List of works - Andrew A Hicks

2q37 as a susceptibility locus for idiopathic basal ganglia calcification (IBGC) in a large South Tyrolean family

scientific article

32-channel time-correlated-single-photon-counting system for high-throughput lifetime imaging.

scientific article published on August 2017

52 Genetic Loci Influencing Myocardial Mass

scientific article

A Gene Map of the Human Genome

scientific article

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

scientific article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A common inversion under selection in Europeans

scientific article (publication date: February 2005)

A genetic risk factor for periodic limb movements in sleep

scientific article

A genome wide linkage disequilibrium screen in Parkinson’s disease

scientific article published on 23 February 2005

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project

scientific article

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.

scientific article

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

scientific article

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

scientific article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A susceptibility gene for late-onset idiopathic Parkinson's disease

article

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction

scientific article published on 10 November 2005

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Brain structure and task-specific increase in expression of the gene encoding syntaxin 1B during learning in the rat: a potential molecular marker for learning-induced synaptic plasticity in neural networks

scientific article published in October 1996

Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates

scientific article

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis

scientific article published on 24 October 2008

Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to distal 5q by linkage analysis

scientific article

Copy number variation across European populations

scientific article

Copy number variation and association over T-cell receptor genes--influence of DNA source

scientific article published on 26 June 2010

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article published on 30 March 2015

Corrigendum: SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila.

scientific article published in April 2019

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology

scientific article published on 17 February 2022

Dinucleotide repeat polymorphism in the human X-linked GABAA receptor alpha 3-subunit gene

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and fine mapping of serum protein loci through transethnic meta-analysis

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Distinct regional expression of nicotinic acetylcholine receptor genes in chick brain

scientific article

Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

scientific article published on 18 November 2016

Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson's Disease Penetrance.

scientific article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Evaluation of the role of STAP1 in Familial Hypercholesterolemia

scientific article published on 19 August 2019

Evidence of inbreeding depression on human height

scientific article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Familial Aggregation of Parkinson's Disease in Iceland

scholarly article by Sigurlaug Sveinbjörnsdóttir et al published 14 December 2000 in The New England Journal of Medicine

Fine-mapping of restless legs locus 4 (RLS4) identifies a haplotype over the SPATS2L and KCTD18 genes

scientific article published on 2 October 2012

Further evidence for clustering of human GABAA receptor subunit genes: localization of the alpha 6-subunit gene (GABRA6) to distal chromosome 5q by linkage analysis.

scientific article

Generation of Induced Pluripotent Stem Cells from Frozen Buffy Coats using Non-integrating Episomal Plasmids

scientific article

Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture

scientific article published on 02 August 2021

Genes for the GABAA receptor subunit types and their expression

scientific article published on January 1, 1992

Genes predict village of origin in rural Europe

scientific article

Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids

scientific article published on 12 April 2012

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic architecture of circulating lipid levels

scientific article

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease

scientific article

Genetic determinants of circulating sphingolipid concentrations in European populations

scientific article published on 02 October 2009

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

scientific article

Genetic evidence of assortative mating in humans

article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in RBFOX3 are associated with sleep latency

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.

scientific article

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide analysis of epistasis in body mass index using multiple human populations

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster

scientific article

Genome-wide association analysis identifies multiple loci related to resting heart rate

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study identifies 48 common genetic variants associated with handedness

scientific article published on 28 September 2020

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

scientific article

Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts

scientific article (publication date: 2012)

Genome-wide linkage analysis of serum creatinine in three isolated European populations.

scientific article published on 22 April 2009

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Genomic mapping and evolution of human GABA A receptor subunit gene clusters

article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels

scientific article

Identification of a set of endogenous reference genes for miRNA expression studies in Parkinson's disease blood samples

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Importance of different types of prior knowledge in selecting genome-wide findings for follow-up

scientific article published on February 2013

Increase in syntaxin 1B and glutamate release in mossy fibre terminals following induction of LTP in the dentate gyrus: a candidate molecular mechanism underlying transsynaptic plasticity

scientific article published in July 1998

Induction of long-term potentiation in vivo regulates alternate splicing to alter syntaxin 3 isoform expression in rat dentate gyrus

scientific article published in August 1998

Informed consent in the genomics era

scientific article

Involvement of proprotein convertase PCSK7 in the regulation of systemic iron homeostasis

article published in 2013

Kinase inhibition of G2019S-LRRK2 enhances autolysosome formation and function to reduce endogenous alpha-synuclein intracellular inclusions

scientific article published on 08 June 2020

Large-scale assessment of polyglutamine repeat expansions in Parkinson disease

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

scientific article published on 10 April 2017

Large-scale replication and heterogeneity in Parkinson disease genetic loci

scientific article

Linkage and association analysis of hyperthyrotropinaemia in an Alpine population reveal two novel loci on chromosomes 3q28-29 and 6q26-27.

scientific article published on 20 June 2011

Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene

scientific article published on 22 October 2009

Localising loci underlying complex trait variation using Regional Genomic Relationship Mapping

scientific article

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

scientific article (publication date: 2009)

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels

scientific article

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels

scientific article

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

scientific article published on 30 March 2017

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

scientific article

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Overexpression of blood microRNAs 103a, 30b, and 29a in L-dopa-treated patients with PD.

scientific article published on 16 January 2015

PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain

scientific article

PLA2G6mutations and Parkinsonism: Long-term follow-up of clinical features and neuropathology

scholarly article by Christine Klein et al published 6 October 2016 in Movement Disorders

