List of works - Thomas C. Terwilliger

PHENIX: a comprehensive Python-based system for macromolecular structure solution

scientific article

PHENIX: building new software for automated crystallographic structure determination

scientific article (publication date: November 2002)

Towards automated crystallographic structure refinement with phenix.refine

scientific article (publication date: April 2012)

Engineering and characterization of a superfolder green fluorescent protein

scientific article

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard

scientific article (publication date: 2008)

Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard

scientific article (publication date: June 2009)

The Phenix software for automated determination of macromolecular structures

scientific article (publication date: September 2011)

Protein production and purification

scientific article

Improved molecular replacement by density- and energy-guided protein structure optimization

scientific article (publication date: 26 May 2011)

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

scientific article published on 02 October 2019

Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli

scientific article

New tools for the analysis and validation of cryo-EM maps and atomic models

scientific article published on 03 September 2018

Improved low-resolution crystallographic refinement with Phenix and Rosetta

scientific article

Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias

scientific article published on 19 April 2008

phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta

scientific article

FEM: feature-enhanced map.

scientific article

Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 A resolution

scientific article

Graphical tools for macromolecular crystallography in PHENIX

scientific article

Advances, interactions, and future developments in the CNS, Phenix, and Rosetta structural biology software systems

scientific article published on 28 February 2013

A new protein-protein interaction sensor based on tripartite split-GFP association

scientific article

Lessons from structural genomics

scientific article (publication date: 2009)

Domain Orientation in the Inactive Response Regulator Mycobacterium tuberculosis MtrA Provides a Barrier to Activation † , ‡

scientific article

Automated ligand fitting by core-fragment fitting and extension into density

scientific article published on 18 July 2006

Interpretation of ensembles created by multiple iterative rebuilding of macromolecular models

scientific article published on 21 April 2007

Ligand identification using electron-density map correlations

scientific article published on 13 December 2006

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop

scientific article

Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT

scientific article

Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis

scientific journal article

A fully automatic method yielding initial models from high-resolution cryo-electron microscopy maps

scientific article published on 30 October 2018

New molecular reporters for rapid protein folding assays

scientific article

Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering

scientific article

The TB Structural Genomics Consortium: a decade of progress

scientific article published on 17 January 2011

Solution structure of Rv2377c-founding member of the MbtH-like protein family

scientific article

Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum

scientific article

Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement

scientific article

MAD phasing: Bayesian estimates of F(A).

scientific article published in January 1994

Continuous mutual improvement of macromolecular structure models in the PDB and of X-ray crystallographic software: the dual role of deposited experimental data

scientific article

Automated, high-throughput platform for protein solubility screening using a split-GFP system

scientific article

Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution

scientific article

Macromolecular X-ray structure determination using weak, single-wavelength anomalous data

scientific article

Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing.

scientific article published on March 2016

Rapid model building of α-helices in electron-density maps

scientific article published on February 12, 2010

Automating crystallographic structure solution and refinement of protein-ligand complexes.

scientific article published on 25 December 2013

Automated identification of elemental ions in macromolecular crystal structures

scientific article published on 20 March 2014

The success of structural genomics

scientific article published on June 17, 2011

The optimization of in vitro high-throughput chemical lysis of Escherichia coli. Application to ACP domain of the polyketide synthase ppsC from Mycobacterium tuberculosis

scientific article

Model morphing and sequence assignment after molecular replacement

scientific article published on 18 October 2013

Recent developments in phasing and structure refinement for macromolecular crystallography

scientific article published on 21 August 2009

Experimental mapping of soluble protein domains using a hierarchical approach

scientific article

Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal.

scientific article

List of works by Thomas C. Terwilliger

PHENIX: a comprehensive Python-based system for macromolecular structure solution

PHENIX: building new software for automated crystallographic structure determination

Towards automated crystallographic structure refinement with phenix.refine

Engineering and characterization of a superfolder green fluorescent protein

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard

Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard

The Phenix software for automated determination of macromolecular structures

Protein production and purification

Improved molecular replacement by density- and energy-guided protein structure optimization

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli

New tools for the analysis and validation of cryo-EM maps and atomic models

Improved low-resolution crystallographic refinement with Phenix and Rosetta

Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias

phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta

FEM: feature-enhanced map.

Structure of translation initiation factor 5A from Pyrobaculum aerophilum at 1.75 A resolution

Graphical tools for macromolecular crystallography in PHENIX

Advances, interactions, and future developments in the CNS, Phenix, and Rosetta structural biology software systems

A new protein-protein interaction sensor based on tripartite split-GFP association

Lessons from structural genomics

Domain Orientation in the Inactive Response Regulator Mycobacterium tuberculosis MtrA Provides a Barrier to Activation † , ‡

Automated ligand fitting by core-fragment fitting and extension into density

Interpretation of ensembles created by multiple iterative rebuilding of macromolecular models

Ligand identification using electron-density map correlations

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop

Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT

Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis

A fully automatic method yielding initial models from high-resolution cryo-electron microscopy maps

New molecular reporters for rapid protein folding assays

Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering

The TB Structural Genomics Consortium: a decade of progress

Solution structure of Rv2377c-founding member of the MbtH-like protein family

Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum

Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement

MAD phasing: Bayesian estimates of F(A).

Continuous mutual improvement of macromolecular structure models in the PDB and of X-ray crystallographic software: the dual role of deposited experimental data

Automated, high-throughput platform for protein solubility screening using a split-GFP system

Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution

Macromolecular X-ray structure determination using weak, single-wavelength anomalous data

Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing.

Rapid model building of α-helices in electron-density maps

Automating crystallographic structure solution and refinement of protein-ligand complexes.

Automated identification of elemental ions in macromolecular crystal structures

The success of structural genomics

The optimization of in vitro high-throughput chemical lysis of Escherichia coli. Application to ACP domain of the polyketide synthase ppsC from Mycobacterium tuberculosis

Model morphing and sequence assignment after molecular replacement

Recent developments in phasing and structure refinement for macromolecular crystallography

Experimental mapping of soluble protein domains using a hierarchical approach

Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal.