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List of works by Oliver Rackham

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The human mitochondrial transcriptome

scientific article
Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs

scientific article
RNA processing in human mitochondria

scientific article
A network of orthogonal ribosome x mRNA pairs.

scientific article
Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

scientific article published on 25 October 2011
Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation

scientific article
Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomes

scientific article
A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.

scientific article published on 21 July 2007
Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.

scientific article published on 21 December 2010
Modular recognition of nucleic acids by PUF, TALE and PPR proteins

scientific article published on January 10, 2012
An artificial PPR scaffold for programmable RNA recognition

scientific article
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

scientific article published on 3 August 2016
Cellular logic with orthogonal ribosomes.

scientific article
The role of mammalian PPR domain proteins in the regulation of mitochondrial gene expression

scientific article published on 26 October 2011
Pentatricopeptide repeats: modular blocks for building RNA-binding proteins

scientific article published on 23 April 2013
MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins.

scientific article
Organelle transcriptomes: products of a deconstructed genome

scientific article published on 07 August 2013
Specialization from synthesis: How ribosome diversity can customize protein function

scientific article published on February 26, 2013
Designer RNA-binding proteins: New tools for manipulating the transcriptome

scientific article published on November 1, 2011
Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation

scientific article published on 27 December 2012
LRPPRC-mediated folding of the mitochondrial transcriptome

scientific article published on 16 November 2017
Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice

scientific article
Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

scientific article published on 31 October 2013
Transterm: a database of mRNAs and translational control elements.

scientific article published on January 2002
SLIRP stabilizes LRPPRC via an RRM-PPR protein interface

scientific article published on 28 June 2016
Building a Parallel Metabolism within the Cell

scientific article published on 4 January 2008
Transcriptome-wide effects of a POLR3A gene mutation in patients with an unusual phenotype of striatal involvement

scientific article published on 9 August 2016
Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM

scientific article published in Nature
Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction

scientific journal article
Estrogen-mediated regulation of mitochondrial gene expression.

scientific article
Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z

scientific article published on 20 August 2018
Adult-onset obesity is triggered by impaired mitochondrial gene expression.

scientific article published on 16 August 2017
A bifunctional protein regulates mitochondrial protein synthesis

scientific article (publication date: May 2014)
Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.

scientific article published on 23 March 2018
Simultaneous processing and degradation of mitochondrial RNAs revealed by circularized RNA sequencing

scientific article
Analysis of the Human Mitochondrial Transcriptome Using Directional Deep Sequencing and Parallel Analysis of RNA Ends

scientific article published on January 1, 2014
Synthesizing cellular networks from evolved ribosome-mRNA pairs

scientific article published in April 2006
Supernumerary proteins of mitochondrial ribosomes.

scientific article published on 17 August 2013
Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia

scientific article published on 4 October 2011
PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly.

scientific article published in April 2018
Mitochondria: Unusual features of the mammalian mitoribosome

scientific article published on 16 May 2014
Modulation of miRNA function by natural and synthetic RNA-binding proteins in cancer

scientific article published on 04 June 2019
CirGO: an alternative circular way of visualising gene ontology terms

article
Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction

scientific article published on 05 October 2018
Is mitochondrial gene expression coordinated or stochastic?

article
Regulation of a minimal transcriptome by repeat domain proteins.

scientific article published on 23 August 2017
Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.

scientific article published on 7 June 2018
Fidelity of translation initiation is required for coordinated respiratory complex assembly

scientific article published on 20 December 2019
Manipulating and elucidating mitochondrial gene expression with engineered proteins

scientific article published on 02 December 2019
A modified yeast three-hybrid system enabling both positive and negative selections

scientific article published on 18 May 2018

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