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List of works by Oliver Rackham

A bifunctional protein regulates mitochondrial protein synthesis

scientific article (publication date: May 2014)

A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance

scientific article published on 24 September 2021

A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria.

scientific article published on 21 July 2007

A modified yeast three-hybrid system enabling both positive and negative selections

scientific article published on 18 May 2018

A mutation in MT-TW causes a tRNA processing defect and reduced mitochondrial function in a family with Leigh syndrome.

scientific article published on 30 October 2015

A network of orthogonal ribosome x mRNA pairs.

scientific article

Adult-onset obesity is triggered by impaired mitochondrial gene expression.

scientific article published on 16 August 2017

An Artificial Yeast Genetic Circuit Enables Deep Mutational Scanning of an Antimicrobial Resistance Protein

scientific article published on 17 July 2018

An artificial PPR scaffold for programmable RNA recognition

scientific article

Analysis of the human mitochondrial transcriptome using directional deep sequencing and parallel analysis of RNA ends.

scientific article published in January 2014

Building a Parallel Metabolism within the Cell

scientific article published on 4 January 2008

Building artificial genetic circuits to understand protein function

scientific article published on 22 November 2019

Cellular logic with orthogonal ribosomes.

scientific article

CirGO: an alternative circular way of visualising gene ontology terms

article

Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z

scientific article published on 20 August 2018

Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomes

scientific article

Defects in RNA metabolism in mitochondrial disease.

scientific article published on 8 February 2017

Designer RNA-binding proteins: New tools for manipulating the transcriptome

scientific article

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

scientific article published on 03 October 2019

Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction

scientific article published on 05 October 2018

Engineered rRNA enhances the efficiency of selenocysteine incorporation during translation

scientific article published on 27 December 2012

Estrogen-mediated regulation of mitochondrial gene expression.

scientific article

Fidelity and coordination of mitochondrial protein synthesis in health and disease

scientific article published on 25 July 2020

Fidelity of translation initiation is required for coordinated respiratory complex assembly

scientific article published on 20 December 2019

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.

scientific article published on 3 August 2016

Is mitochondrial gene expression coordinated or stochastic?

article

LRPPRC-mediated folding of the mitochondrial transcriptome

scientific article published on 16 November 2017

Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins

scientific article published on 25 October 2011

Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice

scientific article

MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins.

scientific article

Manipulating and elucidating mitochondrial gene expression with engineered proteins

scientific article published on 02 December 2019

Mapping of mitochondrial RNA-protein interactions by digital RNase footprinting

scientific article published on 31 October 2013

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.

scientific article published on 23 March 2018

Mitochondria: Unusual features of the mammalian mitoribosome

scientific article published on 16 May 2014

Modular recognition of nucleic acids by PUF, TALE and PPR proteins

scientific article published on 10 January 2012

Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.

scientific article published on 7 June 2018

Modulation of miRNA function by natural and synthetic RNA-binding proteins in cancer

scientific article published on 04 June 2019

Molecular basis of translation termination at noncanonical stop codons in human mitochondria

scientific article published on 04 May 2023

Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction

scientific journal article

OmicsVolcano: Software for intuitive visualization and interactive exploration of high-throughput biological data

scientific article published on 22 January 2021

Organelle transcriptomes: products of a deconstructed genome

scientific article published on 07 August 2013

PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly.

scientific article published in April 2018

Pentatricopeptide repeats: modular blocks for building RNA-binding proteins

scientific article published on 23 April 2013

Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia

scientific article published on 4 October 2011

RNA processing in human mitochondria

scientific article

Regulation of a minimal transcriptome by repeat domain proteins.

scientific article published on 23 August 2017

SLIRP stabilizes LRPPRC via an RRM-PPR protein interface

scientific article published on 28 June 2016

Simultaneous processing and degradation of mitochondrial RNAs revealed by circularized RNA sequencing

scientific article

Specialization from synthesis: how ribosome diversity can customize protein function

scientific article published on 26 February 2013

Stepwise maturation of the peptidyl transferase region of human mitoribosomes

scientific article published on 16 June 2021

Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation

scientific article published on 13 November 2019

Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation

scientific article

Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.

scientific article published on 21 December 2010

Supernumerary proteins of mitochondrial ribosomes.

scientific article published on 17 August 2013

Synthesizing cellular networks from evolved ribosome-mRNA pairs

scientific article published in April 2006

The human mitochondrial transcriptome

scientific article

The role of mammalian PPR domain proteins in the regulation of mitochondrial gene expression

scientific article published on 26 October 2011

Tighter Ligand Binding Can Compensate for Impaired Stability of an RNA-Binding Protein

scientific article published on 29 May 2018

Transcriptome-wide effects of a POLR3A gene mutation in patients with an unusual phenotype of striatal involvement

scientific article published on 9 August 2016

Transterm: a database of mRNAs and translational control elements.

scientific article published on January 2002

Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM

scientific article published in Nature

Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs

scientific article

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