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List of works by Ronit Shiri-Sverdlov

445 PPARA GENE LEVEL DIFFERENTLY AFFECTS LIPID METABOLISM AND INFLAMMATION IN APOLIPOPROTEIN E2 KNOCK-IN MICE

article

A cell-type-specific role for murine Commd1 in liver inflammation

scientific article published on 27 July 2014

A central role for cholesterol metabolism and inflammation during the inhibition of non-alcoholic steatohepatitis with a synthetic PPARα agonist

A liver-specific long noncoding RNA with a role in cell viability is elevated in human nonalcoholic steatohepatitis

scientific article published on 10 January 2017

Antenatal exposure to chorioamnionitis affects lipid metabolism in 7-week-old sheep.

scientific article published in April 2012

Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort

article by J. V. van Vliet-Ostaptchouk et al published 10 October 2006 in Diabetologia

Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation

scientific article published on 2 October 2017

Bone marrow transplantation as an established approach for understanding the role of macrophages in atherosclerosis and the metabolic syndrome

scientific article published on April 2012

Bone marrow transplantation in mice as a tool for studying the role of hematopoietic cells in metabolic and cardiovascular diseases

scientific article published on June 2010

Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice

scientific article published on 20 April 2015

Cathepsin D regulates lipid metabolism in murine steatohepatitis

scientific article

Cholesterol is a significant risk factor for non-alcoholic steatohepatitis

scientific article published on 22 September 2015

Cholesterol-induced hepatic inflammation does not contribute to the development of insulin resistance in male LDL receptor knockout mice.

scientific article published on 18 December 2013

Cholesterol-induced hepatic inflammation does not underlie the predisposition to insulin resistance in dyslipidemic female LDL receptor knockout mice

scientific article

Chorioamnionitis induced hepatic inflammation and disturbed lipid metabolism in fetal sheep.

scientific article published on December 2010

Complement alternative pathway activation in human nonalcoholic steatohepatitis

scientific article

Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice

scientific article published on 08 September 2021

Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions

scientific article published on 23 December 2019

Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity

scientific article

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

scientific article published in August 2008

Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease

scientific article published on 14 April 2020

Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates

scientific article published on 20 December 2005

Elevated granulocyte-colony stimulating factor and hematopoietic stem cell mobilization in Niemann-Pick Type C1 disease

scientific article

Exendin-4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration

scientific article published on February 2014

Exogenously Added Oxyphytosterols Do Not Affect Macrophage-Mediated Inflammatory Responses

article

Experience at Sheba Hospital in oncogenetic counseling and genetic testing of women with a high risk for breast and ovarian cancer

scientific article published on 01 April 1998

FXR agonism protects against liver injury in a rat model of intestinal failure-associated liver disease

scientific article published on 15 October 2017

Familial clustering of site-specific cancer risks associated with BRCA1 and BRCA2 mutations in the Ashkenazi Jewish population

scholarly article

Genetic counseling in hereditary breast/ovarian cancer in Israel: Psychosocial impact and retention of genetic information

scholarly article by Michal DiCastro et al published 29 July 2002 in American Journal of Medical Genetics Part A

Genomic analysis of the response of mouse models to high-fat feeding shows a major role of nuclear receptors in the simultaneous regulation of lipid and inflammatory genes

scientific article published on 16 March 2005

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HHEX gene polymorphisms are associated with type 2 diabetes in the Dutch Breda cohort

article

Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr-/- mice on a high-fat, high-cholesterol diet

scientific article published on 18 October 2019

Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice

scientific article published on 02 October 2014

Identification of TUB as a novel candidate gene influencing body weight in humans.

scientific article

Inflammatory Bowel Disease: A Stressed "Gut/Feeling"

scientific article published on 30 June 2019

Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague–Dawley Rats †

scientific article published on 04 May 2019

Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells

scientific article

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice

scientific article published on 29 January 2010

LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease

scientific article

Liver manipulation during liver surgery in humans is associated with hepatocellular damage and hepatic inflammation

scientific article published on 29 January 2013

Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease ⬇️

scientific article

Low profile high value target: The role of OxLDL in cancer

scientific article published on 31 August 2019

Lysosomal cholesterol accumulation: driver on the road to inflammation during atherosclerosis and non-alcoholic steatohepatitis

scientific article published on 16 March 2014

MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis

scientific article published on 09 September 2016

MSP: an emerging player in metabolic syndrome

scientific article

Macrophage Stimulating Protein Enhances Hepatic Inflammation in a NASH Model

scientific article

Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice

scientific article published on 02 December 2013

Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice

scientific article published on 16 December 2016

Mediators of gut mucosal immunity and inflammation.

