List of works - Maria Hernandez-Fuentes

A 'biomarker signature' for tolerance in transplantation

scientific article published on 17 August 2010

A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft.

scientific article published on 28 January 2015

A new method for the simultaneous analysis of growth and death of immunophenotypically defined cells in culture

article

A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.

scientific article

Accurate apoptosis measurement requires quantification of loss of expression of surface antigens and cell fragmentation

scientific article published on 01 April 2006

An analysis of lymphocyte phenotype after steroid avoidance with either alemtuzumab or basiliximab induction in renal transplantation

scientific article published on 5 March 2012

Analysis of the peripheral T-cell repertoire in kidney transplant patients

scientific article published on 27 October 2010

B-lymphocytes support and regulate indirect T-cell alloreactivity in individual patients with chronic antibody-mediated rejection

article

Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?

scientific article published on 21 June 2016

Biomarkers of tolerance.

scientific article published on August 2013

Biomarkers of tolerance: searching for the hidden phenotype

scientific article

CD4+CD25+ regulatory T cells do not significantly contribute to direct pathway hyporesponsiveness in stable renal transplant patients

scientific article published on June 2003

Chronic graft loss. Immunological and non-immunological factors.

scientific article

Circulating vascular progenitor cells and central arterial stiffness in polycystic ovary syndrome.

scientific article

Comparison of the direct and indirect pathways of allorecognition in chronic allograft failure

scientific article published on 01 February 2001

Corrigendum: Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses.

scientific article published on 22 February 2018

Cross-validation of IFN-γ Elispot assay for measuring alloreactive memory/effector T cell responses in renal transplant recipients.

scientific article published on 13 June 2013

Design and Implementation of the International Genetics and Translational Research in Transplantation Network

scientific article

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

scientific article

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

scientific article

Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples

scientific article published on 02 March 2019

Differential role of naïve and memory CD4 T-cell subsets in primary alloresponses.

scientific article published on August 2010

Establishing the optimal method to estimate the frequencies of alloreactive CD4+ T cells

article

Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro

scientific article published in March 2005

Gene expression biomarkers for kidney transplant rejection-The entire landscape-Author's reply

article

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.

scientific article

Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis

scientific article

Graft dysfunction in chronic antibody-mediated rejection correlates with B-cell-dependent indirect antidonor alloresponses and autocrine regulation of interferon-γ production by Th1 cells.

scientific article published on 14 December 2016

Human CD4+CD25+ T cells regulate CD8+ T-cell activation

scientific article published on 01 November 2002

Human acute kidney injury is associated with a proinflammatory phenotype. ⬇️

scientific article published on 17 March 2014

IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses

scientific article published on 22 January 2016

Identification of a B cell signature associated with renal transplant tolerance in humans.

scientific article

Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells

scientific article

Immunologic monitoring.

scientific article published on December 2003

Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells

scientific article published on 31 January 2014

In vitro assays for immune monitoring in transplantation.

scientific article published on January 2006

Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients

scientific article published on 28 July 2016

Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery.

scientific article

Lack of adjustment for confounding could lead to misleading conclusions

scientific article published on 16 August 2017

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study

scientific article published in February 2018

Loss of Direct and Maintenance of Indirect Alloresponses in Renal Allograft Recipients: Implications for the Pathogenesis of Chronic Allograft Nephropathy

scientific article published on 01 December 2001

Loss of lineage antigens is a common feature of apoptotic lymphocytes.

scientific article

Lyoplate-based multiparameter flow cytometry for the analysis of T cell subsets in human immuno-monitoring studies.

scientific article published on 23 November 2011

Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses

scientific article published on 21 December 2017

Multiparameter immune profiling of operational tolerance in liver transplantation

scientific article published in February 2007

Non-invasive biomarkers to guide management following renal transplantation: the need for a multiplatform approach

scientific article published on February 2013

Pretransplant Donor-Specific Helper T Cell Reactivity as a Tool for Tailoring the Individual Need for Immunosuppression

scientific article published on 01 September 2001

Promoting transplantation tolerance; adoptive regulatory T cell therapy

scientific article published on May 2013

Reduced TCR-signalling contributes to impaired Th17 responses in tolerant kidney transplant recipients.

scientific article published on 12 September 2017

Retrospective tissue typing of the kidney donor from recipient urine

scientific article published on 16 July 2008

Reversibility with Interleukin-2 Suggests that T Cell Anergy Contributes to Donor-Specific Hyporesponsiveness in Renal Transplant Patients

scientific article published on 01 December 2002

Significant frequencies of T cells with indirect anti-donor specificity in heart graft recipients with chronic rejection

scientific article

Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.

