Search filters

List of works by Fredrik Bäckhed

23, 22 Calling the Microbiota to Control Atherosclerosis

scientific article published on 01 November 2018

99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: the normal gut microbiota in health and disease

scientific article published in April 2010

A catalog of the mouse gut metagenome

scientific article published on 28 September 2015

A role for the gut microbiota in energy harvesting?

scientific article published on 12 October 2010

Aberrant intestinal microbiota in individuals with prediabetes.

scientific article published on 29 January 2018

Abundance of gut Prevotella at baseline and metabolic response to barley prebiotics

scientific article published on 25 July 2018

Age-Dependent Susceptibility to Enteropathogenic Escherichia coli (EPEC) Infection in Mice

scientific article (publication date: May 2016)

Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility

scientific article

Alpha-haemolysin of uropathogenic E. coli induces Ca2+ oscillations in renal epithelial cells

scientific article published on June 2000

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

scientific article

Altered mucus glycosylation in core 1 O-glycan-deficient mice affects microbiota composition and intestinal architecture.

scientific article published on 09 January 2014

An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.

scientific article

Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88.

scientific article

Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism

scientific article published on 23 July 2009

Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism.

scientific article published in February 2012

Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice

scientific article published on 22 August 2016

Assessing the human gut microbiota in metabolic diseases

scientific article

Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

scientific article published on 21 December 2020

Bacterial profile in human atherosclerotic plaques.

scientific article published on 8 June 2017

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

scientific article published on 16 December 2017

Changes in intestinal microflora in obesity: cause or consequence?

scientific article published on 01 April 2009

Comparative analysis of human gut microbiota by barcoded pyrosequencing

scientific article

Coordinated regulation of the metabolome and lipidome at the host-microbial interface

scientific article

Could gut microbiota protect against sclerosing cholangitis?

scientific article published on 27 August 2015

Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor Signalling

scientific article

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

scientific article

Cyp3a11 is not essential for the formation of murine bile acids

scientific article published on 8 March 2017

Defining a healthy human gut microbiome: current concepts, future directions, and clinical applications

scientific article

Deletion of the gene encoding MyD88 protects from anorexia in a mouse tumor model

scientific article published on 18 January 2010

Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography

article

Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric bypass

scientific article published on 19 May 2017

Diet-microbiota interactions as moderators of human metabolism

scientific article

Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella

scientific article published on 6 November 2015

Dietary destabilisation of the balance between the microbiota and the colonic mucus barrier

scientific article published on 25 September 2018

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects.

scientific article published on 25 May 2018

Drug the Bug!

scientific article published on 01 December 2015

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

scientific article published on May 2015

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

scientific article published on 10 June 2015

Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism

scientific article published on October 2010

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

scholarly article

Effects of the gut microbiota on obesity and glucose homeostasis

scientific article published on 23 February 2011

Enterotypes in the landscape of gut microbial community composition.

scientific article published on 18 December 2017

Evolution, human-microbe interactions, and life history plasticity

scientific article

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development.

scientific article published on 13 April 2018

Expression of the blood-group-related glycosyltransferase B4galnt2 influences the intestinal microbiota in mice

scientific article

FXR is a molecular target for the effects of vertical sleeve gastrectomy

scientific article (publication date: 8 May 2014)

Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells

scientific article

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

scientific article

Functional interactions between the gut microbiota and host metabolism

scientific article (publication date: 13 September 2012)

Gastric mucosal recognition of Helicobacter pylori is independent of Toll-like receptor 4

scientific article published on 24 February 2003

Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice

article

Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

scientific article published on 06 April 2015

Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

scientific article published in March 2018

Gut metagenome in European women with normal, impaired and diabetic glucose control

scientific article

Gut microbial metabolites as multi-kingdom intermediates

scientific article published on 23 September 2020

Gut microbiota affects lens and retinal lipid composition.

scientific article published on 8 July 2009

Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling

scientific article published on 31 July 2018

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

scientific article

Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks.