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

scientific article published in Nature Communications

ParkScreen: a low-cost rapid linkage marker panel for Parkinson's disease

scientific article published on 25 March 2009

Parkin Interacts with Apoptosis-Inducing Factor and Interferes with Its Translocation to the Nucleus in Neuronal Cells ⬇️

scientific article published on 11 February 2019

Parkingene modifies the effect ofRLS4on the age at onset of restless legs syndrome (RLS)

Plasma and White Blood Cells Show Different miRNA Expression Profiles in Parkinson's Disease

scientific article published on 24 May 2017

Plasmid-normalized quantification of relative mitochondrial DNA copy number

scientific article published in Scientific Reports

Pre-analytic evaluation of volumetric absorptive microsampling and integration in a mass spectrometry-based metabolomics workflow

scientific article published on 17 August 2017

Primary familial brain calcification in the 'IBGC2' kindred: All linkage roads lead to SLC20A2.

scientific article published on 27 September 2016

Profiling of Parkin-binding partners using tandem affinity purification

scientific article

Prospective epidemiological, molecular, and genetic characterization of a novel coronavirus disease in the Val Venosta/Vinschgau: the CHRIS COVID-19 study protocol

scientific article published on 12 October 2021

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Restless legs syndrome: an update on genetics and future perspectives

scientific article published on 06 December 2007

SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila

scientific article published on 3 April 2017

SLP-2: a potential new target for improving mitochondrial function in Parkinson's disease

scientific article published in September 2017

SNP prioritization using a Bayesian probability of association

scientific article published on 26 December 2012

Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits

scientific article published on 3 August 2011

Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Synapsin I and syntaxin 1B: key elements in the control of neurotransmitter release are regulated by neuronal activation and long-term potentiation in vivo

scientific article published in July 1997

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The Cooperative Health Research in South Tyrol (CHRIS) study: rationale, objectives, and preliminary results

scientific article

The Expression of Syntaxin1B/GR33 mRNA Is Enhanced in the Hippocampal Kindling Model of Epileptogenesis ⬇️

scientific article published on 01 November 1995

The Impact of CRISPR/Cas9 Technology on Cardiac Research: From Disease Modelling to Therapeutic Approaches

scientific article published on 25 December 2017

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism

scientific article published on November 2014

The chicken GABAA receptor alpha 1 subunit: cDNA sequence and localization of the corresponding mRNA.

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Transsynaptic expression of a presynaptic glutamate receptor during hippocampal long-term potentiation

scientific article

Update on the management of restless legs syndrome: existing and emerging treatment options

scientific article published on 8 September 2010

Variants in STAT5B Associate with Serum TC and LDL-C Levels

article published in 2011

Variation in the Uric Acid Transporter Gene SLC2A9 and Its Association with AAO of Parkinson’s Disease

article

List of works by Andrew A Hicks

2q37 as a susceptibility locus for idiopathic basal ganglia calcification (IBGC) in a large South Tyrolean family

32-channel time-correlated-single-photon-counting system for high-throughput lifetime imaging.

52 Genetic Loci Influencing Myocardial Mass

A Gene Map of the Human Genome

A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila

A catalog of genetic loci associated with kidney function from analyses of a million individuals

A common inversion under selection in Europeans

A genetic risk factor for periodic limb movements in sleep

A genome wide linkage disequilibrium screen in Parkinson’s disease

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project

A genome-wide association search for type 2 diabetes genes in African Americans

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

A susceptibility gene for late-onset idiopathic Parkinson's disease

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Associations of autozygosity with a broad range of human phenotypes

Biological, clinical and population relevance of 95 loci for blood lipids

Brain structure and task-specific increase in expression of the gene encoding syntaxin 1B during learning in the rat: a potential molecular marker for learning-induced synaptic plasticity in neural networks

Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

Common variants associated with plasma triglycerides and risk for coronary artery disease

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis

Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to distal 5q by linkage analysis

Copy number variation across European populations

Copy number variation and association over T-cell receptor genes--influence of DNA source

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Corrigendum: SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila.

Defining the role of common variation in the genomic and biological architecture of adult human height

Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology

Dinucleotide repeat polymorphism in the human X-linked GABAA receptor alpha 3-subunit gene

Directional dominance on stature and cognition in diverse human populations

Discovery and fine mapping of serum protein loci through transethnic meta-analysis

Discovery and refinement of loci associated with lipid levels

Distinct regional expression of nicotinic acetylcholine receptor genes in chick brain

Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson's Disease Penetrance.

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Evaluation of the role of STAP1 in Familial Hypercholesterolemia

Evidence of inbreeding depression on human height

FTO genotype is associated with phenotypic variability of body mass index

Familial Aggregation of Parkinson's Disease in Iceland

Fine-mapping of restless legs locus 4 (RLS4) identifies a haplotype over the SPATS2L and KCTD18 genes

Further evidence for clustering of human GABAA receptor subunit genes: localization of the alpha 6-subunit gene (GABRA6) to distal chromosome 5q by linkage analysis.

Generation of Induced Pluripotent Stem Cells from Frozen Buffy Coats using Non-integrating Episomal Plasmids

Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture

Genes for the GABAA receptor subunit types and their expression

Genes predict village of origin in rural Europe

Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic architecture of circulating lipid levels

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease

Genetic determinants of circulating sphingolipid concentrations in European populations

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

Genetic evidence of assortative mating in humans

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants in RBFOX3 are associated with sleep latency

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Genome-wide analysis of epistasis in body mass index using multiple human populations

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster

Genome-wide association analysis identifies multiple loci related to resting heart rate

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study identifies 48 common genetic variants associated with handedness

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations