List of works by Angelo D'Alessandro

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

scientific article published on 21 July 2021

A SIX1/EYA2 small molecule inhibitor disrupts EMT and metastasis

scientific article published on 27 April 2020

A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer.

scientific article

A mass spectrometry-based targeted metabolomics strategy of human blastocoele fluid: a promising tool in fertility research.

scientific article published on 21 October 2011

A robust high resolution reversed-phase HPLC strategy to investigate various metabolic species in different biological models.

scientific article published on 24 January 2011

A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways

scientific article published on 13 February 2017

ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.

scientific article published on 10 October 2016

Absence of aquaporin-4 in skeletal muscle alters proteins involved in bioenergetic pathways and calcium handling.

scientific article

Alterations of red blood cell metabolome during cold liquid storage of erythrocyte concentrates in CPD-SAGM.

scientific article published on 20 March 2012

AltitudeOmics: Red Blood Cell Metabolic Adaptation to High Altitude Hypoxia

scientific article published on 20 September 2016

An update on red blood cell storage lesions, as gleaned through biochemistry and omics technologies.

scientific article

Analysis of TAp73-dependent signaling via omics technologies

scientific article published on 22 August 2013

Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

scientific article published on 01 July 2019

Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia

scientific article published in August 2016

Blood bank storage of red blood cells increases RBC cytoplasmic membrane order and bending rigidity

scientific article published on 12 November 2021

Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress

scientific article published on 04 November 2020

Blood-related proteomics

scientific article

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

scientific article published on 27 December 2016

CO2 -dependent metabolic modulation in red blood cells stored under anaerobic conditions.

scientific article published on 19 October 2015

COVID-19 infection results in alterations of the kynurenine pathway and fatty acid metabolism that correlate with IL-6 levels and renal status

scientific article published on 17 May 2020

CPT1A Over-Expression Increases Reactive Oxygen Species in the Mitochondria and Promotes Antioxidant Defenses in Prostate Cancer

scientific article published on 18 November 2020

Cadmium stress responses in Brassica juncea: hints from proteomics and metabolomics

scientific article

Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells.

scientific article published on 13 June 2013

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

scientific article published on 13 January 2021

Characterization of rapid extraction protocols for high-throughput metabolomics

scientific article published on 6 June 2017

Chianina beef tenderness investigated through integrated Omics.

scientific article published on 4 April 2012

Citrate metabolism in red blood cells stored in additive solution-3.

scientific article published on 4 November 2016

Classic and alternative red blood cell storage strategies: seven years of "-omics" investigations

scientific article

Clickable Methyltetrazine-Indocarbocyanine Lipids: A Multicolor Tool Kit for Efficient Modifications of Cell Membranes

scientific article published on 03 May 2019

Clinical metabolomics: the next stage of clinical biochemistry

scientific article

Comparative proteomics and transcriptomics analyses of livers from two different Bos taurus breeds: "Chianina and Holstein Friesian".

scientific article

Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.

scientific article published on 23 December 2015

Coordination between Drosophila Arc1 and a specific population of brain neurons regulates organismal fat

scientific article (publication date: 15 September 2015)

Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II

scientific article published on 17 May 2019

DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

scientific article published on 09 March 2022

Data on how several physiological parameters of stored red blood cells are similar in glucose 6-phosphate dehydrogenase deficient and sufficient donors

scientific article

Deoxygenation of leucofiltered erythrocyte concentrates preserves proteome stability during storage in the blood bank

scientific article

Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice

scientific article published on 01 August 2019

Docosohaexanoic acid-supplemented PACA44 cell lines and over-activation of Krebs cycle: an integrated proteomic, metabolomic and interactomic overview.

scientific article published on 23 June 2011

Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion

scientific article published on 23 March 2020

Donor-dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity

scientific article published on 19 August 2020

Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer

scientific article published on 18 November 2019

Early hemorrhage triggers metabolic responses that build up during prolonged shock.

scientific article published on 15 April 2015

Effects of aged stored autologous red blood cells on human plasma metabolome

scientific article published on 01 March 2019

Ethyl glucuronide, a marker of alcohol consumption, correlates with metabolic markers of oxidant stress but not with hemolysis in stored red blood cells from healthy blood donors

scientific article published on 08 May 2020

Evidence for structural protein damage and membrane lipid remodeling in red blood cells from COVID-19 patients

scientific article published on 30 June 2020

Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients

scientific article published on 26 October 2020

Fine-Tuning of CD8(+) T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus

scientific article published on 23 May 2016

Glucose 6-phosphate dehydrogenase deficient subjects may be better "storers" than donors of red blood cells

scientific article published on 14 April 2016

Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock

scientific article published on 3 September 2016

Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells

scientific article published on 01 May 2021

Haemoglobin glycation (Hb1Ac) increases during red blood cell storage: a MALDI-TOF mass-spectrometry-based investigation.

scientific article

Hemoglobin oxidation at functional amino acid residues during routine storage of red blood cells

scientific article published in October 2015

How has proteomics informed transfusion biology so far?

scientific article published on 08 February 2010

Human milk proteins: an interactomics and updated functional overview

scientific article published on July 2010

Hydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization.

scientific article published on 3 October 2017

Hypertonic Saline Primes Activation of the p53-p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines

scientific article published on 16 August 2016

Hypoxic storage of red blood cells improves metabolism and post-transfusion recovery

scientific article published on 27 February 2020

Identification of Infants at Risk for Chronic Lung Disease at Birth. Potential for a Personalized Approach to Disease Prevention

scientific article published on 14 June 2017

Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation.

scientific article

Impact of taurine on red blood cell metabolism and implications for blood storage

scientific article published on 27 April 2020

In reply to: "Further comments on platelet proteomics in Transfusion Medicine"

scientific article published on 4 June 2013

In silico analyses of proteomic data suggest a role for heat shock proteins in umbilical cord blood hematopoietic stem cells.

scientific article

Investigation of the effects of storage and freezing on mixes of heavy-labeled metabolite and amino acid standards

scientific article published on 14 September 2017

Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer

scientific article published on 19 March 2021

Leucoreduction of blood components: clinical and molecular evidence

scientific article published on 16 December 2015

Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis.

scientific article

Love me tender: an Omics window on the bovine meat tenderness network.

scientific article published on 21 February 2012

Lymph formation, composition and circulation: a proteomics perspective

scientific article published on 18 March 2015

Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots

scientific article published on 26 April 2019

Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD

scientific article published in 2022

Meat quality of the longissimus lumborum muscle of Casertana and Large White pigs: metabolomics and proteomics intertwined.

scientific article published on 8 September 2011

Meat science: From proteomics to integrated omics towards system biology

scientific article published on 6 November 2012

Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer

scientific article published on 10 February 2021

Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.

scientific article published on 25 August 2016

Metabolic alterations mediated by STAT3 promotes drug persistence in CML

scientific article published on 12 June 2021

Metabolic characterization of plasma and cyst fluid from cystic precursors to pancreatic cancer patients reveal metabolic signatures of bacterial infection

scientific article published on 04 November 2020

Metabolic impact of red blood cell exchange with rejuvenated red blood cells in sickle cell patients

scientific article published on 05 August 2019

Metabolic phenotypes of standard and cold-stored platelets

scientific article published on 27 December 2019

Metabolomics Analysis of Human Vitreous in Diabetic Retinopathy and Rhegmatogenous Retinal Detachment

scientific article published on 19 June 2018

Metabolomics and cancer drug discovery: let the cells do the talking.

scientific article published on 4 October 2011

Metabolomics in transfusion medicine

scientific article published on 12 December 2015

Metabolomics of AS-5 RBC supernatants following routine storage

scientific article

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia

scientific article published on 23 January 2020

Murine macrophages response to iron

scientific article published on 23 July 2012

Native analysis of plasma-derived clotting factor VIII concentrates: “Sponge effect” and contaminants

scientific article published on 01 April 2012

Native protein complexes in the cytoplasm of red blood cells.

scientific article published on 19 June 2013

Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers

scientific article published on 08 May 2020

Nitrogen recycling buffers against ammonia toxicity from skeletal muscle breakdown in hibernating arctic ground squirrels

scientific article published on 07 December 2020

Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge

scientific article published on 28 August 2019

Omics integrating physical techniques: aged Piedmontese meat analysis

scientific article published on 5 October 2014

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease

scientific article published in 2021

Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells

scientific article published on 14 June 2019

Pathologic metabolism: an exploratory study of the plasma metabolome of critical injury

scientific article

Pharmacoproteomics: a chess game on a protein field

scientific article published on 20 October 2010

Plasma First Resuscitation Reduces Lactate Acidosis, Enhances Redox Homeostasis, Amino Acid and Purine Catabolism in a Rat Model of Profound Hemorrhagic Shock

scientific article published on 6 February 2016

Plasma QconCATs reveal a gender-specific proteomic signature in apheresis platelet plasma supernatants

scientific article published on 2 March 2015

Plasma-derived clotting factor VIII: heterogeneity evaluation in the quest for potential inhibitory-antibody stimulating factors.

scientific article published on 14 October 2011

Preface to the Special Issue: Integrated omics

scientific article published on 16 October 2012

Production of the phytoalexins trans-resveratrol and delta-viniferin in two economy-relevant grape cultivars upon infection with Botrytis cinerea in field conditions.

