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List of works by Moses Rodriguez

5-Fluorouracil and levamisole exacerbate demyelination in susceptible mice infected with Theiler's virus

scientific article published in September 1997

A Comparison of Human Natural Monoclonal Antibodies and Aptamer Conjugates for Promotion of CNS Remyelination: Where Are We Now and What Comes Next?

scientific article published on 20 February 2018

A function of myelin is to protect axons from subsequent injury: implications for deficits in multiple sclerosis

scientific article published in April 2003

A human antibody that promotes remyelination enters the CNS and decreases lesion load as detected by T2-weighted spinal cord MRI in a virus-induced murine model of MS.

scientific article published on 19 August 2004

A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens

scientific journal article

A monoclonal natural autoantibody that promotes remyelination suppresses central nervous system inflammation and increases virus expression after Theiler's virus-induced demyelination

scientific article published in January 1996

A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis.

scientific article published on 28 May 2015

A new humanized HLA transgenic mouse model of multiple sclerosis expressing class II on mouse CD4 T cells.

scientific article

A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease.

scientific article

A recombinant human IgM promotes myelin repair after a single, very low dose

scientific article published on 01 April 2007

A single dose of a neuron-binding human monoclonal antibody improves brainstem NAA concentrations, a biomarker for density of spinal cord axons, in a model of progressive multiple sclerosis.

scientific article published on 29 April 2015

A single dose of neuron-binding human monoclonal antibody improves spontaneous activity in a murine model of demyelination

scientific article (publication date: 2011)

Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice

scientific article published on 28 May 2015

Abrogation of resistance to Theiler's virus-induced demyelination in C57BL mice by total body irradiation

scientific article

Absence of IFN-γ increases brain pathology in experimental autoimmune encephalomyelitis-susceptible DRB1*0301.DQ8 HLA transgenic mice through secretion of proinflammatory cytokine IL-17 and induction of pathogenic monocytes/microglia into the centra

scientific article

Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

scientific article published on February 1998

Absence of perforin expression confers axonal protection despite demyelination.

scientific article published on 16 November 2006

Activated microglia stimulate transcriptional changes in primary oligodendrocytes via IL-1beta

scientific article published on 02 August 2006

Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair.

scientific article

Anti-mu treatment suppresses immunoglobulin light-chain gene expression and Peyer's patch development

scientific article published on 01 April 1989

Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody

scientific article published on February 2004

Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease

scientific article

Antibody-mediated remyelination operates through mechanism independent of immunomodulation

scientific article published on 01 January 2004

Antigens to viral capsid and non-capsid proteins are present in brain tissues and antibodies in sera of Theiler's virus-infected mice

scientific article

Antiviral effects of a transgenic RNA-dependent RNA polymerase

scientific article

Applications of SPR for the characterization of molecules important in the pathogenesis and treatment of neurodegenerative diseases

scientific article

Assessment of hindlimb gait as a powerful indicator of axonal loss in a murine model of progressive CNS demyelination

scientific article published on September 2000

Autoantibodies with enzymatic properties in human autoimmune diseases

scientific article

Brainstem 1H nuclear magnetic resonance (NMR) spectroscopy: marker of demyelination and repair in spinal cord

scientific article published on October 2009

CD4+ T cells are important for clearance of DA strain of TMEV from the central nervous system of SJL/J mice

scientific article published on 19 July 2004

CD8(+) T cells in multiple sclerosis.

scientific article published on 06 July 2013

CD8+ T cells cause disability and axon loss in a mouse model of multiple sclerosis

scientific article

Cellular mechanisms of central nervous system repair by natural autoreactive monoclonal antibodies

scientific article published on December 2009

Cellular sources and targets of IFN-gamma-mediated protection against viral demyelination and neurological deficits.

scientific article published on March 2002

Central nervous system demyelination and remyelination in multiple sclerosis and viral models of disease

scientific article published on October 1, 1992

Chemokine expression in the central nervous system of mice with a viral disease resembling multiple sclerosis: roles of CD4+ and CD8+ T cells and viral persistence.

