List of works - Martin Noble

Active and inactive protein kinases: structural basis for regulation

scientific article (publication date: 19 April 1996)

Presenting your structures: the CCP4mg molecular-graphics software

scientific article (publication date: April 2011)

Protein kinase inhibitors: insights into drug design from structure.

scientific article published on March 2004

Developments in the CCP4 molecular-graphics project

scientific article (publication date: December 2004)

A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain

scientific article

The structural basis for control of eukaryotic protein kinases

scientific article published on 05 April 2012

The CCP4 molecular-graphics project

scientific article (publication date: November 2002)

Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3

scientific article

The Eleventh Datta Lecture. The structural basis for substrate recognition and control by protein kinases

scientific article published in June 1998

Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction

scientific article

Generation of protein lattices by fusing proteins with matching rotational symmetry

scientific article

The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate

scientific article

Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.

scientific article published in February 2004

The structural basis of localization and signaling by the focal adhesion targeting domain

scientific article

Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product

scientific article

The cyclin box fold: protein recognition in cell-cycle and transcription control

scientific article published on December 1997

Cyclin-dependent kinases: inhibition and substrate recognition.

scientific article

Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A

scientific article

Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

scientific article

Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4

scientific article

Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain

scientific article published on September 2005

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

scientific article

Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate

scientific article published in May 2001

Molecular recognition of paxillin LD motifs by the focal adhesion targeting domain

scientific article

How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A.

scientific article published on 9 November 2006

CCP4i2: the new graphical user interface to the CCP4 program suite.

scientific article published in February 2018

Structures of the Dsk2 UBL and UBA domains and their complex

scientific article

Dynamite: a simple way to gain insight into protein motions

scientific article published on 26 November 2004

The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases

scientific article

Recent developments in cyclin-dependent kinase biochemical and structural studies.

scientific article published on 12 October 2009

Comparison of the refined crystal structures of liganded and unliganded chicken, yeast and trypanosomal triosephosphate isomerase

scientific article published on April 1992

Catalytic mechanism of phosphorylase kinase probed by mutational studies

scientific article

Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects

scientific article published in January 2003

Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency

scientific article published on 11 February 2011

The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition

scientific article

Structures of P. falciparum PfPK5 test the CDK regulation paradigm and suggest mechanisms of small molecule inhibition

scientific article

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12

scientific article

N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2

scientific article

Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase

scientific article

Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant

scientific article published on 01 February 1993

Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase

scientific journal article

CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.

scientific article published on 13 April 2015

Structure-based design of cyclin-dependent kinase inhibitors

scientific article

Purification, characterization, and crystallization of an N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium

scientific article published in April 1998

Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines

scientific article published on August 2005

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis.

scientific article published in March 2005

Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives

scientific article

Arylamine N-acetyltransferases in mycobacteria

scientific article published on July 2008

Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure–Activity Relationship, and Anticancer Activities

scientific article

Molecular motions of human cyclin-dependent kinase 2.

scientific article published on 28 January 2005

List of works by Martin Noble

Active and inactive protein kinases: structural basis for regulation

Presenting your structures: the CCP4mg molecular-graphics software

Protein kinase inhibitors: insights into drug design from structure.

Developments in the CCP4 molecular-graphics project

A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain

The structural basis for control of eukaryotic protein kinases

The CCP4 molecular-graphics project

Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3

The Eleventh Datta Lecture. The structural basis for substrate recognition and control by protein kinases

Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction

Generation of protein lattices by fusing proteins with matching rotational symmetry

The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate

Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.

The structural basis of localization and signaling by the focal adhesion targeting domain

Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product

The cyclin box fold: protein recognition in cell-cycle and transcription control

Cyclin-dependent kinases: inhibition and substrate recognition.

Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A

Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4

Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate

Molecular recognition of paxillin LD motifs by the focal adhesion targeting domain

How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A.

CCP4i2: the new graphical user interface to the CCP4 program suite.

Structures of the Dsk2 UBL and UBA domains and their complex

Dynamite: a simple way to gain insight into protein motions

The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases

Recent developments in cyclin-dependent kinase biochemical and structural studies.

Comparison of the refined crystal structures of liganded and unliganded chicken, yeast and trypanosomal triosephosphate isomerase

Catalytic mechanism of phosphorylase kinase probed by mutational studies

Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects

Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency

The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition

Structures of P. falciparum PfPK5 test the CDK regulation paradigm and suggest mechanisms of small molecule inhibition

Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12

N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2

Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase

Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant

Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase

CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.

Structure-based design of cyclin-dependent kinase inhibitors

Purification, characterization, and crystallization of an N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium

Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis.

Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives

Arylamine N-acetyltransferases in mycobacteria

Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure–Activity Relationship, and Anticancer Activities

Molecular motions of human cyclin-dependent kinase 2.