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List of works by Joachim Wittbrodt

11-P010 Zebrafish and medaka: Model organisms for a comparative developmental approach of brain asymmetry

4DXpress: a database for cross-species expression pattern comparisons

scientific article published on 04 October 2007

A Novel Mammal-Specific Three Partite Enhancer Element Regulates Node and Notochord-Specific Noto Expression ⬇️

scientific article published on October 22, 2012

A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing

scientific article published in July 2004

A global survey identifies novel upstream components of the Ath5 neurogenic network

scientific article published on 07 September 2009

A screen for co-factors of Six3.

scientific article published in September 2002

A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms

scientific article published in January 2006

A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes

scientific article published in July 2004

A trans-Regulatory Code for the Forebrain Expression of Six3.2 in the Medaka Fish

scientific article published on 16 September 2015

Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina

Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina.

scientific article published on 29 January 2018

An eye on eye development

scientific article published on 15 May 2013

An eye on light-sheet microscopy

scientific article

An inexpensive and versatile computer-controlled PCR machine using a Peltier Element as a thermoelectric heat pump

scientific article published in July 1989

Analysis of cellular behavior and cytoskeletal dynamics reveal a constriction mechanism driving optic cup morphogenesis

scientific article

Analysis of heterologous and homologous promoters and enhancers in vitro and in vivo by gene transfer into Japanese medaka (Oryzias latipes) Xiphophorus

article

Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences

scientific article (publication date: 2008)

ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation

scientific article published on 22 May 2013

Arthropod-like expression patterns of engrailed and wingless in the annelid Platynereis dumerilii suggest a role in segment formation.

scientific article published in October 2003

Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identification of a source for the physiological ligand

scientific article published on April 1994

Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions

scientific article published on 06 February 2020

Bifacial stem cell niches in fish and plants

scientific article published on 24 February 2017

Birth and life of tissue macrophages and their migration in embryogenesis and inflammation in medaka

scientific article published in January 2007

CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

scientific article published in 2015

Cavefish eye loss in response to an early block in retinal differentiation progression

scientific article published on 23 January 2015

Cell cycle control by homeobox genes in development and disease

scientific article

Characterization and developmentally regulated expression of four annexins in the killifish medaka.

scientific article

Characterization of teleost Mdga1 using a gene-trap approach in medaka (Oryzias latipes).

scientific article published in August 2009

Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

scientific article

Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain.

scientific article

Cis-regulatory properties of medaka synexpression groups

scientific article published on March 2012

Cloning and expression of medaka Dachshund

scientific article published in March 2002

Cloning of mouse ojoplano, a reticular cytoplasmic protein expressed during embryonic development

scientific journal article

Close association of olfactory placode precursors and cranial neural crest cells does not predestine cell mixing

scientific article

Combining computational prediction of cis-regulatory elements with a new enhancer assay to efficiently label neuronal structures in the medaka fish

scientific article (publication date: 2011)

Comparative epigenomics in distantly related teleost species identifies conserved cis-regulatory nodes active during the vertebrate phylotypic period

scientific article published on 7 April 2014

Correction: CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

scientific article published on 20 April 2017

Correction: Dynamics of in vivo ASC speck formation.

scientific article published on 13 September 2017

Correction: Handling Permutation in Sequence Comparison: Genome-Wide Enhancer Prediction in Vertebrates by a Novel Non-Linear Alignment Scoring Principle.

scientific article published on 23 November 2015

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

scientific article published on November 2016

Corrigendum: Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal

scientific article published in December 2017

Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI)

article

De novo neurogenesis by targeted expression of atoh7 to Müller glia cells

scientific article published on 11 April 2016

Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3.

scientific article published on 15 June 2015

Development of pigment-cup eyes in the polychaete Platynereis dumerilii and evolutionary conservation of larval eyes in Bilateria.

scientific article published in March 2002

Differences in vertebrate microRNA expression

scholarly article

Differential responsiveness of distinct retinal domains to Atoh7.

