List of works - David Vetrie

A Complete YAC Contig and Cosmid Interval Map Covering the Entirety of Human Xq21.33 to Xq22.3 from DXS3 to DXS287

scientific article published on 01 July 1997

A novel X-linked gene, DDP, shows mutations in families with deafness (DFN-1), dystonia, mental deficiency and blindness

scientific article

Applications of genomic microarrays to explore human chromosome structure and function.

scientific article published in October 2004

Autosomal-dominant microtia linked to five tandem copies of a copy-number-variable region at chromosome 4p16

scientific article

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

scientific article

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.

scientific article published on 28 October 2016

Cancer: Repositioned to kill stem cells.

scientific article

Characterization of DRP2, a novel human dystrophin homologue

scientific journal article

Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL.

scientific article published on 7 November 2013

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution

scientific article

Construction of a yeast artificial chromosome contig encompassing the human alpha 5(IV) collagen gene (COL4A5).

scientific article

DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones

scientific article published on April 2003

DNA rearrangements in the α5(IV) collagen gene (COL4A5) of individuals with alport syndrome: Further refinement using pulsed-field gel electrophoresis

article

Detection of mutations in COL4A5 in patients with Alport Syndrome

article

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells

scientific article

Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition

scientific article published on 14 September 2016

Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms and therapeutic options.

scientific article published in August 2017

Exon array CGH: detection of copy-number changes at the resolution of individual exons in the human genome

scientific article

Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome

scientific article

From genomes to vaccines: Leishmania as a model

scientific article

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

scientific article published on 28 April 2009

Gene expression profiling in polycythemia vera using cDNA microarray technology.

scientific article

Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology

article

Genetic aspects of renal dysfunction: Alport's syndrome

scientific article published on 01 September 1994

Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus

scientific article

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

scientific article published in June 2007

Identification of Btk mutations in 20 unrelated patients with X-Iinked agammaglobulinaemia (XLA)

article

Identification of deletions in the btk gene allows unambiguous assessment of carrier status in families with X-linked agammaglobulinaemia.

scientific article

Identification of genetic aberrations on chromosome 22 outside the NF2 locus in schwannomatosis and neurofibromatosis type 2.

scientific article

Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites

scientific article

Isolation of cDNA clones mapping around DXS178: a search for human X-linked agammaglobulinaemia gene using yeast artificial chromosomes, cosmids and direct cDNA selection.

scientific article published on January 1993

Isolation of cosmid and cDNA clones in the region surrounding the BTK gene at Xq21.3-q22

scientific article (publication date: June 1994)

Long-range mapping of the gene for the human alpha 5(IV) collagen chain at Xq22-q23.

scientific article published on January 1992

Major rearrangements in the α5(IV) collagen gene in three patients with alport syndrome

article

Molecular diagnosis of X-linked agammaglobulinaemia

scientific article published in The Lancet

Pelizaeus-Merzbacher disease: identification of Xq22 proteolipid-protein duplications and characterization of breakpoints by interphase FISH.

scientific article

Physical mapping shows close linkage between the alpha-galactosidase A gene (GLA) and the DXS178 locus.

scientific article published on August 1993

Position effect on PLP1 may cause a subset of Pelizaeus-Merzbacher disease symptoms

scientific article published in December 2004

Requirement of bic/microRNA-155 for normal immune function

scientific article

Somatic mosaicism associated with a mild Alport syndrome phenotype

scientific article published on March 2000

Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase disease

scientific article

The chronic myeloid leukemia stem cell: stemming the tide of persistence

scientific article published on 3 February 2017

The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993.

scientific article published in April 2012

The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins

scientific article

The implications of the cloning of the XLA gene.

scientific article

The landscape of histone modifications across 1% of the human genome in five human cell lines

scientific article

The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML

scientific article published on 06 January 2020

Tyrosine kinase inhibitor independent gene expression signature in CML offers new targets for LSPC eradication therapy

Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data

scientific article

X inactivation as a mechanism of selection against lethal alleles: further investigation of incontinentia pigmenti and X linked lymphoproliferative disease ⬇️

scientific article published on September 1, 1992

X inactivation patterns in females with Alport's syndrome: a means of selecting against a deleterious gene?

scientific article

List of works by David Vetrie

A Complete YAC Contig and Cosmid Interval Map Covering the Entirety of Human Xq21.33 to Xq22.3 from DXS3 to DXS287

A novel X-linked gene, DDP, shows mutations in families with deafness (DFN-1), dystonia, mental deficiency and blindness

Applications of genomic microarrays to explore human chromosome structure and function.

Autosomal-dominant microtia linked to five tandem copies of a copy-number-variable region at chromosome 4p16

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.

Cancer: Repositioned to kill stem cells.

Characterization of DRP2, a novel human dystrophin homologue

Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL.

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution

Construction of a yeast artificial chromosome contig encompassing the human alpha 5(IV) collagen gene (COL4A5).

DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones

DNA rearrangements in the α5(IV) collagen gene (COL4A5) of individuals with alport syndrome: Further refinement using pulsed-field gel electrophoresis

Detection of mutations in COL4A5 in patients with Alport Syndrome

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells

Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition

Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms and therapeutic options.

Exon array CGH: detection of copy-number changes at the resolution of individual exons in the human genome

Expression profiling of the Leishmania life cycle: cDNA arrays identify developmentally regulated genes present but not annotated in the genome

From genomes to vaccines: Leishmania as a model

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

Gene expression profiling in polycythemia vera using cDNA microarray technology.

Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology

Genetic aspects of renal dysfunction: Alport's syndrome

Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Identification of Btk mutations in 20 unrelated patients with X-Iinked agammaglobulinaemia (XLA)

Identification of deletions in the btk gene allows unambiguous assessment of carrier status in families with X-linked agammaglobulinaemia.

Identification of genetic aberrations on chromosome 22 outside the NF2 locus in schwannomatosis and neurofibromatosis type 2.

Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites

Isolation of cDNA clones mapping around DXS178: a search for human X-linked agammaglobulinaemia gene using yeast artificial chromosomes, cosmids and direct cDNA selection.

Isolation of cosmid and cDNA clones in the region surrounding the BTK gene at Xq21.3-q22

Long-range mapping of the gene for the human alpha 5(IV) collagen chain at Xq22-q23.

Major rearrangements in the α5(IV) collagen gene in three patients with alport syndrome

Molecular diagnosis of X-linked agammaglobulinaemia

Pelizaeus-Merzbacher disease: identification of Xq22 proteolipid-protein duplications and characterization of breakpoints by interphase FISH.

Physical mapping shows close linkage between the alpha-galactosidase A gene (GLA) and the DXS178 locus.

Position effect on PLP1 may cause a subset of Pelizaeus-Merzbacher disease symptoms

Requirement of bic/microRNA-155 for normal immune function

Somatic mosaicism associated with a mild Alport syndrome phenotype

Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase disease

The chronic myeloid leukemia stem cell: stemming the tide of persistence

The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993.

The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins

The implications of the cloning of the XLA gene.

The landscape of histone modifications across 1% of the human genome in five human cell lines

The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML

Tyrosine kinase inhibitor independent gene expression signature in CML offers new targets for LSPC eradication therapy

Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data

X inactivation as a mechanism of selection against lethal alleles: further investigation of incontinentia pigmenti and X linked lymphoproliferative disease ⬇️

X inactivation patterns in females with Alport's syndrome: a means of selecting against a deleterious gene?