List of works by Stephen P Jackson

A Compendium of Mutational Signatures of Environmental Agents

scientific article published on 11 April 2019

A DNA damage checkpoint response in telomere-initiated senescence

scientific article (publication date: 13 November 2003)

A Heterotrimeric PCNA in the Hyperthermophilic Archaeon Sulfolobus solfataricus

scientific article published on 01 January 2003

A YAC contig encompassing the XRCC5 (Ku80) DNA repair gene and complementation of defective cells by YAC protoplast fusion

scientific article

A flow cytometry-based method to simplify the analysis and quantification of protein association to chromatin in mammalian cells

scientific article

A high-throughput in vivo micronucleus assay for genome instability screening in mice

scientific article published on 31 December 2014

A high-throughput, flow cytometry-based method to quantify DNA-end resection in mammalian cells

scientific article

A means to a DNA end: the many roles of Ku.

scientific article published on May 2004

A new X-ray sensitive CHO cell mutant of ionizing radiation group 7,XR-C2, that is defective in DSB repair but has only a mild defect in V(D)J recombination.

scientific article published on September 2000

A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair

scientific article

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

scientific article

A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.

scientific article published on 18 August 2011

A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response

scientific article published on 4 September 2014

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

scientific article

A role for TAF3B2 in the repression of human RNA polymerase III transcription in nonproliferating cells

scientific article published on 30 March 2001

A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage

scientific article

ATM and ATR.

scientific article published in June 2003

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

scientific article published in Nature Communications

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

scientific article

ATM, a central controller of cellular responses to DNA damage.

scientific article

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

scientific article (publication date: 2006)

ATM-dependent phosphorylation of heterogeneous nuclear ribonucleoprotein K promotes p53 transcriptional activation in response to DNA damage

scientific article published on 23 January 2013

Activation domains of transcription factors mediate replication dependent transcription from a minimal HIV-1 promoter

scientific article published on February 1996

Activation of the DNA damage response by telomere attrition: a passage to cellular senescence.

scientific article published on 8 May 2004

An archaebacterial homologue of the essential eubacterial cell division protein FtsZ.

scientific article published on June 1996

Analysis of the ATM protein in wild-type and ataxia telangiectasia cells

scientific article published on December 1996

Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I.

scientific article published in October 1998

Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors

scientific article published on 11 September 2020

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

scientific article

Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites

scientific article

CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination

scientific article

CDK targets Sae2 to control DNA-end resection and homologous recombination

scientific article

CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing

scientific article published on 15 April 2016

Cancer predisposition. Ataxia-telangiectasia at the crossroads

scientific article published on November 1995

Cell cycle regulation of RNA polymerase III transcription

scientific article published on December 1995

Characterization of the Residues Phosphorylated in Vitro by Different C-terminal Domain Kinases

scientific article published on 01 March 1998

Charting a course through RNA polymerase

scientific article published on 01 September 2000

Chemical inhibition of NAT10 corrects defects of laminopathic cells

scientific article

Chromatin determinants impart camptothecin sensitivity

scientific article published on 7 April 2017

Chromosomes and expression mechanisms

scientific article published on 01 April 1997

Chromothripsis and cancer: causes and consequences of chromosome shattering

scientific article published on 13 September 2012

Cleavage and inactivation of ATM during apoptosis.

scientific article

Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha

scientific article

Colworth Medal lecture. Detection, repair and signalling of DNA double-strand breaks.

scientific article

Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities

scientific article published on March 2000

Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.

scientific article

Competitive and noncompetitive inhibition of the DNA-dependent protein kinase

scientific article published on 01 June 1999

Confinement and deformation of single cells and their nuclei inside size-adapted microtubes

scientific article

Conserved functional domains of the RNA polymerase III general transcription factor BRF.

scientific article

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

scientific article (publication date: 31 March 2005)

Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks.

scientific article published on 19 September 2016

Corrigendum: Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks.

scientific article published on 13 June 2017

Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

scientific article

CtIP Mutations Cause Seckel and Jawad Syndromes

scientific article

CtIP tetramer assembly is required for DNA-end resection and repair

scientific article

DNA REPAIR. Drugging DNA repair.

scientific article published in June 2016

DNA damage detection by DNA dependent protein kinase and related enzymes.

scientific article published on January 1996

DNA damage responses at low radiation doses.

scientific article published on September 2005

DNA damage signaling in response to double-strand breaks during mitosis

scientific article published on July 2010

DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p

scientific article published in September 1999

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

scientific article published on October 1995

DNA double-strand breaks: signaling, repair and the cancer connection

scientific article (publication date: March 2001)

DNA end-joining: from yeast to man

scientific article published on 01 October 1998

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

scientific article published on October 2008

DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement

scientific article published on July 1991

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

scientific article published on 9 January 2015

DNA repair: The Nijmegen breakage syndrome protein

DNA repair: how Ku makes ends meet.

scientific article

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

scientific article

DNA-dependent protein kinase

scientific article published on July 1997

DNA-dependent protein kinase and related proteins.

scientific article

DNA-dependent protein kinase defects are linked to deficiencies in DNA repair and V(D)J recombination

scientific article published on February 1996

DNA-dependent protein kinase gets a break: its role in repairing DNA and maintaining genomic integrity.

scientific article

DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I

scientific article published on 01 January 1995

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

scientific article

Derivation and maintenance of mouse haploid embryonic stem cells

scientific article published on 03 June 2019

Detecting, signalling and repairing DNA double-strand breaks.

scientific article

Detection of functional protein domains by unbiased genome-wide forward genetic screening

Detection of functional protein domains by unbiased genome-wide forward genetic screening.

scientific article published on 18 April 2018

Deubiquitylating enzymes and DNA damage response pathways

scientific article published on September 2013

Deubiquitylating enzymes and drug discovery: emerging opportunities.

scientific article published on 29 September 2017

Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency.

scientific article published on 04 October 2016

Differential regulation of RNA polymerases I, II, and III by the TBP-binding repressor Dr1.

scientific article published on October 1994

Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription

scientific article published on May 1991

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome

scientific article

Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis

scientific article

Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair

scientific article published on December 2007

Dma/RNF8 proteins are evolutionarily conserved E3 ubiquitin ligases that target septins

scientific article

Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation.

scientific article

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

scientific article

EDD mediates DNA damage-induced activation of CHK2

scientific article

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

scientific article published in August 2001

Erratum: PGBD5 promotes site-specific oncogenic mutations in human tumors.

scientific article published in September 2017

Evolutionary and functional conservation of the DNA non-homologous end-joining protein, XLF/Cernunnos

scientific article published on 12 October 2006

Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer

scientific article published on 01 January 2005

Expression and nuclear localization of BLM, a chromosome stability protein mutated in Bloom's syndrome, suggest a role in recombination during meiotic prophase.

scientific article

Expression of DNA-Dependent Protein Kinase Holoenzyme Upon Induction of Lymphocyte Differentiation and V(D)J Recombination

article by Ulf Grawunder et al published 1 November 1996 in FEBS Journal

Expression of Ku70 correlates with survival in carcinoma of the cervix.

scientific article published on December 2000

Extraordinary sequence conservation of the PRP8 splicing factor

scientific article

Factor requirements for transcription in the Archaeon Sulfolobus shibatae

scientific article

Fanconi anemia C gene product plays a role in the fidelity of blunt DNA end-joining

scientific article published on June 1998

Functional links between telomeres and proteins of the DNA-damage response

scientific article published in August 2004

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability

scientific article published in September 1999

G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status

scientific article

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

scientific article published on October 1990

Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8

scientific article published on August 1, 1995

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

article published in 1997

Genetic predisposition to mosaic Y chromosome loss in blood

scientific article published on 20 November 2019

Genome architecture and stability in the Saccharomyces cerevisiae knockout collection

scientific article published on 11 September 2019

Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells

scientific article published on 31 October 2016

Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway

scientific article

Genomic stability. Silencing and DNA repair connect.

scientific article

Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events

scientific article

Global genome nucleotide excision repair is organized into domains that promote efficient DNA repair in chromatin

scientific article published on 28 July 2016

Histone marks: repairing DNA breaks within the context of chromatin

scientific article published on April 2012

Human CtIP mediates cell cycle control of DNA end resection and double strand break repair

scientific journal article

Human CtIP promotes DNA end resection

scientific article

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

scientific article published on 29 August 2010

Human SIRT6 promotes DNA end resection through CtIP deacetylation

scientific article

Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis

scientific article

Human cell senescence as a DNA damage response.

scientific article

Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair

scientific article published on August 1997

Identification of a DNA nonhomologous end-joining complex in bacteria

scientific journal article

Identification of a conserved archaeal RNA polymerase subunit contacted by the basal transcription factor TFB.

scientific article

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

scientific article published on September 1996

Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions

scientific article published on 01 December 1987

Identification of the catalytic subunit of DNA dependent protein kinase as the product of the mouse scid gene

scientific article published on January 1996

Increased Genome Instability in Aging Yeast

Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway

scientific article published on 3 July 2018

Interfaces between the detection, signaling, and repair of DNA damage

scientific article

Involvement of DNA end-binding protein Ku in Ty element retrotransposition

scientific article

KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling

scientific article published on 26 May 2013

Keeping 53BP1 out of focus in mitosis

scientific article published on 9 May 2014

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

scientific journal article

Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts

Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo

scientific article

Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress

scientific article published on 01 September 2021

MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance

scientific article published on 15 November 2019

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

scientific article

MDC1 is required for the intra-S-phase DNA damage checkpoint

scientific article (publication date: 27 February 2003)

MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes

scientific article

MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53

scientific article

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

scientific article published on August 1, 1997

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

scientific article

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.

scientific article published on 11 June 2018

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

scientific article

Mechanism of TATA-binding protein recruitment to a TATA-less class III promoter

scientific article published on December 1992

Mechanism of autoregulation by an archaeal transcriptional repressor

scientific article

Mechanistic analysis of RNA polymerase III regulation by the retinoblastoma protein

scientific article published on April 1997

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

scientific article published on November 1995

Mitotic regulation of a TATA-binding-protein-containing complex

scientific article published on April 1995

Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20

scientific article

Molecular and biochemical characterization of new X-ray-sensitive hamster cell mutants defective in Ku80.

scientific article published on October 1998

Molecular and biochemical characterization of xrs mutants defective in Ku80.

scientific article published on March 1997

Molecular cross-talk among chromosome fragility syndromes

scientific article published in June 2004

Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles

scientific article published on 01 April 2021

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

scientific article

On Your MARK, Get SET(D2), Go! H3K36me3 Primes DNA Mismatch Repair

scientific article published on 01 April 2013

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

scientific article

Orientation of the transcription preinitiation complex in archaea

scientific article published on November 1999

PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1

scientific article published on 10 February 2020

PGBD5 promotes site-specific oncogenic mutations in human tumors

scientific article published on 15 May 2017

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

scientific article published on 22 May 2020

Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia

scientific article published in November 2017

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

scientific article

Phosphorylation of Histone H4T80 Triggers DNA Damage Checkpoint Recovery

scientific article published on 25 October 2018

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

scientific article

Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradient

scientific article published on 27 July 2016

Protective packaging for DNA

scientific article published in Nature

Protein kinases and DNA damage

scientific article published on November 1994

Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response

scientific article

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair

scientific article published in June 2012

RNF8 links nucleosomal and cytoskeletal ubiquitylation of higher order protein structures

scientific article published on 2 April 2013

Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast

scientific article

Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.

scientific article published on 15 December 2005

Regulating transcription factor activity by phosphorylation

scientific article

Regulation of DNA damage responses by ubiquitin and SUMO.

scientific article

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

scientific article

Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair

scientific article

Regulation of Rad51 function by phosphorylation

scientific article

Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe

scientific article published on 16 March 2007

Replication stress induces 53BP1-containing OPT domains in G1 cells

scientific article

Repression of RNA polymerase III transcription by the retinoblastoma protein

scientific article published in Nature

Retraction

scientific article published on 11 April 2019

Retraction Note: KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling.

scientific article

Rolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies

scientific article

SV40 stimulates expression of the transacting factor Sp1 at the mRNA level

scientific article published on April 1990

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

scientific article

Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair

scientific article

Saccharomyces cerevisiae histone H2A Ser122 facilitates DNA repair

scientific article

Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells

scientific article published on 30 April 2009

Screening the yeast genome for new DNA-repair genes

scientific article

Sensing and repairing DNA double-strand breaks

scientific article

Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing

scientific article

Sequence-specific DNA binding by the S. shibatae TFIIB homolog, TFB, and its effect on promoter strength

scientific article

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

scientific article published on 18 July 2018

Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein.

