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List of works by Federico Cappuzzo

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

scientific article
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

scientific article
First-line crizotinib versus chemotherapy in ALK-positive lung cancer

scientific article
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

scientific article
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial

scientific article
Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study.

scientific article published on 20 May 2010
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

scientific article
Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

scientific article
Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial.

scientific article
Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab

scientific article
PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients

scientific article published on 28 October 2014
Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial

scientific article
Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer

scientific article published on 3 October 2011
Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients

scientific article published in August 2005
Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib.

scientific article published on 22 February 2007
Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop

scientific article published on October 2010
MET increased gene copy number and primary resistance to gefitinib therapy in non-small-cell lung cancer patients.

scientific article published on 03 October 2008
EGFR FISH assay predicts for response to cetuximab in chemotherapy refractory colorectal cancer patients

scientific article published on 31 October 2007
Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: results from the EUROS1 cohort

scientific article
Predictive value of EGFR and HER2 overexpression in advanced non-small-cell lung cancer

scientific article published on August 2009
Genetic activation of the MET pathway and prognosis of patients with high-risk, radically resected gastric cancer

scientific article published on 31 October 2011
Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): a randomized, phase II study

scientific article
Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors

scientific article
Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients

scientific article published on 24 June 2008
Prospective Study of Gefitinib in Epidermal Growth Factor Receptor Fluorescence In Situ Hybridization–Positive/Phospho-Akt–Positive or Never Smoker Patients With Advanced Non–Small-Cell Lung Cancer: The ONCOBELL Trial

scientific article published on 01 June 2007
Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

scientific article
HER2 mutation and response to trastuzumab therapy in non-small-cell lung cancer

scientific article published on 01 June 2006
Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma

scientific article
Role of gemcitabine in cancer therapy

scientific article
Gefitinib in pretreated non-small-cell lung cancer (NSCLC): analysis of efficacy and correlation with HER2 and epidermal growth factor receptor expression in locally advanced or metastatic NSCLC.

scientific article
Lung cancer patients with HER2 mutations treated with chemotherapy and HER2-targeted drugs: results from the European EUHER2 cohort

scientific article
EGFR-mutated oncogene-addicted non-small cell lung cancer: current trends and future prospects

scientific article
Lung cancer screening with spiral CT: baseline results of the randomized DANTE trial.

scientific article published on 23 October 2007
EGFR fluorescence in situ hybridisation assay: guidelines for application to non-small-cell lung cancer

scientific article
Epidermal growth factor receptor inhibition in lung cancer: status 2012.

scientific article published on March 2013
Increased MET and HGF gene copy numbers are associated with trastuzumab failure in HER2-positive metastatic breast cancer

scientific article
Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating epidermal growth factor receptor mutation: Review of the evidence

scientific article published on 08 January 2011
Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients.

scientific article
Survival benefit with erlotinib maintenance therapy in patients with advanced non-small-cell lung cancer (NSCLC) according to response to first-line chemotherapy.

scientific article published on 24 May 2011
EGFR and HER2 Gene Copy Number and Response to First-Line Chemotherapy in Patients with Advanced Non-small Cell Lung Cancer (NSCLC)

article
Prognostic and predictive value of K-RAS mutations in non-small cell lung cancer

scientific article published on June 2012
Epidermal growth factor receptor targeted therapy by ZD 1839 (Iressa) in patients with brain metastases from non-small cell lung cancer (NSCLC).

scientific article published in August 2003
Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer.

scientific article
microRNA classifiers are powerful diagnostic/prognostic tools in ALK-, EGFR-, and KRAS-driven lung cancers

scientific article
Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib

scientific article published on 06 April 2006
Let-7g and miR-21 expression in non-small cell lung cancer: Correlation with clinicopathological and molecular features

scientific article published on 02 July 2013
Gemcitabine and vinorelbine in pemetrexed-pretreated patients with malignant pleural mesothelioma

scientific article
Randomized phase II study of danusertib in patients with metastatic castration-resistant prostate cancer after docetaxel failure

scientific article published on 29 August 2012
MicroRNA signature in metastatic colorectal cancer patients treated with anti-EGFR monoclonal antibodies

scientific article
Treatment of advanced non-small-cell lung cancer with epidermal growth factor receptor (EGFR) mutation or ALK gene rearrangement: results of an international expert panel meeting of the Italian Association of Thoracic Oncology

scientific article published on 27 December 2013

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