scientific article published on 21 August 2014

Differentiation of the vertebrate retina is coordinated by an FGF signaling center

scientific article

Digital scanned laser light-sheet fluorescence microscopy (DSLM) of zebrafish and Drosophila embryonic development

scientific article

Direct interaction of geminin and Six3 in eye development

scientific article

Disruption of mesoderm and axis formation in fish by ectopic expression of activin variants: the role of maternal activin.

scientific article published in June 1994

Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia

scientific article published on 5 June 2014

Dynamics of ASC speck formation during skin inflammatory responses in vivo

article

Dynamics of in vivo ASC speck formation

scientific article published on 12 July 2017

Ectopic lens induction in fish in response to the murine homeobox gene Six3.

scientific article published in December 1996

Efficient activation of gene expression using a heat-shock inducible Gal4/Vp16-UAS system in medaka

scientific article

Efficient single-copy HDR by 5' modified long dsDNA donors

article published in 2018

Efficient single-copy HDR by 5' modified long dsDNA donors

Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase

scientific article published on 18 September 2013

Enhanced in vivo-imaging in fish by optimized anaesthesia, fluorescent protein selection and removal of pigmentation

Enhanced in vivo-imaging in medaka by optimized anaesthesia, fluorescent protein selection and removal of pigmentation

scientific article published on 07 March 2019

Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence

scientific article published on August 2013

Evolution of the bilaterian larval foregut

scientific article (publication date: 4 January 2001)

Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina

scientific article

Expression of a medaka (Oryzias latipes) Bar homologue in the differentiating central nervous system and retina

scientific article

Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses

scientific article

Expression screening using a Medaka cDNA library identifies evolutionarily conserved regulators of the p53/Mdm2 pathway

scientific article published on 8 October 2015

Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

scientific article

Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy

scientific article

Fate restriction and multipotency in retinal stem cells

scientific article published in December 2011

Fish genomes flying. Symposium on Medaka Genomics

scientific article published in February 2003

Five Nkx5 genes show differential expression patterns in anlagen of sensory organs in medaka: insight into the evolution of the gene family

article

GSD: a genetic screen database.

scientific article published on July 2004

Gastrulation in an annual killifish: Molecular and cellular events during germ layer formation in Austrolebias.

scientific article

Generation of DNA Constructs Using the Golden GATEway Cloning Method

scientific article published in January 2017

Genetic and functional insights into the fractal structure of the heart

scientific article published on 19 August 2020

Genetic dissection of the formation of the forebrain in Medaka, Oryzias latipes.

scientific article published in July 2004

Genomic and phenotypic characterization of a wild medaka population: towards the establishment of an isogenic population genetic resource in fish

scientific article published on 20 March 2014

Golden GATEway cloning--a combinatorial approach to generate fusion and recombination constructs

scientific article

Graded interference with FGF signalling reveals its dorsoventral asymmetry at the mid-hindbrain boundary

scientific article published in December 1999

Handling Permutation in Sequence Comparison: Genome-Wide Enhancer Prediction in Vertebrates by a Novel Non-Linear Alignment Scoring Principle.

scientific article published on 27 October 2015

Highly efficient zebrafish transgenesis mediated by the meganuclease I-SceI.

scientific article published in January 2004

Hold your breath!

scientific article

Hox Function Is Required for the Development and Maintenance of the Drosophila Feeding Motor Unit.

scientific article published on 13 January 2016

I-SceI meganuclease mediates highly efficient transgenesis in fish.

scientific article

Identification and lineage tracing of two populations of somatic gonadal precursors in medaka embryos

scientific article published on 7 April 2006

Identification of starmaker-like in medaka as a putative target gene of Pax2 in the otic vesicle.

scientific article published in November 2009

Identification, visualization and clonal analysis of intestinal stem cells in fish

scientific article published on 30 August 2016

In vivo identification and validation of novel potential predictors for human cardiovascular diseases

scientific article published on 17 December 2021

In vivo time-lapse imaging in medaka--n-heptanol blocks contractile rhythmical movements.

scientific article

In vivo validation of a computationally predicted conserved Ath5 target gene set

scientific article

Individual cell migration serves as the driving force for optic vesicle evagination

scientific article published in August 2006

Instantaneous isotropic volumetric imaging of fast biological processes

scientific article published on 29 April 2019

Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome

scientific article published on February 2011

Introducing Biomedisa as an open-source online platform for biomedical image segmentation

scientific article published on 04 November 2020

Large-scale expression screening by automated whole-mount in situ hybridization

scientific article published in July 2004

Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signaling activity in leading cells

article published in the Proceedings of the National Academy of Sciences of the United States of America

Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene

scientific article published on 01 June 1994

Loss and Rebirth of the Animal Microtubule Organizing Center: How Maternal Expression of Centrosomal Proteins Cooperates with the Sperm Centriole in Zygotic Centrosome Reformation

scientific article published on 9 March 2018

Loss of eyes in zebrafish caused by mutation of chokh/rx3.

scientific article

Loss of maternal Smad5 in zebrafish embryos affects patterning and morphogenesis of optic primordia

scientific article published in May 2003

MEPD: a Medaka gene expression pattern database

scientific article published on January 2003

MEPD: a resource for medaka gene expression patterns

scientific article published on 06 May 2005

MEPD: medaka expression pattern database, genes and more

scientific article published on 7 October 2015

Medaka and zebrafish, an evolutionary twin study.

scientific article published on July 2004

Medaka eyeless is the key factor linking retinal determination and eye growth.

scientific article published in October 2001

Medaka spalt acts as a target gene of hedgehog signaling.

scientific article published in August 1997

Medaka--a model organism from the far East

scientific article

Medial floor plate formation in zebrafish consists of two phases and requires trunk-derived Midkine-a

scientific article published on April 2005

Meganuclease and transposon mediated transgenesis in medaka

scientific article

Morphogenesis of the optic tectum in the medaka (Oryzias latipes): a morphological and molecular study, with special emphasis on cell proliferation

scientific article

Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships

scientific article published on 23 December 2006

Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria

scientific article published on 01 July 2004

Mutations affecting retina development in Medaka.

scientific article

Mutations affecting retinotectal axonal pathfinding in Medaka, Oryzias latipes

scientific article

Mutations affecting somite formation in the Medaka (Oryzias latipes)

scientific article published on 01 July 2004

New genes in the evolution of the neural crest differentiation program

scientific article (publication date: 2007)

Nlcam modulates midline convergence during anterior neural plate morphogenesis

scientific article published on 11 December 2009

Noninvasive In Toto Imaging of the Thymus Reveals Heterogeneous Migratory Behavior of Developing T Cells.

scientific article

Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth

scholarly article by Alicia Pérez Saturnino published in October 2018

Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth

Novel components of germline sex determination acting downstream of foxl3 in medaka

scholarly article by Mariko Kikuchi published in October 2018

Numb/Numbl-Opo antagonism controls retinal epithelium morphogenesis by regulating integrin endocytosis.

scientific article

One for all--a highly efficient and versatile method for fluorescent immunostaining in fish embryos

scientific article

Optical sectioning deep inside live embryos by selective plane illumination microscopy

scientific article (publication date: 13 August 2004)

Polychaete trunk neuroectoderm converges and extends by mediolateral cell intercalation.

scientific article

Quantitative analysis of embryogenesis: a perspective for light sheet microscopy

scientific article published on December 2012

Quantitative morphometric analysis of adult teleost fish by X-ray computed tomography

scientific article published in Scientific Reports

Rapid chromosomal assignment of medaka mutants by bulked segregant analysis

scientific article published in March 2004

Rapid identification of PAX2/5/8 direct downstream targets in the otic vesicle by combinatorial use of bioinformatics tools

scientific article published on October 2008

Recent advances in meganuclease-and transposon-mediated transgenesis of medaka and zebrafish

scientific article published on January 2008

Reconstructing the eyes of Urbilateria.

scientific article

Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy

scientific article

Retinal neurogenesis

scientific article published on January 2014

Retinal stem cells modulate proliferative parameters to coordinate post-embryonic morphogenesis in the eye of fish

Retinal stem cells modulate proliferative parameters to coordinate post-embryonic morphogenesis in the eye of fish

scientific article published on 26 March 2019

Rx-Cre, a tool for inactivation of gene expression in the developing retina

scientific article published in August 2006

Shaping the vertebrate eye.

scientific article published on 08 October 2009

Six3 and Six6 activity is modulated by members of the groucho family

scientific article

Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye

scientific journal article

Six3, a medaka homologue of the Drosophila homeobox gene sine oculis is expressed in the anterior embryonic shield and the developing eye.

scientific article published in June 1998

Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo

scientific article published on 23 April 2015

Swift Large-scale Examination of Directed Genome Editing

scientific article published on 05 March 2019

TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonism.

scientific article

TRIM25 has a dual function in the p53/Mdm2 circuit

scientific article

The BMP-related protein radar: a maintenance factor for dorsal neuroectoderm cells?

scientific article published in July 1999

The PAR complex controls the spatiotemporal dynamics of F-actin and the MTOC in directionally migrating leukocytes

scientific article

The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma.

scientific article published on November 1992

The centriolar satellite protein SSX2IP promotes centrosome maturation

scientific article

The conditional medaka mutation eyeless uncouples patterning and morphogenesis of the eye.

scientific article published in May 2000

The discovery, positioning and verification of a set of transcription-associated motifs in vertebrates

scientific article published on 2 December 2005

The genomic and genetic toolbox of the teleost medaka (Oryzias latipes)

scientific article

The homeobox gene Xbh1 cooperates with proneural genes to specify ganglion cell fate within the Xenopus neural retina

scientific article published on 21 April 2004

The medaka mutation tintachina sheds light on the evolution of V-ATPase B subunits in vertebrates

scientific article published on 14 November 2013

The midbrain-hindbrain boundary genetic cascade is activated ectopically in the diencephalon in response to the widespread expression of one of its components, the medaka gene Ol-eng2.

scientific article published in September 1999

Transgenesis in fish: efficient selection of transgenic fish by co-injection with a fluorescent reporter construct

scientific article published in January 2006

Trawler: de novo regulatory motif discovery pipeline for chromatin immunoprecipitation

scientific article published on 24 June 2007

Tumor angiogenesis is caused by single melanoma cells in a manner dependent on reactive oxygen species and NF-κB.

scientific article published on 10 July 2013

Tyrosine phosphorylation of LRP6 by Src and Fer inhibits Wnt/β-catenin signalling

scientific article

Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions

scientific article

Using Trawler_standalone to discover overrepresented motifs in DNA and RNA sequences derived from various experiments including chromatin immunoprecipitation

scientific article

Wnt11 acts on dermomyotome cells to guide epaxial myotome morphogenesis

scientific article published on 06 May 2022

Zebrafish Radar: a new member of the TGF-beta superfamily defines dorsal regions of the neural plate and the embryonic retina

scientific article published on 01 February 1995

Zebrafish and medaka: model organisms for a comparative developmental approach of brain asymmetry

scientific article

iDamIDseq and iDEAR: an improved method and computational pipeline to profile chromatin-binding proteins.

scientific article published on 5 October 2016

ojoplano-mediated basal constriction is essential for optic cup morphogenesis.

scientific article published on July 2009

yap1b, a divergent Yap/Taz family member, cooperates with yap1 in survival and morphogenesis via common transcriptional targets

scientific article published on 21 June 2019

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