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List of works by Adrian Peter Bird

A Nuclear Protein that Binds Preferentially to Methylated DNA in vitro May Play a Role in the Inaccessibility of Methylated CpGs in Mammalian Nuclei

scientific article published on 01 January 1990

A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins

scientific article (publication date: July 1997)

A critique of the hypothesis that CA repeats are primary targets of neuronal MeCP2

scientific article published in 2022

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

scientific article published on 24 April 2015

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

scientific article published on 01 January 1985

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

scientific journal article

A mutation-led search for novel functional domains in MeCP2

A mutation-led search for novel functional domains in MeCP2.

scientific article published in July 2018

A novel CpG island set identifies tissue-specific methylation at developmental gene loci

scientific article

A study of early events in ribosomal gene amplification

scientific article published on January 1978

A temporal threshold for formaldehyde crosslinking and fixation

scientific article

A timing study of DNA amplification in Xenopus laevis oocytes

scientific article published on 01 January 1971

A unique DNA methylation signature defines a population of IFN-γ/IL-4 double-positive T cells during helminth infection.

scientific article

Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo

scientific article published on 17 February 2020

Absence of genome-wide changes in DNA methylation during development of the zebrafish

article

Active repression of methylated genes by the chromosomal protein MBD1

scientific article

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.

scientific article published on July 2013

Adrian Bird

scientific article published in June 2007

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2

scientific article published on 01 August 2018

Alternative chromatin structure at CpG islands

scientific article published on 01 March 1990

An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development

scientific article published on 13 March 2019

An alternative promoter in the mouse major histocompatibility complex class II I-Abeta gene: implications for the origin of CpG islands

scientific article

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

scientific article

Binding of histone H1 to DNA is indifferent to methylation at CpG sequences

scientific article published in November 1995

Cell type-specific DNA methylation at intragenic CpG islands in the immune system.

scientific article

Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells

scientific article

Cfp1 is required for gene expression-dependent H3K4 trimethylation and H3K9 acetylation in embryonic stem cells

scientific article published on 4 September 2014

Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

scientific article

Chicken microchromosomes are hyperacetylated, early replicating, and gene rich

scientific article

Circular ribosomal DNA and ribosomal DNA: replication in somatic amphibian cells

scientific article

Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development

scientific journal article

Coincident start sites for divergent transcripts at a randomly selected CpG-rich island of mouse

scientific article

Comparative analysis of potential broad-spectrum neuronal Cre drivers

scientific article published on 08 July 2022

Considerations when investigating lncRNA function in vivo.

scientific article

Coupled demethylation of sites in a conserved sequence of Xenopus ribosomal DNA

scientific article published on 01 January 1983

CpG Islands: A Historical Perspective

scientific article published in January 2018

CpG island libraries from human chromosomes 18 and 22: landmarks for novel genes.

scientific article

CpG islands and genes

scientific article published on June 1995

CpG islands and the regulation of transcription

scientific article (publication date: 15 May 2011)

CpG islands as genomic footprints of promoters that are associated with replication origins.

scientific article

CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

scientific article published on April 2010

CpG islands of chicken are concentrated on microchromosomes

scientific article published on March 1996

CpG islands of the pig.

scientific article

CpG islands--'a rough guide'.

scientific article published on 18 April 2009

CpG islands.

scientific article published on January 1993

CpG methylation is targeted to transcription units in an invertebrate genome

scientific article

CpG-rich islands and the function of DNA methylation

scientific article (publication date: May 1986)

DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG.

scientific article published on September 2005

DNA methylation and Rett syndrome

scientific article

DNA methylation and chromatin modification.

scientific article

DNA methylation and chromatin structure

scientific article published on July 1991

DNA methylation and the frequency of CpG in animal DNA.

scientific article

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

scientific article published on 01 March 1991

DNA methylation landscapes: provocative insights from epigenomics

scientific article (publication date: June 2008)