scientific article published on 19 April 2015

Modulating liver inflammation: a crucial role for cholesterol

article published in 2008

Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids

scientific article published on 22 May 2017

Mutational analyses ofBRCA1 andBRCA2 in Ashkenazi and non-Ashkenazi Jewish women with familial breast and ovarian cancer

article

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice

scientific article

NAFLD Preclinical Models: More than a Handful, Less of a Concern?

scientific article published on 08 February 2020

NASH and atherosclerosis are two aspects of a shared disease: central role for macrophages

scientific article published on 03 September 2011

Neutrophil-derived myeloperoxidase aggravates non-alcoholic steatohepatitis in low-density lipoprotein receptor-deficient mice

scientific article

Non-alcoholic steatohepatitis: the role of oxidized low-density lipoproteins

scientific article

Nonalcoholic Fatty Liver Disease

scientific article published on 18 March 2020

Nonalcoholic fatty liver disease: A main driver of insulin resistance or a dangerous liaison?

scholarly article by Nanda Gruben et al published November 2014 in BBA: Molecular Basis of Disease

Oxidised plant sterols as well as oxycholesterol increase the proportion of severe atherosclerotic lesions in female LDL receptor+/ - mice.

scientific article published on 18 June 2013

Oxidized LDL at the crossroads of immunity in non-alcoholic steatohepatitis

scientific article

Oxidized LDL in inflammation: from bench to bedside

scientific article

P105 Biliary drainage in a rat: a long-term continuous drainage model resulting in liver damage and an altered FXR pathway, lipid and cholesterol metabolism

P32 Liver mobilisation during liver resection induces immediate and profound hepatocellular damage and inflammation in humans

Parenteral nutrition dysregulates bile salt homeostasis in a rat model of parenteral nutrition-associated liver disease.

scientific article published on 24 September 2016

Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice

scientific article

Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals

scientific article published on 30 September 2020

Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation

scientific article published on 03 March 2015

Plasma IL-1 receptor antagonist levels correlate with the development of non-alcoholic steatohepatitis

scientific article published on 19 November 2015

Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans

scientific article published on 05 November 2019

Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

scientific article published on 6 December 2016

Plasma cholesteryl ester transfer protein is predominantly derived from Kupffer cells

scientific article published on 14 July 2015

Pneumococcal Immunization Reduces Neurological and Hepatic Symptoms in a Mouse Model for Niemann-Pick Type C1 Disease

scientific article published on 01 January 2018

Polymorphisms of the TUB gene are associated with body composition and eating behavior in middle-aged women.

scientific article

Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr-/- mice.

scientific article published on 20 October 2016

Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans

scientific article

Response to Tauriainen et al. . 2018

scientific article published on 31 October 2018

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

scientific article

Serum TG-lowering properties of plant sterols and stanols are associated with decreased hepatic VLDL secretion

scientific article

Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling

scientific article published on 29 May 2020

Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells

scientific article

Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice

scientific article

TUB gene expression in hypothalamus and adipose tissue and its association with obesity in humans.

scientific article

TUB is a candidate gene for late-onset obesity in women

scientific article published on 23 October 2007

The Cholesterol Derivative 27-Hydroxycholesterol Reduces Steatohepatitis in Mice

scientific article published on 03 October 2012

The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management

scientific article published on 13 July 2020

The Tyr978X BRCA1 Mutation in Non-Ashkenazi Jews: Occurrence in High-Risk Families, General Population and Unselected Ovarian Cancer Patients

The Tyr978X BRCA1 mutation: occurrence in non-Jewish Iranians and haplotype in French-Canadian and non-Ashkenazi Jews

article

The immunity-diet-microbiota axis in the development of metabolic syndrome

scientific article

Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation

scientific article

Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model

scientific article published on 10 January 2013

Ultrasonic Perfluorohexane-Loaded Monocyte Imaging: Toward a Minimally Invasive Technique for Selective Detection of Liver Inflammation in Fatty Liver Disease

scientific article published on 9 October 2017

Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice

scientific article

Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice

scientific article

Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet.

scientific article

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