scientific article

Clearance of Theiler's virus infection depends on the ability to generate a CD8+ T cell response against a single immunodominant viral peptide

scientific article published in September 2003

Clinical implications of benign multiple sclerosis: a 20-year population-based follow-up study.

scientific article

Clonal evolution in Waldenstrom macroglobulinemia highlights functional role of B-cell receptor

scientific article published on January 2001

Cognitive impairment occurs in children and adolescents with multiple sclerosis: results from a United States network

scientific article published on 15 November 2012

Common viruses associated with lower pediatric multiple sclerosis risk ⬇️

scientific article published on June 7, 2011

Complementation between specific HLA-DR and HLA-DQ genes in transgenic mice determines susceptibility to experimental autoimmune encephalomyelitis

scientific article published on 01 March 2000

Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells.

scientific article

Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis

scientific article

Delineation of the minimal encephalitogenic epitope of proteolipid protein peptide(91-110) and critical residues required for induction of EAE in HLA-DR3 transgenic mice.

scientific article

Demyelinated axons and motor function are protected by genetic deletion of perforin in a mouse model of multiple sclerosis

scientific article published on September 2009

Differential expression of multiple kallikreins in a viral model of multiple sclerosis points to unique roles in the innate and adaptive immune response.

scientific article

Differential generation of class I H-2D- versus H-2K-restricted cytotoxicity against a demyelinating virus following central nervous system infection

scientific article published in April 1997

Differentiation-specific mRNA expression of a mouse bipotential glial cell line

scientific article published on December 1998

Direct observation of myelination in vivo in the mature human central nervous system. A model for the behaviour of oligodendrocyte progenitors and their progeny

scientific article

Disrupted spatial memory is a consequence of picornavirus infection

scientific article published on 21 August 2006

Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease

scientific article published in December 2004

Dynamic role of kallikrein 6 in traumatic spinal cord injury

scientific journal article

Dynamics of MRI lesion development in an animal model of viral-induced acute progressive CNS demyelination

scientific article published in February 2004

Ebola virus: melatonin as a readily available treatment option.

scientific article

Effect of cyclosporin A, silica quartz dust, and protease inhibitors on virus-induced demyelination

scientific article

Effectors of demyelination and remyelination in the CNS: implications for multiple sclerosis.

scientific article published on April 2007

Efficient central nervous system remyelination requires T cells

scientific article published in May 2003

Enhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the network

scientific article

Enzymatic properties of rat myelencephalon-specific protease

scientific journal article

Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS.

scientific article

Experimental strategies to promote central nervous system remyelination in multiple sclerosis: insights gained from the Theiler's virus model system

scientific article

Expression of T cell receptor V beta transcripts in central nervous system of mice susceptible and resistant to Theiler's virus-induced demyelination

scientific article published in August 1993

Extratrigeminal short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT): new pathophysiologic entity or variation on a theme?

scientific article published on 01 March 2000

Facile assembly of micro- and nanoarrays for sensing with natural cell membranes

scientific article

Failure of treatment with Linomide or oral myelin tolerization to ameliorate demyelination in a viral model of multiple sclerosis

scientific article published on 01 August 1998

Formation of biomembrane microarrays with a squeegee-based assembly method

scientific article

Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection.

scientific article published on November 2003

Genetic deletion of a single immunodominant T-cell response confers susceptibility to virus-induced demyelination.

scientific article published on April 2007

Genetic risk factors for pediatric-onset multiple sclerosis

scientific article published in October 2017

Glial cells as therapeutic targets in progressive multiple sclerosis

scientific article published on 13 May 2019

Growth factor treatment of demyelinating disease: at last, a leap into the light.

scientific article

HLA DR and DQ interaction in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in HLA class II transgenic mice.

scientific article published on 27 September 2005

HLA class II transgenic mice authenticate restriction of myelin oligodendrocyte glycoprotein-specific immune response implicated in multiple sclerosis pathogenesis.