DNA methylation patterns and epigenetic memory

scientific article

DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution

scientific article

DNA methylation specifies chromosomal localization of MeCP2.

scientific article published on January 1996

DNA methylation versus gene expression ⬇️

article

DNA recognition by the methyl-CpG binding domain of MeCP2.

scientific article

DNAase I sensitivity and methylation of active versus inactive rRNA genes in Xenopus species hybrids

article

DNaseI-hypersensitive sites at promoter-like sequences in the spacer of Xenopus laevis and Xenopus borealis ribosomal DNA

scientific article published on August 1983

Deficiency of Mbd2 suppresses intestinal tumorigenesis

Densely methylated sequences that are preferentially localized at telomere-proximal regions of human chromosomes

scientific article

Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons

scientific article published in October 2012

Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

scientific article

Do short, frequent DNA sequence motifs mould the epigenome?

article

Does DNA methylation control transposition of selfish elements in the germline?

scientific article published in December 1997

Domains of methylated CAC and CG target MeCP2 to tune transcription in the brain

Dosage compensation in birds.

scientific article published in February 2001

Effects of DNA methylation on DNA-binding proteins and gene expression.

scientific article

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

scientific journal article

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

scientific article

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

scientific article

Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes

scientific article published in October 2016

Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis

scientific article

Female-specific hyperacetylation of histone H4 in the chicken Z chromosome.

scientific article published in January 2005

Functions for DNA Methylation in Vertebrates

scientific article published on 01 January 1993

Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome

scientific journal article

Gene expression: DNA methylation — how important in gene control?

scientific article published in Nature

Gene number in an invertebrate chordate, Ciona intestinalis

scientific article

Gene number, noise reduction and biological complexity

scientific article published on March 1995

Gene silencing by methyl-CpG-binding proteins.

scientific article published in January 1998

Gene silencing quantitatively controls the function of a developmental trans-activator

scientific article published on July 2002

Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome.

scientific article published on August 1994

Genetic determinants of the epigenome in development and cancer

scientific article published on 17 October 2017

Genome Biology: Not Drowning but Waving

scientific article published on 01 August 2013

Genomic Approaches Reveal Unexpected Genetic Divergence Within Ciona intestinalis

scientific article (publication date: 4 October 2005)

Genomic DNA methylation: the mark and its mediators

scientific article

Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes

scientific article

High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines.

scientific article

Histone deacetylases: silencers for hire.

scientific article

Identical sets of methylated and nonmethylated genes in Ciona intestinalis sperm and muscle cells.

scientific article

Identification and characterization of a family of mammalian methyl-CpG binding proteins

scientific article

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

scientific article

Il2 transcription unleashed by active DNA demethylation.

scientific article

Immortalization of conditionally transformed chicken cells: loss of normal p53 expression is an early step that is independent of cell transformation.

scientific article published on May 1992

Imprints on islands

scientific article published on 01 May 1993

Initiation of DNA replication at CpG islands in mammalian chromosomes

scientific article published on April 1998

Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome

scientific article

Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation

scientific article

Is Gene Amplification RNA-directed?

article

Isolation of CpG islands from large genomic clones

scientific article published in May 1999

Kaiso-deficient mice show resistance to intestinal cancer

scientific article

Light microscope autoradiography of ribosomal DNA amplification in Xenopus laevis

scientific article published on January 1974

Long-range restriction site mapping of mammalian genomic DNA.

scientific article published on July 1986

Loss of rDNA methylation accompanies the onset of ribosomal gene activity in early development of X. laevis

scientific article published on 01 November 1981

MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers.

scientific article

MBD2 deficiency does not accelerate p53 mediated lymphomagenesis

scientific article

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

scientific article (publication date: September 1999)

MBD2 is required for correct spatial gene expression in the gut.

scientific article published on 12 March 2007

MBD2-mediated transcriptional repression of the p14ARF tumor suppressor gene in human colon cancer cells

scientific article published on 15 October 2008

MBD4 deficiency does not increase mutation or accelerate tumorigenesis in mice lacking MMR.