scientific article published on 4 June 2018

Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice

scientific article published on 25 April 2012

Helicobacter pylori infection induces interleukin-8 receptor expression in the human gastric epithelium

scientific article

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

scientific article published on 5 May 2016

Host remodeling of the gut microbiome and metabolic changes during pregnancy

scientific article

Host responses to the human microbiome ⬇️

scientific article published on August 1, 2012

Host-bacterial mutualism in the human intestine

scientific article (publication date: 25 March 2005)

Host-microbiota interaction induces bi-phasic inflammation and glucose intolerance in mice

scientific article published on 21 September 2017

Human oral, gut, and plaque microbiota in patients with atherosclerosis

scientific article

Identification of target tissue glycosphingolipid receptors for uropathogenic, F1C-fimbriated Escherichia coli and its role in mucosal inflammation

scientific article published on 4 March 2002

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

scientific article published on 18 November 2020

Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe-/- Mice

scientific article published on 01 October 2018

In vitro co-cultures of human gut bacterial species as predicted from co-occurrence network analysis.

scientific article published on 30 March 2018

Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota

scientific article

Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract

scientific article published on March 2001

Infection regulates pro-resolving mediators that lower antibiotic requirements

scientific article published on 25 April 2012

Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells

scientific article published on 8 February 2013

Insights into the role of the microbiome in obesity and type 2 diabetes

scientific article published on January 2015

Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production

scientific article published on 25 January 2016

Integration of molecular profiles in a longitudinal wellness profiling cohort

scientific article published on 08 September 2020

Interaction between dietary lipids and gut microbiota regulates hepatic cholesterol metabolism

scientific article published on 18 January 2016

Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model

scientific article published on 05 November 2018

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

scientific article published on 15 June 2016

Intestinal Ralstonia pickettii augments glucose intolerance in obesity

scientific article

Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status

scientific article

Intestinal microbiota during infancy and its implications for obesity

scientific article published on March 2009

Intestinal permeability is associated with visceral adiposity in healthy women

scientific article published on 18 August 2011

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

scientific article

Know your neighbor: Microbiota and host epithelial cells interact locally to control intestinal function and physiology.

scientific article

Lactobacillus reuteri prevents diet-induced obesity, but not atherosclerosis, in a strain dependent fashion in Apoe-/- mice

scientific article

Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo-controlled, double-blind, clinical trial

scientific article published on 22 July 2018

Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers

scholarly article

Linking Microbiota to Human Diseases: A Systems Biology Perspective

scientific article published on 6 November 2015

Meat-metabolizing bacteria in atherosclerosis ⬇️

scientific article published on May 1, 2013

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

scientific article

Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled trial.

scientific article published on 23 December 2016

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

scientific article

Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity

scientific article published on 18 December 2018

Microbial modulation of energy availability in the colon regulates intestinal transit

scientific article published on November 2013

Microbial modulation of insulin sensitivity

scientific article

Microbial regulation of GLP-1 and L-cell biology

scientific article

Microbial regulation of SAA3 expression in mouse colon and adipose tissue

scientific article published on January 2010

Microbial regulation of the L cell transcriptome

scientific article published on 19 January 2018

Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus

scientific article

Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1

scientific article published on 25 October 2018

Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice

scientific article published on 22 June 2016

Microbiome and metabolome features of the cardiometabolic disease spectrum

scientific article published on 17 February 2022

Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity

scientific article

Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis

scientific article published in July 2016

Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits

scientific article published on 9 January 2014

Microbiota-induced obesity requires farnesoid X receptor

scientific article published on 6 January 2016

Nanoscale features influence epithelial cell morphology and cytokine production

article

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition

scientific article published in Nature

Network analyses identify liver-specific targets for treating liver diseases

scientific article published on 21 August 2017

Neurotensin Is Coexpressed, Coreleased, and Acts Together With GLP-1 and PYY in Enteroendocrine Control of Metabolism

scientific article published on 15 October 2015

Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization

scientific article published on 27 October 2015

Obesity alters gut microbial ecology

scientific article

Oral microbiota in patients with atherosclerosis

scientific article published on 24 October 2015

Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice.

scientific article

Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance

scientific article published on 27 February 2017

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.

scientific article published on 16 December 2016

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

scientific article published on 13 April 2009

Plasma Imidazole Propionate Is Positively Correlated with Blood Pressure in Overweight and Obese Humans

Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor

scholarly article

Programming of Host Metabolism by the Gut Microbiota ⬇️

scientific article published on August 12, 2011

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism

scientific article published on 01 February 2022

Protein Intake, Metabolic Status and the Gut Microbiota in Different Ethnicities: Results from Two Independent Cohorts

Publisher Correction: Enterotypes in the landscape of gut microbial community composition

scientific article published on 13 February 2018

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.

scientific article

Reduced obesity, diabetes and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier.

scientific article

Regulation of body fat mass by the gut microbiota: Possible mediation by the brain

scientific article published on 28 April 2015

Regulation of bone mass by the gut microbiota is dependent on NOD1 and NOD2 signaling

scientific article

Regulation of serum amyloid A3 (SAA3) in mouse colonic epithelium and adipose tissue by the intestinal microbiota

scientific article

Role of gut microbiota in atherosclerosis

scientific article published on December 2016

Role of the lipopolysaccharide-CD14 complex for the activity of hemolysin from uropathogenic Escherichia coli

scientific article published on 13 November 2006

Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission

scientific article published on 6 May 2015

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation.

scientific article

Shining light on microbial signaling to distant organs

scientific article published on 29 March 2019

Signals from the gut microbiota to distant organs in physiology and disease

scientific article

Simplified Intestinal Microbiota to Study Microbe-Diet-Host Interactions in a Mouse Model

article by Petia Kovatcheva-Datchary et al published 26 March 2019 in Cell Reports

Site-specific programming of the host epithelial transcriptome by the gut microbiota

scientific article published on 28 March 2015

Specific synbiotics in early life protect against diet-induced obesity in adult mice.

scientific article published on 20 February 2018

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

scientific article published on 06 May 2020

Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production

scientific article published on 01 March 2021

Structural requirements for TLR4-mediated LPS signalling: a biological role for LPS modifications

scientific article published on October 2003

Symptomatic atherosclerosis is associated with an altered gut metagenome

scientific article

TLR4-dependent lipopolysaccharide signalling in epithelial cells is independent of extracellular protease activity

scientific article published in May 2002

TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14.

scientific article

TRIF signaling drives homeostatic intestinal epithelial antimicrobial peptide expression

scientific article published on 10 September 2014

Targeting gut microbiota in obesity: effects of prebiotics and probiotics

scientific article published on 09 August 2011

The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos

scientific article published on 3 February 2016

The Gut Microbiota Reduces Colonization of the Mesenteric Lymph Nodes and IL-12-Independent IFN-γ Production During Salmonella Infection

scientific article published on 22 December 2015

The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

scientific article published on 01 June 2018

The composition of the gut microbiota shapes the colon mucus barrier.

scientific article

The endocannabinoid system links gut microbiota to adipogenesis

scientific article

The gut microbiota and metabolic disease: current understanding and future perspectives

scientific article

The gut microbiota and mucosal homeostasis: colonized at birth or at adulthood, does it matter?

scientific article published on 18 January 2013

The gut microbiota as an environmental factor that regulates fat storage

scientific article (publication date: 2 November 2004)

The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation

scientific article published on 5 October 2016

The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium

scientific article

The gut microbiota modulates glycaemic control and serum metabolite profiles in non-obese diabetic mice

scientific article

The gut microbiota modulates host amino acid and glutathione metabolism in mice

scientific article published on 16 October 2015

The gut microbiota modulates host energy and lipid metabolism in mice

scientific article

The gut microbiota reduces leptin sensitivity and the expression of the obesity-suppressing neuropeptides proglucagon (Gcg) and brain-derived neurotrophic factor (Bdnf) in the central nervous system

scientific article published on 26 July 2013

The gut microbiota regulates bone mass in mice

scientific article

The gut microbiota — masters of host development and physiology ⬇️

scientific article published on February 25, 2013

The human intestinal microbiota and its relationship to energy balance

The short-chain fatty acid receptor, FFA2, contributes to gestational glucose homeostasis

scientific article published on 22 September 2015

Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling

scientific article published on 11 March 2012

Toll-like receptor 4-mediated signaling by epithelial surfaces: necessity or threat?

scientific article

Paulina is supported by:

About Paulina

Help