scientific article

HLA-DQ polymorphism influences progression of demyelination and neurologic deficits in a viral model of multiple sclerosis

scientific article

HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice.

scientific article published on April 2009

Have we finally identified an autoimmune demyelinating disease?

scientific article published on 01 November 2009

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

scientific article (publication date: June 2000)

High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance.

scientific article

Human HLA-DR Transgenes Protect Mice from Fatal Virus-Induced Encephalomyelitis and Chronic Demyelination

scientific article

Human antibodies accelerate the rate of remyelination following lysolecithin-induced demyelination in mice

scientific article published on 01 March 2002

Human class I major histocompatibility complex alleles determine central nervous system injury versus repair

scientific article

Human-derived natural antibodies: biomarkers and potential therapeutics

scientific article

ICAM-1 is crucial for protection from TMEV-induced neuronal damage but not demyelination

scientific article published in October 2002

Identification of T cell epitopes on human proteolipid protein and induction of experimental autoimmune encephalomyelitis in HLA class II-transgenic mice.

scientific article published in January 2004

Immune-mediated injury of virus-infected oligodendrocytes A model of multiple sclerosis

scientific article published in December 1986

Immunoglobulin-mediated CNS repair.

scientific article

Immunomodulation using the recombinant monoclonal human B7-DC cross-linking antibody rHIgM12.

scientific article published on February 2006

Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity

scientific article published in July 2004

Importance of oligodendrocyte protection, BBB breakdown and inflammation for remyelination.

scientific article

Improved vision after intravenous immunoglobulin in stable demyelinating optic neuritis

scientific article published on 01 December 1992

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

scientific article published on 01 April 1997

Induction of a gene expression program in dendritic cells with a cross-linking IgM antibody to the co-stimulatory molecule B7-DC.

scientific article

Influence of deletion of T cell receptor V beta genes on the Theiler's virus model of multiple sclerosis

scientific article

Inhibition of Theiler's virus-induced demyelination in vivo by tumor necrosis factor alpha

scientific article published in January 1990

Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE

scientific article published on 01 December 1998

Internalization and sorting of plasma membrane sphingolipid analogues in differentiating oligodendrocytes

scientific article

Intrathecal somatostatin, somatostatin analogs, substance P analog and dynorphin A cause comparable neurotoxicity in rats

scientific article published on 01 January 1990

Intravenous immunoglobulin therapy in multiple sclerosis: progress from remyelination in the Theiler's virus model to a randomised, double-blind, placebo-controlled clinical trial

scientific article

Invited article: human natural autoantibodies in the treatment of neurologic disease

scientific article

Is Multiple Sclerosis an Autoimmune Disease?

scientific article (publication date: 2012)

Kallikrein 6 Regulates Early CNS Demyelination in a Viral Model of Multiple Sclerosis ⬇️

scientific article published on March 21, 2012

Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration

scientific article

Later-onset Fabry disease: an adult variant presenting with the cramp-fasciculation syndrome

scientific article published on 01 March 2006

MRI findings in benign multiple sclerosis are variable

scientific article published on 29 August 2006

MRI in rodent models of brain disorders

scientific article

Membrane lymphotoxin is required for resistance to Theiler's virus infection.

scientific article published in August 2003

Method of identifying natural antibodies for remyelination.

scientific article

Monoclonal autoantibody SCH94.03, which promotes central nervous system remyelination, recognizes an antigen on the surface of oligodendrocytes

scientific article published in February 1996

Monoclonal remyelination-promoting natural autoantibody SCH 94.03: pharmacokinetics and in vivo targets within demyelinated spinal cord in a mouse model of multiple sclerosis

scientific article published in September 1997

More severe neurologic deficits in SJL/J male than female mice following Theiler's virus-induced CNS demyelination.

