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List of works by Erik J. Sontheimer

"siRNAs and miRNAs": a meeting report on RNA silencing.

scientific article

A Cas9 with PAM recognition for adenine dinucleotides

scientific article published on 18 May 2020

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

scientific article published in April 2004

A fork in the road for microRNAs.

scientific article published in August 2007

A role for ubiquitin in the spliceosome assembly pathway

scientific article published on 20 April 2008

A split prime editor with untethered reverse transcriptase and circular RNA template

scientific article published in 2022

ATP modulates siRNA interactions with an endogenous human Dicer complex

scientific article published on 21 September 2005

Accelerating expansion.

scientific article published in April 2015

Adapting dCas9-APEX2 for subnuclear proteomic profiling

scientific article published on 10 December 2018

All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo

scientific article published on 19 September 2018

An engineered ScCas9 with broad PAM range and high specificity and activity

scientific article published on 11 May 2020

An inside job for siRNAs

scientific article

Assembly and function of RNA silencing complexes

scientific article

Autoantibodies against a serine tRNA-protein complex implicated in cotranslational selenocysteine insertion ⬇️

scientific article published on October 15, 1992

Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis.

scientific article

CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA

scientific article (publication date: 19 December 2008)

CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea

scientific article (publication date: March 2010)

CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease

scientific article published on 26 November 2021

CRISPRs from scratch

scientific article published in March 2018

DNase H Activity of Neisseria meningitidis Cas9.

scientific article

Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

scientific article (publication date: 2 April 2004)

Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.

scientific article published on 6 July 2018

Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice

scientific article published on 09 April 2021

Inhibition of CRISPR-Cas systems by mobile genetic elements

scientific article published on 29 June 2017

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.

scientific article published on 26 June 2019

Invasive DNA, chopped and in the CRISPR.

scientific article published in June 2009

Kinetic characterization of the second step of group II intron splicing: role of metal ions and the cleavage site 2'-OH in catalysis

scientific article published on October 2000

Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae

scientific article published on 26 April 2012

Metal ion catalysis during splicing of premessenger RNA

scientific article published in Nature

Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns

scientific article published on February 2000

Microbiology: slicer for DNA.

scientific article published on November 2010

Molecular biology. Argonaute journeys into the heart of RISC.

scientific article published on September 2004

Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway.

scientific article published on 22 September 2005

Origins and Mechanisms of miRNAs and siRNAs

scientific article (publication date: 20 February 2009)

Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing

scientific article published in Nature Communications

Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins

scientific article published on 04 December 2018

Primary processing of CRISPR RNA by the endonuclease Cas6 in Staphylococcus epidermidis.

scientific article

Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis

scientific article published on May 2013

Proteomics identification of Drosophila small interfering RNA-associated factors.

scientific article

Publisher Correction: An engineered ScCas9 with broad PAM range and high specificity and activity

scientific article published on 19 June 2020

Publisher Correction: Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing

scientific article published in Nature Communications

Quit stalling or you'll be silenced

scientific article published in February 2013

R2D2 leads the silencing trigger to mRNA's death star

scientific article published in October 2003

RNAi: RISC gets loaded.

scientific article published in November 2005

SPO24 is a transcriptionally dynamic, small ORF-encoding locus required for efficient sporulation in Saccharomyces cerevisiae.

scientific article

Self versus non-self discrimination during CRISPR RNA-directed immunity.

scientific article

Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo

scientific article published on 01 November 2021

Separation of Drosophila RNA silencing complexes by native gel electrophoresis.

scientific article published in January 2005

Silence from within: endogenous siRNAs and miRNAs.

scientific article

Small RNAs of Opposite Sign… but Same Absolute Value

scientific article published on 01 December 2012

Structural biology. Cascading into focus.

scientific article

The Bacterial Origins of the CRISPR Genome-Editing Revolution

scientific article

The Making of an siRNA.

scientific article

The spliceosome shows its metal

scientific article published on 01 January 2001

Thermodynamic and structural characterization of 2'-nitrogen-modified RNA duplexes.

scientific article published on 28 June 2004

Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins

scientific article published on 22 August 2019

Type II-C CRISPR-Cas9 Biology, Mechanism, and Application

scientific article published on 4 December 2017

Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p

scientific article

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