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List of works by Antonello Pileggi

A new home for pancreatic islet transplants: the bone marrow

scientific article published on October 2013

A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations

scientific article published in July 2005

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic beta cell

scientific article

Absence of M-CSF-dependent tissue macrophages does not improve delayed function of islet of Langerhans grafts

scientific article published on 01 February 2001

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

scientific article published in March 2003

Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets.

scientific article

Allogeneic islet transplantation

scientific article published on November 2007

Allosensitization of islet allograft recipients

scientific article

Alpha-1 antitrypsin treatment of spontaneously diabetic nonobese diabetic mice receiving islet allografts

scientific article published in March 2008

Alterations of the female reproductive system in recipients of islet grafts

scientific article published in December 2004

Anti-inflammatory properties of exenatide in human pancreatic islets

scientific article published on 07 June 2011

Antiproinflammatory effects of iodixanol (OptiPrep)-based density gradient purification on human islet preparations.

scientific article published on 17 August 2010

Antisense miR-7 impairs insulin expression in developing pancreas and in cultured pancreatic buds

scientific article

Beneficial effects of ischemic preconditioning on pancreas cold preservation

scientific article published on 01 January 2012

Biliary tree stem cells, precursors to pancreatic committed progenitors: evidence for possible life-long pancreatic organogenesis.

scientific article published on September 2013

Bioengineering of an Intraabdominal Endocrine Pancreas

scientific article published in May 2017

Bioengineering the Endocrine Pancreas: Intraomental Islet Transplantation Within a Biologic Resorbable Scaffold

scientific article published on 25 February 2016

Blockade of Leukocyte Function Antigen-1 (LFA-1) in Clinical Islet Transplantation ⬇️

scientific article published on 01 October 2011

C-peptide and glucose values in the peritransplant period after intraportal islet infusions in type 1 diabetes

scientific article

Characterization of pancreatic ductal cells in human islet preparations

scientific article

Combined islet and hematopoietic stem cell allotransplantation: a clinical pilot trial to induce chimerism and graft tolerance

scientific article published on 29 April 2008

Controlled Release of Dexamethasone from Organosilicone Constructs for Local Modulation of Inflammation in Islet Transplantation

scientific article published on 10 July 2015

Correction of diabetes mellitus by transplanting minimal mass of syngeneic islets into vascularized small intestinal segment

scientific article published on 6 September 2013

Cytomegalovirus infection in a recipient of solitary allogeneic islets

scientific article published on 01 May 2006

Dapsone-induced artifactual a1c reduction in islet transplant recipients

scientific article published on 01 March 2007

Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets.

scientific article

Delivery of TAT/PTD-fused proteins/peptides to islets via pancreatic duct.

scientific article published in January 2005

Development of a model of combined bone marrow and small bowel transplantation in swine

scientific article published on 01 September 1998

Device design and materials optimization of conformal coating for islets of Langerhans

scientific article

Differential engraftment of human peripheral blood lymphocytes in various strains of immunodeficient mice

scientific article published on 01 February 2001

Donor islet endothelial cells in pancreatic islet revascularization

scientific article

Early assessment of apoptosis in isolated islets of Langerhans

scientific article published on 01 February 2001

Early assessment of apoptosis in isolated islets of Langerhans

scientific article published on 01 April 2001

Effect of pituitary adenylate cyclase-activating polypeptide in islet transplantation

scientific article published on January 2009

Effect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection

scientific article published on 11 January 2013

Effects of pancreas cold ischemia on islet function and quality.

scientific article published in June 2009

Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device

scientific article published in January 2009

Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1.

scientific article published in August 2002

Engineering human renal epithelial cells for transplantation in regenerative medicine.

scientific article published on 13 April 2017

Evaluation of Ex-Vivo Gene Transfer of Fadd-Dn to Pancreatic Islets

scientific article published on 26 October 2001

Exenatide and rare adverse events

scientific article published on 01 May 2008

Expression of Heme Oxygenase-1 Mediated by A Protein Transduction Domain Protects Insulin Producing Cells from Cytokine- Induced Cytotoxicity.

scientific article

Factors that affect human islet isolation

scientific article published on March 2008

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

scientific article published on 7 July 2015

Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells

scientific article published on 21 December 2011

HO-1 upregulation protects the pancreatic cell line betaTC3 from cytokines and Fas-induced apoptosis.

