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List of works by Frank J. Slack

A 'pivotal' new rule for microRNA-mRNA interactions.

scientific article published on 5 March 2012

A 3'-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysis

scientific article

A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk

scientific article

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

scientific article

A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer

scientific article

A developmental timing microRNA and its target regulate life span in C. elegans

scientific article

A developmental timing switch promotes axon outgrowth independent of known guidance receptors

scientific article (publication date: August 2010)

A novel mechanism of LIN-28 regulation of let-7 microRNA expression revealed by in vivo HITS-CLIP in C. elegans

scientific article published on 24 March 2015

A novel repeat domain that is often associated with RING finger and B-box motifs.

scientific article

A truth serum for cancer--microRNAs have major potential as cancer biomarkers

scientific article published in October 2008

ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity

scientific article published on 10 March 2020

Aberrant regulation and function of microRNAs in cancer.

scientific article

Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans

scientific article

Ageing and the small, non-coding RNA world.

scientific article

An elegant miRror: microRNAs in stem cells, developmental timing and cancer

scientific article published on 3 April 2009

Analysis of microRNA expression and function

scientific article

And now introducing mammalian mirtrons

scientific article published in November 2007

Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans

scientific article published in July 2013

Architecture of a validated microRNA::target interaction

scientific article published in December 2004

Arresting the Culprit: Targeted Antagomir Delivery to Sequester Oncogenic miR-221 in HCC

scientific article published on 20 March 2012

Association between KRAS rs61764370 and triple-negative breast cancer—a false positive? – Authors' reply

scientific article published on 01 August 2011

Autoregulation of lin-4 microRNA transcription by RNA activation (RNAa) in C. elegans

scientific article

Biases and errors on allele frequency estimation and disease association tests of next-generation sequencing of pooled samples

scientific article

Big roles for small RNAs

scientific article published in Nature

Cigarette-Smoke-Induced Dysregulation of MicroRNA Expression and Its Role in Lung Carcinogenesis.

scientific article published on December 2011

Cis-acting elements in its 3' UTR mediate post-transcriptional regulation of KRAS.

scientific article published on 22 February 2016

Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation.

scientific article

Comparative analysis of the transcriptome across distant species

scientific article

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

scientific article (publication date: 2 November 2000)

Developmental biomarkers of aging in Caenorhabditis elegans

scientific article published on May 2010

Developmental timing in C. elegans is regulated by kin-20 and tim-1, homologs of core circadian clock genes

scientific article

Discovery of Novel microRNAs in Aging Caenorhabditis elegans

scientific article published in January 2015

Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia

scientific article published on 01 March 2021

Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development

scientific article

Epstein-Barr virus-encoded EBNA2 alters immune checkpoint PD-L1 expression by downregulating miR-34a in B-cell lymphomas

scientific article published on 26 June 2018

Estrogen withdrawal, increased breast cancer risk and the KRAS-variant.

scientific article

Expression and function of members of a divergent nuclear receptor family in Caenorhabditis elegans

scientific article published in November 1999

Expression inactivation of SMARCA4 by microRNAs in lung tumors

scientific article

Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases

scientific article published on 03 February 2014

Identification of Bacillus subtilis adaptive response genes by subtractive differential hybridization ⬇️

scientific article published on September 1, 1991

Identification of specific let-7 microRNA binding complexes in Caenorhabditis elegans

scientific article

In this issue of Epigenetics: special focus on non-coding RNAs in epigenetic regulation

scientific article published on January 2014

Inhibiting microRNA function in vivo

scientific article published on 01 January 2009

Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells

scientific article

Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project

scientific article

Joint analysis of expression profiles from multiple cancers improves the identification of microRNA-gene interactions.

scientific article published on 14 June 2013

Junk DNA and the long non-coding RNA twist in cancer genetics.

scientific article

KRAS alleles: the LCS6 3'UTR variant and KRAS coding sequence mutations in the NCI-60 panel

scientific article

KRAS rs61764370 in Epithelial Ovarian Cancer-Letter

scientific article published on 01 October 2011

Malicious exosomes

scientific article published in Science

MiR-33 connects cholesterol to the cell cycle

scientific article published on 15 March 2012

Micro-RNAs: small is plentiful

scientific article

MicroRNA in cancer prognosis

scientific article

MicroRNA predictors of longevity in Caenorhabditis elegans

scientific article (publication date: September 2011)

MicroRNA signatures differentiate melanoma subtypes

scientific article

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.

scientific article

MicroRNA therapeutics in preclinical cancer models.

scientific article published in April 2011

MicroRNA-mediated regulation of KRAS in cancer

scientific article

MicroRNAs Regulate Expression of Oncogenes ⬇️

scientific article published on April 23, 2012

MicroRNAs and cancer: a meeting summary of the eponymous Keystone Conference

scientific article published on 11 February 2010

MicroRNAs and the genetic network in aging.

scientific article published on 23 January 2013

MicroRNAs and their roles in aging.

scientific article published on January 2012

MicroRNAs as a potential magic bullet in cancer.

scientific article

MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy

scientific article

MicroRNAs as potential cancer therapeutics.

scientific article

MicroRNAs both promote and antagonize longevity in C. elegans.

