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List of works by Cristen J. Willer

A first stage genome-wide screen for regions shared identical-by-descent in hutterite families with multiple sclerosis

scientific article published on 01 June 2008

A genome scan for genes underlying adult body size differences between Central African hunter-gatherers and farmers

scientific article published on 14 July 2018

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide scan in forty large pedigrees with multiple sclerosis

scientific article published on 15 November 2007

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A reference panel of 64,976 haplotypes for genotype imputation

scientific article

Accurate local-ancestry inference in exome-sequenced admixed individuals via off-target sequence reads

scientific article

An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group

scientific article published on 6 April 2004

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association between microchimerism and multiple sclerosis in Canadian twins.

scientific article

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

scientific article

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

scientific article published on 14 January 2019

Author Correction: Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

scientific article published on 22 December 2020

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

scientific article published on 14 July 2020

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

scientific article published on 30 July 2018

Biological and clinical insights from genetics of insomnia symptoms

scientific article published on 25 February 2019

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Coding variants in and increase risk of atrial fibrillation

scientific article published on 12 June 2018

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article

Common variants in the GDF5-UQCC region are associated with variation in human height

scientific article

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals

scientific article

Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance

scientific article published on 01 June 2005

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

scientific article published on 27 July 2009

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

scientific article published in Nature Communications

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

scientific article published on 24 August 2020

Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations

scientific article

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

scientific article published on 13 August 2018

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis

scientific article published on 22 August 2001

Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

scientific article published on 30 October 2017

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

scientific article published on 21 October 2020

Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese

scientific article

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Exploring and visualizing large-scale genetic associations by using PheWeb

scientific article published on 01 June 2020

Finding genes and variants for lipid levels after genome-wide association analysis

scientific article published on April 2012

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

scientific article published on 07 August 2020

Genetic evidence of assortative mating in humans

article

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

scientific article published on 13 June 2018

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

scientific article published in 2022

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic susceptibility to MS: a second stage analysis in Canadian MS families

scientific article published on July 2001

Genetically determined height and coronary artery disease

scientific article

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

article

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

scientific article published on 27 December 2017

Genome-wide analysis yields new loci associating with aortic valve stenosis

scientific article published on 7 March 2018

Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes

scientific article published on 13 August 2019

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

scientific article published on 16 November 2020

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomic inflation factors under polygenic inheritance

scientific article

Genotype imputation

scientific article (publication date: 2009)

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels.

scientific article published on September 2017

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

LocusZoom: regional visualization of genome-wide association scan results

scientific article (publication date: 15 September 2010)

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

scientific article published on 18 June 2014

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

scientific article published on 23 October 2020

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

scientific article

Maternal - offspring HLA-DRB1 compatibility in multiple sclerosis

scientific article published on 01 July 2005

Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort

scientific article published on 26 October 2020

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of gene-level tests for rare variant association

scientific article published on 15 December 2013

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article

Microchimerism in autoimmunity and transplantation: potential relevance to multiple sclerosis

scientific article

Multiple sclerosis susceptibility and the X chromosome

scientific article published in August 2007

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

scientific article

No large-effect low-frequency coding variation found for myocardial infarction

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parent-of-origin effect in multiple sclerosis: observations in half-siblings

scientific article published in The Lancet

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

scientific article (publication date: 11 August 2012)

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

scientific article published on 15 May 2017

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations

scientific article

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations

Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts

scientific article published on 18 May 2020

Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes

scientific article published in January 2007

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

scientific article published on 23 April 2019

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

scientific article published on February 2017

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

scientific article

TCR beta polymorphisms and multiple sclerosis

scientific article published in August 2004

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The power of genetic diversity in genome-wide association studies of lipids

The power of meta-analysis in genome-wide association studies

scientific article (publication date: 2013)

Timing of birth and risk of multiple sclerosis: population based study

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Twin concordance and sibling recurrence rates in multiple sclerosis.

scientific article

Use of a Polygenic Risk Score Improves Prediction of Myocardial Injury after Non-cardiac Surgery

scientific article published on 09 June 2020

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

scientific article

Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.

scientific article

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

scientific article

WikiGWA: an open platform for collecting and using genome-wide association results

scientific article (publication date: April 2013)

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