scientific article

MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine

scientific journal article

MMDiff: quantitative testing for shape changes in ChIP-Seq data sets

scientific article

MOLECULAR BIOLOGY:DNA Methylation de Novo

scientific article published on 01 December 1999

Mammalian methyltransferases and methyl-CpG-binding domains: proteins involved in DNA methylation

scientific article

Mathematical modelling reveals how MeCP2 restrains transcriptional elongation in human neurons

Max Birnstiel 1933-2014: Gene pioneer

scientific article

Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains

scientific article

Mbd2 contributes to DNA methylation-directed repression of the Xist gene

scientific article published on 12 March 2007

Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.

scientific article published on 30 March 2018

MeCP2 and other methyl-CpG binding proteins

scientific article

MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex

scientific article published on 18 August 2004

MeCP2 binding to DNA depends upon hydration at methyl-CpG

scientific article

MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation

scientific article published in 2024

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

scientific journal article

MeCP2 mutations: progress towards understanding and treating Rett syndrome

scientific article published on 17 February 2017

MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain.

scientific article

Methylated and unmethylated DNA compartments in the sea urchin genome

scientific article published on 01 August 1979

Methylated and unmethylated ribosomal RNA genes in the mouse

article

Methylation analysis on individual chromosomes: improved protocol for bisulphite genomic sequencing.

scientific article published on February 1994

Methylation of genomes and genes at the invertebrate-vertebrate boundary

scientific article published on March 1997

Methylation of the genes for 18S, 28S, and 5S ribosomal RNA.

scientific article published on January 1984

Methylation-induced repression--belts, braces, and chromatin

scientific article (publication date: 24 November 1999)

Molecular biology. MeCP2 repression goes nonglobal

scientific article

Molecular biology. Methylation talk between histones and DNA.

scientific article published in December 2001

Molecular hybridization of 3H-labelled ribosomal RNA with DNA in ultrathin sections prepared for electron microscopy

scientific article published in 1971

Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome

scientific article

Mosaic methylation of the repeat unit of the human ribosomal RNA genes.

scientific article published on March 1997

Mutant weed breaks silence

scientific article published in Nature

Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

scientific article

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.

scientific article published on May 2000

Non-methylated CpG-rich islands at the human alpha-globin locus: implications for evolution of the alpha-globin pseudogene

scientific article published on April 1987

Non-methylated islands in fish genomes are GC-poor

scientific article published on April 1991

Nonmethylated transposable elements and methylated genes in a chordate genome

scientific article published in February 1999

Number of CpG islands and genes in human and mouse

scientific article published on December 1993

On the track of DNA methylation: an interview with Adrian Bird by Jane Gitschier

scientific article

Orphan CpG islands identify numerous conserved promoters in the mammalian genome

scientific article (publication date: 23 September 2010)

Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

scientific article

Perceptions of epigenetics

scientific article (publication date: 24 May 2007)

Predicting the total number of human genes

article

Purification of CpG islands using a methylated DNA binding column

scientific article (publication date: March 1994)

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

scientific article

Putting the DNA back into DNA methylation ⬇️

scientific article published on October 27, 2011

Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing

scientific article published on 13 October 2020

Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing

scientific article published on 26 May 2020

Quantitative regulation

R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes

article

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.

scientific article published on 11 October 2017

Reading the DNA methylation signal

scientific article

Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome

scientific article published on 10 December 2012

Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein

scientific article

Restriction endonuclease NciI is not blocked by CpG methylation

scientific article published on November 1993

Rett Syndrome: Crossing the Threshold to Clinical Translation

scientific article

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

scientific journal article

Rett syndrome: a complex disorder with simple roots

scientific article

Reversal of neurological defects in a mouse model of Rett syndrome

scientific article (publication date: 23 February 2007)

Reversibility of functional deficits in experimental models of Rett syndrome.

scientific article published on April 2010

Ribosomal RNA gene amplification by rolling circles

scientific article published in August 1974

Role of MBD2 in gene regulation and tumorigenesis

scientific article

Sequence analysis of transposable elements in the sea squirt, Ciona intestinalis.

scientific article published on November 2000

Sequence-specific DNA binding by AT-hook motifs in MeCP2.

scientific article published on 27 July 2016

Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency.

scientific article published in December 1999

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

scientific article published on October 1994

Specific protection of methylated CpGs in mammalian nuclei

scientific article published in August 1989

Structure and expression of the chicken retinoblastoma gene.

scientific article published in February 1994

Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders

scientific article

Studies of DNA methylation in animals

scientific article published on January 1995

Studies of the relationship between DNA methylation and transcription of the ribosomal RNA genes

article

Synthetic CpG islands reveal DNA sequence determinants of chromatin structure

scientific article published in 2014

Systemic delivery of MeCP2 rescues behavioral and cellular deficits in female mouse models of Rett syndrome

scientific article

Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells

scientific article

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.

scientific article published on September 2006

The Dinucleotide CG as a Genomic Signalling Module ⬇️

scientific article published on 03 February 2011

The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System

scientific article

The biological functions of the methyl-CpG-binding protein MeCP2 and its implication in Rett syndrome.

scientific article

The chromosomal distribution of CpG islands in the mouse: evidence for genome scrambling in the rodent lineage

scientific article published on March 1997

The dinucleotide CG as a genomic signalling module

The effect of interspecific oocytes on demethylation of sperm DNA.

scholarly article

The essentials of DNA methylation

scientific article

The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model

scientific article

The major form of MeCP2 has a novel N-terminus generated by alternative splicing

scientific journal article

The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse.

scientific article published in February 1996

The methyl-CpG-binding protein MeCP2 and neurological disease

scientific article

The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

scientific article published on 9 November 2002

The methylated component of the Neurospora crassa genome

scientific article

The molecular basis of differentiation and competence

The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

scientific article published on 8 December 2015

The origin of the rRNA precursor from Xenopus borealis, analysed in vivo and in vitro

scientific article published on December 1983

The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

scientific article

The relationship between protein synthesis and ribosomal DNA amplification in Xenopus laevis

scientific article published on 01 September 1971

The relationship of DNA methylation to cancer.

scientific article

The role of MeCP2 in the brain.

scientific article published on 29 June 2011

The solution structure of the domain from MeCP2 that binds to methylated DNA

scientific article

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

scientific article (publication date: 16 September 1999)

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

article

Transcription in oocytes of highly methylated rDNA from Xenopus laevis sperm.

scientific article published in November 1983

Transcriptional noise and the evolution of gene number

article

Transcriptional repression by methylation of CpG.

scientific article

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

scientific article

Two classes of observed frequency for rare-cutter sites in CpG islands

scientific article published on November 1989

Unmethylated CpG islands associated with genes in higher plant DNA.

scientific article published on August 1988

Unmethylated domains in vertebrate DNA.

scientific article

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome

scientific article

Use of restriction endonucleases to detect and isolate genes from mammalian cells

scientific article published on January 1992

Use of restriction enzymes to detect potential gene sequences in mammalian DNA.

scientific article

Use of restriction enzymes to study eukaryotic DNA methylation

Use of restriction enzymes to study eukaryotic DNA methylation: I. The methylation pattern in ribosomal DNA from Xenopus laevis

scientific article

Use of restriction enzymes to study eukaryotic DNA methylation: II. The symmetry of methylated sites supports semi-conservative copying of the methylation pattern.

scientific article

Variable patterns of total DNA and rDNA methylation in animals.

scientific article published on April 1980

Vestiges of a DNA methylation system in Drosophila melanogaster?

scientific article published in December 1999

dSIR2 and dHDAC6: two novel, inhibitor-resistant deacetylases in Drosophila melanogaster

scientific article

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