scientific article

Protective effects of the neuropeptides PACAP, substance P and the somatostatin analogue octreotide in retinal ischemia: a metabolomic analysis

scientific article published on 11 February 2014

Proteome changes in platelets after pathogen inactivation--an interlaboratory consensus

scientific article published on 25 February 2014

Proteomic analysis of platelets treated with gamma irradiation versus a commercial photochemical pathogen reduction technology.

scientific article published on 10 January 2013

Proteomic and metabolic profiles of Cakile maritima Scop. Sea Rocket grown in the presence of cadmium

scientific article published in April 2015

Proteomics and metabolomics in cancer drug development

scientific article published on October 2013

Proteomics and transcriptomics investigation on longissimus muscles in Large White and Casertana pig breeds.

scientific article published on 9 November 2010

Proteomics for quality-control processes in transfusion medicine

scientific article published on 25 May 2010

Proteomics of apheresis platelet supernatants during routine storage: Gender-related differences

scientific article published on 06 September 2014

Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells

scientific article

Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel

scientific article published on 28 February 2019

Red Blood Cell Proteasome in Beta-Thalassemia Trait: Topology of Activity and Networking in Blood Bank Conditions

scientific article published in 2021

Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging

scientific article published on 21 December 2017

Red blood cell metabolism under prolonged anaerobic storage.

scientific article published on 20 February 2013

Red blood cell processing for cryopreservation: from fresh blood to deglycerolization

scientific article published on 15 March 2012

Red blood cell storage in additive solution-7 preserves energy and redox metabolism: a metabolomics approach

scientific article

Red blood cell storage: the story so far.

scientific article

Redox proteomics and drug development.

scientific article published on 15 January 2011

Reprogramming of red blood cell metabolism in Zika virus–infected donors

scientific article published in 2022

Response to "Platelets proteomics in transfusion medicine: a reality with challenging but promising future".

scientific article

Routine storage of red blood cell (RBC) units in additive solution-3: a comprehensive investigation of the RBC metabolome.

scientific article published on 30 December 2014

Shock releases bile acid inducing platelet inhibition and fibrinolysis

scientific article published on 29 January 2015

Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans.

scientific article published on 31 March 2016

Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia

scientific article published on 15 July 2016

Stored RBC metabolism as a function of caffeine levels

scientific article published on 11 May 2020

Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions: a metabolomics overview

scientific article

Supernatant protein biomarkers of red blood cell storage hemolysis as determined through an absolute quantification proteomics technology

scientific article published on 26 January 2016

Supplementation of anti-oxidants in leucofiltered erythrocyte concentrates: assessment of morphological changes through scanning electron microscopy.

scientific article

TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging

scientific article published on 16 July 2019

Targeted mass spectrometry-based metabolomic profiling through multiple reaction monitoring of liver and other biological matrices.

scientific article published in January 2012

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

scientific article published in 2021

Testosterone replacement therapy in blood donors modulates erythrocyte metabolism and susceptibility to hemolysis in cold storage

scientific article published on 18 October 2020

The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease

scientific article published on 30 November 2020

The Post-Storage Performance of RBCs from Beta-Thalassemia Trait Donors Is Related to Their Storability Profile

scientific article published in 2021

The SODyssey: superoxide dismutases from biochemistry, through proteomics, to oxidative stress, aging and nutraceuticals

scientific article published on June 2011

The bovine milk proteome: cherishing, nourishing and fostering molecular complexity. An interactomics and functional overview.

scientific article published on 29 September 2010

The egg white and yolk interactomes as gleaned from extensive proteomic data

scientific article

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

scientific article published in Nature Communications

The hepatic microenvironment uniquely protects leukemia cells through induction of growth and survival pathways mediated by LIPG

scientific article published on 07 October 2020

The red blood cell proteome and interactome: an update

scientific article published on January 2010

The role of antenatal immunoprophylaxis in the prevention of maternal-foetal anti-Rh(D) alloimmunisation.

scientific article

Three-minute method for amino acid analysis by UHPLC and high-resolution quadrupole orbitrap mass spectrometry

scientific article

Time-course investigation of SAGM-stored leukocyte-filtered red bood cell concentrates: from metabolism to proteomics

scientific article

Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron

scientific article published on 24 September 2019

Trauma/hemorrhagic shock instigates aberrant metabolic flux through glycolytic pathways, as revealed by preliminary (13)C-glucose labeling metabolomics

scientific article published on 5 August 2015

Troubleshooting in platelet storage temperature and new perspectives through proteomics

scientific article published on June 2010

Umbilical cord blood stem cells: towards a proteomic approach

scientific article published on 24 June 2009

Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma

scientific article published on 6 February 2014

Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension

scientific article published on 01 October 2018

Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients

scientific article published on 8 August 2015

We are what we eat: food safety and proteomics

scientific article published on 20 October 2011

miR-143 regulates hexokinase 2 expression in cancer cells

scientific article

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