scientific article

MicroRNAs circulate around Alzheimer's disease

scientific article published on 29 July 2013

MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy ⬇️

scientific article published on November 24, 2011

MicroRNAs in search of a target.

scientific article published on January 2006

MicroRNAs in the ionizing radiation response and in radiotherapy

scientific article published on 28 February 2013

MicroRNAs mediate dietary-restriction-induced longevity through PHA-4/FOXA and SKN-1/Nrf transcription factors

scientific article

MicroRNAs micromanage themselves

scientific article published on November 2012

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

scientific article

Noncoding RNAs and Cancer

scientific article published on 01 March 2013

Novel microRNAs differentially expressed during aging in the mouse brain

scientific article (publication date: 2012)

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.

scientific article

Oncomirs - microRNAs with a role in cancer

scientific article (publication date: April 2006)

Prediction and characterization of noncoding RNAs in C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data

scientific article

Prevention of K-Ras- and Pten-mediated intravaginal tumors by treatment with camptothecin-loaded PLGA nanoparticles.

scientific article

Quantitative analysis of microRNAs in tissue microarrays by in situ hybridization.

scientific article

Quantitative and multiplex microRNA assays from unprocessed cells in isolated nanoliter well arrays

scholarly article by Augusto M Tentori et al published 7 August 2018 in Lab on a Chip

RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans

scientific article

RAS is regulated by the let-7 microRNA family

scientific article (publication date: 11 March 2005)

RNA-mediated gene activation

scientific article

Rare BRCA1 haplotypes including 3'UTR SNPs associated with breast cancer risk

scientific article

Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis

scientific article

Regulatory RNAs and the demise of 'junk' DNA.

scientific article published on January 2006

Retraction to “A 3′ UTR KRAS variant as a biomarker of poor outcome and chemotherapy resistance in ovarian cancer” [Gynecol. Oncol. 120 (2011) S3] ⬇️

scientific article published on 01 July 2011

Ribosomal protein RPS-14 modulates let-7 microRNA function in Caenorhabditis elegans

scientific article

Robust and specific inhibition of microRNAs in Caenorhabditis elegans

scientific article published on April 2010

Severe COVID-19 is associated with molecular signatures of aging in the human brain

scientific article published in 2022

Small RNAs deliver a blow to ovarian cancer

scientific article

Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice

scientific article

TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs

scientific article published on 20 August 2020

Targeted resequencing of the microRNAome and 3'UTRome reveals functional germline DNA variants with altered prevalence in epithelial ovarian cancer.

scientific article

Targetome profiling, pathway analysis and genetic association study implicate miR-202 in lymphomagenesis

scientific article published on 18 January 2013

Temporal and spatial patterning of an organ by a single transcription factor

scientific article

Temporal pattern formation by heterochronic genes

scientific article published on January 1997

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

scientific article (publication date: 24 February 2000)

The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target.

scientific article published in May 2003

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

scientific article

The Caenorhabditis elegans pumilio homolog, puf-9, is required for the 3'UTR-mediated repression of the let-7 microRNA target gene, hbl-1

scientific article

The Duality of OncomiR Addiction in the Maintenance and Treatment of Cancer ⬇️

scientific article published on May 1, 2012

The Inescapable Influence of Noncoding RNAs in Cancer

scientific article published on 13 November 2015

The POU transcription factor UNC-86 controls the timing and ventral guidance of Caenorhabditis elegans axon growth

scientific article published on 8 June 2011

The evolution of animal microRNA function.

scientific article published on 20 February 2007

The expression of the Alzheimer's amyloid precursor protein-like gene is regulated by developmental timing microRNAs and their targets in Caenorhabditis elegans

scientific article published on 8 January 2008

The let-7 microRNA represses cell proliferation pathways in human cells

scientific article (publication date: 15 August 2007)

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer

scientific article published on 21 December 2021

The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

scientific article

The multiple roles of microRNA-155 in oncogenesis

scientific article published on 28 September 2013

The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition

scientific article published on 2 June 2010

The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans

scientific article (publication date: March 2005)

The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter

scientific article (publication date: 15 July 2003)

The tumor-suppressive and potential therapeutic functions of miR-34a in epithelial carcinomas.

scientific article published on 11 December 2015

Transcription of the C. elegans let-7 microRNA is temporally regulated by one of its targets, hbl-1

scientific article

acn-1, a C. elegans homologue of ACE, genetically interacts with the let-7 microRNA and other heterochronic genes

scientific article

kin-19/casein kinase Iα has dual functions in regulating asymmetric division and terminal differentiation in C. elegans epidermal stem cells

scientific article

let-7 microRNAs in development, stem cells and cancer

scientific article

lin-4 and the NRDE pathway are required to activate a transgenic lin-4 reporter but not the endogenous lin-4 locus in C. elegans.

scientific article

miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction

scientific article

miR-155 drives oncogenesis by promoting and cooperating with mutations in the c-Kit oncogene

scientific article published on 20 November 2018

miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage

scientific article published on 21 March 2016

miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer.

scientific article published on 16 December 2015

miRNA modulation of the cellular stress response

scientific article published on April 2008

miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma.

scientific article

microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis

scientific article published on 30 June 2009

microRNAs: small molecules with big roles - C. elegans to human cancer

scientific article published on February 2008

siRNA. A guide for RNA silencing

scientific article published in October 2002

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