scientific article published on 08 September 2015

Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway

scientific article published on 23 September 2019

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes

scientific article published on 5 February 2012

Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.

scientific article published on September 2016

Specific association of mouse MDC1/NFBD1 with NBS1 at sites of DNA-damage.

scientific article

Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres

scientific article published on 10 May 2007

Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2

scientific article

Structural basis for the NAD-dependent deacetylase mechanism of Sir2

scientific article

Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling

scientific article

Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode

scientific article published on 18 January 2006

Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation

scientific article

Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase

scientific article published on 17 April 2005

Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone

scientific article

Suppression of retroviral infection by the RAD52 DNA repair protein

scientific article

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

scientific article (publication date: December 1989)

Synthetic lethality between PAXX and XLF in mammalian development

scientific article published on October 2016

Synthetic viability genomic screening defines Sae2 function in DNA repair

scientific article

Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair

scientific journal article

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

scientific article published on 7 September 2014

Systematic identification of functional residues in mammalian histone H2AX

scientific article

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

scientific journal article

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.

scientific article published on 29 December 2015

Targeting DNA Repair in Cancer: Beyond PARP Inhibitors.

scientific article published on 21 December 2016

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.

scientific article published on 27 April 2018

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

scientific article (publication date: 14 April 2005)

Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant

scientific article published on March 2001

Temperature, template topology, and factor requirements of archaeal transcription

scientific article

The DNA-damage response in human biology and disease

scientific article

The DNA-damage response: new molecular insights and new approaches to cancer therapy

scientific article

The FHA domain

scientific article

The FHA domain is a modular phosphopeptide recognition motif.

scientific article

The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku.

scientific article published on January 2003

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

scientific article

The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose).

scientific article

The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair

scientific article published on 21 January 2009

The TATA-binding protein is a general transcription factor for RNA polymerase III

scientific article published on January 1, 1992

The TATA-binding protein: a central role in transcription by RNA polymerases I, II and III

scientific article published on August 1, 1992

The TATA-binding protein: a general transcription factor in eukaryotes and archaebacteria

scientific article

The archaeal TFIIEalpha homologue facilitates transcription initiation by enhancing TATA-box recognition

scientific article published on February 2001

The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

scientific article published in July 1999

The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation

scientific article

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

scientific article

The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint

scientific article published on 13 November 2006

The recognition of DNA damage

scientific article published on February 1996

The role of Ataxia telangiectasia and the DNA-dependent protein kinase in the p53-mediated cellular response to ionising radiation

scientific article published on 01 September 1996

The role of transcription factor B in transcription initiation and promoter clearance in the archaeon Sulfolobus acidocaldarius.

scientific article

The yeast Xrs2 complex functions in S phase checkpoint regulation

scientific article

TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation

scientific article

Trajectory and uniqueness of mutational signatures in yeast mutators

scientific article published on 23 September 2020

Transcription and translation in Archaea: a mosaic of eukaryal and bacterial features

scientific article

Transcription factor phosphorylation by the DNA-dependent protein kinase

scientific article

Transcription: new insights from studies on Archaea.

scientific article

Transcriptional regulation of an archaeal operon in vivo and in vitro

scientific article published on December 1999

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.

scientific article published on 23 March 2014

Tudor domains track down DNA breaks

scientific article published on 01 December 2004

USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism

scientific article

USP4 Auto-Deubiquitylation Promotes Homologous Recombination

scientific article published on 7 October 2015

Ubiquitin regulates dissociation of DNA repair factors from chromatin

scientific article published in June 2015

Ubiquitylation, neddylation and the DNA damage response

scientific article

When two is not enough: a CtIP tetramer is required for DNA repair by Homologous Recombination

scientific article published on 25 August 2015

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

scientific article

Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability

scientific article published in January 2005

Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56

scientific article

c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif

scientific article published on March 1993

gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

scientific article

hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage

scientific article published on December 2005

p53 prevents the accumulation of double-strand DNA breaks at stalled-replication forks induced by UV in human cells

scientific article