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List of works by Michael Lund Nielsen

A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast ⬇️

scientific article

A dual pressure linear ion trap Orbitrap instrument with very high sequencing speed.

scientific article published on 14 October 2009

A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

scientific article

A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles

scientific article (publication date: October 2011)

A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates

scientific article published in 2024

ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines

scientific article published in 2024

ATP enhances neuronal differentiation of PC12 cells by activating PKCα interactions with cytoskeletal proteins.

scientific article

Advances in characterizing ubiquitylation sites by mass spectrometry.

scientific article published on 05 January 2013

Advantages of External Accumulation for Electron Capture Dissociation in Fourier Transform Mass Spectrometry

scientific article published on 01 July 2001

An Advanced Strategy for Comprehensive Profiling of ADP-ribosylation Sites Using Mass Spectrometry-based Proteomics

scientific article published on 23 February 2019

An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

scientific article

Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID).

scientific article published on 3 June 2014

Analytical utility of small neutral losses from reduced species in electron capture dissociation studied using SwedECD database.

scientific article published on 7 October 2008

Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl.

scientific article published in April 2018

Backbone carbonyl group basicities are related to gas-phase fragmentation of peptides and protein folding.

scientific article

Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

scientific article

Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

scientific article published on 12 June 2017

CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

scientific article published on 14 June 2013

Can relative cleavage frequencies in peptides provide additional sequence information?

Citrullination of HP1γ chromodomain affects association with chromatin

scientific article published on 02 April 2019

Citrullination regulates pluripotency and histone H1 binding to chromatin

scientific journal article

Complementary sequence preferences of electron-capture dissociation and vibrational excitation in fragmentation of polypeptide polycations.

scientific article

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

scientific article published on 28 September 2008

Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes

scientific article (publication date: July 2012)

DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network

scientific article published on 14 April 2021

De novo peptide sequencing and identification with precision mass spectrometry

scientific article published on January 2007

Electrospray Ionization Tandem Mass Spectrometry Sequencing of Novel Skin Peptides from Ranid Frogs Containing Disulfide Bridges

scientific article published on 01 January 2007

Experiences and perspectives of MALDI MS and MS/MS in proteomic research

Extent of Modifications in Human Proteome Samples and Their Effect on Dynamic Range of Analysis in Shotgun Proteomics

scientific article published on 02 October 2006

Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

scientific article

Hydrogen rearrangement to and from radical z fragments in electron capture dissociation of peptides.

scientific article published on 23 October 2006

HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain

scientific article published on 10 November 2003

Identification of dominant signaling pathways from proteomics expression data.

scientific article

Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation.

scientific article

Improved Reversed Phase Chromatography of Hydrophilic Peptides from Spatial and Temporal Changes in Column Temperature.

scientific article

Improving protein identification using complementary fragmentation techniques in fourier transform mass spectrometry

scientific article

Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism

scientific article published on 01 May 2018

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

scientific article published on 09 May 2019

Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

scientific article published in June 2008

Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing

scientific article

Large-Scale Identification of the Arginine Methylome by Mass Spectrometry

scientific article published on 2 November 2015

Liquid chromatography at critical conditions: comprehensive approach to sequence-dependent retention time prediction.

scientific article published in November 2006

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).

scientific article

Lysine acetylation targets protein complexes and co-regulates major cellular functions

scientific article (publication date: 14 August 2009)

ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures.

scientific article published on 25 January 2006

Multi-site SUMOylation restrains DNA polymerase η interactions with DNA damage sites

scientific article published on 29 April 2020

On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein

scientific article

Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer

scientific article

PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination

scientific article published on 01 April 2019

Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation

scientific article (publication date: 2012)

Physicochemical Properties Determining the Detection Probability of Tryptic Peptides in Fourier Transform Mass Spectrometry. A Correlation Study

scientific article published on 01 October 2004

Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography-Tandem Mass Spectrometry

scientific article published on January 2017

Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

scientific article (publication date: 30 August 2016)

Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses

scientific article published on 19 September 2013

Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue.

scientific article published on 30 September 2016

Proteomic Analysis of Arginine Methylation Sites in Human Cells Reveals Dynamic Regulation During Transcriptional Arrest

scientific article (publication date: 21 February 2014)

Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues

scientific article published on 11 July 2012

Proteomics-grade de novo sequencing approach

scientific article published in 2005

Relative specificities of water and ammonia losses from backbone fragments in collision-activated dissociation.

scientific article published on 16 May 2007

SUMOylation promotes protective responses to DNA-protein crosslinks

article

Serine-linked PARP1 auto-modification controls PARP inhibitor response

scientific article published on 01 July 2021

Shifted-basis technique improves accuracy of peak position determination in Fourier transform mass spectrometry.

scientific article published in April 2004

Side-Chain Losses in Electron Capture Dissociation To Improve Peptide Identification

scientific article published on 03 February 2007

Site-specific characterization of endogenous SUMOylation across species and organs.

scientific article published on 25 June 2018

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

scientific article published on 23 January 2017

Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation

scientific article published on 14 October 2021

Specificity and Commonality of the Phosphoinositide-Binding Proteome Analyzed by Quantitative Mass Spectrometry

scientific article published on 23 January 2014

Specifying RNA-Binding Regions in Proteins by Peptide Cross-Linking and Affinity Purification

scientific article

SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides

scientific article published on 21 August 2007

Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation

scientific article published on 01 August 2018

Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

scientific article

Tandem MALDI/EI ionization for tandem Fourier transform ion cyclotron resonance mass spectrometry of polypeptides

The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage

scientific article published on 27 July 2014

The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

scientific article

The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels

scientific article

The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator

scientific article

The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

scientific article published on 08 October 2021

Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication.

scientific article published on 06 March 2014

Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

scientific article published on 08 January 2020

Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

scientific article published on 20 May 2021

Using Guanidine-Hydrochloride for Fast and Efficient Protein Digestion and Single-step Affinity-purification Mass Spectrometry

scientific article published on 26 December 2012

VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

scientific article published in 2024

Waves of sumoylation support transcription dynamics during adipocyte differentiation

scientific article published on 01 February 2022

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