Repair of DNA Double-Strand Breaks

Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression.

scientific article

Proteomic analysis of the postsynaptic density implicates synaptic function and energy pathways in bipolar disorder

scientific article published on 29 November 2016

Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia

scientific article published on 22 July 2014

Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate

scientific article

Quantitative genetic interactions reveal biological modularity

scientific article published on May 2010

Quantitative genetic-interaction mapping in mammalian cells

scientific article published on 13 February 2013

RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach

scientific article

Reduced protein synthesis in schizophrenia patient-derived olfactory cells

scientific article published on 20 October 2015

Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint

scientific article

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18

scientific article published on 10 May 2019

Sequential interval motif search: unrestricted database surveys of global MS/MS data sets for detection of putative post-translational modifications

scientific article

Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia

scientific article published on December 2010

SpecAlign--processing and alignment of mass spectra datasets.

scientific article published on 2 February 2005

Targeted proteomics for validation of biomarkers in early psychosis

scientific article published on 22 November 2013

The Effects of Prenatal Iron Deficiency and Risperidone Treatment on the Rat Frontal Cortex: A Proteomic Analysis

scientific article

The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.

scientific article published on 22 March 2018

The effect of polyphosphate kinase gene deletion on polyhydroxyalkanoate accumulation and carbon metabolism in Pseudomonas putida KT2440.

scientific article

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis

scientific journal article

Three novel proteins co-localise with polyhydroxybutyrate (PHB) granules in Rhodospirillum rubrum S1.

scientific article published in March 2018

Understanding the physiological roles of polyhydroxybutyrate (PHB) in Rhodospirillum rubrum S1 under aerobic chemoheterotrophic conditions.

scientific article

miR302 regulates SNAI1 expression to control mesangial cell plasticity

scientific article published on 14 February 2017

msmsEval: tandem mass spectral quality assignment for high-throughput proteomics.

scientific article

List of works by Gerard Cagney

126. Altered Complement and Coagulation Cascade in Age 11 Children Precedes to the Onset of Psychotic Disorder.

32.4 ALTERED COMPLEMENT PATHWAY PROTEIN EXPRESSION IS ASSOCIATED WITH PSYCHOTIC EXPERIENCES AT AGE 11 WHICH PERSIST AT AGE 18.

A Brain-Derived Neurotrophic Factor Mimetic Is Sufficient to Restore Cone Photoreceptor Visual Function in an Inherited Blindness Model.

A Central Resource for Platelet Proteomics

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

A Quininib Analogue and Cysteinyl Leukotriene Receptor Antagonist Inhibits Vascular Endothelial Growth Factor (VEGF)-independent Angiogenesis and Exerts an Additive Antiangiogenic Response with Bevacizumab

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing

A panoramic view of yeast noncoding RNA processing

A skeleton of the human protein interactome

Activity profiling of platelets by chemical proteomics.

Adolescent Risperidone treatment alters protein expression associated with protein trafficking and cellular metabolism in the adult rat prefrontal cortex

All or nothing: protein complexes flip essentiality between distantly related eukaryotes.

An Overview of Label-Free Quantitation Methods in Proteomics by Mass Spectrometry

Analysis of the Pseudomonas putida CA-3 proteome during growth on styrene under nitrogen-limiting and non-limiting conditions.

Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages

Application of proteomics to the study of platelet regulatory mechanisms

Blood biomarker discovery in drug-free schizophrenia: the contributionof proteomics and multiplex immunoassays

Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort.

Casein Hydrolysate with Glycemic Control Properties: Evidence from Cells, Animal Models, and Humans

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

Chl4p and iml3p are two new members of the budding yeast outer kinetochore

Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress

Comprehensive Proteomics Analysis of Polyhydroxyalkanoate (PHA) Biology in Pseudomonas putida KT2440: The Outer Membrane Lipoprotein OprL is a Newly Identified Phasin

Computational methods for the comparative quantification of proteins in label-free LCn-MS experiments.

Corrigendum: miR302 regulates SNAI1 expression to control mesangial cell plasticity

Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore

Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation

De novo peptide sequencing and quantitative profiling of complex protein mixtures using mass-coded abundance tagging

Detailed Identification of Plasma Proteins Adsorbed on Copolymer Nanoparticles

Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

Ensemble non-negative matrix factorization methods for clustering protein-protein interactions.

Epigenetic Factors in Schizophrenia: Mechanisms and Experimental Approaches

Epistatic relationships reveal the functional organization of yeast transcription factors

Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.

Functional characterisation of the YIPF protein family in mammalian cells

Functional genomics of the yeast DNA-damage response

Functional organization of the S. cerevisiae phosphorylation network

Global landscape of HIV-human protein complexes

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells

Hierarchical modularity and the evolution of genetic interactomes across species.

High-definition macromolecular composition of yeast RNA-processing complexes

High-throughput screening for protein-protein interactions using yeast two-hybrid arrays

Host cell factors in HIV replication: meta-analysis of genome-wide studies

Human Proteinpedia enables sharing of human protein data

Human tissue profiling with multidimensional protein identification technology

Identification of Apolipoprotein AI as a serum biomarker of chronic kidney disease in liver transplant recipients, using proteomic techniques

Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods

Improved functional overview of protein complexes using inferred epistatic relationships.

Imputing and predicting quantitative genetic interactions in epistatic MAPs.

In silico proteome analysis to facilitate proteomics experiments using mass spectrometry

Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.

Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children

Interaction networks: lessons from large-scale studies in yeast

Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila

Investigating the in vivo activity of the DeaD protein using protein-protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs

Large-scale functional analysis using peptide or protein arrays.

Machine learning based prediction and the influence of complement – Coagulation pathway proteins on clinical outcome: Results from the NEURAPRO trial

Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence.

Missing value imputation for epistatic MAPs

Moderation of the platelet releasate response by aspirin

Native gel analysis of macromolecular protein complexes in cultured mammalian cells

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

Nimesulide 90 mg orally twice daily does not influence postoperative morphine requirements after major chest surgery

O1.1 ALTERED COMPLEMENT PATHWAY PROTEIN EXPRESSION IS ASSOCIATED WITH PSYCHOTIC EXPERIENCES AT AGE 11 WHICH PERSIST AT AGE 18.

O1.7. PROTEOMIC ANALYSIS OF BLOOD BASED SAMPLES FROM THE OPTiMiSE (OPTIMIZATION OF TREATMENT AND MANAGEMENT OF SCHIZOPHRENIA IN EUROPE) STUDY POINT TOWARDS COMPLEMENT PATHWAY PROTEIN CHANGES.

Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus

Optimal stepwise experimental design for pairwise functional interaction studies

Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal

Proteasome Involvement in the Repair of DNA Double-Strand Breaks

Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression.

Proteomic analysis of the postsynaptic density implicates synaptic function and energy pathways in bipolar disorder

Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia