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List of works by Michael A McGuckin

A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system.

scientific article

A novel microbiota stratification system predicts future exacerbations in bronchiectasis

scientific article (publication date: May 2014)

A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity

scientific article

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

scientific article

Aberrant mucin glycoprotein patterns of chronic rhinosinusitis patients with bacterial biofilms

scientific article published on September 2010

Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome.

scientific article

Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation

scientific article

An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity.

scientific article

Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women ⬇️

scientific article published on July 1, 1998

CA15-3, CASA, MSA, and TPS as diagnostic serum markers in breast cancer ⬇️

scientific article published on 01 June 1995

Campylobacter jejuni response to human mucin MUC2: modulation of colonization and pathogenicity determinants

scientific article

Carbohydrate binding and gene expression by in vitro and in vivo propagated Campylobacter jejuni after immunomagnetic separation.

scientific article

Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol.

scientific article published on 26 March 2016

Detecting, Visualising, and Quantifying Mucins

scientific article published on 01 January 2012

Dietary Antigens in Crohn's Disease

scientific article published on 06 January 2009

Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

scientific article published in 2021

ER stress and the unfolded protein response in intestinal inflammation.

scientific article published on 25 March 2010

Effect of MUC1 length polymorphisms on the NLRP3 inflammasome response of human macrophages

scientific article published on 15 June 2019

Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial.

scientific article published on March 2013

Effects of photoperiod on the reproductive physiology of male flying foxes, Pteropus poliocephalus

scientific article published on 01 January 1992

Endocrine impact of Helicobacter pylori: focus on ghrelin and ghrelin o-acyltransferase

scientific article published on March 2011

Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate

scientific article published on 8 November 2016

Epithelial Sel1L is required for the maintenance of intestinal homeostasis

scientific article published on 2 December 2015

Evaluation of two new assays for tumor-associated antigens, CASA and OSA, found in the serum of patients with epithelial ovarian carcinoma—Comparison with CA125 ⬇️

scientific article published on 01 May 1990

Expression of MUC1 splice variants in benign and malignant ovarian tumours

scientific article published on 14 June 2002

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype

scientific article published on 28 June 2013

Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice

scientific article published on 22 March 2012

Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice

scientific article

Ghrelin in gastrointestinal disease.

scientific article published on 30 March 2011

Goblet cells as mucosal sentinels for immunity

scientific article published on 25 January 2017

Heterogeneity in production, secretion and glycosylation of MUC1 epithelial mucin by primary cultures of ovarian carcinoma ⬇️

scientific article published on 01 November 1995

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

scientific article published on 28 June 2016

IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells.

scientific article published on 31 October 2012

IgG Antibodies Against Common Gut Bacteria Are More Diagnostic for Crohn's Disease Than IgG Against Mannan or Flagellin

scientific article published on 09 October 2007

Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion

scientific article

Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice

article

Intestinal barrier dysfunction in inflammatory bowel diseases.

scientific article published on January 2009

Intestinal secretory cell ER stress and inflammation

scientific article published in August 2011

KCNN4 gene variant is associated with ileal Crohn's Disease in the Australian and New Zealand population

scientific article published on 20 April 2010

Listeria monocytogenes internalins bind to the human intestinal mucin MUC2.

scientific article published on 8 March 2008

Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry

scientific article published on 9 March 2010

MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy

scientific article published in October 2009

MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance

scientific article published on 16 February 2017

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

scientific article published on 19 August 2019

MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target

scientific article published on 11 July 2016

Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial.

scientific article published on 27 July 2016

Matrix metalloproteinases vary with airway microbiota composition and lung function in non-cystic fibrosis bronchiectasis

scientific article

Muc1 Limits Helicobacter felis Binding to Gastric Epithelial Cells But Does not Limit Colonization and Gastric Pathology Following Infection

scientific article published on 01 December 2008

Muc1 mucin limits both Helicobacter pylori colonization of the murine gastric mucosa and associated gastritis.

scientific article

Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells

scientific article

Mucin dynamics and enteric pathogens.

scientific article published on April 2011

Mucin dynamics in intestinal bacterial infection

scientific article

Mucins in the mucosal barrier to infection.

scientific article published on 05 March 2008

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

scientific article published on 20 July 2010

Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model.

scientific article published on May 2015

No evidence of the unfolded protein response in patients with chronic hepatitis C virus infection

scientific article published in February 2011

O-Linked glycome and proteome of high-molecular-mass proteins in human ovarian cancer ascites: Identification of sulfation, disialic acid and O-linked fucose

scientific article published on 14 March 2012

Oxidative and endoplasmic reticulum stress in respiratory disease.

scientific article published on 13 June 2018

Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes

scientific article

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment

scientific article

Peritoneal fluid from ovarian cancer patients stimulates MUC1 epithelial mucin expression in ovarian cancer cell lines ⬇️

scientific article published on May 4, 1998

Progesterone stimulates production and secretion of MUC1 epithelial mucin in steroid-responsive breast cancer cell lines ⬇️

scientific article published on April 1, 1998

Reduced mucin sulfonation and impaired intestinal barrier function in the hyposulfataemic NaS1 null mouse.

scientific article

Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells

scientific article published on 22 November 2013

Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier

scientific article

Serum markers casa, cea, cyfra-21-1, msa, nse, tpa and tps in lung-cancer ⬇️

scientific article published on 01 May 1994

Spontaneous apoptosis of blood dendritic cells in patients with breast cancer.

scientific article

Structure and function of the polymeric mucins in airways mucus.

scientific article

Suppressor of cytokine signalling gene expression is elevated in breast carcinoma

scientific article published on August 2003

T Cell Transfer Model of Colitis: A Great Tool to Assess the Contribution of T Cells in Chronic Intestinal Inflammation

scientific article published on 01 January 2012

Techniques for Assessment of Interactions of Mucins with Microbes and Parasites In Vitro and In Vivo

scientific article published on 01 January 2012

The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome

scientific article published on 8 April 2015

The MUC13 cell surface mucin is highly expressed by human colorectal carcinomas

scientific article published on 13 March 2007

The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis.

scientific article published on 2 June 2011

The interplay between endoplasmic reticulum stress and inflammation.

scientific article published on 17 January 2012

There is a 'uc' in mucus, but is there mucus in UC?

scientific article published on 17 April 2013

ZAP-70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice.

scientific article

β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice

article

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