scientific article published on February 2001

Heme oxygenase-1 fused to a TAT peptide transduces and protects pancreatic beta-cells.

scientific article published on June 2003

Heme oxygenase-1 upregulation protects against intestinal ischemia/reperfusion injury: a laboratory based study

scientific article published on 07 July 2006

High-resolution, noninvasive longitudinal live imaging of immune responses ⬇️

scientific article

Human alpha 1-antitrypsin therapy induces fatal anaphylaxis in non-obese diabetic mice.

scientific article published on 28 August 2008

Immunosuppression and procedure-related complications in 26 patients with type 1 diabetes mellitus receiving allogeneic islet cell transplantation

scientific article published in December 2005

Impact of Statins on the Coagulation Status of Type 2 Diabetes Patients Evaluated by a Novel Thrombin-Generation Assay

scientific article published on 01 August 2012

Impact of pancreatic cold preservation on rat islet recovery and function.

scientific article

Improved metabolic control and quality of life in seven patients with type 1 diabetes following islet after kidney transplantation

scientific article

Induced Heme Oxygenase-1 Upregulation Protects Pancreatic Beta Cells from Apoptosis In Vitro

scientific article published on 04 April 2001

Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial

scientific article published on March 2012

Inflammation-Mediated Regulation of MicroRNA Expression in Transplanted Pancreatic Islets.

scientific article published on 10 May 2012

Influence of in vitro and in vivo oxygen modulation on β cell differentiation from human embryonic stem cells

scientific article

Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes

scientific article published on 29 October 2008

Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation

scientific article published on 08 December 2007

Insulin2 gene (Ins2) transcription by NOD bone marrow-derived cells does not influence autoimmune diabetes development in NOD-Ins2 knockout mice.

scientific article

Intracardial embryonic delivery of developmental modifiers in utero

scientific article published in September 2012

Intravital imaging of cytotoxic T lymphocytes

scientific article published in January 2014

Ischemic preconditioning improves islet recovery after pancreas cold preservation

scientific article published in January 2009

Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience

scientific article published in August 2005

Islet-Derived eATP Fuels Autoreactive CD8+ T Cells and Facilitates the Onset of Type 1 Diabetes

scientific article published on 31 July 2018

Late Epstein Barr virus reactivation in islet after kidney transplantation

scientific article published in November 2008

Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7

scientific article published on 18 December 2012

Long-term insulin independence and improvement in insulin secretion after supplemental islet infusion under exenatide and etanercept

scientific article published on December 2008

Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody.

scientific article

Long-term metabolic and hormonal effects of exenatide on islet transplant recipients with allograft dysfunction

scientific article published in January 2009

Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold

scientific article published on January 2009

Macroporous three-dimensional PDMS scaffolds for extrahepatic islet transplantation

scientific article published on 2 October 2012

Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials.

scientific article published on August 2013

Mesenchymal stem cells for the treatment of diabetes

scientific article

Mesenchymal stromal (stem) cells to improve solid organ transplant outcome: lessons from the initial clinical trials

scientific article

MicroRNAs in islet immunobiology and transplantation

scientific article published on December 2013

Near infrared optical projection tomography for assessments of β-cell mass distribution in diabetes research

scientific article published on 12 January 2013

Neonatal porcine pancreatic cell clusters as a potential source for transplantation in humans: characterization of proliferation, apoptosis, xenoantigen expression and gene delivery with recombinant AAV.

scientific article

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release

scientific article

Nonalbumin proteinuria in islet transplant recipients

scientific article published on 29 October 2009

Noninvasive in vivo imaging of pancreatic islet cell biology

scientific article

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

scientific article published on 10 December 2012

Nonlethal conditioning for the induction of allogeneic chimerism and tolerance to islet allografts.

scientific article published in April 2003

Overcoming the challenges now limiting islet transplantation: a sequential, integrated approach

scientific article

P2X receptors and diabetes

scientific article

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

scientific article published in March 2018

Patterns of engraftment in different strains of immunodeficient mice reconstituted with human peripheral blood lymphocytes

scientific article published on 01 July 2001

Pharmacogenomics and pharmacogenetics of thiazolidinediones: role in diabetes and cardiovascular risk factors

scientific article

Pharmacokinetic study of intraarterial local intestinal infusion of tacrolimus

scientific article published on 01 September 2000

Pleiotropic effects of PPARγ agonist on hemostatic activation in type 2 diabetes mellitus.

