List of works - Geir Bjørkøy

A reporter cell system to monitor autophagy based on p62/SQSTM1.

scientific article published on 28 August 2010

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

scientific article

Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia

scientific article published on 21 August 2019

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis

scientific article

Autophagy turns specific: the discovery of p62 and NBR1 as autophagy cargo receptors

scientific article

Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

scientific article

Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy

scientific article published on 19 April 2009

DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy

scientific article published on 13 November 2015

Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization

scientific article

Detection of mRNA transcripts of truncated opiate precursor (POMC) in human cartilage

scientific article published in May 2006

Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction

scientific article published on 25 August 2014

Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.

scientific article published on September 1995

Expression of functional mu-opioid receptors in human osteoarthritic cartilage and chondrocytes

scientific article

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport

scientific article

Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells

scientific article (publication date: 21 January 2017)

Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells

scientific article published on 23 September 2016

Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity

scientific article published on 24 April 2014

Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

scientific article (publication date: 5 September 2003)

Intracellular and surface distribution of monocyte tissue factor: application to intersubject variability

scientific article

Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells

scientific article published on 15 July 2016

MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity.

scientific article

Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer

scientific article published on 28 February 2013

Monitoring autophagic degradation of p62/SQSTM1.

scientific article published in January 2009

N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2.

scientific article published on 18 August 2017

NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype

scientific article published on January 1994

Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda

scientific article

Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies.

scientific article published on 15 December 2009

Oncogenes--"reckless drivers" on signal pathways controlling cell division

scientific article published on May 10, 1998

Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations.

scientific article

Radiation-induced upregulation of gamma-glutamyltransferase in colon carcinoma cells is mediated through the Ras signal transduction pathway

scientific article published on 9 December 2005

Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer

scientific article published on 24 April 2015

Reversion of Ras- and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of protein kinase C lambda is accompanied by the loss of constitutive nuclear mitogen-activated protein k

scientific article published on April 1997

Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor

scientific article published on 31 January 2014

Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines

scientific article published on 15 October 2011

The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells

scientific article

The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions

scientific article

Transforming growth factor-β-inducible early response gene 1 is a novel substrate for atypical protein kinase Cs.

scientific article

Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers

scientific article published on 22 June 2016

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

scientific article

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

scientific article

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

scientific article (publication date: 21 November 2005)

p62/SQSTM1: a missing link between protein aggregates and the autophagy machinery

scientific article published on 14 April 2006

List of works by Geir Bjørkøy

A reporter cell system to monitor autophagy based on p62/SQSTM1.

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis

Autophagy turns specific: the discovery of p62 and NBR1 as autophagy cargo receptors

Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling

Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy

DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy

Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization

Detection of mRNA transcripts of truncated opiate precursor (POMC) in human cartilage

Endocytosis of secreted carboxyl ester lipase in a syndrome of diabetes and pancreatic exocrine dysfunction

Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.

Expression of functional mu-opioid receptors in human osteoarthritic cartilage and chondrocytes

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport

Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells

Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells

Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity

Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

Intracellular and surface distribution of monocyte tissue factor: application to intersubject variability

Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells

MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity.

Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer

Monitoring autophagic degradation of p62/SQSTM1.

N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2.

NIH 3T3 cells stably transfected with the gene encoding phosphatidylcholine-hydrolyzing phospholipase C from Bacillus cereus acquire a transformed phenotype

Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda

Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies.

Oncogenes--"reckless drivers" on signal pathways controlling cell division

Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations.

Radiation-induced upregulation of gamma-glutamyltransferase in colon carcinoma cells is mediated through the Ras signal transduction pathway

Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer

Reversion of Ras- and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of protein kinase C lambda is accompanied by the loss of constitutive nuclear mitogen-activated protein k

Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor

Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines

The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells

The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions

Transforming growth factor-β-inducible early response gene 1 is a novel substrate for atypical protein kinase Cs.

Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

p62/SQSTM1: a missing link between protein aggregates and the autophagy machinery