scientific article published in March 2003

Motor and somatosensory evoked potentials in mice infected with Theiler's murine encephalomyelitis virus

scientific article published in May 1994

Multiple Sclerosis Therapies in Pediatric Patients With Refractory Multiple Sclerosis ⬇️

scientific article published on December 13, 2010

Multiple sclerosis, brain radiotherapy, and risk of neurotoxicity: the Mayo Clinic experience

scientific article published on 11 September 2006

Multiple sclerosis, seizures, and antiepileptics: role of IL-18, IDO, and melatonin.

scientific article

Multiple sclerosis: a unique immunopathological syndrome of the central nervous system

scientific article published on January 1995

Multiple sclerosis: the role of melatonin and N-acetylserotonin.

scientific article published on 16 December 2014

Natural antibodies, intravenous immunoglobulin and their role in autoimmunity, cancer and inflammation

scientific article published on December 2009

Naturally occurring antibodies as therapeutics for neurologic disease: can human monoclonal IgMs replace the limited resource IVIG?

scientific article published on 01 January 2012

Neurotrophin-4/5 promotes proliferation of oligodendrocyte-type-2 astrocytes (O-2A)

scientific article published on 01 September 2000

Neutralization of chemokines RANTES and MIG increases virus antigen expression and spinal cord pathology during Theiler's virus infection

scientific article

Nonequivalence of classical MHC class I loci in ability to direct effective antiviral immunity.

scientific article

Not every patient with multiple sclerosis should be treated at time of diagnosis

scientific article published on 01 April 2006

Novel immunomodulatory approaches for the management of multiple sclerosis

scientific article published on 30 October 2013

Novel roles of the picornaviral 3D polymerase in viral pathogenesis.

scientific article

Oligodendrocyte-reactive O1, O4, and HNK-1 monoclonal antibodies are encoded by germline immunoglobulin genes

scientific article published on 01 December 1995

PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation

scientific article

Pediatric multiple sclerosis

scientific article published on 01 May 2011

Periodic sharp waves in baclofen-induced encephalopathy

scientific article published on July 1988

Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment

scientific article published on 01 January 2009

Polyclonal Ig: an immunopharmacon?

scientific article published on 01 July 1994

Polyclonal and monoclonal antibodies in clinic

scientific article published on January 2014

Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders.

scientific article

Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis.

scientific article

Potential scope of action of tissue kallikreins in CNS immune-mediated disease

scientific article published on 7 July 2006

Preclinical 1 H-Mrs Neurochemical Profiling in Neurological And Psychiatric Disorders ⬇️

scientific article published on July 1, 2012

Preferential expression of myelencephalon-specific protease by oligodendrocytes of the adult rat spinal cord white matter

scientific article published on 01 May 2000

Premenstrual multiple sclerosis pseudoexacerbations: Role of body temperature and prevention with aspirin

scientific article (publication date: July 2006)

Preservation of neurologic function during inflammatory demyelination correlates with axon sparing in a mouse model of multiple sclerosis

scientific article published on 01 January 2002

Prevalence of tremor in multiple sclerosis and associated disability in the Olmsted County population

scientific article published in December 2004

Promotion of remyelination by polyclonal immunoglobulin in Theiler's virus-induced demyelination and in multiple sclerosis ⬇️

scientific article

Pulsed intravenous methylprednisolone therapy in progressive multiple sclerosis: need for a controlled trial

scientific article

Quality of life is favorable for most patients with multiple sclerosis: a population-based cohort study

scientific article published in May 2004

Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study

scientific article

Quantitative PCR analysis of DNA aptamer pharmacokinetics in mice.

scientific article

Quantitative assessment of neurologic deficits in a chronic progressive murine model of CNS demyelination.

scientific article

Relapses and disability accumulation in progressive multiple sclerosis

scientific article

Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange

scientific article published in The Lancet

Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis.

