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List of works by Philip R Krause

A VP26-mNeonGreen Capsid Fusion HSV-2 Mutant Reactivates from Viral Latency in the Guinea Pig Genital Model with Normal Kinetics.

scientific article published on 8 May 2018

A novel latency-active promoter is contained within the herpes simplex virus type 1 UL flanking repeats.

scientific article published on April 1994

A review of algorithms for molecular sequence comparison

scientific article published on February 1991

A vaccine measured with a highly variable assay: rabies

scientific article published on 20 October 2009

Adventitious agents and vaccines

scientific article published on January 2001

An HSV-1 chimeric containing HSV-2 latency associated transcript (LAT) sequences has significantly reduced adrenergic reactivation in the rabbit eye model

scientific article

An acutely and latently expressed herpes simplex virus 2 viral microRNA inhibits expression of ICP34.5, a viral neurovirulence factor

scholarly article

An annual vaccine: seasonal influenza

scientific article

Analysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcripts

scientific article published in May 1995

Animal models for COVID-19

scientific article published on 23 September 2020

Approaches to demonstration of Ebola virus vaccine efficacy

scientific article published on 17 May 2015

COVID-19 vaccine trials should seek worthwhile efficacy

scientific article published on 27 August 2020

Characterization of herpes simplex virus 2 primary microRNA Transcript regulation

scientific article

Clinical Development Strategies and Considerations for Zika Vaccine Licensure

scientific article published in December 2017

Conceptual and experimental approaches to address product safety issues raised by novel cell substrates.

scientific article

Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks

scientific article published on 01 April 2020

Demonstrating vaccine effectiveness during a waning epidemic: A WHO/NIH meeting report on approaches to development and licensure of Zika vaccine candidates

article

Desirability and feasibility of a vaccine against cytomegalovirus

scientific article published on April 2013

Development of Resistance to Acyclovir during Chronic Infection with the Oka Vaccine Strain of Varicella‐Zoster Virus, in an Immunosuppressed Child ⬇️

scientific article published on September 26, 2003

Development of herpes simplex virus disease in patients who are receiving cidofovir

scientific article

Discovery of a bovine enterovirus in alpaca

scientific article

Disseminated rashes and varicella vaccine

scientific article published on 01 April 2001

Efficacy, immunogenicity, safety, and use of live attenuated chickenpox vaccine

scientific article

Emergency Use Authorization of Covid Vaccines - Safety and Efficacy Follow-up Considerations

scientific article published on 16 October 2020

Evaluating human trials: FDA's role

scientific article published on 21 June 2018

Evaluation of cells and biological reagents for adventitious agents using degenerate primer PCR and massively parallel sequencing

scientific article

Evidence for frequent reactivation of the Oka varicella vaccine strain in healthy vaccinees

scientific article published on 01 January 2001

Goals of stability evaluation throughout the vaccine life cycle

scientific article published on 22 September 2009

Herpes Simplex Virus 2 Latency-Associated Transcript (LAT) region mutations do not identify a role for LAT-Associated Micro RNAs in viral reactivation in the Guinea Pig Genital Model.

scientific article published on 2 May 2018

Herpes Simplex Virus 2 in Autonomic Ganglia: Evidence for Spontaneous Reactivation

scientific article published on 15 May 2019

Herpes simplex virus 2 microRNA miR-H6 is a novel latency-associated transcript-associated microRNA, but reduction of its expression does not influence the establishment of viral latency or the recurrence phenotype

scientific article

Herpes simplex virus ICP27 regulates alternative pre-mRNA polyadenylation and splicing in a sequence-dependent manner

scientific article published on 10 October 2016

Herpes simplex virus latency-associated transcript sequence downstream of the promoter influences type-specific reactivation and viral neurotropism

scientific article published on 4 April 2007

Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts.

scientific article published on 6 December 2006

Herpesvirus vaccines. Development, controversies, and applications.

