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List of works by John F. Bateman

1H NMR spectroscopy of serum reveals unique metabolic fingerprints associated with subtypes of surgically induced osteoarthritis in sheep

scientific article published on 25 July 2012

A [4,5-3H]lysine:[14C]lysine dual-label method to measure lysine hydroxylation in collagen

scientific article published on October 1986

A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats.

scientific article published on 5 April 2016

A microarray approach for comparative expression profiling of the discrete maturation zones of mouse growth plate cartilage.

scientific article published on 8 March 2008

A mouse splice-site mutant and individuals with atypical chromosome 22q11.2 deletions demonstrate the crucial role for crkl in craniofacial and pharyngeal development.

scientific article

A robust method for proteomic characterization of mouse cartilage using solubility-based sequential fractionation and two-dimensional gel electrophoresis

scientific article published on 16 August 2008

ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo

scientific article published on 01 May 2005

Ablation of the miRNA Cluster 24 Has Profound Effects on Extracellular Matrix Protein Abundance in Cartilage

scientific article published on 09 June 2020

Bethlem myopathy and engineered collagen VI triple helical deletions prevent intracellular multimer assembly and protein secretion

scientific article published on 01 July 1999

Breeding Strategy Determines Rupture Incidence in Post-Infarct Healing WARPing Cardiovascular Research

scientific article published on 25 September 2015

Bulldog dwarfism in Dexter cattle is caused by mutations in ACAN.

scientific article published on 22 October 2007

Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis.

scientific article

Cartilage microRNA dysregulation during the onset and progression of mouse osteoarthritis is independent of aggrecanolysis and overlaps with candidates from end-stage human disease.

scientific article published on 16 November 2017

Cartilage proteomics: Challenges, solutions and recent advances ⬇️

scientific article published on February 1, 2008

Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization

scientific article published on 17 January 2015

Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway.

scientific article

Cauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndrome

scientific journal article

Changes in the chondrocyte and extracellular matrix proteome during post-natal mouse cartilage development

scientific article published on 11 October 2011

Chemical cleavage method for the detection of RNA base changes: experience in the application to collagen mutations in osteogenesis imperfecta

scientific article published on 01 January 1993

Clinical phenotypes associated with type II collagen mutations

scientific article published on 18 February 2011

Collagen II is essential for the removal of the notochord and the formation of intervertebral discs

scientific journal article

Collagen VI glycine mutations: perturbed assembly and a spectrum of clinical severity

scientific article published on September 2008

Collagen VI microfibril formation is abolished by an {alpha}2(VI) von Willebrand factor type A domain mutation in a patient with Ullrich congenital muscular dystrophy

scientific article

Collagen X chains harboring Schmid metaphyseal chondrodysplasia NC1 domain mutations are selectively retained and degraded in stably transfected cells

scientific article published on 22 January 2002

Collagen protein abnormalities produced by site-directed mutagenesis of the pro alpha 1(I) gene

scientific article published on 01 January 1989

Comparative proteomic analysis of normal and collagen IX null mouse cartilage reveals altered extracellular matrix composition and novel components of the collagen IX interactome.

scientific article published on 24 March 2013

Competency for nonsense-mediated reduction in collagen X mRNA is specified by the 3' UTR and corresponds to the position of mutations in Schmid metaphyseal chondrodysplasia

scientific article

Comprehensive analysis of collagen metabolism in vitro using [4(3H)]/[14C]proline dual-labeling and polyacrylamide gel electrophoresis

scientific article published on 01 January 1988

Comprehensive profiling of cartilage extracellular matrix formation and maturation using sequential extraction and label-free quantitative proteomics

scientific article

Correlation of clinical and molecular biological abnormalities in osteogenesis imperfecta

scientific article published in January 1989

Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization

scientific article published in January 2010

Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response

scientific article published in November 2012

Deposition and selective degradation of structurally-abnormal type I collagen in a collagen matrix produced by osteogenesis imperfecta fibroblasts in vitro

scientific article published on 01 April 1994

Detection and localization of base changes in RNA using a chemical cleavage method

scientific article published on 01 December 1989

Distinct skeletal abnormalities in four girls with Shprintzen-Goldberg syndrome

scientific article

Dominant collagen VI mutations are a common cause of Ullrich congenital muscular dystrophy

scientific article published on 24 November 2004

Effect of rapamycin on bone mass and strength in the α2(I)-G610C mouse model of osteogenesis imperfecta.

scientific article

Effects of relaxin, pregnancy and parturition on collagen metabolism in the rat pubic symphysis

scientific article published on 01 October 1998

Employing molecular genetics of chondrodysplasias to inform the study of osteoarthritis

scientific article published on February 2009

Epitope specificity of antibodies to type II collagen in rheumatoid arthritis and systemic lupus erythematosus

scientific article published in January 1992

Familial digital arthropathy-brachydactyly

scientific article published on March 2002

Formation of proline metabolites in chick embryo bone: interference with the measurement of free hydroxyproline by ion-exchange chromatography

scientific article published on 01 March 1982

Gelatinase A (MMP-2) activation by skin fibroblasts: dependence on MT1-MMP expression and fibrillar collagen form

scientific article published on 01 June 2001

Generation of a SOX9-tdTomato reporter human iPSC line, MCRIi001-A-2, using CRISPR/Cas9 editing

scientific article published on 19 December 2019

Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing

scientific article published on 23 April 2019

Genetic Disorders of the Extracellular Matrix

scientific article published on 15 February 2019

Genetic diseases of connective tissues: cellular and extracellular effects of ECM mutations

scientific article published on March 2009

Genomic sequence of mouse COL1A1 encoding the collagen propeptides

scientific article published in December 1993

Gingival fibromatosis and Klippel-Trénaunay-Weber syndrome. Case report

scientific article published on 01 May 1995

Global comparative transcriptome analysis of cartilage formation in vivo

scientific article

Heterogeneity in dermatosparaxis is shown by contraction of collagen gels

scientific article published on January 1991

Human cells unable to express decoron produced disorganized extracellular matrix lacking "shape modules" (interfibrillar proteoglycan bridges).

scientific article published in August 1998

Identification of TGFβ-related genes regulated in murine osteoarthritis and chondrocyte hypertrophy by comparison of multiple microarray datasets

scientific article published on 21 July 2018

Identification of Two Independent COL5A1 Variants in Dogs with Ehlers-Danlos Syndrome

scientific article published on 21 September 2019

Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis

scientific article published on 22 September 2020

In vitro expression analysis of collagen biosynthesis and assembly

scientific article published on December 1997

In vivo cellular adaptation to ER stress: survival strategies with double-edged consequences

scientific article published on July 2010

Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis

scientific article published on 12 May 2011

Interaction of collagen alpha1(X) containing engineered NC1 mutations with normal alpha1(X) in vitro. Implications for the molecular basis of schmid metaphyseal chondrodysplasia

scientific article published on 01 May 1999

Introduction of the human pro alpha 1(I) collagen gene into pro alpha 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen

scientific article

Is there an evolutionary relationship between WARP (von Willebrand factor A-domain-related protein) and the FACIT and FACIT-like collagens?

scientific article published in September 2003

Isolated Anxa5+/Sca-1+ perivascular cells from mouse meningeal vasculature retain their perivascular phenotype in vitro and in vivo

scientific article published on 8 May 2007

Kinked collagen VI tetramers and reduced microfibril formation as a result of Bethlem myopathy and introduced triple helical glycine mutations

scientific article published on 13 November 2001

Lethal perinatal osteogenesis imperfecta due to a type I collagen alpha 2(I) Gly to Arg substitution detected by chemical cleavage of an mRNA:cDNA sequence mismatch

scientific article published in January 1992

MT1-MMP-dependent and -independent regulation of gelatinase A activation in long-term, ascorbate-treated fibroblast cultures: regulation by fibrillar collagen

scientific article published in January 2002

Maintaining mRNA integrity during decalcification of mineralized tissues

scientific article

Mammalian skeletogenesis and extracellular matrix: what can we learn from knockout mice?

scientific article published in April 2000

Matrix deposition by a calcifying human osteogenic sarcoma cell line (SAOS-2)

scientific article

Misfolding of collagen X chains harboring Schmid metaphyseal chondrodysplasia mutations results in aberrant disulfide bond formation, intracellular retention, and activation of the unfolded protein response

scientific article published on 4 February 2005

Molecular consequences of dominant Bethlem myopathy collagen VI mutations

article

Multiexon deletions in the type I collagen COL1A2 gene in osteogenesis imperfecta type IB. Molecules containing the shortened alpha2(I) chains show differential incorporation into the bone and skin extracellular matrix

scientific article published in August 1996

Mutations in TRPV4 cause an inherited arthropathy of hands and feet.