scientific article

Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair

scientific article published on 01 January 2003

Retinocochleocerebral Vasculopathy ⬇️

scientific article published on January 1, 1998

Retraction: Blockade of allergic airway inflammation following systemic treatment with a B7-dendritic cell (PD-L2) cross-linking human antibody

scientific article published on 01 June 2010

Retraction: Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity

scientific article published on 02 November 2010

Retraction: Naturally occurring human IgM antibody that binds B7-DC and potentiates T cell stimulation by dendritic cells

scientific article published on 01 June 2010

Retraction: TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells

scientific article published in June 2010

Role of MHC class II expressing CD4+ T cells in proteolipid protein(91-110)-induced EAE in HLA-DR3 transgenic mice

scientific article published on 01 December 2006

Role of T cells in resistance to Theiler's virus infection

scientific article published in October 1991

STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis

scientific article published on 13 December 2005

Scleromyxedema in a patient with multiple sclerosis and monoclonal gammopathy on interferon beta-1a

scientific article published on 01 February 2004

Seizures in patients with multiple sclerosis: epidemiology, pathophysiology and management ⬇️

scientific article published on October 2009

Short-term treatment with interferon-alpha/beta promotes remyelination, whereas long-term treatment aggravates demyelination in a murine model of multiple sclerosis

scientific article published on 01 March 2000

Spontaneous and induced remyelination in multiple sclerosis and the Theiler's virus model of central nervous system demyelination

scientific article published on October 1995

Spontaneous central nervous system remyelination in strain A mice after infection with the Daniel's (DA) strain of Theiler's virus

scientific article published in January 1996

Subacute encephalomyelitis presenting as stiff-person syndrome: clinical, polygraphic, and pathologic correlations

scientific article

Successful treatment of established relapsing experimental autoimmune encephalomyelitis in mice with a monoclonal natural autoantibody

scientific article published on 01 May 1997

Surface plasmon resonance for high-throughput ligand screening of membrane-bound proteins

scientific article

Surgical therapy for multiple sclerosis tremor: a 12-year follow-up study

scientific article published on 17 January 2012

The CD4-mediated immune response is critical in determining the outcome of infection using Theiler's viruses with VP1 capsid protein point mutations

scientific article

The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps

scientific article

The relevance of animal models in multiple sclerosis research

scientific article published on February 2011

The road to remyelination in demyelinating diseases: current status and prospects for clinical treatment.

scientific article published on June 2013

The role of cellular immune response in Theiler's virus-induced central nervous system demyelination

scientific article published in February 2004

Theiler's murine encephalomyelitis virus as a vaccine candidate for immunotherapy

scientific article

Theiler's virus-associated antigens on the surfaces of cultured glial cells

scientific article published on October 1988

Theiler's virus-induced demyelination in mice immunosuppressed with anti-IgM and in mice expressing the xid gene

scientific article published on January 1990

Therapeutics to promote CNS repair: a natural human neuron-binding IgM regulates membrane-raft dynamics and improves motility in a mouse model of multiple sclerosis.

scientific article published on 19 September 2012

Transgenic expression of Theiler's murine encephalomyelitis virus genes in H-2(b) mice inhibits resistance to virus-induced demyelination

scientific article

Transgenic expression of the 3D polymerase inhibits Theiler's virus infection and demyelination

scientific article published on 16 September 2009

Transgenic expression of viral capsid proteins predisposes to axonal injury in a murine model of multiple sclerosis

scientific article

Treatment of multiple sclerosis in children and adolescents

scientific article published on March 2010

Tumor necrosis factor alpha is reparative via TNFR2 [corrected] in the hippocampus and via TNFR1 [corrected] in the striatum after virus-induced encephalitis

scientific article published on 15 April 2008

Two discreet subsets of CD8 T cells modulate PLP91–110 induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice ⬇️

scientific article published on March 28, 2012

Ultrastructure of multiple sclerosis

scientific article published in January 1994

VP1 and VP2 capsid proteins of Theiler's virus are targets of H-2D-restricted cytotoxic lymphocytes in the central nervous system of B10 mice

scientific article published on December 1995

Viral perturbation of endocrine function: disordered cell function leads to disturbed homeostasis and disease

scientific article published on 01 January 1984

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