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List of works by James M Brewer

(How) do aluminium adjuvants work?

scientific article

A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation

scientific article published on 22 November 2018

A Novel Dendritic Cell-Induced Model of Erosive Inflammatory Arthritis: Distinct Roles for Dendritic Cells in T Cell Activation and Induction of Local Inflammation

article

A cryptic cycle in haematopoietic niches promotes initiation of malaria transmission and evasion of chemotherapy.

scientific article published on 27 April 2018

A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo

scientific article

Abatacept Inhibition of T Cell Priming in Mice by Induction of a Unique Transcriptional Profile That Reduces Their Ability to Activate Antigen-Presenting Cells

scientific article published on 16 October 2015

Abatacept Limits Breach of Self-Tolerance in a Murine Model of Arthritis via Effects on the Generation of T Follicular Helper Cells

article

Accurate determination of adjuvant-associated protein or peptide by ninhydrin assay

scientific article published on 01 January 1995

Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model

scientific article

Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro

scientific article published on 23 June 2012

Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling

article

Analysis of costimulatory molecule expression on antigen-specific T and B cells during the induction of adjuvant-induced Th1 and Th2 type responses

article

Analysis of intracellular enzyme activity by surface enhanced Raman scattering

scientific article published in November 2013

Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro

article

Antibody responses to Toxoplasma gondii antigen in human peripheral blood lymphocyte-reconstituted severe-combined immunodeficient mice reproduce the immunological status of the lymphocyte donor

article

Antibody responses, cytokine levels and protection of mice immunised with HSV-2 antigens formulated into NISV or ISCOM delivery systems

article

Antigen depot is not required for alum adjuvanticity

scientific article

Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo.

scientific article

Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors

scientific article

Arthritis in space and time--to boldly go!

scientific article published on 09 May 2011

Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging.

scientific article published on 16 October 2015

Cellular imaging in rheumatic diseases

scientific article published on 24 March 2015

Characterization of CD4+ T-cell-dendritic cell interactions during secondary antigen exposure in tolerance and priming

scientific article published in December 2009

Characterization of the anticollagen antibody response in a new model of chronic polyarthritis

article

Congenital toxoplasmosis in the Balb/c mouse: prevention of vertical disease transmission and fetal death by vaccination

article

Cytokines and the mechanisms of action of vaccine adjuvants

scientific article published on 01 December 1997

Designing Lipid Nanostructures for Local Delivery of Biologically Active Macromolecules

article

Detection of Inflammation in Vivo by Surface-Enhanced Raman Scattering Provides Higher Sensitivity Than Conventional Fluorescence Imaging

article

Developing a xenograft model of human vasculature in the mouse ear pinna

scientific article published on 06 February 2020

Direct quantitation of T cell signaling by laser scanning cytometry.

scientific article

Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis

article

Effect of chromium and cobalt ions on primary human lymphocytesin vitro

scientific article published on 29 March 2011

Effects of Streptococcus mutans on dendritic cell activation and function.

scientific article

Effects of host-derived chemokines on the motility and viability of Trypanosoma brucei

scientific article published on 27 December 2018

Host genetic background determines whether IL-18 deficiency results in increased susceptibility or resistance to murine Leishmania major infection

scientific article

Identifying the cells breaching self-tolerance in autoimmunity

scientific article published on 26 April 2010

Imaging T-cell movement in the brain during experimental cerebral malaria.

scientific article

Imaging interactions between the immune and cardiovascular systems in vivo by multiphoton microscopy

scientific article

Immune responses in mice induced by HSV-1 glycoproteins presented with ISCOMs or NISV delivery systems

article

In Vivo Generated Th1 Cells Can Migrate to B Cell Follicles to Support B Cell Responses

article

In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production

article

In situ characterization of CD4+ T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance.

scientific article

In vivo imaging of infection immunology--4I's!

scientific article published on 07 July 2010

In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis

scientific article

In vivo real-time multiphoton imaging of T lymphocytes in the mouse brain after experimental stroke

scientific article

Inducible Costimulatory Molecule-B7-Related Protein 1 Interactions Are Important for the Clonal Expansion and B Cell Helper Functions of Naive, Th1, and Th2 T Cells

scientific article published on 01 March 2003

Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells

scientific article published in July 2004

Interleukin-18 plays a role in both the alum-induced T helper 2 response and the T helper 1 response induced by alum-adsorbed interleukin-12

article

Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes

scientific article

Investigating the immunologic effects of CoCr nanoparticles

scientific article published on 30 June 2009

Lipid vesicle size determines the Th1 or Th2 response to entrapped antigen.

scientific article published in October 1998

Lipid vesicle-entrapped influenza A antigen modulates the influenza A-specific human antibody response in immune reconstituted SCID-human mice

article

Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge

scientific article published on 16 July 2010

Liposomes as possible carriers for lactoferrin in the local treatment of inflammatory diseases.

scientific article published in June 2001

Lymphocyte tracking and interactions in secondary lymphoid organs.

scientific article published on October 2007

MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion

scientific article

Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells

scientific article

Mechanisms of autoimmunity in human diseases: a critical review of current dogma

scientific article published on March 2014

MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis

scientific article

Model answers: Rational application of murine models in arthritis research

scientific article published on 28 November 2017

Multiphoton Microscopy for 3-Dimensional Imaging of Lymphocyte Recruitment Into Apolipoprotein-E–Deficient Mouse Carotid Artery

scientific article published on 01 March 2007

Multispectral oximetry of murine tendon microvasculature with inflammation

scientific article

Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules

scientific article published on 20 July 2014

Murine neutrophils present Class II restricted antigen

scientific article published on 19 March 2008

Neither interleukin-6 nor signalling via tumour necrosis factor receptor-1 contribute to the adjuvant activity of Alum and Freund's adjuvant

scientific article published on 01 January 1998

Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.

scientific article published on 23 January 2017

New views on immunopotentiators in modern vaccines

scientific article published on 01 September 2008

Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.

scientific article

Oral immunisation with peptide and protein antigens by formulation in lipid vesicles incorporating bile salts (bilosomes).

scientific article

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria

scientific article

Plasmacytoid Dendritic Cells Play a Key Role in Promoting Atherosclerosis in Apolipoprotein E–Deficient Mice

scientific article published on 30 August 2012

Plasmacytoid Dendritic Cells Regulate Breach of Self-Tolerance in Autoimmune Arthritis

scientific article published on 01 January 2009

Plasmacytoid dendritic cells: biomarkers or potential therapeutic targets in atherosclerosis?

scientific article published on 08 October 2012

Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease

scientific article published on 17 March 2011

Re: strategies for selective priming of memory B cells

scientific article published on 5 March 2007

Real-time imaging of the cellular interactions underlying tolerance, priming, and responses to infection

scientific article published on February 2008

Regulation of macrophage IL-12 synthesis by Leishmania phosphoglycans

scientific article published on January 1999

Reversal of the TCR stop signal by CTLA-4

scientific article

SipA Activation of Caspase-3 Is a Decisive Mediator of Host Cell Survival at Early Stages of Salmonella enterica Serovar Typhimurium Infection

scientific article

Spatiotemporal Modeling of the Key Migratory Events During the Initiation of Adaptive Immunity

scientific article published on 05 April 2019

Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide

scientific article

Studies on the adjuvant activity of non-ionic surfactant vesicles: adjuvant-driven IgG2a production independent of MHC control

article

Suppression of adaptive immunity to heterologous antigens during Plasmodium infection through hemozoin-induced failure of dendritic cell function

scientific article

TNF-blocking therapies: an alternative mode of action?

scientific article

Th17 effector cells support B cell responses outside of germinal centres

scientific article (publication date: 2012)

The Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses

scientific article

The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4⁺ T cell-priming capacity of dendritic cells

scientific article published on 26 July 2014

The adjuvant activity of non-ionic surfactant vesicles (niosomes) on the BALB/c humoral response to bovine serum albumin ⬇️

scientific article published on April 1, 1992

The demonstration of an essential role for macrophages in the in vivo generation of IgG2a antibodies

scientific article published on 01 July 1994

The influence of follicular migration on T-cell differentiation

scientific article published on March 2004

The type I IFN system in rheumatoid arthritis

scientific article published in April 2010

Tracking dendritic cells in vivo

scientific article published in January 2010

Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation

scientific article published on 11 October 2007

Using bicistronic IL-4 reporter mice to identify IL-4 expressing cells following immunisation with aluminium adjuvant

scientific article published on 31 March 2006

Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections

scientific article published on 24 July 2013

Vesicle size influences the trafficking, processing, and presentation of antigens in lipid vesicles

scientific article published in November 2004

Visualising the interaction of CD4 T cells and DCs in the evolution of inflammatory arthritis.

scientific article published on 22 January 2018

What can transgenic parasites tell us about the development of Plasmodium-specific immune responses?

scientific article published on April 2008

multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy

scientific article published on 29 November 2018

“Immunopotentiators in Modern Vaccines” (IMV-II) held in Malaga, Spain, May 18–20, 2005

article

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