scientific article published in May 2013

Point: steady progress and current challenges in clinical islet transplantation

scientific article published on August 2009

Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy

scientific article

Proangiogenic hydrogels within macroporous scaffolds enhance islet engraftment in an extrahepatic site

scientific article published on 09 August 2013

Prolactin supplementation to culture medium improves beta-cell survival.

scientific article

Prolonged islet allograft survival by alpha-1 antitrypsin: the role of humoral immunity

scientific article published in March 2008

Prolonged islet allograft survival in diabetic NOD mice by targeting CD45RB and CD154.

scientific article published in April 2003

Prolonged survival of allogeneic islet grafts in NOD mice treated with a combination of anti-CD45RB and anti-CD154 antibodies

scientific article published on 01 February 2001

Protecting pancreatic beta-cells

scientific article

Quantitative differential expression analysis reveals miR-7 as major islet microRNA.

scientific article

Rapamycin impairs beta-cell proliferation in vivo.

scientific article published in March 2008

Rapamycin impairs in vivo proliferation of islet beta-cells.

scientific article published in December 2007

Re-engineering islet cell transplantation.

scientific article published on 23 March 2015

Real-time immune cell interactions in target tissue during autoimmune-induced damage and graft tolerance

scientific article

Recurrence of autoimmunity following pancreas transplantation

scientific article

Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.

scientific article

Recurrent hypoglycemia exacerbates cerebral ischemic damage in streptozotocin-induced diabetic rats

scientific article published on 31 March 2011

Recurrent hypoglycemia increases oxygen glucose deprivation-induced damage in hippocampal organotypic slices

scientific article published on 02 April 2011

Rescue purification maximizes the use of human islet preparations for transplantation

scientific article published in January 2005

Resolution of severe atopic dermatitis after tacrolimus withdrawal.

scientific article

Restoration of hypoglycemia awareness after islet transplantation

scientific article published on 12 August 2008

Reversal of diabetes by pancreatic islet transplantation into a subcutaneous, neovascularized device

scientific article published on May 2006

Shipment of human islets for transplantation

scientific article published on 01 April 2007

Simple measures to monitor beta-cell mass and assess islet graft dysfunction

scientific article published on 6 December 2006

Stable renal function after islet transplantation: importance of patient selection and aggressive clinical management.

scientific article published on March 2009

Systemic overexpression of interleukin-10 fails to protect allogeneic islet transplants in nonobese diabetic mice.

scientific article published in August 2005

Targeted bone marrow radioablation with 153Samarium-lexidronam promotes allogeneic hematopoietic chimerism and donor-specific immunologic hyporesponsiveness

scientific article published in March 2004

Targeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice ⬇️

scientific article published on July 30, 2011

The anterior chamber of the eye as a clinical transplantation site for the treatment of diabetes: a study in a baboon model of diabetes

scientific article published on March 2011

The effect of simultaneous CD154 and LFA-1 blockade on the survival of allogeneic islet grafts in nonobese diabetic mice.

scientific article published in December 2003

The impact of cell surface PEGylation and short-course immunotherapy on islet graft survival in an allogeneic murine model

scientific article published on 30 November 2016

The l-isoform but not d-isoforms of a JNK inhibitory peptide protects pancreatic beta-cells

scientific article published on 02 January 2007

The purinergic system in allotransplantation

scientific article published on 16 January 2014

The thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretion

scientific article (publication date: October 2011)

The use of exenatide in islet transplant recipients with chronic allograft dysfunction: safety, efficacy, and metabolic effects

scientific article published on 01 July 2008

Transdisciplinary approach to restore pancreatic islet function.

scientific article

Transduction of TAT/PTD Antiapoptotic Fusion Proteins in Pancreatic Islets

scientific article published on 07 November 2001

Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector

scientific article published on 01 February 2002

Transplantation: current developments and future directions; the future of clinical islet transplantation as a cure for diabetes

scientific article

Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion

scientific article published in December 2015

beta-Cell specific cytoprotection by prolactin on human islets

scientific article

c-Jun N-terminal kinase 1 is deleterious to the function and survival of murine pancreatic islets.

scientific article

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