List of works - Pär Matsson

A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (fu,cell)

scientific article published on 07 November 2019

A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

scientific article

A high-throughput cell-based method to predict the unbound drug fraction in the brain

scientific article

Addendum to 'Quantifying the impact of transporters on cellular drug permeability'

scientific article published on 24 July 2015

Cell permeability beyond the rule of 5.

scientific article

Comparison of human solute carriers

scientific article

Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9.

scientific article published on February 2016

Computational modeling to predict the functions and impact of drug transporters.

scientific article published on 4 September 2015

Computational prospecting for drug-transporter interactions

scientific article published on 2 April 2013

Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.

scientific article published on 8 March 2011

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

scientific article published on 06 September 2013

Erratum: Structural and conformational determinants of macrocycle cell permeability

scientific article published on 01 July 2017

Exploring the role of different drug transport routes in permeability screening.

scientific article published on January 2005

Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation ⬇️

scientific article

How Big Is Too Big for Cell Permeability?

scientific article

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

scientific article

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

scientific article published on 2 April 2018

Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.

scientific article

Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes

scientific article published on 19 March 2021

Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids

scientific article published on 11 May 2018

Intracellular drug bioavailability: a new predictor of system dependent drug disposition.

scientific article

Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver

scientific article published on 10 April 2013

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

scientific article

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

scientific article

Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2

scientific article

Quantifying the impact of transporters on cellular drug permeability.

scientific article published on 19 March 2015

Rapid measurement of intracellular unbound drug concentrations.

scientific article published on 15 May 2013

Structural and conformational determinants of macrocycle cell permeability

scientific article published on 17 October 2016

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

scientific article published on 13 September 2008

The Need for Speed-Kinetic Limits of Drug Transporters

scientific article published on 24 February 2016

The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition

scientific article published on 9 January 2016

Understanding polymer-lipid solid dispersions--the properties of incorporated lipids govern the crystallisation behaviour of PEG

scientific article published on 10 November 2009

List of works by Pär Matsson

A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (fu,cell)

A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

A high-throughput cell-based method to predict the unbound drug fraction in the brain

Addendum to 'Quantifying the impact of transporters on cellular drug permeability'

Cell permeability beyond the rule of 5.

Comparison of human solute carriers

Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9.

Computational modeling to predict the functions and impact of drug transporters.

Computational prospecting for drug-transporter interactions

Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Erratum: Structural and conformational determinants of macrocycle cell permeability

Exploring the role of different drug transport routes in permeability screening.

Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation ⬇️

How Big Is Too Big for Cell Permeability?

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5

Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.

Influence of Proteome Profiles and Intracellular Drug Exposure on Differences in CYP Activity in Donor-Matched Human Liver Microsomes and Hepatocytes

Intracellular Drug Bioavailability: Effect of Neutral Lipids and Phospholipids

Intracellular drug bioavailability: a new predictor of system dependent drug disposition.

Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2

Quantifying the impact of transporters on cellular drug permeability.

Rapid measurement of intracellular unbound drug concentrations.

Structural and conformational determinants of macrocycle cell permeability

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

The Need for Speed-Kinetic Limits of Drug Transporters

The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition

Understanding polymer-lipid solid dispersions--the properties of incorporated lipids govern the crystallisation behaviour of PEG