List of works by Jordan Raff

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.

scientific article

A homeostatic clock sets daughter centriole size in flies.

scientific article published on 2 March 2018

A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies

scientific article published on 15 February 2017

A positive feedback loop drives centrosome maturation in flies

Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation

scientific article published on 22 July 2021

Ana3 is a conserved protein required for the structural integrity of centrioles and basal bodies

scientific article published on 26 October 2009

Asterless licenses daughter centrioles to duplicate for the first time in Drosophila embryos

scientific article published on 15 May 2014

Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules

scientific article published on September 2005

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

scientific article published on 19 September 2005

CP110 exhibits novel regulatory activities during centriole assembly in Drosophila

scientific article

Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly

scientific article published on 03 May 2022

Centrosome amplification can initiate tumorigenesis in flies.

scientific article published on June 2008

DSas-6 and Ana2 coassemble into tubules to promote centriole duplication and engagement

scientific article published on December 2010

Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes

scientific article published on 24 October 2013

Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC

scientific article

Different Drosophila cell types exhibit differences in mitotic centrosome assembly dynamics

scientific article published on August 2015

Dissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivo

scientific article (publication date: May 2015)

Drosophila Ana1 is required for centrosome assembly and centriole elongation ⬇️

scientific article published on 20 May 2016

Drosophila Ana2 is a conserved centriole duplication factor

scientific article

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

scientific article

Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation

scientific article published on 9 February 2018

Drosophila PLP forms centriolar-clouds that promote centriole stability, cohesion and MT nucleation

article published in 2017

Drosophila Spd-2 recruits PCM to the sperm centriole, but is dispensable for centriole duplication.

scientific article

Drosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults

scientific article published on 30 August 2016

Evidence that a positive feedback loop drives centrosome maturation in fly embryos

scientific article published on 09 September 2019

Happy 5th Birthday Biology Open

scientific article published on 15 July 2017

Hsp90 is required to localise cyclin B and Msps/ch-TOG to the mitotic spindle in Drosophila and humans.

scientific article

Lessons learned: eight years at the helm of Biology Open

article published in 2018

Maintaining the proper connection between the centrioles and the pericentriolar matrix requires Drosophila centrosomin

scientific article

Mitosis in motion

scientific article published in January 1996

Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.

scientific article published on 3 May 2007

Sas-6, Ana2 and Sas-4 self-organise into macromolecular structures that can be used to probe centriole/centrosome assembly

scientific article published on 14 May 2020

Structural Basis for Mitotic Centrosome Assembly in Flies

scientific article published on June 2017

The Drosophila GAGA transcription factor is associated with specific regions of heterochromatin throughout the cell cycle

scientific article published on December 1994

The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation.

scientific article

The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

scientific article

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies

scientific article published on 23 May 2015

The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time

scientific article published on 24 June 2002

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