scientific article

Hidden regulation of herpes simplex virus 1 pre-mRNA splicing and polyadenylation by virally encoded immediate early gene ICP27

scientific article published on 17 June 2019

Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2.

scientific article

Immunology of protection from Ebola virus infection

scientific article published on May 2015

Induction and enhancement of immune responses to herpes simplex virus type 2 in humans by use of a recombinant glycoprotein D vaccine

scientific article published in May 1993

Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes

scientific article published on December 2014

Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia.

scientific article published on 03 June 2009

Latency-associated transcript (LAT) exon 1 controls herpes simplex virus species-specific phenotypes: reactivation in the guinea pig genital model and neuron subtype-specific latent expression of LAT

scientific article published on 29 July 2009

Live oral poliovirus vaccines and simian cytomegalovirus

scientific article published on September 2002

Live oral poliovirus vaccines do not contain detectable simian virus 40 (SV40) DNA.

scientific article published in March 2000

Maintaining confidentiality of emerging results in COVID-19 vaccine trials is essential

scientific article published on 27 October 2020

Molecular and infectivity studies of porcine circovirus in vaccines

scientific article published on 11 May 2011

Novel less-abundant viral microRNAs encoded by herpes simplex virus 2 latency-associated transcript and their roles in regulating ICP34.5 and ICP0 mRNAs.

scientific article

Optimization of virus detection in cells using massively parallel sequencing

scientific article published on 3 December 2013

Pharmacoepidemiologic implications of erroneous varicella vaccinations in pregnancy through confusion with Varicella zoster immune globulin

scientific article published on 01 December 2002

Placebo-Controlled Trials of Covid-19 Vaccines - Why We Still Need Them

scientific article published on 02 December 2020

Placebo-controlled trial of vaccination with recombinant glycoprotein D of herpes simplex virus type 2 for immunotherapy of genital herpes

scientific article

Priorities for CMV vaccine development

scientific article

Quantity of latency-associated transcript produced by herpes simplex virus is not predictive of the frequency of experimental recurrent genital herpes

scientific article published in May 1994

Regulating vaccines at the FDA: development and licensure of Zika vaccines

scientific article

Regulatory approaches for control of viral contamination of vaccines

scientific article published on 01 November 2011

Reply to "Varicella vaccine revisited"

scientific article published on 01 December 2000

Safety of viral DNA in biological products.

scientific article

Simian cytomegalovirus encodes five rapidly evolving chemokine receptor homologues.

scientific article published on January 2004

Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice.

scientific article

Spread of herpes simplex virus to the spinal cord is independent of spread to dorsal root ganglia

scientific article

Stability evaluation of vaccines

scientific article published on 26 September 2009

Tendency to serious sequelae of infection with the human immunodeficiency virus in sibships with hemophilia

scientific article

The 2.2-kilobase latency-associated transcript of herpes simplex virus type 2 does not modulate viral replication, reactivation, or establishment of latency in transgenic mice

scientific article

The characteristic site-specific reactivation phenotypes of HSV-1 and HSV-2 depend upon the latency-associated transcript region

scientific article

The comparative biology of latent herpes simplex virus type 1 and type 2 infections: latency-associated transcript promoter activity and expression in vitro and in infected mice

scientific article published in February 1998

The potential role of advanced technologies for virus detection in development and regulation of vaccines

scientific article

Towards dynamic monitoring of cell cultures using high throughput sequencing

scientific article published on 11 January 2019

Universal virus detection by degenerate-oligonucleotide primed polymerase chain reaction of purified viral nucleic acids

scientific article

Use of DOP-PCR in Non-Specific Virus Detection

scientific article published in November 2011

Use of a universal virus detection assay to identify human metapneumovirus in a hematopoietic stem cell transplant recipient with pneumonia of unknown origin

scientific article

Varicella vaccination: evidence for frequent reactivation of the vaccine strain in healthy children

scientific article published on April 2000

Zoster and its complications

scientific article published on 01 October 1990

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