scientific article published on 2 October 2011

Mutations in the heparan-sulfate proteoglycan glypican 6 (GPC6) impair endochondral ossification and cause recessive omodysplasia

scientific article published on 28 May 2009

Mutations of COL10A1 in Schmid metaphyseal chondrodysplasia

scientific article

Novel Elements of the Chondrocyte Stress Response Identified Using an in Vitro Model of Mouse Cartilage Degradation

scientific article published on 12 February 2016

Osteogenic capacity of collagen in repair of established periodontal defects

scientific article published on 01 January 1992

Ovine skin collagen dysplasia

scientific article published on 01 December 1982

Precipitation of collagens by polyethylene glycols

scientific article published on 01 September 1984

Premature arthritis is a distinct type II collagen phenotype.

scientific article published on May 2010

Proteasomal degradation of unassembled mutant type I collagen pro-alpha1(I) chains

scientific article published on September 1999

Proteomic analysis of mouse growth plate cartilage

scientific article published on 01 December 2006

Proteomic characterization of mouse cartilage degradation in vitro

scientific article published in October 2008

Proteomics makes progress in cartilage and arthritis research

scientific article published on 07 February 2009

Rapid fractionation of collagen chains and peptides by high-performance liquid chromatography

scientific article published on 01 April 1986

Recurrent Dominant Mutations Affecting Two Adjacent Residues in the Motor Domain of the Monomeric Kinesin KIF22 Result in Skeletal Dysplasia and Joint Laxity

scientific article published in January 2012

Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity

scientific article published on December 2011

Reduced collagen VI causes Bethlem myopathy: a heterozygous COL6A1 nonsense mutation results in mRNA decay and functional haploinsufficiency

scientific article

Regulation of alkaline phosphatase expression in a neonatal rat clonal calvarial cell strain by retinoic acid

scientific article published in February 1988

Reliable and sensitive detection of premature termination mutations using a protein truncation test designed to overcome problems of nonsense-mediated mRNA instability

scientific article published on 01 January 1999

S100A8 and S100A9 in experimental osteoarthritis.

scientific article

Sorting of growth plate chondrocytes allows the isolation and characterization of cells of a defined differentiation status

scientific article published on 01 June 2010

Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function

scientific article

Targeted induction of endoplasmic reticulum stress induces cartilage pathology

scientific article

The N-terminal N5 subdomain of the alpha 3(VI) chain is important for collagen VI microfibril formation

scientific article published on 01 January 2001

The circadian clock in murine chondrocytes regulates genes controlling key aspects of cartilage homeostasis

scientific article published on September 2013

The effect of relaxin on collagen metabolism in the nonpregnant rat pubic symphysis: the influence of estrogen and progesterone in regulating relaxin activity

scientific article published on 01 September 1996

The extracellular matrix protein WARP is a novel component of a distinct subset of basement membranes

scientific journal article

The globular domain of the proalpha 1(I) N-propeptide is not required for secretion, processing by procollagen N-proteinase, or fibrillogenesis of type I collagen in mice

scientific article published on 08 November 2001

The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration

scientific article

The study of collagen structure and function by site-directed mutagenesis of collagen genes

scientific article published on 01 January 1990

The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line

scientific article published on 04 May 2019

Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage

scientific article published on 01 February 2003

Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy

scientific article

Transcriptomics of wild-type mice and mice lacking ADAMTS-5 activity identifies genes involved in osteoarthritis initiation and cartilage destruction.

scientific article published in June 2013

UNCL, the mammalian homologue of UNC-50, is an inner nuclear membrane RNA-binding protein

scientific journal article

Utility of circulating serum miRNAs as biomarkers of early cartilage degeneration in animal models of post-traumatic osteoarthritis and inflammatory arthritis

scientific article published on 9 September 2016

WARP interacts with collagen VI-containing microfibrils in the pericellular matrix of human chondrocytes

scientific article

WARP is a new member of the von Willebrand factor A-domain superfamily of extracellular matrix proteins

scientific journal article

Why mice have lost genes for COL21A1, STK17A, GPR145 and AHRI: evidence for gene deletion at evolutionary breakpoints in the rodent lineage

scientific article published on 01 September 2004

XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease

scientific article published on 01 July 2019

XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease

scientific article published in September 2015

bfb, a novel ENU-induced blebs mutant resulting from a missense mutation in Fras1

scientific article

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