scientific article published on 7 February 2018

The alloresponse.

scientific article

The genetic determinants of renal allograft rejection

scientific article published on 28 May 2018

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

scientific article published on 28 March 2019

The role of T-cell anergy in the maintenance of donor-specific hyporesponsiveness in renal transplant recipients

scientific article published on 01 February 2001

The role of the allograft in the induction of donor-specific T cell hyporesponsiveness.

scientific article

Tolerant T cells display impaired trafficking ability.

scientific article published in July 2005

List of works by Maria Hernandez-Fuentes

A 'biomarker signature' for tolerance in transplantation

A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft.

A new method for the simultaneous analysis of growth and death of immunophenotypically defined cells in culture

A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.

Accurate apoptosis measurement requires quantification of loss of expression of surface antigens and cell fragmentation

An analysis of lymphocyte phenotype after steroid avoidance with either alemtuzumab or basiliximab induction in renal transplantation

Analysis of the peripheral T-cell repertoire in kidney transplant patients

B-lymphocytes support and regulate indirect T-cell alloreactivity in individual patients with chronic antibody-mediated rejection

Biomarkers of Tolerance in Kidney Transplantation: Are We Predicting Tolerance or Response to Immunosuppressive Treatment?

Biomarkers of tolerance.

Biomarkers of tolerance: searching for the hidden phenotype

CD4+CD25+ regulatory T cells do not significantly contribute to direct pathway hyporesponsiveness in stable renal transplant patients

Chronic graft loss. Immunological and non-immunological factors.

Circulating vascular progenitor cells and central arterial stiffness in polycystic ovary syndrome.

Comparison of the direct and indirect pathways of allorecognition in chronic allograft failure

Corrigendum: Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses.

Cross-validation of IFN-γ Elispot assay for measuring alloreactive memory/effector T cell responses in renal transplant recipients.

Design and Implementation of the International Genetics and Translational Research in Transplantation Network

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

Development of a multivariable gene-expression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in cross-sectional and longitudinal samples

Differential role of naïve and memory CD4 T-cell subsets in primary alloresponses.

Establishing the optimal method to estimate the frequencies of alloreactive CD4+ T cells

Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro

Gene expression biomarkers for kidney transplant rejection-The entire landscape-Author's reply

Genetic loci influencing kidney function and chronic kidney disease

Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4.

Genome-wide sequencing of cellular microRNAs identifies a combinatorial expression signature diagnostic of sepsis

Graft dysfunction in chronic antibody-mediated rejection correlates with B-cell-dependent indirect antidonor alloresponses and autocrine regulation of interferon-γ production by Th1 cells.

Human CD4+CD25+ T cells regulate CD8+ T-cell activation

Human acute kidney injury is associated with a proinflammatory phenotype. ⬇️

IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses

Identification of a B cell signature associated with renal transplant tolerance in humans.

Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells

Immunologic monitoring.

Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells

In vitro assays for immune monitoring in transplantation.

Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients

Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery.

Lack of adjustment for confounding could lead to misleading conclusions

Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study

Loss of Direct and Maintenance of Indirect Alloresponses in Renal Allograft Recipients: Implications for the Pathogenesis of Chronic Allograft Nephropathy

Loss of lineage antigens is a common feature of apoptotic lymphocytes.

Lyoplate-based multiparameter flow cytometry for the analysis of T cell subsets in human immuno-monitoring studies.

Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses

Multiparameter immune profiling of operational tolerance in liver transplantation

Non-invasive biomarkers to guide management following renal transplantation: the need for a multiplatform approach

Pretransplant Donor-Specific Helper T Cell Reactivity as a Tool for Tailoring the Individual Need for Immunosuppression

Promoting transplantation tolerance; adoptive regulatory T cell therapy

Reduced TCR-signalling contributes to impaired Th17 responses in tolerant kidney transplant recipients.

Retrospective tissue typing of the kidney donor from recipient urine

Reversibility with Interleukin-2 Suggests that T Cell Anergy Contributes to Donor-Specific Hyporesponsiveness in Renal Transplant Patients

Significant frequencies of T cells with indirect anti-donor specificity in heart graft recipients with chronic rejection

Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.

The alloresponse.

The genetic determinants of renal allograft rejection

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

The role of T-cell anergy in the maintenance of donor-specific hyporesponsiveness in renal transplant recipients

The role of the allograft in the induction of donor-specific T cell hyporesponsiveness.

Tolerant T cells display impaired trafficking ability.