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List of works by David M Underhill

A pair of 9s: it's in the CARDs

scientific article published in February 2007

A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages

scientific article published on 13 May 2009

Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'.

scientific article published on April 2011

Adaptor protein Lnk inhibits c-Fms-mediated macrophage function

scientific article

Amphiphysin IIm, a Novel Amphiphysin II Isoform, Is Required for Macrophage Phagocytosis

scientific article published in March 2000

Autocrine Type I IFN Signaling in Dendritic Cells Stimulated with Fungal β-Glucans or Lipopolysaccharide Promotes CD8 T Cell Activation

scientific article

Batf3 deficiency is not critical for the generation of CD8α⁺ dendritic cells

scientific article

Beta-glucan recognition by the innate immune system.

scientific article published on July 2009

C9orf72 is required for proper macrophage and microglial function in mice

scientific article published on March 2016

CD4(+) T-cell survival in the GI tract requires dectin-1 during fungal infection

scientific article

Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study

scientific article published on 24 April 2015

Co-operative induction of pro-inflammatory signaling by Toll-like receptors

scientific article

Collaboration between the innate immune receptors dectin-1, TLRs, and Nods.

scientific article published on October 2007

Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

scientific article

Commensal Fungi in Health and Disease.

scientific article published in August 2017

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection.

scientific article

Current understanding of fungal microflora in inflammatory bowel disease pathogenesis

scientific article published on August 2008

Cutting edge: FYCO1 recruitment to dectin-1 phagosomes is accelerated by light chain 3 protein and regulates phagosome maturation and reactive oxygen production

scientific article published on 17 January 2014

Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin

scientific journal article

Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production

scientific article published on 14 June 2005

Dectin-1 and TLRs permit macrophages to distinguish between different Aspergillus fumigatus cellular states

scientific article published in March 2006

Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments.

scientific article

Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells

scientific article published in March 2007

Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens.

scientific article

Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses

scientific journal article

Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce

scientific article published on 7 June 2013

Differential use of CARD9 by dectin-1 in macrophages and dendritic cells

scientific article published on January 2009

Direct Antimicrobial Activity of IFN-β.

scientific article published on 14 April 2017

Dynamic interactions of macrophages with T cells during antigen presentation.

scientific article

Endocytosis and lysosomal delivery of tissue plasminogen activator-inhibitor 1 complexes in Hep G2 cells

scientific article published on December 1992

Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice

scientific article published on 20 September 2018

Failure to induce IFN-β production during Staphylococcus aureus infection contributes to pathogenicity.

scientific article

Frontline Science: Antibiotic treatment routes Mycobacterium avium to phagolysosomes without triggering proinflammatory cytokine production in human Mϕs

scientific article published on 12 June 2020

Fungal Recognition by TLR2 and Dectin-1.

scientific article published on January 2008

Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes

scientific article

Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan

scientific article

Harnessing antifungal immunity in pursuit of a Staphylococcus aureus vaccine strategy

scientific article published on 20 August 2020

Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan

scientific article published on 29 June 2016

Host-microbe interactions: commensal fungi in the gut.

scientific article

Host-microbe interactions: fungi

scientific article published in August 2008

IFN- Enhances Production of Nitric Oxide from Macrophages via a Mechanism That Depends on Nucleotide Oligomerization Domain-2

scientific article published on 3 April 2006

Immune Interactions with Pathogenic and Commensal Fungi: A Two-Way Street

scientific article published in November 2015

Immunity to Commensal Fungi: Detente and Disease

scientific article published on 21 December 2016

Immunological Consequences of Intestinal Fungal Dysbiosis.

scientific article published on 26 May 2016

Inflammatory properties of antibiotic-treated bacteria

scientific article

Information processing during phagocytosis

scientific article published on 15 June 2012

Inhibitory receptor paired Ig-like receptor B is exploited by Staphylococcus aureus for virulence

scientific article published on 14 November 2012

Integration of Toll-like receptor and phagocytic signaling for tailored immunity.

scientific article

Leishmania major activates IL-1 alpha expression in macrophages through a MyD88-dependent pathway

scientific article published on July 2002

Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.

scientific article

Lymphoid-related CD11c+ CD8alpha+ dendritic cells are involved in enhancing herpes simplex virus type 1 latency.

scientific article published on 30 July 2008

MacMARCKS is not essential for phagocytosis in macrophages

scientific article published on December 1998

Macrophage recognition of zymosan particles

scientific article published in June 2003

Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models

scientific article published on 05 March 2019

Malassezia spp. induce inflammatory cytokines and activate NLRP3 inflammasomes in phagocytes

scientific article published on 17 September 2020

Mechanisms of Fc receptor and dectin-1 activation for phagocytosis

scientific article published on 19 June 2012

Mechanisms of phagocytosis in macrophages

scientific article (publication date: 1999)

Mucosal immune responses to fungi and the implications for inflammatory bowel disease

article

Mycobiome: Approaches to analysis of intestinal fungi

scientific article published on 17 April 2015

Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis.

scientific article published on 27 January 2017

O-Acetylation of Peptidoglycan Limits Helper T Cell Priming and Permits Staphylococcus aureus Reinfection.

scientific article published on 20 September 2017

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

scientific article (publication date: 23 March 2012)

Paired Ig-like receptors bind to bacteria and shape TLR-mediated cytokine production

scientific article published on April 2007

Persistent Microvascular Obstruction After Myocardial Infarction Culminates in the Confluence of Ferric Iron Oxide Crystals, Proinflammatory Burden, and Adverse Remodeling

scientific article

Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria.

scientific article published on 26 October 2011

Phagosome maturation: steady as she goes.

scientific article

Physiology and biochemistry of the kidney vacuolar H+-ATPase

scientific article published on January 1996

Plasma membrane V-ATPases in proton-transporting cells of the mammalian kidney and osteoclast

scientific article published in August 1998

Poorly Cross-Linked Peptidoglycan in MRSA Due to mecA Induction Activates the Inflammasome and Exacerbates Immunopathology

scientific article

Preservation of intercalated cell H(+)-ATPase in two patients with lupus nephritis and hyperkalemic distal renal tubular acidosis

scientific article published in July 1997

Striking a balance: fungal commensalism versus pathogenesis

scientific article published on 04 June 2013

The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection

scientific article

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

scientific article

The many faces of ITAMs.

scientific article published on 2 January 2007

The mycobiome of the human urinary tract: potential roles for fungi in urology

scientific article published on January 2017

The mycobiota: interactions between commensal fungi and the host immune system.

scientific article

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

scientific journal article

Time to cast a larger net.

scientific article published in November 2014

Toll gets tied in a knot

scientific article published in August 2003

Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages.

scientific article published on December 1999

Toll-like receptors: key mediators of microbe detection.

scientific article

Toll-like receptors: networking for success.

scientific article

Transcriptional regulation of the vacuolar H(+)-ATPase B2 subunit gene in differentiating THP-1 cells

scientific article

β-Glucan signaling connects phagocytosis to autophagy

scientific article published on 06 June 2013

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